Effects of aripiprazole on prolactin levels and differences in effectiveness in patients with schizophrenia
A post-hoc analysis of the real-world data of a multicenter study
Datos Bibliográficos
| ID | 15526348 |
|---|---|
| Autores | Qian Li (0000-0003-1286-8539, Peking University), Yun‐Ai Su (0000-0001-8445-9633, Peking University), Yun-Ai Su, Xuemei Liao (0000-0002-6899-7914, Peking University), Maosheng Fang, Jianliang Gao (0000-0002-9363-9908, The Fourth People's Hospital), Jia Xu (0000-0003-1238-1317), Mingjun Duan (0000-0001-9511-6812, The Fourth People's Hospital), Haiying Yu (0000-0002-7648-7930, Chinese People's Liberation Army), Yang Yang (0000-0002-3705-7612, Beijing Anding Hospital), Zhiyu Chen (0000-0001-7937-642X, Hangzhou Seventh Peoples Hospital), Jintong Liu (0000-0002-1100-0378, Shandong Mental Health Center), Shaoxiao Yan (Beijing HuiLongGuan Hospital), Peifen Yao, Pei-Fen Yao (Shanghai Mental Health Center), Shuying Li (0000-0001-6706-4904, First Affiliated Hospital of Zhengzhou University), Changhong Wang (0000-0001-7578-4856, Henan Psychiatric Hospital), Bin Wu (0000-0002-7568-1993, Xian Mental Health Center), Congpei Zhang, Tian-Mei Si (0000-0001-9823-2720, Peking University, autor de correspondencia), Tianmei Si |
| Año | 2024 |
| Volumen | 15 |
| Páginas | 1383173-1383173 |
| Fecha de publicación | 2024-08-29 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | Frontiers in Psychiatry (JOURNAL) |
| Identificadores de la revista | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Editorial | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2024.1383173 |
| PMID | 39267697 |
| OpenAlex | W4402021009 |
| Idioma | EN |
| Referencias citadas | 31 |
In this real-world study, for patients with acute schizophrenia, aripiprazole was effective in lowering the proportion of patients with abnormal prolactin levels, while it had no significant effect on patients with normal baseline prolactin. After adjusting for factors such as sex, age, prior antipsychotic drugs use history and disease severity, effectiveness and safety of aripiprazole in patients with normal baseline prolactin was significantly better than that in patients with elevated baseline prolactin
Antipsychotic · Aripiprazole · Hormone · Post-hoc analysis · Prolactin · Psychiatry · Schizophrenia (object-oriented programming · Genetic Associations and Epidemiology · Medicine · Pituitary Gland Disorders and Treatments · Psychology · Schizophrenia research and treatment · Endocrinology · Internal Medicine
| Velocidad de citación | historical |
|---|---|
| Altamente citado | No |