Igor Rudan
Datos Biográficos
| ID | 333407 |
|---|---|
| NOMBRE | Igor Rudan |
| NOMBRES | Igor |
| APELLIDO | Rudan |
| FIRMA | RUDAN I |
| AFILIACIONES | University of Edinburgh |
| ORCID | 0000-0001-6993-6884 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 142 |
| TOTAL DE CITAS | 25 |
| TOTAL COMO AUTOR | 142 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1997 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 2 |
Editor's view
Global, regional, and national prevalence of pterygium in 2023
HIV and cardiovascular diseases
BACKGROUND: People living with HIV (PLWH) face a significantly elevated risk of cardiovascular diseases (CVDs). This study aims to quantify temporal trends in HIV-attributable CVD burden at global, regional and national levels using a comparative risk assessment framework. METHODS: We systematically searched PubMed, Embase and MEDLINE for cohort studies from inception to 28 October 2024, assessing HIV infection and CVD risk. Pooled risk ratios (R…
National, regional, and provincial prevalence of age-related macular degeneration in China in 2020
Background: The burden of age-related macular degeneration (AMD) has steadily increased in recent decades. We aimed to estimate the prevalence of AMD, including its subtypes, among individuals aged 40-89 years in China. Methods: We conducted an updated literature search in the CNKI, Wanfang, Chinese Science and Technology Journal Database, PubMed, Embase, and MEDLINE for studies published between 27 June 2016 and 30 July 2024 that reported on the…
Journal of Global Health's GUidelines for Authors on Requesting and DIsclosing changes in Authorship Nominations (Guardian)
We address the growing concern of requests for post-submission and post-acceptance changes in authorship which our editorial team has observed in recent years. We emphasise that authorship order should be agreed upon by all contributors before submission, as all authors are expected to approve the final version of their manuscript and agree on their respective authorship positions. This editorial identifies seven categories of authorship change r…
National, regional and provincial prevalence of carotid atherosclerosis and carotid plaque in Chinese adults
Background: Carotid atherosclerosis (CAS), a major contributor to cardiovascular morbidity in China, exhibits substantial geographic disparities that remain unquantified at the provincial level. We aimed to provide updated national, regional, and provincial prevalence of CAS or carotid plaque (CP) among Chinese adults aged 30-79 years. Methods: We searched CNKI, Wanfang, China Science and Technology Journal Database (VIP), PubMed, Embase, and MED…
Disclosures of conflicts of interest from the editors of the Journal of Global Health – 2026
National, regional and provincial prevalence of peripheral artery disease in Chinese adults in 2023
Background: Peripheral artery disease (PAD), a common atherosclerotic condition characterised by the narrowing or obstruction of peripheral arteries, has become a substantial public health concern in China. However, its prevalence across the country at the provincial level has never been quantified. Through an updated systematic review and modelling study, we aimed to estimate the national, regional, and provincial prevalence of PAD among Chinese…
Journal of Global Health’s Guidelines for Reporting Analyses of Big Data Repositories Open to the Public (GRABDROP)
In recent years, global accessibility to large 'big data' repositories that enable 'open research' - such as the UK Biobank, National Health and Nutrition Examination Survey (NHANES), and Global Burden of Disease (GBD) datasets - has created unprecedented opportunities for researchers worldwide to conduct secondary data analyses. This development is particularly beneficial for early-career researchers in low- and middle-income countries (LMICs), …
Editor’s view
This editorial examines the factors contributing to the success of science, tracing its evolution from fundamental human curiosity to contemporary advancements propelled by technology, data, and artificial intelligence (AI). Beginning with the hypothesis-testing process, it highlights how imaginative individuals throughout history have offered explanations for the natural world, designed experiments, and amassed evidence to confirm or reject thei…
BNT162b2 Covid-19 vaccination uptake, safety, effectiveness, and waning in children and young people aged 5–11 years in Scotland
Background: Few large-scale population studies have examined both safety and vaccine effectiveness (VE) specifically for 5-11-year-olds during the Omicron-dominant period in a setting with low vaccine uptake. The BNT162b2 (Pfizer-BioNTech) vaccine, administered in two doses, has shown strong efficacy against symptomatic and severe COVID-19 in clinical trials involving children and young people (CYP). Accordingly, we examined the uptake, real-worl…
Two decades of the CHNRI method (2006–2025)
Ideometrics
Background: This paper introduces and describes a new integrative scientific approach - ideometrics - building on the 'sense of ideas' and 'value of information' concepts. Ideometrics is the emerging field of generating, evaluating, and prioritising ideas. Methods: Focused on the generation, evaluation and prioritisation of ideas, we identified and then mapped the landscape of methodological approaches that have been used over time, disciplines, …
National, regional, and provincial prevalence of glaucoma in China in 2020
Background: Glaucoma is the leading cause of irreversible blindness worldwide, with a significant disease burden in China. Accurate prevalence estimates are crucial for guiding public health strategies, but large-scale epidemiological investigations remain challenging due to the need for comprehensive ophthalmic assessments. Through a systematic review and modelling approach, we aimed to estimate the national, regional, and provincial prevalence …
The global, regional, and national preventable burden of depression attributable to greenness and inequalities
