Alexander V Kudryavtsev
Biographic Data
| ID | 3812756 |
|---|---|
| NAME | Alexander V Kudryavtsev |
| GIVEN NAMES | Alexander V |
| FAMILY NAME | Kudryavtsev |
| SIGNATURE | KUDRYAVTSEV A V |
| AFFILIATIONS | Northern State Medical University |
| ORCID | 0000-0001-8902-8947 |
| VERIFIED | Yes |
| TOTAL WORKS | 21 |
| TOTAL CITATIONS | 10 |
| AUTHOR COUNT | 21 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2016 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
Influence of anthropometric and body composition parameters on handgrip strength in middle-aged and older adults in the Russian Arctic
BACKGROUND: Age-related decline in muscle strength is associated with metabolic changes and has a significant impact on performance status and quality of life in older adults. Sarcopenia is caused by a combination of sociodemographic, behavioral, physiological, and climatic factors, underscoring the relevance of studying predictors of muscle strength decline in populations living in unfavorable natural and climatic conditions of Russia’s European…
Single nucleotide variants in interferon system genes in indigenous and non-indigenous residents of the Arkhangelsk region
Background: In addition to climatic and social factors, individual susceptibility to infectious diseases among residents of the North is influenced by nucleotide sequence variants in interferon system genes. The protein products of these genes are involved in the immune response. Aim: The study aimed to assess the prevalence of single nucleotide variants in interferon system genes (IFNAR1, IFNAR2, IFNGR1, IFNL4 (IL-28B)) in indigenous and non-ind…
Potential Applications of Directed Acyclic Graphs in the Design and Interpretation of Biomedical Research
This article presents an algorithm for constructing and applying directed acyclic graphs (DAGs) in the planning of epidemiological and biomedical studies. DAGs are graphical tools for modeling complex relationships between variables, which is particularly relevant in biomedical science, where accurate assessment of causal relationships requires accounting for potential confounding factors. The importance of DAGs is emphasized for conceptualizing …
Intraocular pressure in the adult population of Arkhangelsk and its associations with socio-demographic characteristics, lifestyle, and general health status
Background: Glaucoma is considered one of the leading causes of disability. Intraocular pressure is a key risk factor for the development of glaucoma, which underscores the importance of its assessment and control. The pneumotonometric method for measuring intraocular pressure is being widely used in glaucoma screening diagnostics.Aim: The work aimed to determine population-based reference values and age-related changes in intraocular pressure am…
Renin-angiotensin system gene polymorphism and aging
A personalized healthy aging program, aimed at preservation of functional capacities in old ages, should consider genetic (hereditary) factors that determine the structure and functions of body organs and systems, and their age-related changes. Individual genetic characteristics of a person can influence the aging process. For this reason, recent research focuses on identifying genetic mechanisms of aging and longevity associated with multifactor…
Polymorphism of genes involved in the regulation of blood pressure in elderly residents of the Arkhangelsk region
BACKGROUND: Living in the northern climate is associated with increased cardiovascular stress, which highlights the necessity for the study of candidate genes associated with the risk of cardiovascular diseases in both the native population and newcomers. Polymorphic loci of the renin-angiotensin system, NO-synthase, and endothelin-1 system genes have been identified as contributors to cardiovascular dysfunction and age-related blood pressure shi…
Alcohol and cause-specific mortality in Russia
Narcology patients face markedly higher mortality risks-threefold from all causes and cardiovascular diseases, ninefold from external causes, and sevenfold from other causes. Compared with the general population, conventional mortality risk factors were less predictive of deaths in narcology patients
Dental health in the adult population of Arkhangelsk
BACKGROUND: The Arkhangelsk region is characterized by a high prevalence and intensity of dental diseases among adults, but most of the studies were either hospital-based or used small samples with questionable representativeness.AIM: This article is a protocol of an original study, the purpose of which is to assess the dental status and its association with somatic health in a representative sample of the adult population of Arkhangelsk.MATERIAL…
Using artificial intelligence to predict and prevent non-cancer mortality in patients with cancer
Aim: To present the ARILIS study aimed at assessing the use of artificial intelligence to analyze chest computed tomography (CT) data to predict and prevent non-cancer mortality in patients with cancer.Material and methods: This cohort study will include patients with cancer diagnosed in the Arkhangelsk region (AR) within the 2019-2023 period. The COVID-19 patients with pneumonia, patients with general medical conditions, and the population of th…
