Eric T Juengst
Biographic Data
| ID | 142225 |
|---|---|
| NAME | Eric T Juengst |
| GIVEN NAMES | Eric T |
| FAMILY NAME | Juengst |
| SIGNATURE | JUENGST E T |
| AFFILIATIONS | University of North Carolina at Chapel Hill |
| ORCID | 0000-0002-8374-5774 |
| VERIFIED | Yes |
| TOTAL WORKS | 22 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 22 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1980 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 0 |
Preventive Human Genome Editing and Enhancement
While somatic cell editing to treat disease is widely accepted, the use of human genome editing for “enhancement” remains contested. Scientists and policy‐makers routinely cite the prospect of enhancement as a salient ethical challenge for human genome editing research. If preventive genome editing projects are perceived as pursuing human enhancement, they could face heightened barriers to scientific, public, and regulatory approval. This article…
Human heritable genome editing and its governance
Heritable human genome editing has garnered significant attention in scholarly and lay media, yet questions remain about whether, when, and how heritable genome editing ought to proceed. Drawing on interviews with scientists who use genome editing in their research and professionals engaged in human genome editing governance efforts, we examine their views on the permissibility of heritable genome editing and the governance strategies they see as…
Prevention” and Human Gene Editing Governance
The Holocaust and the racial hygiene doctrine that helped rationalize it still overshadow contemporary debates about using gene editing for disease prevention. In part, this is because prevention can mean 3 different things, which are often conflated. Phenotypic prevention involves modifying the expression of pathogenic DNA variants to forestall their clinical effects in at-risk patients. Genotypic prevention involves controlling transmission of …
Expert stakeholders’ perspectives on a Data-to-Care strategy for improving care among HIV-positive individuals incarcerated in jails
Data-to-Care (D2C) uses surveillance data (e.g., laboratory, Medicaid billing) to identify out-of-care HIV-positive persons to re-link them to care. Most US states are implementing D2C, yet few studies have explored stakeholders' perspectives on D2C, and none have addressed these perspectives in the context of D2C in jail. This article reports findings from qualitative, semi-structured interviews conducted with expert stakeholders regarding their…
Genomic Essentialism
Since the inception of large‐scale human genome research, there has been much caution about the risks of exacerbating a number of socially dangerous attitudes linked to human genetics. These attitudes are usually labeled with one of a family of genetic or genomic “isms” or “ations” such as “genetic essentialism,” “genetic determinism,” “genetic reductionism,” “geneticization,” “genetic stigmatization,” and “genetic discrimination.” The psychosoci…
Are Parents Really Obligated to Learn as Much as Possible about Their Children's Genomes
As new parents quickly learn, parenting always involves choosing your battles. Ideally, parents have the freedom to make those moral choices without the prejudice of an unreasonable or premature inflicted ought. Resolving the predictive uncertainties of genomic information is the professional responsibility of the biomedical community, just as clarifying the impact of global warming or assessing the risks of rising multidrug resistance is the res…
Why Does the Shift from “Personalized Medicine” to “Precision Health” and “Wellness Genomics” Matter
Efforts to conceptualize the application of human genomics to health care have displayed an evolving set of translational research goals. Under personalized genomic medicine , the aim was to individualize treatment and empower patients to take more responsibility for their own health. With the rise of interest in expert interpretation of multifactorial risk stratification, emphasis shifted to giving clinicians better tools and more authority to u…
Crowdsourcing the Moral Limits of Human Gene Editing
In 2015, a flourish of “alarums and excursions” by the scientific community propelled CRISPR/Cas9 and other new gene‐editing techniques into public attention. At issue were two kinds of potential gene‐editing experiments in humans: those making inheritable germ‐line modifications and those designed to enhance human traits beyond what is necessary for health and healing. The scientific consensus seemed to be that while research to develop safe and…
Let’s pull these technologies out of the ivory tower”
This paper investigates how groups of ‘citizen scientists’ in non-traditional settings and primarily online networks claim to be challenging conventional genomic research processes and norms. Although these groups are highly diverse, they all distinguish their efforts from traditional university- or industry-based genomic research as being ‘participant-driven’ in one way or another. Participant-driven genomic research (PDGR) groups often work fro…
