Lijun Xu
Biographic Data
| ID | 3916937 |
|---|---|
| NAME | Lijun Xu |
| GIVEN NAMES | Lijun |
| FAMILY NAME | Xu |
| SIGNATURE | XU L |
| AFFILIATIONS | Tongji Hospital |
| ORCID | 0000-0002-2122-3364 |
| VERIFIED | Yes |
| TOTAL WORKS | 21 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 21 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2015 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
The Configuration Effect of Green Financial Instruments on Environmental Innovation: A Fuzzy‐Set Qualitative Comparative Analysis
Green financial instruments help achieve an effective interaction between financial activities and environmental protection, and encourage firms to engage in environmental innovation. This study uses a configuration perspective to investigate how the combined paths of various green financial instruments drive firms' environmental innovation. One hundred sixty‐one energy companies listed under China's A‐share system formed the research sample, and…
Sustainable Development Path of Poverty Alleviation for Migrants in Urban Centralized Resettlement Areas in China
As an essential regional planning policy, poverty alleviation relocation significantly impacts the regional economy, environment, and social well-being and is critical for sustainable development in China. Based on the development of large urban centralized resettlement areas in Guizhou Province, this study improved the traditional sustainable livelihood analysis framework and constructed a livelihood capital evaluation system including natural, …
Nominal construction of epistemological positions and power relations in journalistic stance taking: Variation across British and Chinese media discourse in English
Pursuing new ways of understanding the norm of objectivity and journalistic authority in the analysis of contemporary journalistic discourse has been a focal point of interest. Latest developments in the study of journalistic discourse have extended beyond the more traditional critical discourse analysis to methodologies that involve large corpora of texts and in-depth linguistic analysis to capture attitudinal expressions. We aim to study episte…
Mapping the invisible helpers: Mesosystemic pathways to goal escalation among first-generation college students in elite Chinese universities
This study investigates how first-generation college students (FGCSs) in two elite Double First-Class Chinese universities recalibrate their academic and career goals through mesosystemic interactions during the early transition years. Drawing on 15 semi-structured interviews and 11 goal-formation timelines, we use reflexive thematic analysis to trace critical incidents and relational supports. The findings indicate a recurrent but not inevitable…
Efficacy and mechanism of topical Chinese herbal formulation JieZe-1 on female lower genital tract co-infection with HSV-2 and Candida albicans via upregulating the cGAS/STING/IFN-I pathway
ETHNOPHARMACOLOGICAL RELEVANCE: JieZe-1 (JZ-1) originates from the classic Chinese gynecological formula Yi Huang Tang and demonstrates efficacy against lower female reproductive tract infections. However, its effects and mechanisms on herpes simplex virus type 2 (HSV-2) and Candida albicans (C. albicans) co-infection remain unclear. AIM OF THE STUDY: This study aimed to investigate the effects and underlying mechanisms of JZ-1 against a co-infec…
Effects of Crop Rotation With Oat on Soil Microbial Communities, Chemical Properties, and Oat Yield in Southwest China
Oats ( Avena sativa L ) had become an important crop in southwest China due to their high nutritional value and excellent adaptability to the challenging climate. Continuous oat cropping can lead to reduced oat yield and soil degradation; meanwhile, crop rotation has been proven to be an effective way to alleviate the obstacles of continuous cropping. However, the effects of different crop‐oat rotation patterns on oat yield, soil chemical propert…
Chinese herbal prescription JZ-1 enhances host resistance to herpes simplex virus type 2 through regulating the MRN-ATM-CHK2 DNA damage response
The host MRN-ATM-CHK2 DDR pathway serves as a defensive mechanism against HSV-2 infection by being activated to restrict viral replication. However, HSV-2 infection simultaneously promotes MRE11 degradation, undermining this protective response. JZ-1 exerts its antiviral effects by preventing HSV-2-induced MRE11 degradation, thereby enhancing DDR activation and restricting HSV-2 infection
Integrating network pharmacology and transcriptomics reveals that Bushen Huoxue recipe ameliorates ferroptosis and apoptosis in granulosa cells by regulating PI3K/Akt signaling pathway in premature ov…
BHR effectively ameliorated ovarian function in CTX-induced POI mice by suppressing ferroptosis and apoptosis in GCs. This effect is mechanistically mediated by the activation of the PI3K/Akt signaling pathway. Furthermore, the Hmox1/GPX4 axis may be associated with BHR-mediated inhibition of ferroptosis
