Richard Durbin
Biographic Data
| ID | 3456589 |
|---|---|
| NAME | Richard Durbin |
| GIVEN NAMES | Richard |
| FAMILY NAME | Durbin |
| SIGNATURE | DURBIN R |
| AFFILIATIONS | Wellcome Sanger Institute |
| ORCID | 0000-0002-9130-1006 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 312 |
| AUTHOR COUNT | 9 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2001 |
| LATEST PUBLICATION YEAR | 2019 |
| H-INDEX | 1 |
The population history of northeastern Siberia since the Pleistocene
A genomic history of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterized. Here we generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama–Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25–40 thousand years ago (kya), suggesting pre-Holocene population structure in the ancient continent of Sahul (Australia, New Guinea and Tasmania).…
Genomic evidence for the Pleistocene and recent population history of Native Americans
Genetic history of Native Americans Several theories have been put forth as to the origin and timing of when Native American ancestors entered the Americas. To clarify this controversy, Raghavan et al. examined the genomic variation among ancient and modern individuals from Asia and the Americas. There is no evidence for multiple waves of entry or recurrent gene flow with Asians in northern populations. The earliest migrations occurred no earlier…
A global reference for human genetic variation
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-genome sequencing, deep exome sequencing, and dense microarray genotyping. We characterized…
Biological Sequence Analysis
Apsa Congressional Fellows Office Assignments
Founded in 1953, the APSA Congressional Fellowship Program is the nation's oldest and most prestigious congressional fellowship. More than 50 years later, the program remains devoted to its original objective of expanding knowledge and awareness of Congress. For nine months, select political scientists, journalists, doctors, federal executives, and international scholars gain “hands on” understanding of the legislative process by serving on congr…
Fast and accurate short read alignment with Burrows–Wheeler transform
Motivation: The enormous amount of short reads generated by the new DNA sequencing technologies call for the development of fast and accurate read alignment programs. A first generation of hash table-based methods has been developed, including MAQ, which is accurate, feature rich and fast enough to align short reads from a single individual. However, MAQ does not support gapped alignment for single-end reads, which makes it unsuitable for alignme…
The Sequence Alignment/Map format and SAMtools
The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms. It is flexible in style, compact in size, efficient in random access and is the format in which alignments from the 1000 Genomes Project are released. SAMtools implements various utilities for post-processing alignments in the SAM …
Initial sequencing and analysis of the human genome
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.
Initial sequencing and analysis of the human genome
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.
Fast and accurate short read alignment with Burrows–Wheeler transform
Motivation: The enormous amount of short reads generated by the new DNA sequencing technologies call for the development of fast and accurate read alignment programs. A first generation of hash table-based methods has been developed, including MAQ, which is accurate, feature rich and fast enough to align short reads from a single individual. However, MAQ does not support gapped alignment for single-end reads, which makes it unsuitable for alignme…
The Sequence Alignment/Map format and SAMtools
The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms. It is flexible in style, compact in size, efficient in random access and is the format in which alignments from the 1000 Genomes Project are released. SAMtools implements various utilities for post-processing alignments in the SAM …
Biological Sequence Analysis
Apsa Congressional Fellows Office Assignments
Founded in 1953, the APSA Congressional Fellowship Program is the nation's oldest and most prestigious congressional fellowship. More than 50 years later, the program remains devoted to its original objective of expanding knowledge and awareness of Congress. For nine months, select political scientists, journalists, doctors, federal executives, and international scholars gain “hands on” understanding of the legislative process by serving on congr…
Genomic evidence for the Pleistocene and recent population history of Native Americans
Genetic history of Native Americans Several theories have been put forth as to the origin and timing of when Native American ancestors entered the Americas. To clarify this controversy, Raghavan et al. examined the genomic variation among ancient and modern individuals from Asia and the Americas. There is no evidence for multiple waves of entry or recurrent gene flow with Asians in northern populations. The earliest migrations occurred no earlier…
A global reference for human genetic variation
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-genome sequencing, deep exome sequencing, and dense microarray genotyping. We characterized…
A genomic history of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterized. Here we generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama–Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25–40 thousand years ago (kya), suggesting pre-Holocene population structure in the ancient continent of Sahul (Australia, New Guinea and Tasmania).…
The population history of northeastern Siberia since the Pleistocene
Biology (5 works) · Genetics (4 works) · Genomics and Phylogenetic Studies (4 works) · Archaeology (3 works) · Computational biology (3 works) · Computer Science (3 works) · Demography (3 works) · DNA sequencing (3 works) · Gene (3 works) · Genome (3 works)