From “Personalized” to “Precision” Medicine
Since the late 1980s, the human genetics and genomics research community has been promising to usher in a “new paradigm for health care”—one that uses molecular profiling to identify human genetic variants implicated in multifactorial health risks. After the completion of the Human Genome Project in 2003, a wide range of stakeholders became committed to this “paradigm shift,” creating a confluence of investment, advocacy, and enthusiasm that bear…
Personalized Genomic Medicine and the Rhetoric of Empowerment
A decade after the completion of the Human Genome Project, the widespread appeal of personalized genomic medicine's vision and potential virtues for health care remains compelling. Advocates argue that our current medical regime “is in crisis as it is expensive, reactive, inefficient, and focused largely on one size fits all treatments for events of late stage disease.” What is revolutionary about this kind of medicine, its advocates maintain, is…
Population Genetic Research and Screening
Like all community-based public health campaigns, proposals to use genetic information to improve the health and welfare of communities, whether the old eugenic sterilization campaigns or the routinized population screening programs of today's ‘public health genetics’, can involve asking affected individuals to make special sacrifices or assume special responsibilities on behalf of the community's welfare. Moreover, unlike public health intervent…
Can genomics tell me who I am? Essentialistic rhetoric in direct-to-consumer DNA testing
Recently, a high number of companies have emerged that offer online direct-to-consumer DNA testing. We investigate these consumer genomics companies through the lens of identity. We find that many of them appeal to a kind of “genetic essentialism”. We suggest that this appeal is key to understanding why consumers are attracted to their services. There seem to be three very different currents within contemporary culture at work: the pre-modern sea…
Origin Myths in Bioethics
Extraordinary Litmus Tests
Biogerontology, "Anti-Aging Medicine," and the Challenges of Human Enhancement
Eric T. Juengst, Robert H. Binstock, Maxwell Mehlman, Stephen G. Post, Peter Whitehouse, Biogerontology, "Anti-Aging Medicine," and the Challenges of Human Enhancement, The Hastings Center Report, Vol. 33, No. 4 (Jul. - Aug., 2003), pp. 21-30
Genetic testing and the moral dynamics of family life
American families are a segment of the public that will feel the impact of the Human Genome Project most acutely: but they are also one of the least well studied segments with regard to that impact. Three sets of ethical problems, in particular, deserve more scrutiny: the effect of increased genetic risk assessment on family members' willingness to assist their kin discover mutually incriminating genetic risks, its impact on the candor with which…
Enhancing Cognition in the Intellectually Intact
As science learns more about how the brain works, and fails to work, the possibility for developing "cognition enhancers" becomes more plausible. And the demand for drugs that can help us think faster, remember more, and focus more keenly has already been demonstrated by the market success of drugs like Ritalin, which tames the attention span, and Prozac, which ups the competitive edge. The new drug Aricept, which improves memory, most likely wil…
Ethical, Legal, and Social Implications (Elsi) Program National Center for Human Genome Research, National Institutes of Health
The program on the Ethical, Legal, and Social Implications (ELSI) of human genome research is a branch of the National Center for Human Genome Research (NCHGR) at the National Institutes of Health (NIH). The NCHGR is responsible, in conjunction with the Office of Health and Environment at the Department of Energy (DOE), for administration and coordination of the U.S. component of the Human Genome Project
Developing and Delivering New Medical Technologies
The articles in this issue illuminate psychosocial issues raised by the development and delivery of new medical technologies. Five kinds of questions surface repeatedly: questions about a technology's purpose(s), the value judgments it presumes, the locus of its control, the external forces that drive it, and its long‐term social risks. These questions take the discussion of new technologies beyond the challenge of improving access to their benef…
Subtracting Injury from Insult
The emergence of implantable drug delivery systems will allow us to\nproduce the effects of psychosurgery and surgical sterilization without their\nirreversible invasions of bodily integrity. However, this clinical advantage\ndoes not resolve the most important ethical problems these surgeries face, and\nmay even obscure them when they arise in the practice of drug\nimplantation
Symposium report
No prominent works on this page.
