D P Strachan
Biographic Data
| ID | 1520913 |
|---|---|
| NAME | D P Strachan |
| GIVEN NAMES | D P |
| FAMILY NAME | Strachan |
| SIGNATURE | STRACHAN D P |
| AFFILIATIONS | St George's, University of London |
| ORCID | 0000-0001-7854-1366 |
| VERIFIED | Yes |
| TOTAL WORKS | 20 |
| TOTAL CITATIONS | 87 |
| WORKS AS AUTHOR | 20 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1989 |
| LATEST PUBLICATION YEAR | 2012 |
| H-INDEX | 5 |
The Carpow Bronze Age Logboat
P2-321 The relationship between BMI and wheezing in the international study of asthma and allergies in childhood phase 2
Introduction An inflammatory link and common genetic factors have been discussed regarding the relation between BMI and asthma. We investigated the relation between obesity and asthma symptoms, and effect modification by atopy and parental allergic disease in Phase 2 of the International Study of Asthma and Allergies in Childhood. Methods In a population-based cross-sectional study, 10 600 children aged 8–12 from 22 centres worldwide were studied…
Loss and representativeness in a biomedical survey at age 45 years
OBJECTIVE: A biomedical survey of the 1958 British birth cohort at age 45 years provides a baseline for future studies of chronic disease. The extent and nature of bias in this sample was examined. METHODS: Follow-up of all births in Great Britain in one week in March 1958. At 45 years the sample was compared with the surviving cohort on characteristics recorded at birth and seven years, and in adulthood (42 years). RESULTS: Sample attrition to a…
Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood
Lung Function and Cognitive Ability in a Longitudinal Birth Cohort Study
OBJECTIVE: The objective of this study was to examine the association between forced expiratory volume in 1 second (FEV1) and cognitive ability in midlife in the normal population. METHODS: Multiple regression was used to test associations between FEV1 and cognitive function in 1778 men and women in the MRC National Survey of Health and Development, also known as the British 1946 birth cohort. Analyses were adjusted for sex, body size (birth weig…
Epidemiology of Epstein-Barr virus infection in pre-adolescent children
STUDY OBJECTIVE: To describe the epidemiology of Epstein-Barr virus (EBV) among primary school children by testing saliva with a new EBV capsid antigen "G" antibody capture radioimmunoassay (GACRIA). DESIGN: A population based sample of 7 year old schoolchildren were followed up at age 11. SETTING: 30 randomly chosen primary schools in Edinburgh, Scotland. PARTICIPANTS: 552 schoolchildren. MEASUREMENTS: Data on risk factors for infection were col…
Systematic identification of twins by computerised searches of NHS patient registers in the UK
OBJECTIVES: This study aimed to assess the feasibility, sensitivity, and specificity of a systematic search of the NHS central register for twins of the same sex. DESIGN, SETTING, AND SUBJECTS: Computerised searches by alphanumeric NHS number, sex, and date of birth of 1.6 million patients registered with general practitioners in Kent, followed by validation by postal questionnaire sent to 66 pairs of children, 129 pairs of adult twins, and one s…
Socioeconomic deprivation, ethnicity, and stroke mortality in Greater London and south east England
OBJECTIVE AND SETTING: To examine geographical variation in stroke mortality in Greater London compared with the surrounding South East Region of England. DESIGN: Cross sectional, ecological analysis based on electoral wards. SUBJECTS: Resident population aged 45 years or more. MAIN OUTCOME MEASURE: Age specific stroke mortality rates in five age bands, 1986-92. MAIN OUTCOME MEASURE: Age specific stroke mortality rates in five age bands, 1986-92.…
Trends in stroke mortality in Greater London and south east England--evidence for a cohort effect