Association between Alcohol Consumption and Body Composition in Russian Adults and Patients Treated for Alcohol-Related Disorders
There is conflicting evidence about the association between alcohol consumption and body composition (BC). We aimed to investigate this association in Russian adults. The study population included 2357 residents of Arkhangelsk aged 35-69 years, and 272 in-patients treated for alcohol problems (narcological patients) who participated in the Know Your Heart (KYH) cross-sectional study in 2015-2017. The participants were divided into five subgroups …
Association between atmospheric air temperature and blood pressure among adult population in different seasons
BACKGROUND: The prevalence of hypertension in the Arkhangelsk region is steadily increasing. Despite the progress in the diagnostics and the availability of treatment, a half of the population are unaware of their hypertension and its potential consequences, and consequently, do not adhere to the prescribed medications. This lack of awareness, coupled with the challenging climatic conditions of the northern regions, can significantly increase the…
Obesity Prevalence and Associated Socio-Demographic Characteristics and Health Behaviors in Russia and Norway
Associations between obesity and socio-demographic and behavioral characteristics vary between populations. Exploring such differences should throw light on factors related to obesity. We examined associations between general obesity (GO, defined by body mass index) and abdominal obesity (AO, defined by waist-to-hip ratio) and sex, age, socio-economic characteristics (education, financial situation, marital status), smoking and alcohol consumptio…
Socioeconomic inequalities in physiological risk biomarkers and the role of lifestyles among Russians aged 35-69 years
Notable differences in risk biomarkers inequalities were observed according to the SEP measure employed. Clear educational inequalities in raised physiological risk biomarkers levels, particularly in blood pressure and C-reactive protein were seen in Russia and are partly explained by lifestyle factors, particularly obesity among women. These findings provide evidence-based information on the need for tackling health inequalities in the Russian p…
Preventive counselling of the population on smoking cessation and weight loss according to data from the "Know your heart" study
AIM: To determine the coverage of smoking or/and overweight residents of Russian cities with preventive counseling (PC) on smoking cessation and weight loss and identify the associations of obtaining these types of PC with demographic, socioeconomic, and behavioral characteristics.MATERIAL AND METHODS: The study was conducted based on data from the Know Your Heart study (Arkhangelsk and Novosibirsk, 20152018, n=3234). The coverage of individual g…
Study profile
RATIONALE AND AIMS: The population of North Russia has a high prevalence of both cardiovascular and dental diseases. The Arkhangelsk region was included in the third phase of the multicenter study entitled Epidemiology of cardiovascular diseases in Russian regions. Third study (ESSE-RF3). The ESSE-RF3 study studied the prevalence of cardiovascular diseases, their biological and behavioral risk factors, and the associations with regional economic,…
Weather Conditions and Outdoor Fall Injuries in Northwestern Russia
This study aimed to investigate associations between the weather conditions and the frequency of medically-treated, non-fatal accidental outdoor fall injuries (AOFIs) in a provincial region of Northwestern Russia. Data on all non-fatal AOFIs that occurred from January 2015 through June 2018 ( N = 1125) were extracted from the population-based Shenkursk Injury Registry (SHIR). Associations between the weather conditions and AOFIs were investigated…
Why does Russia have such high cardiovascular mortality rates? Comparisons of blood-based biomarkers with Norway implicate non-ischaemic cardiac damage
Background Russia has one of the highest rates of mortality from cardiovascular disease (CVD). At age 35–69 years, they are eight times higher than in neighbouring Norway. Comparing profiles of blood-based CVD biomarkers between these two populations can help identify reasons for this substantial difference in risk. Methods We compared age-standardised mean levels of CVD biomarkers for men and women aged 40–69 years measured in two cross-sectiona…
Primary care use and cardiovascular disease risk in Russian 40–69 year olds
Background The Russian Federation has very high cardiovascular disease (CVD) mortality rates compared with countries of similar economic development. This cross-sectional study compares the characteristics of CVD-free participants with and without recent primary care contact to ascertain their CVD risk and health status. Methods A total of 2774 participants aged 40–69 years with no self-reported CVD history were selected from a population-based s…