Symposium report
Subtracting Injury from Insult
The emergence of implantable drug delivery systems will allow us to\nproduce the effects of psychosurgery and surgical sterilization without their\nirreversible invasions of bodily integrity. However, this clinical advantage\ndoes not resolve the most important ethical problems these surgeries face, and\nmay even obscure them when they arise in the practice of drug\nimplantation
Ethical, Legal, and Social Implications (Elsi) Program National Center for Human Genome Research, National Institutes of Health
The program on the Ethical, Legal, and Social Implications (ELSI) of human genome research is a branch of the National Center for Human Genome Research (NCHGR) at the National Institutes of Health (NIH). The NCHGR is responsible, in conjunction with the Office of Health and Environment at the Department of Energy (DOE), for administration and coordination of the U.S. component of the Human Genome Project
Developing and Delivering New Medical Technologies
The articles in this issue illuminate psychosocial issues raised by the development and delivery of new medical technologies. Five kinds of questions surface repeatedly: questions about a technology's purpose(s), the value judgments it presumes, the locus of its control, the external forces that drive it, and its long‐term social risks. These questions take the discussion of new technologies beyond the challenge of improving access to their benef…
Enhancing Cognition in the Intellectually Intact
As science learns more about how the brain works, and fails to work, the possibility for developing "cognition enhancers" becomes more plausible. And the demand for drugs that can help us think faster, remember more, and focus more keenly has already been demonstrated by the market success of drugs like Ritalin, which tames the attention span, and Prozac, which ups the competitive edge. The new drug Aricept, which improves memory, most likely wil…
Genetic testing and the moral dynamics of family life
American families are a segment of the public that will feel the impact of the Human Genome Project most acutely: but they are also one of the least well studied segments with regard to that impact. Three sets of ethical problems, in particular, deserve more scrutiny: the effect of increased genetic risk assessment on family members' willingness to assist their kin discover mutually incriminating genetic risks, its impact on the candor with which…
Biogerontology, "Anti-Aging Medicine," and the Challenges of Human Enhancement
Eric T. Juengst, Robert H. Binstock, Maxwell Mehlman, Stephen G. Post, Peter Whitehouse, Biogerontology, "Anti-Aging Medicine," and the Challenges of Human Enhancement, The Hastings Center Report, Vol. 33, No. 4 (Jul. - Aug., 2003), pp. 21-30
Extraordinary Litmus Tests
Origin Myths in Bioethics
Population Genetic Research and Screening
Like all community-based public health campaigns, proposals to use genetic information to improve the health and welfare of communities, whether the old eugenic sterilization campaigns or the routinized population screening programs of today's ‘public health genetics’, can involve asking affected individuals to make special sacrifices or assume special responsibilities on behalf of the community's welfare. Moreover, unlike public health intervent…
Can genomics tell me who I am? Essentialistic rhetoric in direct-to-consumer DNA testing
Recently, a high number of companies have emerged that offer online direct-to-consumer DNA testing. We investigate these consumer genomics companies through the lens of identity. We find that many of them appeal to a kind of “genetic essentialism”. We suggest that this appeal is key to understanding why consumers are attracted to their services. There seem to be three very different currents within contemporary culture at work: the pre-modern sea…
Personalized Genomic Medicine and the Rhetoric of Empowerment
A decade after the completion of the Human Genome Project, the widespread appeal of personalized genomic medicine's vision and potential virtues for health care remains compelling. Advocates argue that our current medical regime “is in crisis as it is expensive, reactive, inefficient, and focused largely on one size fits all treatments for events of late stage disease.” What is revolutionary about this kind of medicine, its advocates maintain, is…
From “Personalized” to “Precision” Medicine
Since the late 1980s, the human genetics and genomics research community has been promising to usher in a “new paradigm for health care”—one that uses molecular profiling to identify human genetic variants implicated in multifactorial health risks. After the completion of the Human Genome Project in 2003, a wide range of stakeholders became committed to this “paradigm shift,” creating a confluence of investment, advocacy, and enthusiasm that bear…
