What do patients value as incentives for participation in clinical trials? A pilot discrete choice experiment

Datos Bibliográficos

ID21787616
AutoresAkke Vellinga (0000-0002-6583-4300, autor de correspondencia), Colum Devine, Min Yun Ho, Colin P Clarke (0000-0003-4387-6515, Ollscoil na Gaillimhe – University of Galway), Colin Clarke (0000-0003-1044-2390, National University of Ireland), Patrick Leahy (University College Cork), Jane Bourke (0000-0002-3994-3239, University College Cork), Declan Devane (0000-0002-9393-7075), Sinead Duane (0000-0002-9228-7322, Ollscoil na Gaillimhe – University of Galway), Patricia Kearney (University College Cork), Patricia M Kearney (0000-0001-9599-3540, University College Cork)
Año2020
Volumen16
Número1-2
Páginas1-12
Fecha de publicación2020-01-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaResearch Ethics (JOURNAL)
Identificadores de la revistaISSN: 1747-0161 • E-ISSN: 2047-6094
EditorialSAGE Publications (PUBLISHER • US)
DOI10.1177/1747016119898669
OpenAlexW3002462734
IdiomaEN
Citas recibidas5
Referencias citadas24

Incentivising has shown to improve participation in clinical trials. However, ethical concerns suggest that incentives may be coercive, obscure trial risks and encourage individuals to enrol in clinical trials for the wrong reasons. The aim of our study was to develop and pilot a discrete choice experiment (DCE) to explore and identify preferences for incentives. A DCE was designed by including following attributes (and levels) of incentives: value, method, and time involvement. To account for trial benefit and risk, each was included as an attribute with levels low, medium and high. For testing purposes, the DCE was administrated using SurveyMonkey in a population of third level students. A total of 245 students, representative of the general student population, participated in the online DCE. The results provide a template to assess and explore the use of different incentive methods in clinical trials. The template can be used in its current format or adapted to particular scenarios. This pilot study provides a feasible methodology to explore the use of incentives for participation in clinical trials and can be adapted to specific trial requirements to provide information for ethical applications or identify the most favourable incentive for participation in clinical trials

Actuarial science · Business · Clinical trial · Economics · Environmental health · Incentive · Medical education · Microeconomics · Population · Research design · Statistics · Computer Science · Ethics in Clinical Research · Medicine · Patient-Provider Communication in Healthcare · Pharmaceutical industry and healthcare · Psychology