Isabela Judith Martins Bensenor
Biographic Data
| ID | 150544 |
|---|---|
| NAME | Isabela Judith Martins Bensenor |
| GIVEN NAMES | Isabela Judith Martins |
| FAMILY NAME | Bensenor |
| SIGNATURE | BENSENOR I J M |
| AFFILIATIONS | Universidade de São Paulo |
| ORCID | 0000-0002-6723-5678 |
| VERIFIED | Yes |
| TOTAL WORKS | 97 |
| TOTAL CITATIONS | 104 |
| AUTHOR COUNT | 97 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2007 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 7 |
Effects of short sleep and sleep deprivation on thyroid hormones and indices: A Bayesian multilevel analysis from the Elsa-Brasil cohort
Short sleep duration and sleep deprivation are increasingly frequent in the population and associated with negative health outcomes. Few longitudinal studies have assessed the influence of sleep parameters on thyroid hormones and related indices. This study aimed to analyze the longitudinal association between short sleep duration and sleep deprivation and thyroid hormones and indices, stratified by sex. This prospective cohort analysis included …
Inefficiencies identified in healthcare professional-to-patient handover practices for atrial fibrillation: A mixed-methods study in Brazil, China and Sri Lanka
Introduction Information continuity and self-care are important for optimal management of atrial fibrillation (AF) to reduce complications (eg, stroke) and improve prognosis and patient satisfaction. This can be achieved through handover of information from healthcare professionals (HCPs) to patients. Methods In Brazil, China and Sri Lanka, we conducted a mixed-methods study to identify cross-country differences, similarities, barriers and facili…
Dietary patterns derived from three diet quality indices and associated factors: Findings from the baseline of Elsa-Brasil
The aim of this study was to describe dietary patterns using three diet quality indices and the associated factors among 15,081 participants from the baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Dietary intake was assessed through a food frequency questionnaire. Three diet quality indices were applied: the Planetary Health Diet Index (PHDI), the Cardiovascular Health Diet Index (CHDI), and the Healthy Eating Index-2…
Padrões alimentares derivados de três índices de qualidade da dieta e fatores associados: Resultados da linha de base do Elsa-Brasil
O objetivo deste estudo foi descrever os padrões alimentares através de três índices de qualidade da dieta e os fatores associados entre 15.081 participantes da linha de base do Estudo Longitudinal de Saúde do Adulto (ELSA- Brasil). O consumo alimentar foi avaliado por meio de questionário de frequência alimentar. A partir disso, foram aplicados três índices de qualidade da dieta: o Índice de Dieta da Saúde Planetária (PHDI), Índice de Qualidade …
Etapas de desenvolvimento e controle de qualidade no Estudo de Envelhecimento e Funcionamento Cerebral no Elsa-Brasil
OBJECTIVE: To describe all stages of developing strategies and quality control in the Aging and Brain Working Study linked to the Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil – Brazilian Longitudinal Study of Adult Health), a prospective cohort of 15,105 civil servants (aged 35–74) followed up since 2008. METHODS: Based on the sample of participants alive at the beginning of the sample selection in September 2022 (n = 4,566) from ELSA-Bras…
Burden of disease scenarios for 204 countries and territories, 2022–2050: A forecasting analysis for the Global Burden of Disease Study 2021
BACKGROUND: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternativ…
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021
BACKGROUND: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 ri…
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: A comprehensive demographic analysis for the Global Burden of Disease Study 2021
BACKGROUND: Accurate assessments of current and future fertility-including overall trends and changing population age structures across countries and regions-are essential to help plan for the profound social, economic, environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality,…
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: A systematic analysis for the Global Burden of Disease…
BACKGROUND: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mort…
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the Covid-19 pandemic: A compr…
BACKGROUND: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 cou…
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (Dalys), and healthy life expectancy (Hale) for 371 diseases and injuries in 204 countries and territor…
BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to im…
Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021
BACKGROUND: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by…
Are Neighborhood Greenspaces Associated with Leisure-time Physical Activity? Results from Elsa-Brasil Eight-year Follow-up
Dynapenia and sarcopenia: Association with the diagnosis, duration and complication of type 2 diabetes mellitus in Elsa-Brasil
Sarcopenia (the loss of muscle mass, strength and skeletal muscle function) increases mortality and the risk of hospitalization in the older population. Although it is known that older adults with type 2 diabetes mellitus (T2DM) have a higher risk of dynapenia and sarcopenia, few studies have investigated these conditions in middle-aged populations. The objective of this study was to investigate whether T2DM, its duration, the presence of albumin…
Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: A systematic analysis for the Global Burden of Disease Study 2021
BACKGROUND: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes…
Generalisability of and lessons learned from a mixed-methods study conducted in three low- and middle-income countries to identify care pathways for atrial fibrillation
BACKGROUND: Identifying existing care pathways is the first step for understanding how services can be improved to enable early diagnosis and effective follow-up care for non-communicable diseases (NCDs); however, evidence on how care pathways can and should be identified in low- and middle-income countries (LMICs) is lacking. OBJECTIVE: To describe generalisability and lessons learned from recruitment and data collection for the quantitative com…
Association between Leisure-Time and Commute Physical Activity and Pre-Diabetes and Diabetes in the Brazilian Longitudinal Study of Adult Health (Elsa-Brasil)
LTPA was inversely associated with diabetes and pre-diabetes in the ELSA-Brasil participants. A different behavior was observed between genders
Population-level risks of alcohol consumption by amount, geography, age, sex, and year: A systematic analysis for the Global Burden of Disease Study 2020
BACKGROUND: The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year. METHODS: For this analysis, we constructed burden-weighted dose-response relative risk curves across 22 health outcomes to esti…
Elsa-Brasil: A 4-year incidence of hearing loss in adults with and without hypertension
OBJECTIVE To compare the incidence of hearing loss among adults stratified by the occurrence of hypertension, and to investigate the association between hypertension and hearing loss. METHODS Longitudinal observational study, part of the Estudo Longitudinal da Saúde do Adulto (ELSA-Brasil, Longitudinal Study on Adult’s Health). Data from the first and second waves were analyzed, including information from audiological assessment and general healt…
Recommender System Based on Collaborative Filtering for Personalized Dietary Advice: A Cross-Sectional Analysis of the Elsa-Brasil Study
This study aimed to predict dietary recommendations and compare the performance of algorithms based on collaborative filtering for making predictions of personalized dietary recommendations. We analyzed the baseline cross-sectional data (2008-2010) of 12,667 participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The participants were public employees of teaching and research institutions, aged 35-74 years, and 59% female.…
Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: All-cause and cause-specific mortality findings from the Global Burden of Disease Study …
BACKGROUND: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, a…
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: A systematic analysis from the Global Burd…
BACKGROUND: Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. METHODS: We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global B…
Global, regional, and national burden of stroke and its risk factors, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019
BACKGROUND: Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national leve…
Incidence of excess body weight and annual weight gain in women and men: Results from the Elsa‐Brasil cohort
OBJECTIVE: To estimate annual weight gain and the incidence of overweight and obesity, stratified according to gender and socioeconomic factors. METHODS: From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), we included 13 625 women and men aged 35-74 (2008-2010) who attended a follow-up visit after a mean 3.8-years. Standardized questionnaires were used to record sociodemographic data, and height and weight were measured on all pa…
