Dietary intake and body composition in HIV-positive and -negative South African women

Datos Bibliográficos

ID15090331
AutoresStephanie V Wrottesley (0000-0002-5419-2920, University of the Witwatersrand), Lisa K Micklesfield (0000-0002-4994-0779, University of the Witwatersrand), Matthew M Hamill (0000-0002-1277-819X, University of the Witwatersrand), Gail R Goldberg, Gail Goldberg (MRC Human Nutrition Research), Ann Prentice (0000-0003-0254-6659, MRC Human Nutrition Research), John M Pettifor (0000-0003-1155-0334, University of the Witwatersrand), Shane A Norri (0000-0001-7124-3788, University of the Witwatersrand), Shane A Norris, Alison Feeley (0000-0002-2526-6097, University of the Witwatersrand, autor de correspondencia), Alison B Feeley
Año2014
Volumen17
Número7
Páginas1603-1613
Fecha de publicación2014-07-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaPublic Health Nutrition (JOURNAL)
Identificadores de la revistaISSN: 1368-9800 • E-ISSN: 1475-2727
EditorialCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980013001808
PMID23835214
PMCIDPMC4045640
OpenAlexW2077923988
IdiomaEN
Citas recibidas9
Referencias citadas24

Objective The present paper examines dietary intake and body composition in antiretroviral (ARV)-naïve HIV-positive compared with HIV-negative South African women, as well as the impact of disease severity on these variables. Design Baseline data from a longitudinal study assessing bone health in HIV-negative and HIV-positive premenopausal South African women over 18 years of age were used. Anthropometry and body composition, measured by dual energy X-ray absorptiometry, were analysed together with dietary intake data assessed using an interviewer-based quantitative FFQ. Setting Soweto, Johannesburg, South Africa. Subjects Black, urban South African women were divided into three groups: (i) HIV-negative (HIV − ; n 98); (ii) HIV-positive with preserved CD4 counts (HIV + non-ARV; n 74); and (iii) HIV-positive with low CD4 counts and due to start ARV treatment (HIV + pre-ARV; n 75). Results The prevalence of overweight and obesity was high in this population (59 %). The HIV + pre-ARV group was lighter and had a lower BMI than the other two groups (all P + pre-ARV women also had lower fat and lean masses and percentage body fat than their HIV − and HIV + non-ARV counterparts. After adjustment, there were no differences in macronutrient intakes across study groups; however, fat and sugar intakes were high and consumption of predominantly refined food items was common overall. Conclusion HIV-associated immunosuppression may be a key determinant of body composition in HIV-positive women. However, in populations with high obesity prevalence, these differences become evident only at advanced stages of infection

Anthropometry · Environmental health · Human immunodeficiency virus (HIV · Obesity · Overweight · Population · Demography · Diet and metabolism studies · HIV-related health complications and treatments · Medicine · Immunology · Internal Medicine