C Q Jiang
Biographic Data
| ID | 106350 |
|---|---|
| NAME | C Q Jiang |
| GIVEN NAMES | C Q |
| FAMILY NAME | Jiang |
| SIGNATURE | JIANG C Q |
| AFFILIATIONS | Twelfth Guangzhou City People's Hospital |
| ORCID | 0000-0001-6589-1068 |
| VERIFIED | Yes |
| TOTAL WORKS | 26 |
| TOTAL CITATIONS | 32 |
| AUTHOR COUNT | 26 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2002 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 4 |
Association of fish and meat consumption with non-alcoholic fatty liver disease
High consumption of fatty fish was associated with higher NAFLD risk. Our results, if causal, provide evidence that limiting consumption of fatty fish can be considered as part of NAFLD lifestyle prevention and treatment
Obesity indicators as mediators of association between daytime napping and type 2 diabetes mellitus
Our results showed significant mediating effects of WC, WHR and WHtR on the association between daytime napping and T2DM, suggesting that waist circumference management could be important in daytime nappers
White blood cell count and all-cause and cause-specific mortality in the Guangzhou biobank cohort study
Elevated WBC, specifically granulocyte, count was associated with all-cause, CHD and respiratory mortality in southern Chinese. Further investigation is warranted to clarify whether decreasing inflammation would attenuate WBC count associated mortality
Liver enzymes and incident diabetes in China
BACKGROUND: Impaired liver function has been shown to be associated with incident diabetes. The independent role of the different liver enzymes, including γ-glutamyltransferase (GGT), alanine transaminase (ALT) and aspartate transaminase (AST), has not been addressed properly, taking into account their high collinearity. We used partial least squares (PLS) regression to identify the contribution of ALT, AST and GGT, which appears causally associa…
Height, its components, and coagulability among older Chinese
OBJECTIVES: The causal role of some cardiovascular risk factors, such as HDL cholesterol, has been increasingly challenged and attention is returning to all elements of Virchow's triad, i.e., hypercoagulability (including viscosity) as well as endothelial function and blood flow. We examined the life course origins of coagulability. METHODS: We used multivariable linear regression to assess whether childhood influences, proxied by height and its …
Genetically predicted 17β-estradiol and systemic inflammation in women
BACKGROUND: Many chronic diseases are characterised by low-grade systemic inflammation. Oestrogens may promote immune response consistent with sex-specific patterns of diseases. In vitro culture and animal experiments suggest oestrogens are anti-inflammatory and might thereby protect against low-grade systemic inflammation. Evidence from epidemiological studies is limited. Using a Mendelian randomisation analysis with a separate-sample instrument…
Inequality and inequity in access to health care and treatment for chronic conditions in China
Non-communicable diseases (NCDs) are a large and rapidly-growing problem in China and other middle-income countries. Clinical treatment of NCDs is long-term and expensive, so it may present particular problems for equality and horizontal equity (equal treatment for equal need) in access to health care, although little is known about this at present in low- and middle-income countries. To address this gap, and inform policy for a substantial propo…
Systematic differences among never, occasional and moderate alcohol users in southern China, and its use in alcohol research
BACKGROUND: Western observational studies show moderate alcohol use, compared with never use, positively associated with health. Moderate users differ systematically from others, making these observations vulnerable to confounding. Observations from other contexts may help distinguish whether these associations are confounded. To assess whether southern Chinese would provide a more suitable setting to examine the association of moderate alcohol u…
Life-course origins of social inequalities in adult immune cell markers of inflammation in a developing southern Chinese population
Low SEP throughout life may negatively impact late adult immune-inflammatory status. However, some aspects of immune-inflammatory status may be sensitive to earlier exposures, with sex-specific associations. The findings were compatible with the hypothesis that in a developing population, upregulation of the gonadotropic axis with economic development may obscure the normally protective effects of social advantage for men
Intergenerational influences on diabetes in a developing population
OBJECTIVES: Intergenerational "mismatch" and/or growth conditions may be relevant to the epidemic of diabetes in developing populations. In a rapidly developing southern Chinese population, we tested whether maternal environment, proxied by maternal literacy, or family socio-economic position (SEP), proxied by paternal literacy, were associated with fasting glucose and diabetes. To assess if intergenerational mismatch contributed, we tested wheth…
Does childhood meat eating contribute to sex differences in risk factors for ischaemic heart disease in a developing population
BACKGROUND: A male epidemic of ischaemic heart disease (IHD) emerges with economic development. It has previously been hypothesised that this epidemic is due to nutritionally driven levels of pubertal sex steroids, which lead to a more atherogenic body shape and lipid profile in boys but not girls, without any sex-specific effects on glucose metabolism. This study tests this hypothesis by examining the association of childhood meat eating with IH…
