Arlene M Davis
Datos Biográficos
| ID | 3582655 |
|---|---|
| NOMBRE | Arlene M Davis |
| NOMBRES | Arlene M |
| APELLIDO | Davis |
| FIRMA | DAVIS A M |
| AFILIACIONES | University of North Carolina at Chapel Hill |
| ORCID | 0000-0001-6486-0446 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 12 |
| TOTAL DE CITAS | 62 |
| TOTAL COMO AUTOR | 12 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1998 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2024 |
| ÍNDICE H | 4 |
Preventive Human Genome Editing and Enhancement
While somatic cell editing to treat disease is widely accepted, the use of human genome editing for “enhancement” remains contested. Scientists and policy‐makers routinely cite the prospect of enhancement as a salient ethical challenge for human genome editing research. If preventive genome editing projects are perceived as pursuing human enhancement, they could face heightened barriers to scientific, public, and regulatory approval. This article…
Reconsidering scarce drug rationing
Hospital systems commonly face the challenge of determining just ways to allocate scarce drugs during national shortages. There is no standardised approach of how this should be instituted, but principles of distributive justice are commonly used so that patients who are most likely to benefit from the drug receive it. As a result, clinical indications, in which the evidence for the drug is assumed to be established, are often prioritised over re…
An Evaluation of the Middle East Research Training Initiative Tool in Assessing Effective Functioning of Research Ethics Committees
The effective functioning of a research ethics committee (REC) can be evaluated using self-assessment tools. The Middle East Research Ethics Training Initiative (MERETI) tool can be used by one member, typically the Chair, to score an REC. The consistency of these scores across several members of an REC has never been evaluated. This study examined whether results would be consistent irrespective of who conducts the assessment. One REC's effectiv…
The Meaning of Genetic Research Results
In the debate about whether to return individual genetic results to research participants, consideration of the nature of results has taken precedence over contextual factors associated with different study designs and populations. We conducted in-depth interviews with 24 individuals who participated in a genotype-driven study of cystic fibrosis: 9 of the individuals had cystic fibrosis, 15 had participated as healthy volunteers, and all had gene…
Parents' Online Portrayals of Pediatric Treatment and Research Options
PARENTS OF SERIOUSLY ILL CHILDREN FACE difficult decisions when standard therapies are limited or ineffective. In their search for information, they may turn to websites created by other parents facing similar experiences. We conducted a qualitative content analysis of 21 websites created by families with children affected by cancer or genetic disease, two serious conditions with a range of treatment and clinical trial options. Our research quest…
A place for genetic uncertainty
Therapeutic misconception in early phase gene transfer trials
The many meanings of care in clinical research
The conduct of clinical research often involves two distinguishable sets of relationships: the researcher-subject relationship, and the clinician-patient relationship. Some scholars argue that being a patient in a clinical care setting and a subject in a research study are so different that anything that would promote in subjects the view that they are in clinician-patient relationships is exploitative and deceptive. This paper presents findings …
Consent Forms and the Therapeutic Misconception
Nancy M. P. King, Gail E. Henderson, Larry R. Churchill, Arlene M. Davis, Sara Chandros Hull, Daniel K. Nelson, P. Christy Parham-Vetter, Barbra Bluestone Rothschild, Michele M. Easter, Benjamin S. Wilfond, Consent Forms and the Therapeutic Misconception: The Example of Gene Transfer Research, IRB: Ethics & Human Research, Vol. 27, No. 1 (Jan. - Feb., 2005), pp. 1-8
Confidentiality
Assessing Benefits in Clinical Research
Larry R. Churchill, Daniel K. Nelson, Gail E. Henderson, Nancy M. P. King, Arlene M. Davis, Erin Leahey, Benjamin S. Wilfond, Assessing Benefits in Clinical Research: Why Diversity in Benefit Assessment Can Be Risky, IRB: Ethics & Human Research, Vol. 25, No. 3 (May - Jun., 2003), pp. 1-8
Exception from Informed Consent for Emergency Research
A place for genetic uncertainty
The many meanings of care in clinical research
The conduct of clinical research often involves two distinguishable sets of relationships: the researcher-subject relationship, and the clinician-patient relationship. Some scholars argue that being a patient in a clinical care setting and a subject in a research study are so different that anything that would promote in subjects the view that they are in clinician-patient relationships is exploitative and deceptive. This paper presents findings …
Therapeutic misconception in early phase gene transfer trials
The Meaning of Genetic Research Results
In the debate about whether to return individual genetic results to research participants, consideration of the nature of results has taken precedence over contextual factors associated with different study designs and populations. We conducted in-depth interviews with 24 individuals who participated in a genotype-driven study of cystic fibrosis: 9 of the individuals had cystic fibrosis, 15 had participated as healthy volunteers, and all had gene…