Risk factors for perinatal mortality in Murmansk County, Russia
BACKGROUND: Factors contributing to perinatal mortality (PM) in Northwest Russia remain unclear. This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk County Birth Registry. OBJECTIVE: This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk County Birt…
The First Population-Based Injury Register in Russia
From 1 January 2015, the first Russian population-based injury register has been routinely used for registration of all traumas requiring medical assistance in the municipality of Shenkursk, Arkhangelsk region. It was built up on the injury registration model that was used in Harstad, Norway. The aims of the injury registry are to monitor injury rates and develop evidence-based preventive measures at the municipal level. The source of information…
Epidemiology of Injuries in Shymkent, Southern Kazakhstan
External causes are ranked as the third most common cause of death in Kazakhstan. At the same time, Kazakhstan has the highest mortality from traffic injuries in the world warranting development of preventive programs based on the main principles of evidence-based medicine. Given considerable heterogeneity between different regions of Kazakhstan, preventive programs should be based on the regional evidence. In this descriptive study we present a …
The First Population-Based Injury Register in Russia
From 1 January 2015, the first Russian population-based injury register has been routinely used for registration of all traumas requiring medical assistance in the municipality of Shenkursk, Arkhangelsk region. It was built up on the injury registration model that was used in Harstad, Norway. The aims of the injury registry are to monitor injury rates and develop evidence-based preventive measures at the municipal level. The source of information…
Epidemiology of Injuries in Shymkent, Southern Kazakhstan
External causes are ranked as the third most common cause of death in Kazakhstan. At the same time, Kazakhstan has the highest mortality from traffic injuries in the world warranting development of preventive programs based on the main principles of evidence-based medicine. Given considerable heterogeneity between different regions of Kazakhstan, preventive programs should be based on the regional evidence. In this descriptive study we present a …
Study profile
RATIONALE AND AIMS: The population of North Russia has a high prevalence of both cardiovascular and dental diseases. The Arkhangelsk region was included in the third phase of the multicenter study entitled Epidemiology of cardiovascular diseases in Russian regions. Third study (ESSE-RF3). The ESSE-RF3 study studied the prevalence of cardiovascular diseases, their biological and behavioral risk factors, and the associations with regional economic,…
Association between atmospheric air temperature and blood pressure among adult population in different seasons
BACKGROUND: The prevalence of hypertension in the Arkhangelsk region is steadily increasing. Despite the progress in the diagnostics and the availability of treatment, a half of the population are unaware of their hypertension and its potential consequences, and consequently, do not adhere to the prescribed medications. This lack of awareness, coupled with the challenging climatic conditions of the northern regions, can significantly increase the…
Why does Russia have such high cardiovascular mortality rates? Comparisons of blood-based biomarkers with Norway implicate non-ischaemic cardiac damage
Background Russia has one of the highest rates of mortality from cardiovascular disease (CVD). At age 35–69 years, they are eight times higher than in neighbouring Norway. Comparing profiles of blood-based CVD biomarkers between these two populations can help identify reasons for this substantial difference in risk. Methods We compared age-standardised mean levels of CVD biomarkers for men and women aged 40–69 years measured in two cross-sectiona…
Epidemiology of Injuries in Shymkent, Southern Kazakhstan
External causes are ranked as the third most common cause of death in Kazakhstan. At the same time, Kazakhstan has the highest mortality from traffic injuries in the world warranting development of preventive programs based on the main principles of evidence-based medicine. Given considerable heterogeneity between different regions of Kazakhstan, preventive programs should be based on the regional evidence. In this descriptive study we present a …
Risk factors for perinatal mortality in Murmansk County, Russia
BACKGROUND: Factors contributing to perinatal mortality (PM) in Northwest Russia remain unclear. This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk County Birth Registry. OBJECTIVE: This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk County Birt…
The First Population-Based Injury Register in Russia
From 1 January 2015, the first Russian population-based injury register has been routinely used for registration of all traumas requiring medical assistance in the municipality of Shenkursk, Arkhangelsk region. It was built up on the injury registration model that was used in Harstad, Norway. The aims of the injury registry are to monitor injury rates and develop evidence-based preventive measures at the municipal level. The source of information…