Background: Growing evidence suggests that exposure to greenness may reduce the burden of depression. Here, we quantified the global, regional, and national preventable burden of depression attributable to greenness and examined the associated socioeconomic inequalities. Methods: We conducted a scenario-based health impact assessment using data from the Global Burden of Disease 2021 study to estimate the preventable burden of depression (measured…
The Covid-19 pandemic in children and young people during 2022–24
The research conducted between 2022 and 2024 has advanced our understanding of COVID-19 in children and young people (CYP), particularly with the emergence of the Omicron variant and its subvariants. The findings have reinforced that, while Omicron infections are often milder compared to earlier variants, the overall seroprevalence of SARS-CoV-2 in children has increased, with notable regional and demographic disparities. COVID-19-related hospita…
Prevalence of osteoporosis and associated factors among Chinese adults
Disclosures of conflicts of interest from the editors of the Journal of Global Health – 2025
WHO global research priorities for traditional, complementary, and integrative (TCI) medicine
Background: Traditional, complementary, and integrative (TCI) medicine is an essential component of health systems worldwide, especially in low- and middle-income countries. Despite its widespread use, existing research on the safety, efficacy, and integration of TCI medicine within conventional healthcare systems is fragmented. This fragmentation highlights the urgent need for a clearly defined global research agenda to guide future studies, sec…
The global and regional prevalence of restless legs syndrome among adults
Disclosures of conflicts of interest from the editors of the Journal of Global Health – 2024
Global, regional, and national burden and quality of care of multiple myeloma, 1990–2019
Background: Multiple myeloma (MM) is the second most common haematologic malignancy, presenting a great disease burden on the general population; however, the quality of care of MM is overlooked. We therefore assessed gains and disparity in quality of care worldwide from 1990 to 2019 based on a novel summary indicator - the quality of care index (QCI) - and examined its potential for improvement. Methods: Using the Global Burden of Disease 2019 d…
Variations in the prevalence of scoliosis by age, sex, geographic region, and subtype among Chinese children
Global incidence and risk factors for glaucoma
Editor’s view
Humans have developed sensory organs for their 'major' senses and specific neuronal receptors for a number of additional senses. Although information from sensors is integrated and processed in the brain, the brain itself has not been proposed as a sensory organ associated with a particular sense - at least not in Western culture or scientific literature. Perception of ideas has many elements of a separate sense, with the brain being a primary se…
Genetic evidence of assortative mating in humans
Genome-wide association study identifies 48 common genetic variants associated with handedness
Handedness has been extensively studied because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank, 23andMe and the International Handedness Consortium, we conducted a genome-wide association meta-analysis of handedness (N = 1,766,671). We found 41 loci associated (P < 5 × 10−8) with left-handedness and 7 associated with ambidexterity. Tissue-enrichmen…
Estimation of inbreeding, kinship, genetic distances, and population structure from surnames
The aim of this study was to estimate inbreeding, kinship, genetic distances, and population structure of the island of Hvar using surnames of the population from 10 villages. Total inbreeding on the island, estimated from the frequency of isonymous marriages, amounted to 0.0228. Total kinship (unreduced variance) of the entire island amounted to 0.0411, a value indicative of very isolated populations with accumulated kinship over time. The analy…
Estimation of inbreeding, kinship, genetic distances, and population structure from surnames
Sets of complementary phenotypic relationships across five isolated populations
The aim of this study is to search for certain repeating phenotypic patterns, i.e. sets of complementary relationships across five isolated populations, which may represent the traces of expression of different genes or gene complexes. The study was conducted among isolates of five island populations of eastern Adriatic, Croatia, and the data were collected between 1979 and 1990. Selected phenotypic characteristics included measures of biological…
Ancestral Kinship and Cancer in Lastovo Island, Croatia
The aim of this study was to compute the average kinship coefficient of cancer cases in an extreme isolate (Lastovo Island, Croatia) and to compare it to the corresponding value for the island's unaffected population. Kinship estimates were obtained by Wright's path method (phi) based on pedigree reconstruction and Lasker's coefficient of relationship by isonymy (Ri) based on surname distribution. A total of 76 cancer cases were recorded on the i…
Genetic Variation at Nine Short Tandem Repeat Loci Among Islanders of the Eastern Adriatic Coast of Croatia
We have analyzed the extent of genetic variation at nine autosomal short tandem repeat loci (D3S1358, VWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, D7S820) among six populations from Croatia: five distributed in the islands of the eastern Adriatic coast and one from the mainland. The purpose is to investigate the usefulness of these loci in detecting regional genetic differentiation in the studied populations. Significant heterogeneity among the…
Setting Priorities in Global Child Health Research Investments
This article provides detailed guidelines for the implementation of systematic method for setting priorities in health research investments that was recently developed by Child Health and Nutrition Research Initiative (CHNRI). The target audience for the proposed method are international agencies, large research funding donors, and national governments and policy-makers. The process has the following steps: (i) selecting the managers of the proce…
Effects of Isolation and Inbreeding on Human Quantitative Traits
