Samodova V Samodova
Biographic Data
| ID | 159732 |
|---|---|
| NAME | Samodova V Samodova |
| GIVEN NAMES | Samodova V |
| FAMILY NAME | Samodova |
| SIGNATURE | SAMODOVA S V |
| AFFILIATIONS | Northern (Arctic) Federal University |
| ORCID | 0000-0001-9835-8083 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 9 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2015 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Functional Characteristics of Immunoregulatory Blood Proteins in Women of Reproductive Age Residing in the European North and Arctic Regions of the Russian Federation
Aim The purpose of this study was to identify the functional characteristics of blood proteins which are important in assessing reproductive health due to their immunoregulatory effects in women residing in the European North and Arctic regions of the Russian Federation. Methods A total of 557 women aged 21–55 (36.89 ± 0.54), engaged in intellectual professions, born and long‐term residents of the European North (Arkhangelsk Oblast) and Arctic (M…
Distinctive aspects of the immune status of the Kola Saami and Russians living in the Far North
OBJECTIVE: The level of immunological reactivity of the indigenous inhabitants of the Far North may depend on the extreme-discomfort factors of the climatic environment and genetic traits of the population. Therefore, the aim of this study was to identify the distinctive elements of the immune status of the Kola Saami and Russians living in the Far North (Murmansk Region). METHODS: A complex immunological study of peripheral venous blood composit…
Features of the immune system and levels of blood transport components in residents of the arctic of the Russian Federation
Changes in the immune status and the content of blood transport components reflect adaptations in the human body in response to adverse factors, showcasing the organism's adaptive capabilities and functional state. In this study, we aimed to determine the features of the immune system and levels of transport components of the blood system in residents of the Arctic of the Russian Federation. METHODS: The peripheral venous blood of 191 residents o…
Blood concentrations of brain natriuretic peptide (Nt-pro-BNP) and the regulation of hemodynamic reactions in healthy adult Arctic residents
BACKGROUND: In previous studies, we have observed that the levels of Nt-pro-BNP in healthy individuals are lower than among patients with coronary heart disease and hypertension. Additionally, Nt-pro-BNP concentration increases with age. Interestingly, Arctic residents have higher levels of Nt-pro-BNP compared to those living in other northern territories.AIM: To study the role of Nt-pro-BNP in the regulation of hemodynamic reactions in adults re…
Assessment of metabolic activity and energy supply of peripheral blood lymphocytes
BACKGROUND: T-cells have the capability to change their metabolism in response to activation signals. Resting T-cells primarily use the oxidation of higher fatty acids and oxidative phosphorylation in mitochondria for their energy needs, whereas activated T-cells switch to aerobic glycolysis and glutaminolysis, using glucose, and glutamine as substrates, respectively. AIM: To determine the metabolic activity and energy supply of peripheral blood …
Features of immunological reactivity in Sami women
BACKGROUND: The Sami are a small group of indigenous people of the Russian Federation. The Sami have one of the lowest birth rates among all the peoples of the North of Russia. They often have more health problems than residents of other nationalities in the Murmansk region, due to a high incidence of acute respiratory infections. Extreme climatic and geographical conditions of the Arctic have a negative impact on immunological reactivity.AIM: To…
Concentrations of Peripheral Blood Lymphocytes Intracellular Metabolic Regulators in Residents of the European North of Russia
Introduction: Metabolic processes controlled by cellular signaling mechanisms influence differentiation, proliferation, functional activity, and phenotypic stability of T cells. Hypoxia-inducible factor 1 (HIF-1) is a positive regulator of glycolysis. HIF-1 can be activated by an oxygen-independent pathway through the transcriptional activator STAT3. Sirtuin-3 (SIRT3) regulates the activity of the mitochondrial processes. Aim: To determine the ch…
Peripheral Blood Lymphocytes Adenosine Triphosphate Availability Among the Residents of the Northern European Russia
Metabolic pathways participating in adenosine triphosphate (ATP) synthesis play an important role in lymphocytes normal development and functioning. Energetic metabolism has an influence on differentiation, proliferation and fate of lymphocytes. The aim of the study is to define ATP availability of peripheral blood lymphocytes and the level of mitochondrial metabolism regulator sirtuin 3 (SIRT3) in healthy northerners. Methods. 106 volunteers, ha…
Correlation of Receptors’ Extracellular Pool and Immune Response Level in Individuals Living in Arctic Conditions
The paper has presented data on the study of a relationship of activity of the immune response and the accumulation of a pool of free molecules involved in the processes of cell cooperation, activation of immune cells and their apoptosis in villagers of Revda, the Levozersky District of the Murmansk Region. The study has involved 91 people, 77 women and 14 men aged from 21 to 55 years. In order to study correlation levels of the immune response a…
Features of immunological reactivity in Sami women