Comprehensive analysis of vulnerability status and associated affect factors among prehospital emergency patients: A single-center descriptive cross-sectional study
Background: Prehospital emergency care is a critical but often understudied aspect of healthcare. Patient vulnerability in this setting can significantly impact outcomes. The aim of this study was to investigate the vulnerability status and to determine associated affect factors among prehospital emergency patients in China. Methods: In this cross-sectional study conducted in China, from April 2023 to July 2023, we assessed the vulnerability of p…
Green finance policy instrument mix and firms' environmental innovation: Does firm life‐cycle stage matter
Many countries around the world have introduced green finance policies to promote environmental innovation activities. Based on institutional theory and life‐cycle theory, this study constructs a model among green finance, life cycle, and firms' environmental innovation. The research sample consists of 558 Shanghai and Shenzhen A‐share manufacturing listed firms from 2010 to 2021. Using multiple regression analysis, this study examines the influe…
Comprehensive assessment of emergency departments in county-level public hospitals: A multicenter descriptive cross-sectional study in Henan province, China
Background Emergency Departments (EDs) play a crucial role in providing immediate medical care, particularly in densely populated countries like China. While previous research has predominantly focused on well-funded urban hospitals, this study offers a comprehensive evaluation of EDs in county-level public hospitals in Henan province, China, aiming to identify disparities and challenges. Methods A descriptive cross-sectional survey was conducted…
Assessment of disaster preparedness and related impact factors among emergency nurses in tertiary hospitals: Descriptive cross-sectional study from Henan Province of China
Background The aim of this study was to investigate the current state of disaster preparedness and to determine associated factors among emergency nurses from tertiary hospitals in Henan Province of China. Methods This multicenter descriptive cross-sectional study was conducted with emergency nurses from 48 tertiary hospitals in Henan Province of China between September 7, 2022–September 27, 2022. Data were collected through a self-designeds onli…
Wutou decoction attenuates the synovial inflammation of collagen-induced arthritis rats via regulating macrophage M1/M2 type polarization
NF-κB and PPARγ regulating M1 and M2 macrophage polarization and subsequent secretion of pro-inflammatory and anti-inflammatory cytokines are the underlying mechanisms of WTD that ameliorate RA synovial inflammation
Physical Activity, Individual Emotions, and Prosocial Attitudes: The Role Of Citizen Identity
Using data from 10,154 participants in the Chinese General Social Survey, we examined the effect of physical activity on emotions and prosocial attitudes, and the moderating effect of citizen identity on the positive effect of physical activity. The findings showed that physical activity was positively related to happiness and social trust perception, and negatively related to depression. This study further found that the effects of physical acti…
Improved A-Star Algorithm for Long-Distance Off-Road Path Planning Using Terrain Data Map
To overcome the limitation of poor processing times for long-distance off-road path planning, an improved A-Star algorithm based on terrain data is proposed in this study. The improved A-Star algorithm for long-distance off-road path planning tasks was developed to identify a feasible path between the start and destination based on a terrain data map generated using a digital elevation model. This study optimised the algorithm in two aspects: dat…
Excessive Ties in Entrepreneurship Can Hurt: How Excess Entrepreneurial Ties Bring Negative Effects to the Firm
Entrepreneurial ties are a critical resource for development and survival of entrepreneurial firms; however, the mechanism of how entrepreneurial ties affect entrepreneurial performance remains unclear. This study advances existing research on social ties and entrepreneurship through investigating how entrepreneurial ties exert a curvilinear impact on entrepreneurial performance via absorptive capacity, and the curvilinear effect of entrepreneuri…
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats
The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway
Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation
Jinlida granule inhibits palmitic acid induced-intracellular lipid accumulation and enhances autophagy in NIT-1 pancreatic β cells through AMPK activation
The results suggest that JLDG could reduce intracellular lipid accumulation and enhance the autophagy in NIT-1 pancreatic β cells cultured with PA. The mechanism is possibly mediated by AMPK activation
Excessive Ties in Entrepreneurship Can Hurt: How Excess Entrepreneurial Ties Bring Negative Effects to the Firm
