J André Knottnerus
Biographic Data
| ID | 2144424 |
|---|---|
| NAME | J André Knottnerus |
| GIVEN NAMES | J André |
| FAMILY NAME | Knottnerus |
| SIGNATURE | KNOTTNERUS J A |
| AFFILIATIONS | Maastricht University |
| ORCID | 0000-0001-8159-4696 |
| VERIFIED | Yes |
| TOTAL WORKS | 14 |
| TOTAL CITATIONS | 5 |
| AUTHOR COUNT | 14 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1996 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 1 |
Cannabis policy in The Netherlands: Rationale and design of an experiment with a controlled legal (‘closed’) cannabis supply chain
Since the Dutch tolerance policy, allowing the purchase of cannabis in 'coffeeshops', is associated with problems of public order and safety as well as health risks, there has been a long debate about legalisation of cannabis production and supply. It was therefore decided to conduct an experiment with a controlled legal ('closed') cannabis supply chain for recreational use. This is of international relevance in view of the current illegal cannab…
Magnitude and determinants of multimorbidity and health care utilization among patients attending public versus private primary care: A cross-sectional study from Odisha, India
Our findings suggest that, multimorbidity is being more reported in public primary care facilities. The pattern and health care utilization in both types of settings are different. A comprehensive care approach must be designed for private care providers
Towards a ‘patient-centred’ operationalisation of the new dynamic concept of health: A mixed methods study
OBJECTIVE: To evaluate among stakeholders the support for the new, dynamic concept of health, as published in 2011: 'Health as the ability to adapt and to self-manage', and to elaborate perceived indicators of health in order to make the concept measurable. DESIGN: A mixed methods study: a qualitative first step with interviews and focus groups, followed by a quantitative survey. PARTICIPANTS: Representatives of seven healthcare stakeholder domai…
How should we define health?
The WHO definition of health as complete wellbeing is no longer fit for purpose given the rise of chronic disease. Machteld Huber and colleagues propose changing the emphasis towards the ability to adapt and self manage in the face of social, physical, and emotional challenges
Alcohol intake and cardiovascular disease and mortality: The role of pre-existing disease
Objectives: Pre-existing conditions have been postulated as possible causes of the J-shaped relationship between alcohol intake and cardiovascular disease. Two research questions have been addressed in this paper. First, whether never drinkers and former drinkers differ from moderate drinkers in terms of health, and if so, which health problems contribute to this difference. Second, whether the U-shaped relationship between current alcohol intake…
Does a competitive voucher program for adolescents improve the quality of reproductive health care? A simulated patient study in Nicaragua
This study illustrates provider-related obstacles adolescents often face when requesting contraception. The care provided during the voucher program improved for some important outcomes. The improvements were more pronounced among providers with the weakest initial performance. Shared decision-making and condom promotion were improvements that sustained after the program ended. The SP method is suitable and relatively easy to apply in monitoring …
Development of the chronic fatigue syndrome in severely fatigued employees: Predictors of outcome in the Maastricht cohort study
Study objective: To identify risk factors of the development of the chronic fatigue syndrome (CFS), the persistence or recurrence of fatigue, or recovery from fatigue in a large sample of fatigued employees. Design: Analyses were based on the Maastricht cohort study (MCS), a prospective population based cohort study among more than 12 000 employees. Multiple regression models were used to identify predictors of CFS-like caseness (meeting research…
Alvan R Feinstein
Drawing from an inexhaustible source of clinical expertise, clinical research, and intellectual creativity, Alvan R Feinstein (1925–2001) became the founding father of clinical epidemiology. He was
Challenges in dia-prognostic research
The relevance of design issues and new methods It is sad to comment on work of a founding father of clinical epidemiology, who so profoundly enjoyed the scientific debate, without him being able to respond. But it is not only sad, it is also a great honour to have the opportunity to discuss one of the last pieces of this great architect of clinical research.1 The points made by Alvan Feinstein are clear and I agree with most of his analysis, but …
Marginal impact of psychosocial factors on multimorbidity: Results of an Explorative Nested Case-Control Study
Flexible work schedules and mental and physical health. A study of a working population with non-traditional working hours
The relationship between health complaints and flexible work schedules was studied in a patient population selected by general practitioners. Four hundred and eighty patients between 20 and 60 years, currently employed or on sick leave, completed questionnaires which compiled data on their work situation, subjective physical health, psychological well-being, and quality of sleep. Subjective health measurements were performed by using the 21-item …
Multimorbidity in General Practice: Prevalence, Incidence, and Determinants of Co-Occurring Chronic and Recurrent Diseases
Economic evaluation of cholesterol-related interventions in general practice. An appraisal of the evidence
STUDY OBJECTIVE: To investigate and evaluate published data on cost effectiveness of cholesterol lowering interventions, and how this information could be interpreted in a rational approach of cholesterol management in general practice. DESIGN: A systematic review of the literature. SETTING: No restriction on setting. MATERIALS: Papers reporting on the cost effectiveness or cost utility of prevention of (recurrent) coronary heart disease by reduc…
Comorbidity or multimorbidity: What's in a name? A review of literature
Aim: Comorbidity is increasingly prevalent. Moreover, many different definitions and interpretations of this phenomenon are used. Because of its social and clinical significance, it is important that the concept is clear. In this review a summary of current uses of this concept and relevant figures are given, as well as a proposal for future use.Method: A computerised search and an additional literature search were performed to identify relevant …
Marginal impact of psychosocial factors on multimorbidity: Results of an Explorative Nested Case-Control Study
Challenges in dia-prognostic research