Parents' Online Portrayals of Pediatric Treatment and Research Options
PARENTS OF SERIOUSLY ILL CHILDREN FACE difficult decisions when standard therapies are limited or ineffective. In their search for information, they may turn to websites created by other parents facing similar experiences. We conducted a qualitative content analysis of 21 websites created by families with children affected by cancer or genetic disease, two serious conditions with a range of treatment and clinical trial options. Our research quest…
An Evaluation of the Middle East Research Training Initiative Tool in Assessing Effective Functioning of Research Ethics Committees
The effective functioning of a research ethics committee (REC) can be evaluated using self-assessment tools. The Middle East Research Ethics Training Initiative (MERETI) tool can be used by one member, typically the Chair, to score an REC. The consistency of these scores across several members of an REC has never been evaluated. This study examined whether results would be consistent irrespective of who conducts the assessment. One REC's effectiv…
Exception from Informed Consent for Emergency Research
Assessing Benefits in Clinical Research
Larry R. Churchill, Daniel K. Nelson, Gail E. Henderson, Nancy M. P. King, Arlene M. Davis, Erin Leahey, Benjamin S. Wilfond, Assessing Benefits in Clinical Research: Why Diversity in Benefit Assessment Can Be Risky, IRB: Ethics & Human Research, Vol. 25, No. 3 (May - Jun., 2003), pp. 1-8
Confidentiality
Consent Forms and the Therapeutic Misconception
Nancy M. P. King, Gail E. Henderson, Larry R. Churchill, Arlene M. Davis, Sara Chandros Hull, Daniel K. Nelson, P. Christy Parham-Vetter, Barbra Bluestone Rothschild, Michele M. Easter, Benjamin S. Wilfond, Consent Forms and the Therapeutic Misconception: The Example of Gene Transfer Research, IRB: Ethics & Human Research, Vol. 27, No. 1 (Jan. - Feb., 2005), pp. 1-8
Therapeutic misconception in early phase gene transfer trials
The many meanings of care in clinical research
The conduct of clinical research often involves two distinguishable sets of relationships: the researcher-subject relationship, and the clinician-patient relationship. Some scholars argue that being a patient in a clinical care setting and a subject in a research study are so different that anything that would promote in subjects the view that they are in clinician-patient relationships is exploitative and deceptive. This paper presents findings …
A place for genetic uncertainty
Parents' Online Portrayals of Pediatric Treatment and Research Options
PARENTS OF SERIOUSLY ILL CHILDREN FACE difficult decisions when standard therapies are limited or ineffective. In their search for information, they may turn to websites created by other parents facing similar experiences. We conducted a qualitative content analysis of 21 websites created by families with children affected by cancer or genetic disease, two serious conditions with a range of treatment and clinical trial options. Our research quest…
The Meaning of Genetic Research Results
In the debate about whether to return individual genetic results to research participants, consideration of the nature of results has taken precedence over contextual factors associated with different study designs and populations. We conducted in-depth interviews with 24 individuals who participated in a genotype-driven study of cystic fibrosis: 9 of the individuals had cystic fibrosis, 15 had participated as healthy volunteers, and all had gene…
An Evaluation of the Middle East Research Training Initiative Tool in Assessing Effective Functioning of Research Ethics Committees
The effective functioning of a research ethics committee (REC) can be evaluated using self-assessment tools. The Middle East Research Ethics Training Initiative (MERETI) tool can be used by one member, typically the Chair, to score an REC. The consistency of these scores across several members of an REC has never been evaluated. This study examined whether results would be consistent irrespective of who conducts the assessment. One REC's effectiv…
Reconsidering scarce drug rationing
Hospital systems commonly face the challenge of determining just ways to allocate scarce drugs during national shortages. There is no standardised approach of how this should be instituted, but principles of distributive justice are commonly used so that patients who are most likely to benefit from the drug receive it. As a result, clinical indications, in which the evidence for the drug is assumed to be established, are often prioritised over re…
Preventive Human Genome Editing and Enhancement
While somatic cell editing to treat disease is widely accepted, the use of human genome editing for “enhancement” remains contested. Scientists and policy‐makers routinely cite the prospect of enhancement as a salient ethical challenge for human genome editing research. If preventive genome editing projects are perceived as pursuing human enhancement, they could face heightened barriers to scientific, public, and regulatory approval. This article…
Psychology (9 obras) · Medicine (8 obras) · Ethics in Clinical Research (5 obras) · Political science (5 obras) · Biology (4 obras) · Genetics (4 obras) · Pathology (4 obras) · Alternative medicine (3 obras) · Biomedical Ethics and Regulation (3 obras) · Clinical trial (3 obras)