Michael Morrison
Datos Biográficos
| ID | 3603741 |
|---|---|
| NOMBRE | Michael Morrison |
| NOMBRES | Michael |
| APELLIDO | Morrison |
| FIRMA | MORRISON M |
| AFILIACIONES | University of Oxford |
| ORCID | 0000-0001-6870-6673 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 25 |
| TOTAL DE CITAS | 46 |
| TOTAL COMO AUTOR | 25 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2003 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 3 |
Ethics Review of AI research
The recent advancements in artificial intelligence (AI), and data science more broadly, have led to a proliferation of new methods and tools, such as machine learning (ML), that are used in all kinds of scientific research, from biomedical research through to environmental and education research. Research ethics review bodies are increasingly required to review AI research protocols that cover these different fields of enquiry. Questions have bee…
Producing Value or Responding to Valuation
This paper examines how small and medium-sized enterprises (SMEs) commercialise contemporary biomodifying technologies, focusing on induced pluripotent stem cells (iPSC) and 3D bioprinting. Drawing on qualitative interviews and desk-based mapping of the commercial landscapes surrounding these technologies, we analyse what is being commercialised, in what forms, and how firms justify their strategic choices. Combining insights from STS debates on …
Readiness’ as a model to explain the differing adoption rates of gene editing technology in the laboratory and industrial manufacturing sites
Advanced therapies utilise cells or tissues of genetic modification for therapeutic effect. ‘Institutional Readiness’ (IR) is a sociologically-informed model of technology adoption developed to assess the degree of ‘fit’ between advanced therapies and a clinical environment. In its current formulation, IR assesses ‘readiness’ of hospital sites to deliver finished (i.e. ready to use) advanced therapy products, using eight orthogonal categories. Th…
Participation in SoHO and ATMP public consultations
In the European Union (EU), the recent adoption of the Substances of Human Origin (SoHO) Regulation in June 2024 brings into force new harmonised rules for human cells, tissues and blood. This legislation interacts with the pre-existing Advanced Therapy Medicinal Products (ATMP) Regulation. This paper looks at the recent EU public consultations on the proposed SoHO Regulation and compares them with the prior consultations on the ATMP Regulation g…
The Hearth as the Heart of the Family
This chapter explores the foodways and daily lives of Aboriginal people at the former Weipa Mission, North-Eastern Australia. Christian Missions were a vital part of the colonising repertoire of the British in Australia, as elsewhere, but despite the hardships and traumatic histories these places represent, they are frequently of very high cultural significance to First Nations’ People today. As in many colonial settings, documentary records are …
Making translational value
Biomedical translational researchers aim to develop knowledge and techniques arising from research in the life sciences into clinical applications. Using the examples of induced pluripotent stem cells (iPSC) and gene editing, this paper examines how translational researchers identify and justify which particular conditions or patient populations make ‘good targets’ for translational research with particular technologies. Drawing on empirical data…
Making bio-objects mobile
Research using free text data in medical records could benefit from dynamic consent and other tools for responsible governance
As the capacity to generate, store, aggregate and combine ever greater volumes and types of data about individuals, behaviours and interactions continues to expand apace, so too does the challenge of ensuring suitable and appropriate governance of that data. In broad terms, the challenge is simple; how to ensure the (public) benefits of data, such as improvements in service delivery or individual and collective well-being, while avoiding harms su…
Genome editing
Genome editing enables very accurate alterations to DNA. It promises profound and potentially disruptive changes in healthcare, agriculture, industry, and the environment. This paper presents a multidisciplinary analysis of the contemporary development of genome editing and the tension between continuity and change. It draws on the idea that actors involved in innovation are guided by “sociotechnical regimes” composed of practices, institutions, …
Governance of research consortia
Responsible Research and Innovation (‘RRI’) is a cross-cutting priority for scientific research in the European Union and beyond. This paper considers whether the way such research is organised and delivered lends itself to the aims of RRI. We focus particularly on international consortia, which have emerged as a common model to organise large-scale, multi-disciplinary research in contemporary biomedical science. Typically, these consortia operat…