Entrepreneurial ties are a critical resource for development and survival of entrepreneurial firms; however, the mechanism of how entrepreneurial ties affect entrepreneurial performance remains unclear. This study advances existing research on social ties and entrepreneurship through investigating how entrepreneurial ties exert a curvilinear impact on entrepreneurial performance via absorptive capacity, and the curvilinear effect of entrepreneuri…
Jinlida granule inhibits palmitic acid induced-intracellular lipid accumulation and enhances autophagy in NIT-1 pancreatic β cells through AMPK activation
The results suggest that JLDG could reduce intracellular lipid accumulation and enhance the autophagy in NIT-1 pancreatic β cells cultured with PA. The mechanism is possibly mediated by AMPK activation
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats
The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway
Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation
Improved A-Star Algorithm for Long-Distance Off-Road Path Planning Using Terrain Data Map
To overcome the limitation of poor processing times for long-distance off-road path planning, an improved A-Star algorithm based on terrain data is proposed in this study. The improved A-Star algorithm for long-distance off-road path planning tasks was developed to identify a feasible path between the start and destination based on a terrain data map generated using a digital elevation model. This study optimised the algorithm in two aspects: dat…
Excessive Ties in Entrepreneurship Can Hurt: How Excess Entrepreneurial Ties Bring Negative Effects to the Firm
Entrepreneurial ties are a critical resource for development and survival of entrepreneurial firms; however, the mechanism of how entrepreneurial ties affect entrepreneurial performance remains unclear. This study advances existing research on social ties and entrepreneurship through investigating how entrepreneurial ties exert a curvilinear impact on entrepreneurial performance via absorptive capacity, and the curvilinear effect of entrepreneuri…
Comprehensive assessment of emergency departments in county-level public hospitals: A multicenter descriptive cross-sectional study in Henan province, China
Background Emergency Departments (EDs) play a crucial role in providing immediate medical care, particularly in densely populated countries like China. While previous research has predominantly focused on well-funded urban hospitals, this study offers a comprehensive evaluation of EDs in county-level public hospitals in Henan province, China, aiming to identify disparities and challenges. Methods A descriptive cross-sectional survey was conducted…
Assessment of disaster preparedness and related impact factors among emergency nurses in tertiary hospitals: Descriptive cross-sectional study from Henan Province of China
Background The aim of this study was to investigate the current state of disaster preparedness and to determine associated factors among emergency nurses from tertiary hospitals in Henan Province of China. Methods This multicenter descriptive cross-sectional study was conducted with emergency nurses from 48 tertiary hospitals in Henan Province of China between September 7, 2022–September 27, 2022. Data were collected through a self-designeds onli…
Wutou decoction attenuates the synovial inflammation of collagen-induced arthritis rats via regulating macrophage M1/M2 type polarization
NF-κB and PPARγ regulating M1 and M2 macrophage polarization and subsequent secretion of pro-inflammatory and anti-inflammatory cytokines are the underlying mechanisms of WTD that ameliorate RA synovial inflammation
Physical Activity, Individual Emotions, and Prosocial Attitudes: The Role Of Citizen Identity
Using data from 10,154 participants in the Chinese General Social Survey, we examined the effect of physical activity on emotions and prosocial attitudes, and the moderating effect of citizen identity on the positive effect of physical activity. The findings showed that physical activity was positively related to happiness and social trust perception, and negatively related to depression. This study further found that the effects of physical acti…
Comprehensive analysis of vulnerability status and associated affect factors among prehospital emergency patients: A single-center descriptive cross-sectional study
Background: Prehospital emergency care is a critical but often understudied aspect of healthcare. Patient vulnerability in this setting can significantly impact outcomes. The aim of this study was to investigate the vulnerability status and to determine associated affect factors among prehospital emergency patients in China. Methods: In this cross-sectional study conducted in China, from April 2023 to July 2023, we assessed the vulnerability of p…
Green finance policy instrument mix and firms' environmental innovation: Does firm life‐cycle stage matter
Many countries around the world have introduced green finance policies to promote environmental innovation activities. Based on institutional theory and life‐cycle theory, this study constructs a model among green finance, life cycle, and firms' environmental innovation. The research sample consists of 558 Shanghai and Shenzhen A‐share manufacturing listed firms from 2010 to 2021. Using multiple regression analysis, this study examines the influe…