P2-395 Socioeconomic influences at different life stages on self-rated health in Guangzhou, China
Introduction In long-term developed countries socioeconomic position across the life course is positively associated with health. We examined these associations in a developing country with a history of efforts to reorganise social hierarchy. Methods Taking a life course perspective, we used multivariable logistic regression to analyse the association of socioeconomic disadvantage at four life stages (measured by parental possessions, education, …
P2-133 Muscle mass is associated with diabetes in a developing population
Introduction Asian populations tend to be more susceptible to type 2 diabetes. In Asians low muscle-mass may also be a contributory factor. In a rapidly developing southern Chinese population, we examined whether skeletal muscle-mass, proxied by serum creatinine, was associated with diabetes or adiposity. Methods In 9768 older (≥50 years) adults from the Guangzhou Biobank Cohort Study (phase 1) examined in 2003–2004, we used multivariable logisti…
P1-4 ALDH2 is a valid instrument for mendelian randomisation studies in alcohol epidemiology—the Guangzhou Biobank Cohort Study
Introduction Western observational studies show moderate alcohol use positively associated with many health outcomes. Moderate alcohol users differ systematically from others, making these observations susceptible to residual confounding. A randomised controlled trial of moderate alcohol use is unlikely to be possible. A Mendelian randomisation design using a genetic polymorphism affecting alcohol use ( ALDH2 ) as an instrumental variable offers …
P2-132 Intergenerational influences on diabetes in a developing population
Introduction Intergenerational “mismatch” has been suggested as being relevant to the emergent epidemic of diabetes in developing populations. Conversely, constrained growth conditions over generations may also increase susceptibility to diabetes. In a rapidly developing southern Chinese population, we tested whether maternal environment, proxied by maternal literacy, or family socio-economic position (SEP), proxied by paternal literacy, were ass…
P2-471 Liver function related viruses and diabetes in China
Introduction Compared to western populations, diabetes mellitus is prevalent in China despite a relatively non-obese population. Exposures beyond lifestyle and genetics may be relevant. We hypothesised that liver infections, common in China, increase vulnerability to diabetes, via the physiological consequences of poor liver function. Methods We used multivariable regression to examine the adjusted associations of alanine transaminase (ALT) and a…
Socioeconomic influences at different life stages on health in Guangzhou, China
Leg length and age of puberty among men and women from a developing population
OBJECTIVES: Leg length and relative leg length are considered to be reliable markers of prepubertal living conditions. Cessation of leg growth, driven by estrogen, occurs earlier in puberty in girls than boys. We hypothesized that leg length and relative leg length, as sitting height to leg ratio, might have sex-specific associations with age of puberty. METHODS: We used multivariable linear regression in 10,046 older (>or=50 years) Chinese from …
Smoking cessation and carotid atherosclerosis
INTRODUCTION: Smoking has been shown to be associated with carotid atherosclerosis in cross-sectional and prospective studies in Western populations. However, few studies have examined the reversal of risk resulting from quitting smoking, and the results are conflicting. METHODS: 959 men aged 50-85 years were randomly selected from phase III (2006-2007) of the Guangzhou Biobank Cohort Study into this cross-sectional study. Common carotid artery i…
Providing Smoking Cessation Services and Its Relationship with Knowledge and Attitudes
China is the largest consumer of tobacco in the world and there are currently 360 million smokers in China. Smoking cessation is critical in fighting the tobacco epidemic, and nurses, the largest group of health care providers, play an important role in smoking cessation. China now is only at its early stage in capacity building for smoking cessation counsellors and the experience of Hong Kong, 20 years ahead in tobacco control, in developing nur…
Alcohol use and fasting glucose in a developing southern Chinese population
BACKGROUND: In observational studies, mainly from Western Caucasian populations, moderate alcohol use has been shown to be associated with a lower risk of diabetes. However, whether the protection is due to the attributes of alcohol or to those of moderate alcohol users is difficult to disentangle. A population with a different distribution of alcohol consumption and diabetes prevalence from Western populations was studied as a counterfactual com…
Are longer legs associated with enhanced fertility in Chinese women?☆
Are height and leg length universal markers of childhood conditions? The Guangzhou Biobank cohort study
OBJECTIVE: In developed western populations longer legs have been shown to be a marker of better early childhood conditions. In the first generations to experience the epidemiologic transition and associated economic development, epigenetic constraints on growth might preclude improved childhood conditions from increasing leg growth or height. DESIGN, SETTING AND PARTICIPANTS: Multivariable linear regression was used to assess the association of …
Is leg length a biomarker of childhood conditions in older Chinese women? The Guangzhou Biobank Cohort Study
