Adverse childhood experiences, alcohol consumption, and the modifying role of social participation

Population-based study of adults in southwestern Uganda

Bibliographic Data

ID21257616
AuthorsScholastic Ashaba (0000-0002-5822-2488, Mbarara University of Science and Technology, corresponding author), Bernard Kakuhikire (0000-0001-5346-4368, Mbarara University of Science and Technology), Charles Baguma (0000-0003-1936-0244, Mbarara University of Science and Technology), Emily N Satinsky (0000-0003-0666-6009, University of Southern California), Jessica M Perkins (0000-0002-5475-8816, Vanderbilt University), Justin D Rasmussen (0000-0001-7806-1805, Duke University), Christine E Cooper-Vince (0000-0002-5043-6342, University of Geneva), Phionah Ahereza (Mbarara University of Science and Technology), Patrick Gumisiriza (Mbarara University of Science and Technology), Justus Kananura (Mbarara University of Science and Technology), David R Bangsberg (0000-0002-6352-8908, Portland State University), Alexander C Tsai (0000-0001-6397-7917, Harvard University)
Year2022
Volume2
Pages100062
Publication date2022-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueSSM - Mental Health (JOURNAL)
Journal identifiersISSN: 2666-5603 • E-ISSN: 2666-5603
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.ssmmh.2022.100062
PMID35463801
OpenAlexW4210481547
LanguageEN
Citations received7
References cited101

Background: Adverse childhood experiences (ACEs) include multiple forms of child maltreatment, including abuse and neglect, as well as other forms of household dysfunction. Studies from Uganda have revealed a high prevalence of child abuse, as well as one of the highest levels of alcohol consumption in Africa. Few population-based studies from Africa have estimated associations between ACEs and adult alcohol use, or assessed the potential buffering effects of social participation. Methods: This cross-sectional, population-based study was conducted in a rural parish in southwestern Uganda between 2016 and 2018. We assessed self-reported ACEs using a modified version of the Adverse Childhood Experiences - International Questionnaire (ACE-IQ) scale. We measured heavy alcohol consumption using a 3-item scale previously validated in this population. We measured social participation using a 10-item scale eliciting participants' membership and participation in different community groups over the past two months. We fitted multivariable Poisson regression models to estimate the associations between ACEs and heavy alcohol consumption, and to assess for the potential buffering effects of social participation. Results: We estimated statistically significant associations between the total ACE score and heavy alcohol consumption (adjusted relative risk [ARR] per ACE=1.17; 95% CI, 1.09-1.25; P ≤0.001). Social participation had a statistically significant moderating effect on the association between total ACE score and heavy alcohol consumption (P=0.047 for interaction): the estimated association between total ACE score and heavy alcohol consumption among study participants who did not participate in a community group was larger, with a narrower confidence interval (ARR=1.21 per ACE; 95% CI, 1.11-1.33; P<0.001), while the estimated association among study participants who did participate in a community group was smaller and less precisely estimated (ARR=1.12 per ACE; 95% CI, 1.02-1.24; P=0.02). Conclusions: Our findings demonstrate an association between ACEs and heavy alcohol consumption behavior among adults in rural Uganda. The adverse effects of ACEs were buffered in part by social participation. To prevent or reduce harmful alcohol use behaviors among adults, it is important to address the chronic stress caused by ACEs

Adverse Childhood Experiences · Alcohol · Alcohol consumption · Biology · Economics · Environmental health · Geography · Population · Psychiatry · Social science · Socioeconomics · Sociology · Child Abuse and Related Trauma · Child Abuse and Trauma · Demography · Medicine · Prenatal Substance Exposure Effects · Psychology