OBJECTIVE AND SETTING: To examine time trends in stroke mortality in Greater London compared with the surrounding South East Region of England. DESIGN: Age-cohort analysis based on routine mortality data. SUBJECTS: Resident population aged 45 years or more. MAIN OUTCOME MEASURE: Age specific stroke mortality rates, 1951-92. MAIN RESULTS: In 1951, stroke mortality was lower in Greater London than the surrounding South East Region in all age bands …
Effects of air pollution on daily hospital admissions for respiratory disease in London between 1987-88 and 1991-92
STUDY OBJECTIVE: To investigate whether air pollution levels in London have short term effects on hospital admissions for respiratory disease. DESIGN: Poisson regression analysis of daily counts of hospital admissions, adjusting for effects of trend, seasonal and other cyclical factors, day of the week, holidays, influenza epidemic, temperature, humidity, and autocorrelation. Pollution variables were particulates (black smoke: BS), sulphur dioxid…
Adult height and mortality in London
STUDY OBJECTIVE--To examine in detail the cause specific associations between height and mortality. DESIGN--A prospective cohort study with an 18 year mortality follow up. SETTING AND PARTICIPANTS--The Whitehall study of 18,403 men in the civil service in London examined between 1967 and 1969 aged 40-64 and followed up for mortality until the end of January 1987. MAIN RESULTS--There was considerable variation in the strength of height-mortality a…
Environmental Tobacco Smoke and Mortality
Socioeconomic Characteristics of Interregional Migrants in England and Wales, 1939-71
Data from the Longitudinal Study (LS) of the Office of Population Censuses and Surveys are used to examine patterns of regional migration in England and Wales between 1939 and 1971. The source of information on region in 1939 is from a national population register established shortly after the start of the Second World War. Of the 146 444 women and 129 267 men in the LS born before the register was established, 83.5% of the women and 50.1% of the…
Ventilatory function, height, and mortality among lifelong non-smokers
STUDY OBJECTIVE--The aims were to determine the relationship between spirometric indices and mortality among lifelong non-smokers, and to investigate whether the association of short stature with increased risk of death is explained by reduced levels of ventilatory function in shorter men. DESIGN--The study was a nested (within cohort) case-control analysis of an 18 year prospective study of mortality. SUBJECTS--Participants were 3452 male civil …
Causes and control of chronic respiratory disease
Causes and control of chronic respiratory disease: looking beyond the smokescreen Cigarette smoking is as strongly related to death from chronic bronchitis and emphysema as it is to mortality from lung cancer.' Symptoms of cough, phlegm, wheeze, and breathlessness are also much more common among individuals on August 14, 2023 by guest
Determinants of passive smoking in children in Edinburgh, Scotland
OBJECTIVES. Using saliva cotinine as a quantitative marker, we examined the contribution of factors other than parental smoking to children's passive exposure to tobacco smoke. METHODS. Saliva specimens from a random sample of 734 7-year-old schoolchildren in Edinburgh, Scotland, were analyzed for cotinine. Their parents completed a questionnaire covering smoking habits and conditions in the home. RESULTS. A number of independent predictors of co…
Regional variations in wheezing illness in British children
STUDY OBJECTIVE--The aim was to examine the regional distribution of wheezing illness among British children, and the age at which geographical differences may be determined. DESIGN--Cross sectional analyses and study of interregional migrants were used. SUBJECTS--The subjects were national cohorts of British children born in 1958 and 1970. MEASUREMENTS AND MAIN RESULTS--The regional distribution of wheezing illness showed significant heterogenei…
Hay fever, hygiene, and household size.