BACKGROUND: The Sami are a small group of indigenous people of the Russian Federation. The Sami have one of the lowest birth rates among all the peoples of the North of Russia. They often have more health problems than residents of other nationalities in the Murmansk region, due to a high incidence of acute respiratory infections. Extreme climatic and geographical conditions of the Arctic have a negative impact on immunological reactivity.AIM: To…
Correlation of Receptors’ Extracellular Pool and Immune Response Level in Individuals Living in Arctic Conditions
The paper has presented data on the study of a relationship of activity of the immune response and the accumulation of a pool of free molecules involved in the processes of cell cooperation, activation of immune cells and their apoptosis in villagers of Revda, the Levozersky District of the Murmansk Region. The study has involved 91 people, 77 women and 14 men aged from 21 to 55 years. In order to study correlation levels of the immune response a…
Peripheral Blood Lymphocytes Adenosine Triphosphate Availability Among the Residents of the Northern European Russia
Metabolic pathways participating in adenosine triphosphate (ATP) synthesis play an important role in lymphocytes normal development and functioning. Energetic metabolism has an influence on differentiation, proliferation and fate of lymphocytes. The aim of the study is to define ATP availability of peripheral blood lymphocytes and the level of mitochondrial metabolism regulator sirtuin 3 (SIRT3) in healthy northerners. Methods. 106 volunteers, ha…
Concentrations of Peripheral Blood Lymphocytes Intracellular Metabolic Regulators in Residents of the European North of Russia
Introduction: Metabolic processes controlled by cellular signaling mechanisms influence differentiation, proliferation, functional activity, and phenotypic stability of T cells. Hypoxia-inducible factor 1 (HIF-1) is a positive regulator of glycolysis. HIF-1 can be activated by an oxygen-independent pathway through the transcriptional activator STAT3. Sirtuin-3 (SIRT3) regulates the activity of the mitochondrial processes. Aim: To determine the ch…
Assessment of metabolic activity and energy supply of peripheral blood lymphocytes
BACKGROUND: T-cells have the capability to change their metabolism in response to activation signals. Resting T-cells primarily use the oxidation of higher fatty acids and oxidative phosphorylation in mitochondria for their energy needs, whereas activated T-cells switch to aerobic glycolysis and glutaminolysis, using glucose, and glutamine as substrates, respectively. AIM: To determine the metabolic activity and energy supply of peripheral blood …
Features of immunological reactivity in Sami women
BACKGROUND: The Sami are a small group of indigenous people of the Russian Federation. The Sami have one of the lowest birth rates among all the peoples of the North of Russia. They often have more health problems than residents of other nationalities in the Murmansk region, due to a high incidence of acute respiratory infections. Extreme climatic and geographical conditions of the Arctic have a negative impact on immunological reactivity.AIM: To…
Blood concentrations of brain natriuretic peptide (Nt-pro-BNP) and the regulation of hemodynamic reactions in healthy adult Arctic residents
BACKGROUND: In previous studies, we have observed that the levels of Nt-pro-BNP in healthy individuals are lower than among patients with coronary heart disease and hypertension. Additionally, Nt-pro-BNP concentration increases with age. Interestingly, Arctic residents have higher levels of Nt-pro-BNP compared to those living in other northern territories.AIM: To study the role of Nt-pro-BNP in the regulation of hemodynamic reactions in adults re…
Distinctive aspects of the immune status of the Kola Saami and Russians living in the Far North
OBJECTIVE: The level of immunological reactivity of the indigenous inhabitants of the Far North may depend on the extreme-discomfort factors of the climatic environment and genetic traits of the population. Therefore, the aim of this study was to identify the distinctive elements of the immune status of the Kola Saami and Russians living in the Far North (Murmansk Region). METHODS: A complex immunological study of peripheral venous blood composit…
Features of the immune system and levels of blood transport components in residents of the arctic of the Russian Federation
Changes in the immune status and the content of blood transport components reflect adaptations in the human body in response to adverse factors, showcasing the organism's adaptive capabilities and functional state. In this study, we aimed to determine the features of the immune system and levels of transport components of the blood system in residents of the Arctic of the Russian Federation. METHODS: The peripheral venous blood of 191 residents o…
Functional Characteristics of Immunoregulatory Blood Proteins in Women of Reproductive Age Residing in the European North and Arctic Regions of the Russian Federation
Aim The purpose of this study was to identify the functional characteristics of blood proteins which are important in assessing reproductive health due to their immunoregulatory effects in women residing in the European North and Arctic regions of the Russian Federation. Methods A total of 557 women aged 21–55 (36.89 ± 0.54), engaged in intellectual professions, born and long‐term residents of the European North (Arkhangelsk Oblast) and Arctic (M…
Immunology (7 works) · Biology (6 works) · Medicine (6 works) · Immune system (5 works) · Biochemistry (4 works) · CD8 (4 works) · Endocrinology (4 works) · Internal Medicine (4 works) · Antibody (3 works) · Cell Biology (3 works)