OBJECTIVE: In developed western populations longer legs have been shown to be a biomarker of better early childhood conditions. It was hypothesised that in transitioning populations better childhood conditions may bring forward puberty and thus decrease leg length, counteracting the overall positive effect of a favourable childhood environment on leg growth. DESIGN: Structural equation modelling was used to assess the interrelationship of age, ed…
Characteristics of Chinese Suicide Attempters
Studying the characteristics of attempted suicide is helpful in knowing the background of some completed suicides and improving prevention or intervention strategies. This current study analyzed data of 74 suicide attempters and 92 accident injured patients admitted to 6 hospital emergency rooms in an area of Northeastern China and found both similarities and differences between Chinese and Western suicide attempters. The data show that more wome…
Are height and leg length universal markers of childhood conditions? The Guangzhou Biobank cohort study
OBJECTIVE: In developed western populations longer legs have been shown to be a marker of better early childhood conditions. In the first generations to experience the epidemiologic transition and associated economic development, epigenetic constraints on growth might preclude improved childhood conditions from increasing leg growth or height. DESIGN, SETTING AND PARTICIPANTS: Multivariable linear regression was used to assess the association of …
Inequality and inequity in access to health care and treatment for chronic conditions in China
Non-communicable diseases (NCDs) are a large and rapidly-growing problem in China and other middle-income countries. Clinical treatment of NCDs is long-term and expensive, so it may present particular problems for equality and horizontal equity (equal treatment for equal need) in access to health care, although little is known about this at present in low- and middle-income countries. To address this gap, and inform policy for a substantial propo…
Is leg length a biomarker of childhood conditions in older Chinese women? The Guangzhou Biobank Cohort Study
OBJECTIVE: In developed western populations longer legs have been shown to be a biomarker of better early childhood conditions. It was hypothesised that in transitioning populations better childhood conditions may bring forward puberty and thus decrease leg length, counteracting the overall positive effect of a favourable childhood environment on leg growth. DESIGN: Structural equation modelling was used to assess the interrelationship of age, ed…
Socioeconomic influences at different life stages on health in Guangzhou, China
Characteristics of Chinese Suicide Attempters
Studying the characteristics of attempted suicide is helpful in knowing the background of some completed suicides and improving prevention or intervention strategies. This current study analyzed data of 74 suicide attempters and 92 accident injured patients admitted to 6 hospital emergency rooms in an area of Northeastern China and found both similarities and differences between Chinese and Western suicide attempters. The data show that more wome…
Liver enzymes and incident diabetes in China
BACKGROUND: Impaired liver function has been shown to be associated with incident diabetes. The independent role of the different liver enzymes, including γ-glutamyltransferase (GGT), alanine transaminase (ALT) and aspartate transaminase (AST), has not been addressed properly, taking into account their high collinearity. We used partial least squares (PLS) regression to identify the contribution of ALT, AST and GGT, which appears causally associa…
Smoking cessation and carotid atherosclerosis
INTRODUCTION: Smoking has been shown to be associated with carotid atherosclerosis in cross-sectional and prospective studies in Western populations. However, few studies have examined the reversal of risk resulting from quitting smoking, and the results are conflicting. METHODS: 959 men aged 50-85 years were randomly selected from phase III (2006-2007) of the Guangzhou Biobank Cohort Study into this cross-sectional study. Common carotid artery i…
Alcohol use and fasting glucose in a developing southern Chinese population
BACKGROUND: In observational studies, mainly from Western Caucasian populations, moderate alcohol use has been shown to be associated with a lower risk of diabetes. However, whether the protection is due to the attributes of alcohol or to those of moderate alcohol users is difficult to disentangle. A population with a different distribution of alcohol consumption and diabetes prevalence from Western populations was studied as a counterfactual com…
Smoking and mortality in 81 344 drivers in Guangzhou, China
Objectives: To analyse a policy dilemma in China on public health versus the tobacco economy through additional cigarette tax. Methods: Using published statistics from 1980 through 1997 to estimate the impact of tobacco production and consumption on government revenue and the entire economy. These estimates relied on the results of estimated price elasticities of the demand for cigarettes in China. Results: Given the estimated price elasticities …
Characteristics of Chinese Suicide Attempters
Studying the characteristics of attempted suicide is helpful in knowing the background of some completed suicides and improving prevention or intervention strategies. This current study analyzed data of 74 suicide attempters and 92 accident injured patients admitted to 6 hospital emergency rooms in an area of Northeastern China and found both similarities and differences between Chinese and Western suicide attempters. The data show that more wome…