Weather Conditions and Outdoor Fall Injuries in Northwestern Russia
This study aimed to investigate associations between the weather conditions and the frequency of medically-treated, non-fatal accidental outdoor fall injuries (AOFIs) in a provincial region of Northwestern Russia. Data on all non-fatal AOFIs that occurred from January 2015 through June 2018 ( N = 1125) were extracted from the population-based Shenkursk Injury Registry (SHIR). Associations between the weather conditions and AOFIs were investigated…
Why does Russia have such high cardiovascular mortality rates? Comparisons of blood-based biomarkers with Norway implicate non-ischaemic cardiac damage
Background Russia has one of the highest rates of mortality from cardiovascular disease (CVD). At age 35–69 years, they are eight times higher than in neighbouring Norway. Comparing profiles of blood-based CVD biomarkers between these two populations can help identify reasons for this substantial difference in risk. Methods We compared age-standardised mean levels of CVD biomarkers for men and women aged 40–69 years measured in two cross-sectiona…
Primary care use and cardiovascular disease risk in Russian 40–69 year olds
Background The Russian Federation has very high cardiovascular disease (CVD) mortality rates compared with countries of similar economic development. This cross-sectional study compares the characteristics of CVD-free participants with and without recent primary care contact to ascertain their CVD risk and health status. Methods A total of 2774 participants aged 40–69 years with no self-reported CVD history were selected from a population-based s…
Obesity Prevalence and Associated Socio-Demographic Characteristics and Health Behaviors in Russia and Norway
Associations between obesity and socio-demographic and behavioral characteristics vary between populations. Exploring such differences should throw light on factors related to obesity. We examined associations between general obesity (GO, defined by body mass index) and abdominal obesity (AO, defined by waist-to-hip ratio) and sex, age, socio-economic characteristics (education, financial situation, marital status), smoking and alcohol consumptio…
Socioeconomic inequalities in physiological risk biomarkers and the role of lifestyles among Russians aged 35-69 years
Notable differences in risk biomarkers inequalities were observed according to the SEP measure employed. Clear educational inequalities in raised physiological risk biomarkers levels, particularly in blood pressure and C-reactive protein were seen in Russia and are partly explained by lifestyle factors, particularly obesity among women. These findings provide evidence-based information on the need for tackling health inequalities in the Russian p…
Preventive counselling of the population on smoking cessation and weight loss according to data from the "Know your heart" study
AIM: To determine the coverage of smoking or/and overweight residents of Russian cities with preventive counseling (PC) on smoking cessation and weight loss and identify the associations of obtaining these types of PC with demographic, socioeconomic, and behavioral characteristics.MATERIAL AND METHODS: The study was conducted based on data from the Know Your Heart study (Arkhangelsk and Novosibirsk, 20152018, n=3234). The coverage of individual g…
Study profile
RATIONALE AND AIMS: The population of North Russia has a high prevalence of both cardiovascular and dental diseases. The Arkhangelsk region was included in the third phase of the multicenter study entitled Epidemiology of cardiovascular diseases in Russian regions. Third study (ESSE-RF3). The ESSE-RF3 study studied the prevalence of cardiovascular diseases, their biological and behavioral risk factors, and the associations with regional economic,…
Association between Alcohol Consumption and Body Composition in Russian Adults and Patients Treated for Alcohol-Related Disorders
There is conflicting evidence about the association between alcohol consumption and body composition (BC). We aimed to investigate this association in Russian adults. The study population included 2357 residents of Arkhangelsk aged 35-69 years, and 272 in-patients treated for alcohol problems (narcological patients) who participated in the Know Your Heart (KYH) cross-sectional study in 2015-2017. The participants were divided into five subgroups …
Association between atmospheric air temperature and blood pressure among adult population in different seasons
BACKGROUND: The prevalence of hypertension in the Arkhangelsk region is steadily increasing. Despite the progress in the diagnostics and the availability of treatment, a half of the population are unaware of their hypertension and its potential consequences, and consequently, do not adhere to the prescribed medications. This lack of awareness, coupled with the challenging climatic conditions of the northern regions, can significantly increase the…
