Population-level seropositivity trend for Sars-Cov-2 in Rio Grande do Sul, Brazil

Datos Bibliográficos

ID16780667
AutoresAluísio J D Barros (0000-0002-2022-8729, Universidade Federal de Pelotas), Cesar G Victora (0000-0002-2465-2180, Universidade Federal de Pelotas), Ana M B Menezes (0000-0002-2996-9427, Universidade Federal de Pelotas), Bernardo L Horta (0000-0001-9843-412X, Universidade Federal de Pelotas), Fernando C Barros (0000-0001-5973-1746, Universidade Federal de Pelotas), Fernando Pires Hartwig (0000-0003-3729-0710, Universidade Federal de Pelotas), Gabriel Victora (0000-0001-8807-348X, Rockefeller University), Luis Paulo Vidaletti Ruas (0000-0002-2840-6841, Universidade Federal de Pelotas), Mariela Felisbino Da Silveira (0000-0002-2861-7139, Universidade Federal de Pelotas), Marilia Arndt Mesenburg (0000-0001-9598-4193, Universidade Federal de Ciências da Saúde de Porto Alegre), Nadège Jacques (0000-0002-2204-3330, Universidade Federal de Pelotas), Cláudio José Struchiner (0000-0003-2114-847X, Fundação Getulio Vargas), Flávia Roberta Brust (0000-0002-2365-6403, Universidade Federal de Ciências da Saúde de Porto Alegre), Marinel M Dall’agnol (0000-0001-5783-7061, Universidade Federal de Santa Maria), Ana Paula Longaray Delamare (0000-0001-9638-5483, Universidade de Caxias do Sul), Carlos Henrique R François (0000-0002-5379-3433, Universidade Regional do Noroeste do Estado do Rio Grande do Sul), Maria Letícia R Ikeda (0000-0002-2727-2298, Universidade do Vale do Rio dos Sinos), Débora Da Cruz Payão Pellegrini (0000-0002-4285-5643, Universidade Federal do Pampa), Cézane Priscila Reuter (0000-0002-4549-3959, Universidade de Santa Cruz do Sul), Shana G Silva (0000-0003-1504-6936, Universidade Federal da Fronteira Sul), Odir Antonio Dellagostin (0000-0003-2803-4088, Universidade Federal de Pelotas), Pedro Rodrigues Curi Hallal (0000-0003-1470-6461, Universidade Federal de Pelotas)
Año2021
Volumen55
Páginas78
Fecha de publicación2021-11-22
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaRevista de Saúde Pública (JOURNAL)
Identificadores de la revistaISSN: 0034-8910 • E-ISSN: 0034-8910
EditorialUniversidade de São Paulo. Agência de Bibliotecas e Coleções Digitais (PUBLISHER)
DOI10.11606/s1518-8787.2021055004075
PMID34816981
OpenAlexW3213005419
IdiomaEN
Citas recibidas4
Referencias citadas8

OBJECTIVE: To describe the evolution of seropositivity in the State of Rio Grande do Sul, Brazil, through 10 consecutive surveys conducted between April 2020 and April 2021. METHODS: Nine cities covering all regions of the State were studied, 500 households in each city. One resident in each household was randomly selected for testing. In survey rounds 1–8 we used the rapid WONDFO SARS-CoV-2 Antibody Test (Wondfo Biotech Co., Guangzhou, China). In rounds 9–10, we used a direct ELISA test that identifies IgG to the viral S protein (S-UFRJ). In terms of social distancing, individuals were asked three questions, from which we generated an exposure score using principal components analysis. RESULTS: Antibody prevalence in early April 2020 was 0.07%, increasing to 10.0% in February 2021, and to 18.2% in April 2021. In round 10, self-reported whites showed the lowest seroprevalence (17.3%), while indigenous individuals presented the highest (44.4%). Seropositivity increased by 40% when comparing the most with the least exposed. CONCLUSIONS: The proportion of the population already infected by SARS-Cov-2 in the state is still far from any perspective of herd immunity and the infection affects population groups in very different levels

Antibody · Biology · Coronavirus disease 2019 (COVID-19) · Environmental health · Geography · Herd immunity · Indigenous · Population · Serology · Seroprevalence · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) · Veterinary medicine · COVID-19 Clinical Research Studies · Demography · Immunology · Medicine · SARS-CoV-2 and COVID-19 Research · SARS-CoV-2 detection and testing