Are longer legs associated with enhanced fertility in Chinese women?☆
Are height and leg length universal markers of childhood conditions? The Guangzhou Biobank cohort study
OBJECTIVE: In developed western populations longer legs have been shown to be a marker of better early childhood conditions. In the first generations to experience the epidemiologic transition and associated economic development, epigenetic constraints on growth might preclude improved childhood conditions from increasing leg growth or height. DESIGN, SETTING AND PARTICIPANTS: Multivariable linear regression was used to assess the association of …
Is leg length a biomarker of childhood conditions in older Chinese women? The Guangzhou Biobank Cohort Study
OBJECTIVE: In developed western populations longer legs have been shown to be a biomarker of better early childhood conditions. It was hypothesised that in transitioning populations better childhood conditions may bring forward puberty and thus decrease leg length, counteracting the overall positive effect of a favourable childhood environment on leg growth. DESIGN: Structural equation modelling was used to assess the interrelationship of age, ed…
Providing Smoking Cessation Services and Its Relationship with Knowledge and Attitudes
China is the largest consumer of tobacco in the world and there are currently 360 million smokers in China. Smoking cessation is critical in fighting the tobacco epidemic, and nurses, the largest group of health care providers, play an important role in smoking cessation. China now is only at its early stage in capacity building for smoking cessation counsellors and the experience of Hong Kong, 20 years ahead in tobacco control, in developing nur…
Alcohol use and fasting glucose in a developing southern Chinese population
BACKGROUND: In observational studies, mainly from Western Caucasian populations, moderate alcohol use has been shown to be associated with a lower risk of diabetes. However, whether the protection is due to the attributes of alcohol or to those of moderate alcohol users is difficult to disentangle. A population with a different distribution of alcohol consumption and diabetes prevalence from Western populations was studied as a counterfactual com…
Leg length and age of puberty among men and women from a developing population
OBJECTIVES: Leg length and relative leg length are considered to be reliable markers of prepubertal living conditions. Cessation of leg growth, driven by estrogen, occurs earlier in puberty in girls than boys. We hypothesized that leg length and relative leg length, as sitting height to leg ratio, might have sex-specific associations with age of puberty. METHODS: We used multivariable linear regression in 10,046 older (>or=50 years) Chinese from …
Smoking cessation and carotid atherosclerosis
INTRODUCTION: Smoking has been shown to be associated with carotid atherosclerosis in cross-sectional and prospective studies in Western populations. However, few studies have examined the reversal of risk resulting from quitting smoking, and the results are conflicting. METHODS: 959 men aged 50-85 years were randomly selected from phase III (2006-2007) of the Guangzhou Biobank Cohort Study into this cross-sectional study. Common carotid artery i…
Intergenerational influences on diabetes in a developing population
OBJECTIVES: Intergenerational "mismatch" and/or growth conditions may be relevant to the epidemic of diabetes in developing populations. In a rapidly developing southern Chinese population, we tested whether maternal environment, proxied by maternal literacy, or family socio-economic position (SEP), proxied by paternal literacy, were associated with fasting glucose and diabetes. To assess if intergenerational mismatch contributed, we tested wheth…
Does childhood meat eating contribute to sex differences in risk factors for ischaemic heart disease in a developing population
BACKGROUND: A male epidemic of ischaemic heart disease (IHD) emerges with economic development. It has previously been hypothesised that this epidemic is due to nutritionally driven levels of pubertal sex steroids, which lead to a more atherogenic body shape and lipid profile in boys but not girls, without any sex-specific effects on glucose metabolism. This study tests this hypothesis by examining the association of childhood meat eating with IH…
P2-395 Socioeconomic influences at different life stages on self-rated health in Guangzhou, China
Introduction In long-term developed countries socioeconomic position across the life course is positively associated with health. We examined these associations in a developing country with a history of efforts to reorganise social hierarchy. Methods Taking a life course perspective, we used multivariable logistic regression to analyse the association of socioeconomic disadvantage at four life stages (measured by parental possessions, education, …
P2-133 Muscle mass is associated with diabetes in a developing population
Introduction Asian populations tend to be more susceptible to type 2 diabetes. In Asians low muscle-mass may also be a contributory factor. In a rapidly developing southern Chinese population, we examined whether skeletal muscle-mass, proxied by serum creatinine, was associated with diabetes or adiposity. Methods In 9768 older (≥50 years) adults from the Guangzhou Biobank Cohort Study (phase 1) examined in 2003–2004, we used multivariable logisti…
P1-4 ALDH2 is a valid instrument for mendelian randomisation studies in alcohol epidemiology—the Guangzhou Biobank Cohort Study