Consumo de bebidas alcoólicas e não alcoólicas: Resultados do Elsa-Brasil
Objetiva-se descrever o consumo de bebidas alcoólicas e não alcoólicas segundo variáveis sociodemográficas, de saúde e localização. Estudo transversal com dados do ELSA-Brasil (2008-2010). Aplicou-se questionário para coleta de dados sociodemográficos, de alimentação, saúde, além de antropometria. Realizou-se análise descritiva e associação com variáveis de interesse. Na amostra, 8% do valor calórico total é proveniente de bebidas não alcoólicas …
Doenças crônicas não transmissíveis no Brasil: Prioridade para enfrentamento e investigação
As Doenças Crônicas Não Transmissíveis representam a maior carga de morbimortalidade no Brasil. Em 2011, o Ministério da Saúde lançou seu Plano de Ações Estratégicas para o Enfrentamento das Doenças Crônicas Não Transmissíveis, enfatizando ações populacionais para controlar as doenças cardiovasculares, diabetes, câncer e doença respiratória crônica, predominantemente pelo controle do fumo, inatividade física, alimentação inadequada e uso prejudic…
Afericoes e exames clinicos realizados nos participantes do Elsa-Brasil
Este artigo descreve os exames clínicos realizados no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Alguns deles (antropometria, pressão arterial e índice tornozelo-braquial) já têm uso clínico consolidado. Outros, como a velocidade de onda de pulso, variabilidade da frequência cardíaca e medida da espessura médio-intimal de carótidas, carecem de valor de referência na população brasileira não doente e podem constituir preditores importan…
Questionario do Elsa-Brasil: Desafios na elaboracao de instrumento multidimensional
O artigo apresenta o processo de elaboração do questionário utilizado no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Iniciamos pelo relato sobre a "Seleção de Temas" abordados no questionário, cujo conteúdo teria que abranger o conhecimento disponível acerca da complexa rede de causalidade dos desfechos de interesse, assim como possibilitar a comparabilidade com estudos semelhantes. Contextualizamos a "tradução e a adaptação de instrume…
Rotinas de organizacao de exames e entrevistas no centro de investigacao Elsa-Brasil
O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é um estudo de coorte prospectivo com avaliações abrangentes ao longo do tempo. O artigo descreve a rotina de exames e entrevistas realizados pelo participante, assim como a estruturação da área física e da equipe dos Centros de Pesquisa. O ELSA-Brasil pressupõe o comparecimento do participante ao Centro de Pesquisa para a realização dos exames e entrevistas segundo protocolos padronizados de…
Logistica de coleta e transporte de material biologico e organizacao do laboratorio central no Elsa-Brasil
O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é um estudo de coorte multicêntrico com o objetivo de identificar os fatores de risco associados ao diabetes tipo 2 e à doença cardiovascular na população brasileira. O artigo descreve as estratégias de coleta, processamento, transporte e de controle de qualidade dos exames de sangue e urina no ELSA. O estudo optou pela centralização dos exames em um único laboratório. O processamento das amo…
Reprodutibilidade e validade relativa do Questionário de Frequência Alimentar do Elsa-Brasil
Avaliou-se a reprodutibilidade e a validade do Questionário de Frequência Alimentar (QFA) utilizado no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Foram aplicados três registros alimentares e um QFA em dois momentos no período de um ano (n = 281). Valores de energia e nutrientes dos registros alimentares foram deatenuados e Log transformados. Para avaliação da reprodutibilidade e validade foi aplicado o teste de correlação intraclasse (…
Chronic kidney disease among adult participants of the Elsa-Brasil cohort: Association with race and socioeconomic position
BACKGROUND: There is increased interest in understanding why chronic kidney disease (CKD) rates vary across races and socioeconomic groups. We investigated the distribution of estimated glomerular filtration rate (eGFR), urinary albumin-creatinine ratio (ACR) and CKD according to these factors in Brazilian adults. METHODS: Using baseline data (2008-2010) of 14,636 public sector employees (35-74 years) enrolled in the Brazilian Longitudinal Study …
Consumption of ultra-processed foods and socioeconomic position: A cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health