The relevance of design issues and new methods It is sad to comment on work of a founding father of clinical epidemiology, who so profoundly enjoyed the scientific debate, without him being able to respond. But it is not only sad, it is also a great honour to have the opportunity to discuss one of the last pieces of this great architect of clinical research.1 The points made by Alvan Feinstein are clear and I agree with most of his analysis, but …
Comorbidity or multimorbidity: What's in a name? A review of literature
Aim: Comorbidity is increasingly prevalent. Moreover, many different definitions and interpretations of this phenomenon are used. Because of its social and clinical significance, it is important that the concept is clear. In this review a summary of current uses of this concept and relevant figures are given, as well as a proposal for future use.Method: A computerised search and an additional literature search were performed to identify relevant …
Multimorbidity in General Practice: Prevalence, Incidence, and Determinants of Co-Occurring Chronic and Recurrent Diseases
Economic evaluation of cholesterol-related interventions in general practice. An appraisal of the evidence
STUDY OBJECTIVE: To investigate and evaluate published data on cost effectiveness of cholesterol lowering interventions, and how this information could be interpreted in a rational approach of cholesterol management in general practice. DESIGN: A systematic review of the literature. SETTING: No restriction on setting. MATERIALS: Papers reporting on the cost effectiveness or cost utility of prevention of (recurrent) coronary heart disease by reduc…
Flexible work schedules and mental and physical health. A study of a working population with non-traditional working hours
The relationship between health complaints and flexible work schedules was studied in a patient population selected by general practitioners. Four hundred and eighty patients between 20 and 60 years, currently employed or on sick leave, completed questionnaires which compiled data on their work situation, subjective physical health, psychological well-being, and quality of sleep. Subjective health measurements were performed by using the 21-item …
Marginal impact of psychosocial factors on multimorbidity: Results of an Explorative Nested Case-Control Study
Alvan R Feinstein
Drawing from an inexhaustible source of clinical expertise, clinical research, and intellectual creativity, Alvan R Feinstein (1925–2001) became the founding father of clinical epidemiology. He was
Challenges in dia-prognostic research
The relevance of design issues and new methods It is sad to comment on work of a founding father of clinical epidemiology, who so profoundly enjoyed the scientific debate, without him being able to respond. But it is not only sad, it is also a great honour to have the opportunity to discuss one of the last pieces of this great architect of clinical research.1 The points made by Alvan Feinstein are clear and I agree with most of his analysis, but …
Development of the chronic fatigue syndrome in severely fatigued employees: Predictors of outcome in the Maastricht cohort study
Study objective: To identify risk factors of the development of the chronic fatigue syndrome (CFS), the persistence or recurrence of fatigue, or recovery from fatigue in a large sample of fatigued employees. Design: Analyses were based on the Maastricht cohort study (MCS), a prospective population based cohort study among more than 12 000 employees. Multiple regression models were used to identify predictors of CFS-like caseness (meeting research…
Does a competitive voucher program for adolescents improve the quality of reproductive health care? A simulated patient study in Nicaragua
This study illustrates provider-related obstacles adolescents often face when requesting contraception. The care provided during the voucher program improved for some important outcomes. The improvements were more pronounced among providers with the weakest initial performance. Shared decision-making and condom promotion were improvements that sustained after the program ended. The SP method is suitable and relatively easy to apply in monitoring …
Alcohol intake and cardiovascular disease and mortality: The role of pre-existing disease
Objectives: Pre-existing conditions have been postulated as possible causes of the J-shaped relationship between alcohol intake and cardiovascular disease. Two research questions have been addressed in this paper. First, whether never drinkers and former drinkers differ from moderate drinkers in terms of health, and if so, which health problems contribute to this difference. Second, whether the U-shaped relationship between current alcohol intake…
How should we define health?
The WHO definition of health as complete wellbeing is no longer fit for purpose given the rise of chronic disease. Machteld Huber and colleagues propose changing the emphasis towards the ability to adapt and self manage in the face of social, physical, and emotional challenges
Towards a ‘patient-centred’ operationalisation of the new dynamic concept of health: A mixed methods study
OBJECTIVE: To evaluate among stakeholders the support for the new, dynamic concept of health, as published in 2011: 'Health as the ability to adapt and to self-manage', and to elaborate perceived indicators of health in order to make the concept measurable. DESIGN: A mixed methods study: a qualitative first step with interviews and focus groups, followed by a quantitative survey. PARTICIPANTS: Representatives of seven healthcare stakeholder domai…
Magnitude and determinants of multimorbidity and health care utilization among patients attending public versus private primary care: A cross-sectional study from Odisha, India
Our findings suggest that, multimorbidity is being more reported in public primary care facilities. The pattern and health care utilization in both types of settings are different. A comprehensive care approach must be designed for private care providers
Cannabis policy in The Netherlands: Rationale and design of an experiment with a controlled legal (‘closed’) cannabis supply chain
Since the Dutch tolerance policy, allowing the purchase of cannabis in 'coffeeshops', is associated with problems of public order and safety as well as health risks, there has been a long debate about legalisation of cannabis production and supply. It was therefore decided to conduct an experiment with a controlled legal ('closed') cannabis supply chain for recreational use. This is of international relevance in view of the current illegal cannab…
Medicine (14 works) · Environmental health (7 works) · Chronic Disease Management Strategies (6 works) · Population (6 works) · Psychiatry (6 works) · Family medicine (4 works) · Gerontology (4 works) · Internal Medicine (4 works) · Internal Medicine (4 works) · Psychology (4 works)