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Sylvia Culp

Biographic Data

ID1170872
NAMESylvia Culp
GIVEN NAMESSylvia
FAMILY NAMECulp
SIGNATURECULP S
AFFILIATIONSWestern Michigan University
VERIFIEDNo
TOTAL WORKS3
TOTAL CITATIONS24
AUTHOR COUNT3
EDITOR COUNT0
FIRST PUBLICATION YEAR1989
LATEST PUBLICATION YEAR1997
H-INDEX2
  • Establishing Genotype/Phenotype Relationships

    Open Access•Sylvia Culp•ARTICLE•Philosophy of Science•1997•Cited by: 1•References: 18

    In this paper, I examine an experimental technique, gene targeting, used for establishing genotype/phenotype relationships. Through analyzing a case study, I identify many pitfalls that may lead to false conclusions about these relationships. I argue that some of these pitfalls may seriously affect gene targeting's usefulness for associating phenotypes with genes cataloged by the Human Genome Project. This case also shows the use of gene targeted…

  • Objectivity in Experimental Inquiry

    Open Access•Sylvia Culp•ARTICLE•Philosophy of Science•1995•Cited by: 18•References: 20

    I respond to H. M. Collins's claim (1985, 1990, 1993) that experimental inquiry cannot be objective because the only criterium experimentalists have for determining whether a technique is “working” is the production of “correct” (i.e., the expected) data. Collins claims that the “experimenters' regress,” the name he gives to this data-technique circle, cannot be broken using the resources of experiment alone. I argue that the data-technique circl…

  • Theory Structure and Theory Change in Contemporary Molecular Biology

    Sylvia Culp, Philip Kitcher•ARTICLE•The British Journal for the…•1989•Cited by: 5•References: 26

    Traditional approaches to theory structure and theory change in science do not fare well when confronted with the practice of certain fields of science. We offer an account of contemporary practice in molecular biology designed to address two questions: Is theory change in this area of science gradual or saltatory? What is the relation between molecular biology and the fields of traditional biology? Our main focus is a recent episode in molecular…

  • Objectivity in Experimental Inquiry

    Open Access•Sylvia Culp•ARTICLE•Philosophy of Science•1995•Cited by: 18•References: 20

    I respond to H. M. Collins's claim (1985, 1990, 1993) that experimental inquiry cannot be objective because the only criterium experimentalists have for determining whether a technique is “working” is the production of “correct” (i.e., the expected) data. Collins claims that the “experimenters' regress,” the name he gives to this data-technique circle, cannot be broken using the resources of experiment alone. I argue that the data-technique circl…

  • Theory Structure and Theory Change in Contemporary Molecular Biology

    Sylvia Culp, Philip Kitcher•ARTICLE•The British Journal for the…•1989•Cited by: 5•References: 26

    Traditional approaches to theory structure and theory change in science do not fare well when confronted with the practice of certain fields of science. We offer an account of contemporary practice in molecular biology designed to address two questions: Is theory change in this area of science gradual or saltatory? What is the relation between molecular biology and the fields of traditional biology? Our main focus is a recent episode in molecular…

  • Establishing Genotype/Phenotype Relationships

    Open Access•Sylvia Culp•ARTICLE•Philosophy of Science•1997•Cited by: 1•References: 18

    In this paper, I examine an experimental technique, gene targeting, used for establishing genotype/phenotype relationships. Through analyzing a case study, I identify many pitfalls that may lead to false conclusions about these relationships. I argue that some of these pitfalls may seriously affect gene targeting's usefulness for associating phenotypes with genes cataloged by the Human Genome Project. This case also shows the use of gene targeted…

  • Theory Structure and Theory Change in Contemporary Molecular Biology

    Sylvia Culp, Philip Kitcher•ARTICLE•The British Journal for the…•1989•Cited by: 5•References: 26

    Traditional approaches to theory structure and theory change in science do not fare well when confronted with the practice of certain fields of science. We offer an account of contemporary practice in molecular biology designed to address two questions: Is theory change in this area of science gradual or saltatory? What is the relation between molecular biology and the fields of traditional biology? Our main focus is a recent episode in molecular…

  • Objectivity in Experimental Inquiry

    Open Access•Sylvia Culp•ARTICLE•Philosophy of Science•1995•Cited by: 18•References: 20

    I respond to H. M. Collins's claim (1985, 1990, 1993) that experimental inquiry cannot be objective because the only criterium experimentalists have for determining whether a technique is “working” is the production of “correct” (i.e., the expected) data. Collins claims that the “experimenters' regress,” the name he gives to this data-technique circle, cannot be broken using the resources of experiment alone. I argue that the data-technique circl…

  • Establishing Genotype/Phenotype Relationships

    Open Access•Sylvia Culp•ARTICLE•Philosophy of Science•1997•Cited by: 1•References: 18

    In this paper, I examine an experimental technique, gene targeting, used for establishing genotype/phenotype relationships. Through analyzing a case study, I identify many pitfalls that may lead to false conclusions about these relationships. I argue that some of these pitfalls may seriously affect gene targeting's usefulness for associating phenotypes with genes cataloged by the Human Genome Project. This case also shows the use of gene targeted…

Biology (2 works) · Computer Science (2 works) · Epistemology (2 works) · Philosophy (2 works) · Philosophy and History of Science (2 works) · Affect (linguistics) (1 work) · Computational biology (1 work) · Focus (optics) (1 work) · Gene (1 work) · Genetics (1 work)

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