Introduction Western observational studies show moderate alcohol use positively associated with many health outcomes. Moderate alcohol users differ systematically from others, making these observations susceptible to residual confounding. A randomised controlled trial of moderate alcohol use is unlikely to be possible. A Mendelian randomisation design using a genetic polymorphism affecting alcohol use ( ALDH2 ) as an instrumental variable offers …
P2-132 Intergenerational influences on diabetes in a developing population
Introduction Intergenerational “mismatch” has been suggested as being relevant to the emergent epidemic of diabetes in developing populations. Conversely, constrained growth conditions over generations may also increase susceptibility to diabetes. In a rapidly developing southern Chinese population, we tested whether maternal environment, proxied by maternal literacy, or family socio-economic position (SEP), proxied by paternal literacy, were ass…
P2-471 Liver function related viruses and diabetes in China
Introduction Compared to western populations, diabetes mellitus is prevalent in China despite a relatively non-obese population. Exposures beyond lifestyle and genetics may be relevant. We hypothesised that liver infections, common in China, increase vulnerability to diabetes, via the physiological consequences of poor liver function. Methods We used multivariable regression to examine the adjusted associations of alanine transaminase (ALT) and a…
Socioeconomic influences at different life stages on health in Guangzhou, China
Life-course origins of social inequalities in adult immune cell markers of inflammation in a developing southern Chinese population
Low SEP throughout life may negatively impact late adult immune-inflammatory status. However, some aspects of immune-inflammatory status may be sensitive to earlier exposures, with sex-specific associations. The findings were compatible with the hypothesis that in a developing population, upregulation of the gonadotropic axis with economic development may obscure the normally protective effects of social advantage for men
Inequality and inequity in access to health care and treatment for chronic conditions in China
Non-communicable diseases (NCDs) are a large and rapidly-growing problem in China and other middle-income countries. Clinical treatment of NCDs is long-term and expensive, so it may present particular problems for equality and horizontal equity (equal treatment for equal need) in access to health care, although little is known about this at present in low- and middle-income countries. To address this gap, and inform policy for a substantial propo…
Systematic differences among never, occasional and moderate alcohol users in southern China, and its use in alcohol research
BACKGROUND: Western observational studies show moderate alcohol use, compared with never use, positively associated with health. Moderate users differ systematically from others, making these observations vulnerable to confounding. Observations from other contexts may help distinguish whether these associations are confounded. To assess whether southern Chinese would provide a more suitable setting to examine the association of moderate alcohol u…
Height, its components, and coagulability among older Chinese
OBJECTIVES: The causal role of some cardiovascular risk factors, such as HDL cholesterol, has been increasingly challenged and attention is returning to all elements of Virchow's triad, i.e., hypercoagulability (including viscosity) as well as endothelial function and blood flow. We examined the life course origins of coagulability. METHODS: We used multivariable linear regression to assess whether childhood influences, proxied by height and its …
Genetically predicted 17β-estradiol and systemic inflammation in women
BACKGROUND: Many chronic diseases are characterised by low-grade systemic inflammation. Oestrogens may promote immune response consistent with sex-specific patterns of diseases. In vitro culture and animal experiments suggest oestrogens are anti-inflammatory and might thereby protect against low-grade systemic inflammation. Evidence from epidemiological studies is limited. Using a Mendelian randomisation analysis with a separate-sample instrument…
Liver enzymes and incident diabetes in China
BACKGROUND: Impaired liver function has been shown to be associated with incident diabetes. The independent role of the different liver enzymes, including γ-glutamyltransferase (GGT), alanine transaminase (ALT) and aspartate transaminase (AST), has not been addressed properly, taking into account their high collinearity. We used partial least squares (PLS) regression to identify the contribution of ALT, AST and GGT, which appears causally associa…
White blood cell count and all-cause and cause-specific mortality in the Guangzhou biobank cohort study
Elevated WBC, specifically granulocyte, count was associated with all-cause, CHD and respiratory mortality in southern Chinese. Further investigation is warranted to clarify whether decreasing inflammation would attenuate WBC count associated mortality
Obesity indicators as mediators of association between daytime napping and type 2 diabetes mellitus
Our results showed significant mediating effects of WC, WHR and WHtR on the association between daytime napping and T2DM, suggesting that waist circumference management could be important in daytime nappers
Medicine (26 works) · Cohort study (19 works) · Internal Medicine (18 works) · Cohort (17 works) · Environmental health (17 works) · Population (15 works) · Demography (14 works) · Internal Medicine (11 works) · Biobank (9 works) · Gerontology (8 works)