Valuing height
This paper proposes a 'valuographic' approach to diagnosis, exploring how values and valuation practices are implicated in the contested diagnostic category of idiopathic short stature (ISS). ISS describes children who are 'abnormally' short but do not have any other detectable pathology. In the USA growth-promoting hormone therapy has been approved for ISS children, since 2003. However, no other jurisdiction has approved this treatment and the v…
Making Cells Worthwhile
The StemBANCC consortium was a large European consortium bringing together scientists from academic institutions and the pharmaceutical industry. The aim of the consortium was to produce 1500 induced pluripotent stem cell (iPSC) lines from participants with a variety of common, complex diseases. These cell lines were intended to help develop iPSC as tools for screening small molecule drug candidates and modelling human diseases in vitro. The scal…
Regulating human stem cell research and therapy in low- and middle-income countries
Many “rising powers” such as India, China, Argentina, Singapore, and Brazil are investing in stem cell technology, joining the traditional leaders in the field, such as the UK, Germany, USA, and Japan. Malaysia is also entering this sector because of the potential medical and economic benefits that the use of stem cell technologies could provide. Like other countries, Malaysia faces the challenge of how to encourage scientific progress and innova…
Infrastructural expectations
This paper investigates the recent emergence of several major projects to bank and distribute large numbers of human induced pluripotent stem cells (hiPSCs) for translational research. The conceptual framework of the sociology of expectations is applied to interrogate the promise underpinning these developments. An analytic distinction is made between expectations associated with the field of hiPSC research more broadly and those specifically inv…
A good collaboration is based on unique contributions from each side”
The rise of 'big biology' is bringing academic and industrial scientists together in large consortia to address translational challenges in the life sciences. In order to assess the impact of this change, this paper examines the existing norms and styles of collaboration in one high profile translational domain; stem cell research. Data is drawn from qualitative interviews with academic and industry scientists working in a large European stem cel…
The Dark Forest
The third part, a rush of unchaptered narrative, takes place during the German occupation of Denmark and focuses on Kaj, now a methamphetamine-driven coordinator of samizdat news-sheets. Ib, too, has joined the Resistance but is a shadowy figure , close to cardiac collapse. The brothers both die in 1944: Ib in a hospital respirator and Kaj in Gestapo headquarters. He jumps to his death after having been tortured into submission by a German office…
Dynamic consent
Biomedical research is being transformed through the application of information technologies that allow ever greater amounts of data to be shared on an unprecedented scale. However, the methods for involving participants have not kept pace with changes in research capability. In an era when information is shared digitally at the global level, mechanisms of informed consent remain static, paper-based and organised around national boundaries and le…
STS and Enhancement Technologies – A Programme for Future Research
The concept of human technological enhancement originated as a tool for the moral classification of technologies, but has since spilled over from ethical debates to become a site for prospective technology development as part of a ‘converging technologies’ agenda. To date, enhancement and the technologies labelled as ‘enhancing’ have been underserved by STS research. While case studies do exist, there has been a dearth of co-ordinated investigati…
Growth hormone, enhancement and the pharmaceuticalisation of short stature
Chronological trends in late Holocene shell mound construction across northern Australia
Shell mound sites dating from the mid-Holocene and containing very large numbers of the estuarine bivalve Anadara granosa are found across northern Australia. It has recently been proposed that the economic, social and cultural practices linked to their formation ceased some 500–700 years ago across northern Australia as a result of environmental changes leading to the substantially reduced availability of A. granosa. This has been used in suppor…
The evolution of withdrawal
The right to withdraw from research, along with the necessity of adequately informed consent, is at the heart of the post-Nuremburg code of ethical safeguards in biomedical research on human participants. As biomedical research moves away from direct interventional studies towards research using networks of linked human tissue samples and data, however, questions arise about what withdrawal can and should mean in these new contexts. Some of the m…