Integrating network pharmacology and transcriptomics reveals that Bushen Huoxue recipe ameliorates ferroptosis and apoptosis in granulosa cells by regulating PI3K/Akt signaling pathway in premature ov…
BHR effectively ameliorated ovarian function in CTX-induced POI mice by suppressing ferroptosis and apoptosis in GCs. This effect is mechanistically mediated by the activation of the PI3K/Akt signaling pathway. Furthermore, the Hmox1/GPX4 axis may be associated with BHR-mediated inhibition of ferroptosis
The Configuration Effect of Green Financial Instruments on Environmental Innovation: A Fuzzy‐Set Qualitative Comparative Analysis
Green financial instruments help achieve an effective interaction between financial activities and environmental protection, and encourage firms to engage in environmental innovation. This study uses a configuration perspective to investigate how the combined paths of various green financial instruments drive firms' environmental innovation. One hundred sixty‐one energy companies listed under China's A‐share system formed the research sample, and…
Sustainable Development Path of Poverty Alleviation for Migrants in Urban Centralized Resettlement Areas in China
As an essential regional planning policy, poverty alleviation relocation significantly impacts the regional economy, environment, and social well-being and is critical for sustainable development in China. Based on the development of large urban centralized resettlement areas in Guizhou Province, this study improved the traditional sustainable livelihood analysis framework and constructed a livelihood capital evaluation system including natural, …
Nominal construction of epistemological positions and power relations in journalistic stance taking: Variation across British and Chinese media discourse in English
Pursuing new ways of understanding the norm of objectivity and journalistic authority in the analysis of contemporary journalistic discourse has been a focal point of interest. Latest developments in the study of journalistic discourse have extended beyond the more traditional critical discourse analysis to methodologies that involve large corpora of texts and in-depth linguistic analysis to capture attitudinal expressions. We aim to study episte…
Mapping the invisible helpers: Mesosystemic pathways to goal escalation among first-generation college students in elite Chinese universities
This study investigates how first-generation college students (FGCSs) in two elite Double First-Class Chinese universities recalibrate their academic and career goals through mesosystemic interactions during the early transition years. Drawing on 15 semi-structured interviews and 11 goal-formation timelines, we use reflexive thematic analysis to trace critical incidents and relational supports. The findings indicate a recurrent but not inevitable…
Efficacy and mechanism of topical Chinese herbal formulation JieZe-1 on female lower genital tract co-infection with HSV-2 and Candida albicans via upregulating the cGAS/STING/IFN-I pathway
ETHNOPHARMACOLOGICAL RELEVANCE: JieZe-1 (JZ-1) originates from the classic Chinese gynecological formula Yi Huang Tang and demonstrates efficacy against lower female reproductive tract infections. However, its effects and mechanisms on herpes simplex virus type 2 (HSV-2) and Candida albicans (C. albicans) co-infection remain unclear. AIM OF THE STUDY: This study aimed to investigate the effects and underlying mechanisms of JZ-1 against a co-infec…
Effects of Crop Rotation With Oat on Soil Microbial Communities, Chemical Properties, and Oat Yield in Southwest China
Oats ( Avena sativa L ) had become an important crop in southwest China due to their high nutritional value and excellent adaptability to the challenging climate. Continuous oat cropping can lead to reduced oat yield and soil degradation; meanwhile, crop rotation has been proven to be an effective way to alleviate the obstacles of continuous cropping. However, the effects of different crop‐oat rotation patterns on oat yield, soil chemical propert…
Chinese herbal prescription JZ-1 enhances host resistance to herpes simplex virus type 2 through regulating the MRN-ATM-CHK2 DNA damage response
The host MRN-ATM-CHK2 DDR pathway serves as a defensive mechanism against HSV-2 infection by being activated to restrict viral replication. However, HSV-2 infection simultaneously promotes MRE11 degradation, undermining this protective response. JZ-1 exerts its antiviral effects by preventing HSV-2-induced MRE11 degradation, thereby enhancing DDR activation and restricting HSV-2 infection
Medicine (8 works) · Biology (6 works) · Herpes simplex virus (4 works) · Internal Medicine (4 works) · Apoptosis (3 works) · Cross-sectional study (3 works) · Geography (3 works) · Herpesvirus Infections and Treatments (3 works) · Immunology (3 works) · Inflammation (3 works)