The objective of the study was to estimate the contribution of ultra-processed foods to total caloric intake and investigate whether it differs according to socioeconomic position. We analyzed baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil 2008-2010; N = 14.378) and data on dietary intake using a food frequency questionnaire, assigning it into three categories: unprocessed or minimally processed foods and process…
Eating patterns in the Brazilian Longitudinal Study of Adult Health (Elsa-Brasil): An Exploratory Analysis
The food consumption of 15,071 public employees was analyzed in six Brazilian cities participating in the baseline for Brazilian Longitudinal Study of Adult Health (ELSA-Brasil, 2008-2010) with the aim of identifying eating patterns and their relationship to socio-demographic variables. Multiple correspondence and cluster analysis were applied. Four patterns were identified, with their respective frequencies: "traditional" (48%); "fruits and vege…
Delineamento e implementacao do biobanco do Elsa-Brasil: Estudo prospectivo na populacao brasileira
O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é uma coorte prospectiva multicêntrica de funcionários públicos delineada para avaliar os determinantes das doenças crônicas, principalmente a doença cardiovascular e o diabetes tipo 2. Neste artigo são descritos os principais pontos do delineamento e implementação do projeto do biobanco do ELSA-Brasil. São detalhados aspectos econômicos, políticos, logísticos e tecnológicos do estudo. O arti…
The influence of the day of the week of hospital admission on the prognosis of stroke patients
This study aimed to evaluate the weekday and weekend distribution of stroke case hospital admissions and their respective prognosis based on a sample from the Estudo de Mortalidade e Morbidade do Acidente Vascular Cerebral (EMMA), a cohort of stroke patients admitted to a community hospital in the city of São Paulo, Brazil. We ascertained all consecutive cases of first-time strokes between April 2006 and December 2008 and performed a subsequent o…
Sunshine and suicide at the tropic of Capricorn, São Paulo, Brazil, 1996-2004
Several studies have confirmed seasonal variation in suicide rates according to hours of sunshine. The suicide pattern was assessed in São Paulo, southeastern Brazil, at the tropic of Capricorn from 1996 to 2004. Poisson regression was employed to estimate parameters of seasonality, as well as to verify associations for each day between daylight duration and suicide. During the nine-year study period, there were 3,984 suicides (76.9% in men; medi…
Raca e mortalidade cerebrovascular no Brasil
Sendo desconhecidas as taxas de mortalidade cerebrovascular segundo raça no Brasil, foram coletadas informações de óbitos de 2010 do Sistema de Informação de Mortalidade do Ministério da Saúde. Foram calculadas as taxas de mortalidade cerebrovascular, ajustadas por idade (por 100 mil), com intervalo de confiança de 95%, por sexo e raça/cor de pele. A diferença entre brancos, pardos e negros foi significativa para homens, com taxas, respectivament…
Sunshine and suicide at the tropic of Capricorn, São Paulo, Brazil, 1996-2004
Several studies have confirmed seasonal variation in suicide rates according to hours of sunshine. The suicide pattern was assessed in São Paulo, southeastern Brazil, at the tropic of Capricorn from 1996 to 2004. Poisson regression was employed to estimate parameters of seasonality, as well as to verify associations for each day between daylight duration and suicide. During the nine-year study period, there were 3,984 suicides (76.9% in men; medi…
Subclinical hyperthyroidism and dementia: The Sao Paulo Ageing & Health Study (SPAH)
The results suggest a consistent association among people with subclinical hyperthyroidism and dementia
Controle da hipertensão arterial e fatores associados na atenção primária em Unidades Básicas de Saúde localizadas na Região Oeste da cidade de São Paulo
Realizou-se estudo para caracterizar o controle de hipertensos atendidos na atenção primária com amostra de 440 hipertensos. Os hipertensos foram entrevistados e a medida da pressão foi realizada com aparelho automático validado. A relação entre as variáveis classificatórias foi avaliada com o teste qui-quadrado e posterior análise multivariada. Os resultados mostraram que o controle da hipertensão arterial foi de 45,5% e se associou (p
Prevalence of thyroid disorders among older people: Results from the São Paulo Ageing & Health Study
This study aimed to estimate prevalence of thyroid disorders in the São Paulo Ageing & Health Study, an epidemiological study addressing several health-adverse outcomes among elderly people living in a poor area of São Paulo, Brazil. All participants answered a questionnaire and had a blood sample collected to assess levels of tireotropic hormone and free-thyroxine. Among 1,373 people (60.8% women), prevalence rates (95% confidence interval) for …