Me medicine vs. we medicine
Promissory futures and possible pasts
Exploring the Role of Dedicated Online Biotechnology News Providers in the Innovation Economy
In this article, the authors examine the role of dedicated online biotechnology news providers in disseminating and shaping stories of technological promise within the bioeconomy. In this field, communication of future-orientated claims is closely linked to a firm's ability to attract speculative investment and so dedicated biotech news services play an important role in facilitating this interaction between technology producers and investors. Us…
Old boundaries and new horizons
This paper develops an alternative interpretation of shell mound phenomena at Albatross Bay, near Weipa on the west coast of Cape York Peninsula. Past researchers have interpreted these distinct mounded middens as functional edifices, constructed to enable small family groups to camp closer to resources during the late wet season. Here I propose that the mounds at Weipa were associated with relatively large groups of people intensively exploiting…
Old boundaries and new horizons
This paper develops an alternative interpretation of shell mound phenomena at Albatross Bay, near Weipa on the west coast of Cape York Peninsula. Past researchers have interpreted these distinct mounded middens as functional edifices, constructed to enable small family groups to camp closer to resources during the late wet season. Here I propose that the mounds at Weipa were associated with relatively large groups of people intensively exploiting…
Growth hormone, enhancement and the pharmaceuticalisation of short stature
Chronological trends in late Holocene shell mound construction across northern Australia
Shell mound sites dating from the mid-Holocene and containing very large numbers of the estuarine bivalve Anadara granosa are found across northern Australia. It has recently been proposed that the economic, social and cultural practices linked to their formation ceased some 500–700 years ago across northern Australia as a result of environmental changes leading to the substantially reduced availability of A. granosa. This has been used in suppor…
A good collaboration is based on unique contributions from each side”
The rise of 'big biology' is bringing academic and industrial scientists together in large consortia to address translational challenges in the life sciences. In order to assess the impact of this change, this paper examines the existing norms and styles of collaboration in one high profile translational domain; stem cell research. Data is drawn from qualitative interviews with academic and industry scientists working in a large European stem cel…
Valuing height
This paper proposes a 'valuographic' approach to diagnosis, exploring how values and valuation practices are implicated in the contested diagnostic category of idiopathic short stature (ISS). ISS describes children who are 'abnormally' short but do not have any other detectable pathology. In the USA growth-promoting hormone therapy has been approved for ISS children, since 2003. However, no other jurisdiction has approved this treatment and the v…
Making Cells Worthwhile
The StemBANCC consortium was a large European consortium bringing together scientists from academic institutions and the pharmaceutical industry. The aim of the consortium was to produce 1500 induced pluripotent stem cell (iPSC) lines from participants with a variety of common, complex diseases. These cell lines were intended to help develop iPSC as tools for screening small molecule drug candidates and modelling human diseases in vitro. The scal…
The evolution of withdrawal
The right to withdraw from research, along with the necessity of adequately informed consent, is at the heart of the post-Nuremburg code of ethical safeguards in biomedical research on human participants. As biomedical research moves away from direct interventional studies towards research using networks of linked human tissue samples and data, however, questions arise about what withdrawal can and should mean in these new contexts. Some of the m…
Old boundaries and new horizons
This paper develops an alternative interpretation of shell mound phenomena at Albatross Bay, near Weipa on the west coast of Cape York Peninsula. Past researchers have interpreted these distinct mounded middens as functional edifices, constructed to enable small family groups to camp closer to resources during the late wet season. Here I propose that the mounds at Weipa were associated with relatively large groups of people intensively exploiting…
Promissory futures and possible pasts
Exploring the Role of Dedicated Online Biotechnology News Providers in the Innovation Economy
In this article, the authors examine the role of dedicated online biotechnology news providers in disseminating and shaping stories of technological promise within the bioeconomy. In this field, communication of future-orientated claims is closely linked to a firm's ability to attract speculative investment and so dedicated biotech news services play an important role in facilitating this interaction between technology producers and investors. Us…