chemical findings stable.The packed cell volume was 0 27.With hypertonic peritoneal dialysis his weight decreased by 1 6 kg, but blood pressure remained raised at 230/130 mm Hg, and the next day he suffered two generalised seizures.Packed cell volume was 0-35.Phenytoin was started.He was discharged on 17 December, normotensive with no neurological sequelae, and taking no antihypertensive medication.Phenytoin was subsequently withdrawn.He had a ca…
Making sense of data. A self-instructed manual of epidemiological data
The foreword describes this book as "about concepts and methods of surveillance in health care".It does this very competently, in breadth and depth, in both general principles and practical applications.The general aspects include a history of surveillance, indicators, action and benefit, and ethical dilemmas.The book covers surveillance from hospital and primary care data, examines surveillance ofcongenital malformations and the perinatal period…
Damp housing and childhood asthma; respiratory effects of indoor air temperature and relative humidity
In a questionnaire survey of a random sample of 1000 children aged 7 years, a significantly greater proportion of those living in homes reported as damp were affected by wheeze (22% v 11%), day cough, night cough, and chesty colds. Simultaneous estimation of relative humidity in the bedrooms of 778 children and continuous 7 day recordings of ambient temperature and humidity in a stratified sample of 317 bedrooms showed no association with the sam…
Adult height and mortality in London
STUDY OBJECTIVE--To examine in detail the cause specific associations between height and mortality. DESIGN--A prospective cohort study with an 18 year mortality follow up. SETTING AND PARTICIPANTS--The Whitehall study of 18,403 men in the civil service in London examined between 1967 and 1969 aged 40-64 and followed up for mortality until the end of January 1987. MAIN RESULTS--There was considerable variation in the strength of height-mortality a…
Loss and representativeness in a biomedical survey at age 45 years
OBJECTIVE: A biomedical survey of the 1958 British birth cohort at age 45 years provides a baseline for future studies of chronic disease. The extent and nature of bias in this sample was examined. METHODS: Follow-up of all births in Great Britain in one week in March 1958. At 45 years the sample was compared with the surviving cohort on characteristics recorded at birth and seven years, and in adulthood (42 years). RESULTS: Sample attrition to a…
Damp housing and childhood asthma; respiratory effects of indoor air temperature and relative humidity
In a questionnaire survey of a random sample of 1000 children aged 7 years, a significantly greater proportion of those living in homes reported as damp were affected by wheeze (22% v 11%), day cough, night cough, and chesty colds. Simultaneous estimation of relative humidity in the bedrooms of 778 children and continuous 7 day recordings of ambient temperature and humidity in a stratified sample of 317 bedrooms showed no association with the sam…
Effects of air pollution on daily hospital admissions for respiratory disease in London between 1987-88 and 1991-92
STUDY OBJECTIVE: To investigate whether air pollution levels in London have short term effects on hospital admissions for respiratory disease. DESIGN: Poisson regression analysis of daily counts of hospital admissions, adjusting for effects of trend, seasonal and other cyclical factors, day of the week, holidays, influenza epidemic, temperature, humidity, and autocorrelation. Pollution variables were particulates (black smoke: BS), sulphur dioxid…
Determinants of passive smoking in children in Edinburgh, Scotland
OBJECTIVES. Using saliva cotinine as a quantitative marker, we examined the contribution of factors other than parental smoking to children's passive exposure to tobacco smoke. METHODS. Saliva specimens from a random sample of 734 7-year-old schoolchildren in Edinburgh, Scotland, were analyzed for cotinine. Their parents completed a questionnaire covering smoking habits and conditions in the home. RESULTS. A number of independent predictors of co…
Socioeconomic Characteristics of Interregional Migrants in England and Wales, 1939-71
Data from the Longitudinal Study (LS) of the Office of Population Censuses and Surveys are used to examine patterns of regional migration in England and Wales between 1939 and 1971. The source of information on region in 1939 is from a national population register established shortly after the start of the Second World War. Of the 146 444 women and 129 267 men in the LS born before the register was established, 83.5% of the women and 50.1% of the…
Socioeconomic deprivation, ethnicity, and stroke mortality in Greater London and south east England
OBJECTIVE AND SETTING: To examine geographical variation in stroke mortality in Greater London compared with the surrounding South East Region of England. DESIGN: Cross sectional, ecological analysis based on electoral wards. SUBJECTS: Resident population aged 45 years or more. MAIN OUTCOME MEASURE: Age specific stroke mortality rates in five age bands, 1986-92. MAIN OUTCOME MEASURE: Age specific stroke mortality rates in five age bands, 1986-92.…
Ventilatory function, height, and mortality among lifelong non-smokers
STUDY OBJECTIVE--The aims were to determine the relationship between spirometric indices and mortality among lifelong non-smokers, and to investigate whether the association of short stature with increased risk of death is explained by reduced levels of ventilatory function in shorter men. DESIGN--The study was a nested (within cohort) case-control analysis of an 18 year prospective study of mortality. SUBJECTS--Participants were 3452 male civil …
Regional variations in wheezing illness in British children
STUDY OBJECTIVE--The aim was to examine the regional distribution of wheezing illness among British children, and the age at which geographical differences may be determined. DESIGN--Cross sectional analyses and study of interregional migrants were used. SUBJECTS--The subjects were national cohorts of British children born in 1958 and 1970. MEASUREMENTS AND MAIN RESULTS--The regional distribution of wheezing illness showed significant heterogenei…
Hay fever, hygiene, and household size.