Brazilian Longitudinal Study of Adult Health (Elsa-Brasil): Objectives and Design
Although low- and middle-income countries still bear the burden of major infectious diseases, chronic noncommunicable diseases are becoming increasingly common due to rapid demographic, epidemiologic, and nutritional transitions. However, information is generally scant in these countries regarding chronic disease incidence, social determinants, and risk factors. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute rel…
Doenças crônicas não transmissíveis no Brasil: Prioridade para enfrentamento e investigação
As Doenças Crônicas Não Transmissíveis representam a maior carga de morbimortalidade no Brasil. Em 2011, o Ministério da Saúde lançou seu Plano de Ações Estratégicas para o Enfrentamento das Doenças Crônicas Não Transmissíveis, enfatizando ações populacionais para controlar as doenças cardiovasculares, diabetes, câncer e doença respiratória crônica, predominantemente pelo controle do fumo, inatividade física, alimentação inadequada e uso prejudic…
Educational levels and the functional dependence of ischemic stroke survivors
We evaluated the functional dependence of stroke survivors from the Study of Stroke Mortality and Morbidity, using the Rankin Scale. Out of 355 ischemic stroke survivors (with a mean age of 67.9 years), 40% had some functional dependence at 28 days and 34.4% had some functional dependence at 6 months. Most predictors of physical dependence were identified at 28 days. These predictors were: low levels of education [illiterate vs. > 8 years of educ…
Rotinas de organizacao de exames e entrevistas no centro de investigacao Elsa-Brasil
O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é um estudo de coorte prospectivo com avaliações abrangentes ao longo do tempo. O artigo descreve a rotina de exames e entrevistas realizados pelo participante, assim como a estruturação da área física e da equipe dos Centros de Pesquisa. O ELSA-Brasil pressupõe o comparecimento do participante ao Centro de Pesquisa para a realização dos exames e entrevistas segundo protocolos padronizados de…
Afericoes e exames clinicos realizados nos participantes do Elsa-Brasil
Este artigo descreve os exames clínicos realizados no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Alguns deles (antropometria, pressão arterial e índice tornozelo-braquial) já têm uso clínico consolidado. Outros, como a velocidade de onda de pulso, variabilidade da frequência cardíaca e medida da espessura médio-intimal de carótidas, carecem de valor de referência na população brasileira não doente e podem constituir preditores importan…
Delineamento e implementacao do biobanco do Elsa-Brasil: Estudo prospectivo na populacao brasileira
O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é uma coorte prospectiva multicêntrica de funcionários públicos delineada para avaliar os determinantes das doenças crônicas, principalmente a doença cardiovascular e o diabetes tipo 2. Neste artigo são descritos os principais pontos do delineamento e implementação do projeto do biobanco do ELSA-Brasil. São detalhados aspectos econômicos, políticos, logísticos e tecnológicos do estudo. O arti…
Questionario do Elsa-Brasil: Desafios na elaboracao de instrumento multidimensional
O artigo apresenta o processo de elaboração do questionário utilizado no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Iniciamos pelo relato sobre a "Seleção de Temas" abordados no questionário, cujo conteúdo teria que abranger o conhecimento disponível acerca da complexa rede de causalidade dos desfechos de interesse, assim como possibilitar a comparabilidade com estudos semelhantes. Contextualizamos a "tradução e a adaptação de instrume…
Logistica de coleta e transporte de material biologico e organizacao do laboratorio central no Elsa-Brasil
O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é um estudo de coorte multicêntrico com o objetivo de identificar os fatores de risco associados ao diabetes tipo 2 e à doença cardiovascular na população brasileira. O artigo descreve as estratégias de coleta, processamento, transporte e de controle de qualidade dos exames de sangue e urina no ELSA. O estudo optou pela centralização dos exames em um único laboratório. O processamento das amo…
Raca e mortalidade cerebrovascular no Brasil