Me medicine vs. we medicine
Chronological trends in late Holocene shell mound construction across northern Australia
Shell mound sites dating from the mid-Holocene and containing very large numbers of the estuarine bivalve Anadara granosa are found across northern Australia. It has recently been proposed that the economic, social and cultural practices linked to their formation ceased some 500–700 years ago across northern Australia as a result of environmental changes leading to the substantially reduced availability of A. granosa. This has been used in suppor…
The evolution of withdrawal
The right to withdraw from research, along with the necessity of adequately informed consent, is at the heart of the post-Nuremburg code of ethical safeguards in biomedical research on human participants. As biomedical research moves away from direct interventional studies towards research using networks of linked human tissue samples and data, however, questions arise about what withdrawal can and should mean in these new contexts. Some of the m…
Dynamic consent
Biomedical research is being transformed through the application of information technologies that allow ever greater amounts of data to be shared on an unprecedented scale. However, the methods for involving participants have not kept pace with changes in research capability. In an era when information is shared digitally at the global level, mechanisms of informed consent remain static, paper-based and organised around national boundaries and le…
STS and Enhancement Technologies – A Programme for Future Research
The concept of human technological enhancement originated as a tool for the moral classification of technologies, but has since spilled over from ethical debates to become a site for prospective technology development as part of a ‘converging technologies’ agenda. To date, enhancement and the technologies labelled as ‘enhancing’ have been underserved by STS research. While case studies do exist, there has been a dearth of co-ordinated investigati…
Growth hormone, enhancement and the pharmaceuticalisation of short stature
The Dark Forest
The third part, a rush of unchaptered narrative, takes place during the German occupation of Denmark and focuses on Kaj, now a methamphetamine-driven coordinator of samizdat news-sheets. Ib, too, has joined the Resistance but is a shadowy figure , close to cardiac collapse. The brothers both die in 1944: Ib in a hospital respirator and Kaj in Gestapo headquarters. He jumps to his death after having been tortured into submission by a German office…
Regulating human stem cell research and therapy in low- and middle-income countries
Many “rising powers” such as India, China, Argentina, Singapore, and Brazil are investing in stem cell technology, joining the traditional leaders in the field, such as the UK, Germany, USA, and Japan. Malaysia is also entering this sector because of the potential medical and economic benefits that the use of stem cell technologies could provide. Like other countries, Malaysia faces the challenge of how to encourage scientific progress and innova…
Infrastructural expectations
This paper investigates the recent emergence of several major projects to bank and distribute large numbers of human induced pluripotent stem cells (hiPSCs) for translational research. The conceptual framework of the sociology of expectations is applied to interrogate the promise underpinning these developments. An analytic distinction is made between expectations associated with the field of hiPSC research more broadly and those specifically inv…
A good collaboration is based on unique contributions from each side”
The rise of 'big biology' is bringing academic and industrial scientists together in large consortia to address translational challenges in the life sciences. In order to assess the impact of this change, this paper examines the existing norms and styles of collaboration in one high profile translational domain; stem cell research. Data is drawn from qualitative interviews with academic and industry scientists working in a large European stem cel…
Making Cells Worthwhile
The StemBANCC consortium was a large European consortium bringing together scientists from academic institutions and the pharmaceutical industry. The aim of the consortium was to produce 1500 induced pluripotent stem cell (iPSC) lines from participants with a variety of common, complex diseases. These cell lines were intended to help develop iPSC as tools for screening small molecule drug candidates and modelling human diseases in vitro. The scal…
Valuing height
This paper proposes a 'valuographic' approach to diagnosis, exploring how values and valuation practices are implicated in the contested diagnostic category of idiopathic short stature (ISS). ISS describes children who are 'abnormally' short but do not have any other detectable pathology. In the USA growth-promoting hormone therapy has been approved for ISS children, since 2003. However, no other jurisdiction has approved this treatment and the v…
