Effects of Cognitive Training on Alzheimer’s Disease and Related Dementias

The Moderating Role of Social Determinants of Health

Datos Bibliográficos

ID12798707
AutoresGeorge W Rebok (0000-0002-5371-8767, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, autor de correspondencia), Andrew Gellert (TIAA Institute, New York, NY, USA), Norma B Coe (0000-0003-1228-0938, University of Pennsylvania), Wesley R Browning (0000-0002-7529-6120, University of Alabama at Birmingham), Gail Wallace (0000-0002-4974-5885, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA), Jeanine M Parisi (0000-0002-0877-6845, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA), Adrienne T Aiken‐Morgan (0000-0001-7069-9601, Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA), Michael Crowe (0000-0001-7736-4441, University of Alabama at Birmingham), Karlene Ball (0000-0003-1811-9870, University of Alabama at Birmingham), Roland J Thorpe (0000-0002-4448-4997, Johns Hopkins University), Michael Marsiske (0000-0001-5973-2116, University of Florida), Laura B Zahodne (0000-0002-5763-4501, University of Michigan), Cynthia Felix (0000-0002-4283-4498, University of Pittsburgh), Sherry L Willis (0000-0002-1404-179X, University of Washington)
Año2023
Volumen35
Número9_suppl
Páginas40S-50S
Fecha de publicación2023-10-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Aging and Health (JOURNAL)
Identificadores de la revistaISSN: 1552-6887 • E-ISSN: 0898-2643
EditorialSAGE Publishing (PUBLISHER • US)
DOI10.1177/08982643231203755
PMID37994850
OpenAlexW4388950414
IdiomaEN
Citas recibidas2
Referencias citadas36

Objective: We examined whether social determinants of health (SDoH) are associated with Alzheimer's disease and related dementias (ADRD) risk and the effects of cognitive training over a 20-year follow-up period. Methods: Data were obtained from 1605 participants in ACTIVE. SDoH measures were created using baseline data at the individual and neighborhood level. Incident ADRD was defined using administrative claims data (1999-2019). Cause-specific hazard models estimated associations between SDoH and claims-based diagnosed ADRD. Results: Higher scores on neighborhood and built environment were associated with lower ADRD risk. Trained participants obtained a greater degree of protection from ADRD when they had higher scores for SDoH domains associated with health care and education access. However, there were fewer significant SDoH moderation effects on cognitive training than expected. Discussion: Future work should continue to explore culturally tailored cognitive training interventions to reduce ADRD risk associated with SDoH that disproportionately affects racially diverse aging populations

Cognition · Dementia · Disease · Moderation · Psychiatry · Psychological intervention · Public health · Social determinants of health · Clinical Psychology · Dementia and Cognitive Impairment Research · Health disparities and outcomes · Medicine · Migration, Health and Trauma · Nursing · Psychology · Social Psychology · Gerontology