Crowdsourcing the Moral Limits of Human Gene Editing
In 2015, a flourish of “alarums and excursions” by the scientific community propelled CRISPR/Cas9 and other new gene‐editing techniques into public attention. At issue were two kinds of potential gene‐editing experiments in humans: those making inheritable germ‐line modifications and those designed to enhance human traits beyond what is necessary for health and healing. The scientific consensus seemed to be that while research to develop safe and…
Let’s pull these technologies out of the ivory tower”
This paper investigates how groups of ‘citizen scientists’ in non-traditional settings and primarily online networks claim to be challenging conventional genomic research processes and norms. Although these groups are highly diverse, they all distinguish their efforts from traditional university- or industry-based genomic research as being ‘participant-driven’ in one way or another. Participant-driven genomic research (PDGR) groups often work fro…
Are Parents Really Obligated to Learn as Much as Possible about Their Children's Genomes
As new parents quickly learn, parenting always involves choosing your battles. Ideally, parents have the freedom to make those moral choices without the prejudice of an unreasonable or premature inflicted ought. Resolving the predictive uncertainties of genomic information is the professional responsibility of the biomedical community, just as clarifying the impact of global warming or assessing the risks of rising multidrug resistance is the res…
Why Does the Shift from “Personalized Medicine” to “Precision Health” and “Wellness Genomics” Matter
Efforts to conceptualize the application of human genomics to health care have displayed an evolving set of translational research goals. Under personalized genomic medicine , the aim was to individualize treatment and empower patients to take more responsibility for their own health. With the rise of interest in expert interpretation of multifactorial risk stratification, emphasis shifted to giving clinicians better tools and more authority to u…
Genomic Essentialism
Since the inception of large‐scale human genome research, there has been much caution about the risks of exacerbating a number of socially dangerous attitudes linked to human genetics. These attitudes are usually labeled with one of a family of genetic or genomic “isms” or “ations” such as “genetic essentialism,” “genetic determinism,” “genetic reductionism,” “geneticization,” “genetic stigmatization,” and “genetic discrimination.” The psychosoci…
Expert stakeholders’ perspectives on a Data-to-Care strategy for improving care among HIV-positive individuals incarcerated in jails
Data-to-Care (D2C) uses surveillance data (e.g., laboratory, Medicaid billing) to identify out-of-care HIV-positive persons to re-link them to care. Most US states are implementing D2C, yet few studies have explored stakeholders' perspectives on D2C, and none have addressed these perspectives in the context of D2C in jail. This article reports findings from qualitative, semi-structured interviews conducted with expert stakeholders regarding their…
Prevention” and Human Gene Editing Governance
The Holocaust and the racial hygiene doctrine that helped rationalize it still overshadow contemporary debates about using gene editing for disease prevention. In part, this is because prevention can mean 3 different things, which are often conflated. Phenotypic prevention involves modifying the expression of pathogenic DNA variants to forestall their clinical effects in at-risk patients. Genotypic prevention involves controlling transmission of …
Preventive Human Genome Editing and Enhancement
While somatic cell editing to treat disease is widely accepted, the use of human genome editing for “enhancement” remains contested. Scientists and policy‐makers routinely cite the prospect of enhancement as a salient ethical challenge for human genome editing research. If preventive genome editing projects are perceived as pursuing human enhancement, they could face heightened barriers to scientific, public, and regulatory approval. This article…
Human heritable genome editing and its governance
Heritable human genome editing has garnered significant attention in scholarly and lay media, yet questions remain about whether, when, and how heritable genome editing ought to proceed. Drawing on interviews with scientists who use genome editing in their research and professionals engaged in human genome editing governance efforts, we examine their views on the permissibility of heritable genome editing and the governance strategies they see as…
Political science (16 works) · Law (12 works) · Psychology (11 works) · Biology (10 works) · Biomedical Ethics and Regulation (10 works) · Medicine (9 works) · Sociology (8 works) · Engineering (7 works) · Engineering ethics (7 works) · Genetics (7 works)