Renin-angiotensin system gene polymorphism and aging
A personalized healthy aging program, aimed at preservation of functional capacities in old ages, should consider genetic (hereditary) factors that determine the structure and functions of body organs and systems, and their age-related changes. Individual genetic characteristics of a person can influence the aging process. For this reason, recent research focuses on identifying genetic mechanisms of aging and longevity associated with multifactor…
Polymorphism of genes involved in the regulation of blood pressure in elderly residents of the Arkhangelsk region
BACKGROUND: Living in the northern climate is associated with increased cardiovascular stress, which highlights the necessity for the study of candidate genes associated with the risk of cardiovascular diseases in both the native population and newcomers. Polymorphic loci of the renin-angiotensin system, NO-synthase, and endothelin-1 system genes have been identified as contributors to cardiovascular dysfunction and age-related blood pressure shi…
Alcohol and cause-specific mortality in Russia
Narcology patients face markedly higher mortality risks-threefold from all causes and cardiovascular diseases, ninefold from external causes, and sevenfold from other causes. Compared with the general population, conventional mortality risk factors were less predictive of deaths in narcology patients
Dental health in the adult population of Arkhangelsk
BACKGROUND: The Arkhangelsk region is characterized by a high prevalence and intensity of dental diseases among adults, but most of the studies were either hospital-based or used small samples with questionable representativeness.AIM: This article is a protocol of an original study, the purpose of which is to assess the dental status and its association with somatic health in a representative sample of the adult population of Arkhangelsk.MATERIAL…
Using artificial intelligence to predict and prevent non-cancer mortality in patients with cancer
Aim: To present the ARILIS study aimed at assessing the use of artificial intelligence to analyze chest computed tomography (CT) data to predict and prevent non-cancer mortality in patients with cancer.Material and methods: This cohort study will include patients with cancer diagnosed in the Arkhangelsk region (AR) within the 2019-2023 period. The COVID-19 patients with pneumonia, patients with general medical conditions, and the population of th…
Influence of anthropometric and body composition parameters on handgrip strength in middle-aged and older adults in the Russian Arctic
BACKGROUND: Age-related decline in muscle strength is associated with metabolic changes and has a significant impact on performance status and quality of life in older adults. Sarcopenia is caused by a combination of sociodemographic, behavioral, physiological, and climatic factors, underscoring the relevance of studying predictors of muscle strength decline in populations living in unfavorable natural and climatic conditions of Russia’s European…
Single nucleotide variants in interferon system genes in indigenous and non-indigenous residents of the Arkhangelsk region
Background: In addition to climatic and social factors, individual susceptibility to infectious diseases among residents of the North is influenced by nucleotide sequence variants in interferon system genes. The protein products of these genes are involved in the immune response. Aim: The study aimed to assess the prevalence of single nucleotide variants in interferon system genes (IFNAR1, IFNAR2, IFNGR1, IFNL4 (IL-28B)) in indigenous and non-ind…
Potential Applications of Directed Acyclic Graphs in the Design and Interpretation of Biomedical Research
This article presents an algorithm for constructing and applying directed acyclic graphs (DAGs) in the planning of epidemiological and biomedical studies. DAGs are graphical tools for modeling complex relationships between variables, which is particularly relevant in biomedical science, where accurate assessment of causal relationships requires accounting for potential confounding factors. The importance of DAGs is emphasized for conceptualizing …
Intraocular pressure in the adult population of Arkhangelsk and its associations with socio-demographic characteristics, lifestyle, and general health status
Background: Glaucoma is considered one of the leading causes of disability. Intraocular pressure is a key risk factor for the development of glaucoma, which underscores the importance of its assessment and control. The pneumotonometric method for measuring intraocular pressure is being widely used in glaucoma screening diagnostics.Aim: The work aimed to determine population-based reference values and age-related changes in intraocular pressure am…
Medicine (18 works) · Environmental health (13 works) · Internal Medicine (10 works) · Population (9 works) · Demography (7 works) · Geography (6 works) · Pathology (6 works) · Biology (4 works) · Blood pressure (4 works) · Epidemiology (4 works)