Sendo desconhecidas as taxas de mortalidade cerebrovascular segundo raça no Brasil, foram coletadas informações de óbitos de 2010 do Sistema de Informação de Mortalidade do Ministério da Saúde. Foram calculadas as taxas de mortalidade cerebrovascular, ajustadas por idade (por 100 mil), com intervalo de confiança de 95%, por sexo e raça/cor de pele. A diferença entre brancos, pardos e negros foi significativa para homens, com taxas, respectivament…
The influence of the day of the week of hospital admission on the prognosis of stroke patients
This study aimed to evaluate the weekday and weekend distribution of stroke case hospital admissions and their respective prognosis based on a sample from the Estudo de Mortalidade e Morbidade do Acidente Vascular Cerebral (EMMA), a cohort of stroke patients admitted to a community hospital in the city of São Paulo, Brazil. We ascertained all consecutive cases of first-time strokes between April 2006 and December 2008 and performed a subsequent o…
Reprodutibilidade e validade relativa do Questionário de Frequência Alimentar do Elsa-Brasil
Avaliou-se a reprodutibilidade e a validade do Questionário de Frequência Alimentar (QFA) utilizado no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Foram aplicados três registros alimentares e um QFA em dois momentos no período de um ano (n = 281). Valores de energia e nutrientes dos registros alimentares foram deatenuados e Log transformados. Para avaliação da reprodutibilidade e validade foi aplicado o teste de correlação intraclasse (…
Negative life events and migraine: A cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (Elsa-Brasil) baseline data
The occurrence of financial hardship and hospitalization had a direct and independent association with migraine diagnosis and frequency. The death of a close relative was also independently associated with the highest migraine frequency stratum
Global, regional, and national disability-adjusted life years (Dalys) for 306 diseases and injuries and healthy life expectancy (Hale) for 188 countries, 1990–2013: Quantifying the epidemiological tra…
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: A systematic analysis for the Global …
Cohort Profile: Longitudinal Study of Adult Health (Elsa-Brasil)
Chronic diseases are a global problem, yet information on their determinants is generally scant in low- and middle-income countries. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute relevant information regarding the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular diseases and diabetes, in one such setting. At Visit 1, we enrolled 15 105 civil servants from pre…
Associations of life course socioeconomic position and job stress with carotid intima-media thickness. The Brazilian Longitudinal Study of Adult Health (Elsa-Brasil)
Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: A systematic analysis for the Global Burden of Disease Study 2015
BACKGROUND: Established in 2000, Millennium Development Goal 4 (MDG4) catalysed extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds between 1990 and 2015. At the country level, the pace of progress in improving child survival has varied markedly, highlighting a crucial need to further examine potential drivers of accelerated or slowed decreases in child mortality. The Global Burden of Disease 2015 …
Global, regional, and national disability-adjusted life-years (Dalys) for 315 diseases and injuries and healthy life expectancy (Hale), 1990–2015: A systematic analysis for the Global Burden of Diseas…
BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE and DALYs for geographies worldwide and evaluate ho…
Global, regional, and national levels of maternal mortality, 1990–2015: A systematic analysis for the Global Burden of Disease Study 2015
BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame policy discussions. We aimed to quantify maternal mortality throughout the world by underlying cause and age from 1990 to 2015. METHODS: We estimated maternal mortality at the global, regional, …
Measuring the health-related Sustainable Development Goals in 188 countries: A baseline analysis from the Global Burden of Disease Study 2015
BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015). METHODS: We applied statistical methods to systematically compiled data to estimate the performance of…
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: A systematic analysis for the Global Burden of Disease Study 2015
BACKGROUND: Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns bas…
Medicine (89 works) · Environmental health (68 works) · Population (46 works) · Demography (44 works) · Disease (40 works) · Burden of disease (39 works) · Internal Medicine (29 works) · Disease burden (26 works) · Internal Medicine (22 works) · Global Maternal and Child Health (21 works)