chemical findings stable.The packed cell volume was 0 27.With hypertonic peritoneal dialysis his weight decreased by 1 6 kg, but blood pressure remained raised at 230/130 mm Hg, and the next day he suffered two generalised seizures.Packed cell volume was 0-35.Phenytoin was started.He was discharged on 17 December, normotensive with no neurological sequelae, and taking no antihypertensive medication.Phenytoin was subsequently withdrawn.He had a ca…
Making sense of data. A self-instructed manual of epidemiological data
The foreword describes this book as "about concepts and methods of surveillance in health care".It does this very competently, in breadth and depth, in both general principles and practical applications.The general aspects include a history of surveillance, indicators, action and benefit, and ethical dilemmas.The book covers surveillance from hospital and primary care data, examines surveillance ofcongenital malformations and the perinatal period…
Damp housing and childhood asthma; respiratory effects of indoor air temperature and relative humidity
In a questionnaire survey of a random sample of 1000 children aged 7 years, a significantly greater proportion of those living in homes reported as damp were affected by wheeze (22% v 11%), day cough, night cough, and chesty colds. Simultaneous estimation of relative humidity in the bedrooms of 778 children and continuous 7 day recordings of ambient temperature and humidity in a stratified sample of 317 bedrooms showed no association with the sam…
Regional variations in wheezing illness in British children
STUDY OBJECTIVE--The aim was to examine the regional distribution of wheezing illness among British children, and the age at which geographical differences may be determined. DESIGN--Cross sectional analyses and study of interregional migrants were used. SUBJECTS--The subjects were national cohorts of British children born in 1958 and 1970. MEASUREMENTS AND MAIN RESULTS--The regional distribution of wheezing illness showed significant heterogenei…
Ventilatory function, height, and mortality among lifelong non-smokers
STUDY OBJECTIVE--The aims were to determine the relationship between spirometric indices and mortality among lifelong non-smokers, and to investigate whether the association of short stature with increased risk of death is explained by reduced levels of ventilatory function in shorter men. DESIGN--The study was a nested (within cohort) case-control analysis of an 18 year prospective study of mortality. SUBJECTS--Participants were 3452 male civil …
Causes and control of chronic respiratory disease
Causes and control of chronic respiratory disease: looking beyond the smokescreen Cigarette smoking is as strongly related to death from chronic bronchitis and emphysema as it is to mortality from lung cancer.' Symptoms of cough, phlegm, wheeze, and breathlessness are also much more common among individuals on August 14, 2023 by guest
Determinants of passive smoking in children in Edinburgh, Scotland
OBJECTIVES. Using saliva cotinine as a quantitative marker, we examined the contribution of factors other than parental smoking to children's passive exposure to tobacco smoke. METHODS. Saliva specimens from a random sample of 734 7-year-old schoolchildren in Edinburgh, Scotland, were analyzed for cotinine. Their parents completed a questionnaire covering smoking habits and conditions in the home. RESULTS. A number of independent predictors of co…
Environmental Tobacco Smoke and Mortality
Socioeconomic Characteristics of Interregional Migrants in England and Wales, 1939-71
Data from the Longitudinal Study (LS) of the Office of Population Censuses and Surveys are used to examine patterns of regional migration in England and Wales between 1939 and 1971. The source of information on region in 1939 is from a national population register established shortly after the start of the Second World War. Of the 146 444 women and 129 267 men in the LS born before the register was established, 83.5% of the women and 50.1% of the…
Adult height and mortality in London
STUDY OBJECTIVE--To examine in detail the cause specific associations between height and mortality. DESIGN--A prospective cohort study with an 18 year mortality follow up. SETTING AND PARTICIPANTS--The Whitehall study of 18,403 men in the civil service in London examined between 1967 and 1969 aged 40-64 and followed up for mortality until the end of January 1987. MAIN RESULTS--There was considerable variation in the strength of height-mortality a…
Effects of air pollution on daily hospital admissions for respiratory disease in London between 1987-88 and 1991-92
