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Wutou decoction attenuates the synovial inflammation of collagen-induced arthritis rats via regulating macrophage M1/M2 type polarization

Bibliographic Data

ID14728530
AuthorsWeiji Lin (0000-0001-5268-262X, Tongji Hospital), Pan Shen (0000-0003-3374-0382, Tongji Hospital), Ying Huang (0000-0003-3569-7576, Tongji Hospital), Liang Han (0009-0005-2090-5530, Tongji Hospital), Xin Ba (0000-0002-9273-839X, Tongji Hospital), Yao Huang (0000-0003-4291-3484, Tongji Hospital), Jiahui Yan (0000-0003-1593-460X, Tongji Hospital), Tingting Li (0009-0002-0758-3109, Tongji Hospital), Lijun Xu (0000-0002-2122-3364, Tongji Hospital), Kai Qin (0000-0001-5132-7052, Tongji Hospital), Zhe Chen (0000-0003-3194-2933, Tongji Hospital), Shenghao Tu (0000-0001-8530-270X, Tongji Hospital, corresponding author)
Year2023
Volume301
Pages115802
Publication date2023-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2022.115802
PMID36209953
OpenAlexW4302362275
LanguageEN
Citations received14
References cited42

NF-κB and PPARγ regulating M1 and M2 macrophage polarization and subsequent secretion of pro-inflammatory and anti-inflammatory cytokines are the underlying mechanisms of WTD that ameliorate RA synovial inflammation

Arthritis · Cytokine · Inflammation · Interleukin · Proinflammatory cytokine · Rheumatoid arthritis · Synovial membrane · Synovitis · Tumor necrosis factor alpha · Immune cells in cancer · Medicine · Pharmacological Effects of Natural Compounds · Rheumatoid Arthritis Research and Therapies · Immunology · Internal Medicine · Pharmacology

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  • Jiawei Wutou Decoction Attenuates Knee Osteoarthritis by Modulating Mitochondrial Oxidative Stress via the JAK2/STAT3 Pathway

    Open Access•AYIXIAMU Maitituoheti, JIANG Xianglong et al.•Journal of Ethnopharmacology•2026

  • Traditional Chinese medicine in regulating macrophage polarization in immune response of inflammatory diseases

    Open Access•Shiyu Chen, Jiuseng Zeng et al.•Journal of Ethnopharmacology•2024

  • Dendropanax proteus root and its major bio-phytochemicals alleviate rheumatoid arthritis by inhibiting TLR4/CLEC1B/PI3K/Akt/NF-κB pathways

    Open Access•Li Yang, Yang Li et al.•Journal of Ethnopharmacology•2026

  • Wutou decoction alleviates arthritis inflammation in CIA mice by regulating Treg cell stability and Treg/Th17 balance via the JAK2/STAT3 pathway

    Open Access•Liang Han, Jiahui Yan et al.•Journal of Ethnopharmacology•2024

  • Screening bioactive compounds from Fangji Huangqi decoction for treating rheumatoid arthritis via COX-2 magnetic ligand fishing combined with in vivo validation

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  • Water extracts of Tibetan medicine Wuweiganlu attenuates experimental arthritis via inducing macrophage polarization towards the M2 type

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  • Wutou Decoction promotes chondrogenic differentiation of urine derived stem cells and alleviates osteoarthritis by inhibiting ESR1/NDRG3-mediated β-catenin signaling

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  • Vitamin D enhances the effect of Soufeng sanjie formula in alleviating joint inflammation in CIA mice through VDR-NOTCH3/DLL4 signaling in macrophages

    Open Access•Xiuzhu Wang, Liping Tan et al.•Journal of Ethnopharmacology•2025

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  • Wutou decoction

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  • A comprehensive strategy to clarify the pharmacodynamic constituents and mechanism of Wu-tou decoction based on the constituents migrating to blood and their in vivo process under pathological state

    Open Access•Xiaoxu Cheng, Enyu Lu et al.•Journal of Ethnopharmacology•2021

  • The significant inhibition on CYP3A caused by radix Aconiti single herb is not observed in the Wutou decoction

    Open Access•Jinjun Wu, Zaixing Cheng et al.•Journal of Ethnopharmacology•2015

Unique citing works14
Citations per year4,67
Citation span2023 - 2026 (4)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 14

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