Research using free text data in medical records could benefit from dynamic consent and other tools for responsible governance
As the capacity to generate, store, aggregate and combine ever greater volumes and types of data about individuals, behaviours and interactions continues to expand apace, so too does the challenge of ensuring suitable and appropriate governance of that data. In broad terms, the challenge is simple; how to ensure the (public) benefits of data, such as improvements in service delivery or individual and collective well-being, while avoiding harms su…
Genome editing
Genome editing enables very accurate alterations to DNA. It promises profound and potentially disruptive changes in healthcare, agriculture, industry, and the environment. This paper presents a multidisciplinary analysis of the contemporary development of genome editing and the tension between continuity and change. It draws on the idea that actors involved in innovation are guided by “sociotechnical regimes” composed of practices, institutions, …
Governance of research consortia
Responsible Research and Innovation (‘RRI’) is a cross-cutting priority for scientific research in the European Union and beyond. This paper considers whether the way such research is organised and delivered lends itself to the aims of RRI. We focus particularly on international consortia, which have emerged as a common model to organise large-scale, multi-disciplinary research in contemporary biomedical science. Typically, these consortia operat…
Making translational value
Biomedical translational researchers aim to develop knowledge and techniques arising from research in the life sciences into clinical applications. Using the examples of induced pluripotent stem cells (iPSC) and gene editing, this paper examines how translational researchers identify and justify which particular conditions or patient populations make ‘good targets’ for translational research with particular technologies. Drawing on empirical data…
Making bio-objects mobile
The Hearth as the Heart of the Family
This chapter explores the foodways and daily lives of Aboriginal people at the former Weipa Mission, North-Eastern Australia. Christian Missions were a vital part of the colonising repertoire of the British in Australia, as elsewhere, but despite the hardships and traumatic histories these places represent, they are frequently of very high cultural significance to First Nations’ People today. As in many colonial settings, documentary records are …
Participation in SoHO and ATMP public consultations
In the European Union (EU), the recent adoption of the Substances of Human Origin (SoHO) Regulation in June 2024 brings into force new harmonised rules for human cells, tissues and blood. This legislation interacts with the pre-existing Advanced Therapy Medicinal Products (ATMP) Regulation. This paper looks at the recent EU public consultations on the proposed SoHO Regulation and compares them with the prior consultations on the ATMP Regulation g…
Ethics Review of AI research
The recent advancements in artificial intelligence (AI), and data science more broadly, have led to a proliferation of new methods and tools, such as machine learning (ML), that are used in all kinds of scientific research, from biomedical research through to environmental and education research. Research ethics review bodies are increasingly required to review AI research protocols that cover these different fields of enquiry. Questions have bee…
Producing Value or Responding to Valuation
This paper examines how small and medium-sized enterprises (SMEs) commercialise contemporary biomodifying technologies, focusing on induced pluripotent stem cells (iPSC) and 3D bioprinting. Drawing on qualitative interviews and desk-based mapping of the commercial landscapes surrounding these technologies, we analyse what is being commercialised, in what forms, and how firms justify their strategic choices. Combining insights from STS debates on …
Readiness’ as a model to explain the differing adoption rates of gene editing technology in the laboratory and industrial manufacturing sites
Advanced therapies utilise cells or tissues of genetic modification for therapeutic effect. ‘Institutional Readiness’ (IR) is a sociologically-informed model of technology adoption developed to assess the degree of ‘fit’ between advanced therapies and a clinical environment. In its current formulation, IR assesses ‘readiness’ of hospital sites to deliver finished (i.e. ready to use) advanced therapy products, using eight orthogonal categories. Th…
Political science (12 obras) · Biomedical Ethics and Regulation (11 obras) · Sociology (11 obras) · Biology (10 obras) · Computer Science (10 obras) · Business (8 obras) · Engineering (8 obras) · Medicine (8 obras) · Law (7 obras) · Engineering ethics (6 obras)