Isolation is a known force in evolutionary biology and one of the main factors in speciation. One of the main consequences of severe isolation is reduced mate choice, which results in the occurrence of inbreeding as a result of isolation. We investigated the effects of individual genome-wide heterozygosity measured as the multilocus heterozygosity (MLH) on biochemical markers of hemostasis and inflammation in 1,041 individuals from the island of …
Setting priorities for zinc-related health research to reduce children’s disease burden worldwide
Objective To make the best use of limited resources for supporting health-related research to reduce child mortality, it is necessary to apply a suitable method to rank competing research options. The Child Health and Nutrition Research Initiative (CHNRI) developed a new methodology for setting health research priorities. To broaden experience with this priority-setting technique, we applied the method to rank possible research priorities concern…
Gender differences in spousal household material status estimation
Gender differences in socioeconomic inequalities in mortality are well known.1 However, gender differences in self-reported socioeconomic status in public health surveys has been much less frequently investigated. We aimed to compare the material status estimates provided by men and women in spousal pairs, obtained from the larger genetic epidemiology study in Croatia that was focusing on the families, thus enabling spousal pairs analysis. A tota…
Global, regional, and national causes of child mortality in 2008
Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children
Global, regional, and national causes of child mortality
An estimate of the prevalence of dementia in Africa
BACKGROUND: The burden of non-communicable diseases is growing, particularly in developing countries. The greatest economic burden is due to dementia, the prevalence of which is rising with increasing longevity. In Africa, where the rate of increase of elderly persons is the fastest in the world, dementia is normally dismissed as a part of normal ageing. The lack of awareness means that many patients are suffering undiagnosed. This review aims to…
Optimizing community case management strategies to achieve equitable reduction of childhood pneumonia mortality
BACKGROUND: The aim of this study was to populate the Equitable Impact Sensitive Tool (EQUIST) framework with all necessary data and conduct the first implementation of EQUIST in studying cost-effectiveness of community case management of childhood pneumonia in 5 low- and middle-income countries with relation to equity impact. METHODS: Wealth quintile-specific data were gathered or modelled for all contributory determinants of the EQUIST framewor…
Understanding the determinants of the complex interplay between cost-effectiveness and equitable impact in maternal and child mortality reduction
Understanding the determinants of the complex interplay between cost-effectiveness and equitable impact in maternal and child mortality reduction Background One of the most unexpected outcomes arising from the efforts towards maternal and child mortality reduction is that all too often the objective success has been coupled with increased inequity in the population. The aim of this study is to analyze the determinants of the complex interplay bet…
Setting research priorities to reduce global mortality from preterm birth and low birth weight by 2015
Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza
A cute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008 [1], and the main pathogens responsible for high mortality were Streptococcus pneumoniae, Haemophilus influenzae and respiratory syncytial virus [2-4]. In addition, meningitis was estimated to contribute up to 200 000 dea…
Balancing investments in existing and emerging approaches to address global health priorities
One of the common themes in contemporary global health is finding an optimal balance between investments in existing and emerging approaches to fight global health priorities. Existing interventions have been proven to be effective, but they usually have limitations. Emerging interventions could potentially bring greater gains at a lower cost, but health gains are usually uncertain and take much more time to achieve. There are no simple solutions…
Global burden of childhood pneumonia and diarrhoea
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Interventions to address deaths from childhood pneumonia and diarrhoea equitably
Setting priorities for development of emerging interventions against childhood diarrhoea
An expert panel exercise was conducted to assess feasibility and potential effectiveness of 10 emerging health interventions against childhood diarrhoea. Twelve international experts were invited to take part in a CHNRI priority setting process. This group used 12 different criteria relevant to successful development and implementation of the emerging interventions, nine of which were retained in the final analysis. They showed most collective op…
Reducing mortality from childhood pneumonia and diarrhoea
Pneumonia and diarrhoea have been the leading causes of global child mortality for many decades. The work of Child Health Epidemiology Reference Group (CHERG) has been pivotal in raising awareness that the UN's Millennium Development Goal 4 cannot be achieved without increased focus on preventing and treating the two diseases in low- and middle-income countries. Global Action Plan for Pneumonia (GAPP) and Diarrhoea Global Action Plan (DGAP) group…
MHealth Series
BACKGROUND: We set up a collaboration between researchers in China and the UK that aimed to explore the use of mHealth in China. This is the first paper in a series of papers on a large mHealth project part of this collaboration. This paper included the aims and objectives of the mHealth project, our field site, and the detailed methods of two studies. FIELD SITE: The field site for this mHealth project was Zhao County, which lies 280 km south of…
Ancient human genomes suggest three ancestral populations for present-day Europeans
Medicine (85 obras) · Environmental health (48 obras) · Population (44 obras) · Political science (41 obras) · MEDLINE (39 obras) · Demography (29 obras) · Public health (29 obras) · Global Maternal and Child Health (28 obras) · Biology (25 obras) · Computer Science (24 obras)