STUDY OBJECTIVE: To investigate whether air pollution levels in London have short term effects on hospital admissions for respiratory disease. DESIGN: Poisson regression analysis of daily counts of hospital admissions, adjusting for effects of trend, seasonal and other cyclical factors, day of the week, holidays, influenza epidemic, temperature, humidity, and autocorrelation. Pollution variables were particulates (black smoke: BS), sulphur dioxid…
Systematic identification of twins by computerised searches of NHS patient registers in the UK
OBJECTIVES: This study aimed to assess the feasibility, sensitivity, and specificity of a systematic search of the NHS central register for twins of the same sex. DESIGN, SETTING, AND SUBJECTS: Computerised searches by alphanumeric NHS number, sex, and date of birth of 1.6 million patients registered with general practitioners in Kent, followed by validation by postal questionnaire sent to 66 pairs of children, 129 pairs of adult twins, and one s…
Socioeconomic deprivation, ethnicity, and stroke mortality in Greater London and south east England
OBJECTIVE AND SETTING: To examine geographical variation in stroke mortality in Greater London compared with the surrounding South East Region of England. DESIGN: Cross sectional, ecological analysis based on electoral wards. SUBJECTS: Resident population aged 45 years or more. MAIN OUTCOME MEASURE: Age specific stroke mortality rates in five age bands, 1986-92. MAIN OUTCOME MEASURE: Age specific stroke mortality rates in five age bands, 1986-92.…
Trends in stroke mortality in Greater London and south east England--evidence for a cohort effect
OBJECTIVE AND SETTING: To examine time trends in stroke mortality in Greater London compared with the surrounding South East Region of England. DESIGN: Age-cohort analysis based on routine mortality data. SUBJECTS: Resident population aged 45 years or more. MAIN OUTCOME MEASURE: Age specific stroke mortality rates, 1951-92. MAIN RESULTS: In 1951, stroke mortality was lower in Greater London than the surrounding South East Region in all age bands …
Epidemiology of Epstein-Barr virus infection in pre-adolescent children
STUDY OBJECTIVE: To describe the epidemiology of Epstein-Barr virus (EBV) among primary school children by testing saliva with a new EBV capsid antigen "G" antibody capture radioimmunoassay (GACRIA). DESIGN: A population based sample of 7 year old schoolchildren were followed up at age 11. SETTING: 30 randomly chosen primary schools in Edinburgh, Scotland. PARTICIPANTS: 552 schoolchildren. MEASUREMENTS: Data on risk factors for infection were col…
Lung Function and Cognitive Ability in a Longitudinal Birth Cohort Study
OBJECTIVE: The objective of this study was to examine the association between forced expiratory volume in 1 second (FEV1) and cognitive ability in midlife in the normal population. METHODS: Multiple regression was used to test associations between FEV1 and cognitive function in 1778 men and women in the MRC National Survey of Health and Development, also known as the British 1946 birth cohort. Analyses were adjusted for sex, body size (birth weig…
Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood
Loss and representativeness in a biomedical survey at age 45 years
OBJECTIVE: A biomedical survey of the 1958 British birth cohort at age 45 years provides a baseline for future studies of chronic disease. The extent and nature of bias in this sample was examined. METHODS: Follow-up of all births in Great Britain in one week in March 1958. At 45 years the sample was compared with the surviving cohort on characteristics recorded at birth and seven years, and in adulthood (42 years). RESULTS: Sample attrition to a…
P2-321 The relationship between BMI and wheezing in the international study of asthma and allergies in childhood phase 2
Introduction An inflammatory link and common genetic factors have been discussed regarding the relation between BMI and asthma. We investigated the relation between obesity and asthma symptoms, and effect modification by atopy and parental allergic disease in Phase 2 of the International Study of Asthma and Allergies in Childhood. Methods In a population-based cross-sectional study, 10 600 children aged 8–12 from 22 centres worldwide were studied…
The Carpow Bronze Age Logboat
Medicine (17 works) · Demography (11 works) · Internal Medicine (11 works) · Internal Medicine (10 works) · Environmental health (9 works) · Population (9 works) · Pediatrics (7 works) · Epidemiology (6 works) · Pediatrics (6 works) · Asthma and respiratory diseases (5 works)