Alessandro Miani
Biographic Data
| ID | 4898835 |
|---|---|
| NAME | Alessandro Miani |
| GIVEN NAMES | Alessandro |
| FAMILY NAME | Miani |
| SIGNATURE | MIANI A |
| AFFILIATIONS | University of Milan |
| ORCID | 0000-0001-6610-3510 |
| VERIFIED | Yes |
| TOTAL WORKS | 24 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 24 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1993 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
In-situ digestion and micro-destructive sampling for dental proteomic sex determination analysis using polyvinylalcohol-based gel
Novel micro-invasive method for dental proteomics using PVA-based hydrogels. • Enables sex determination from enamel with minimal or no structural damage. • Compatible with degraded samples, preserving cultural and forensic value. • Combines ethical preservation with cutting-edge archaeological analysis. • Sets a new standard for micro-destructive sampling in proteomics research. Determining biological sex is pivotal for archaeological and forens…
Germa
The proliferation of online misinformation undermines societal cohesion and democratic principles. Effectively combating this issue relies on developing automatic classifiers, which require training data to achieve high classification accuracy. However, while English-language resources are abundant, other languages are often neglected, creating a critical gap in our ability to address misinformation globally. Furthermore, this lack of data in lan…
Loose and Tight
Conspiracy theories (CTs) are spectacular narratives, widely spread, that pose societal threats. We test whether CTs might be linguistically creative products, which would facilitate their transmission and thereby account for their widespread popularity. We analyzed nominal compounds (e.g., mind control , carbon dioxide ; N = 1,713,568) from a large corpus of conspiracist and mainstream texts matched by topic. In conspiracist texts, compounds sho…
Migrants’ human rights and health protection during the Covid-19 pandemic in the Mediterranean Sea
This study aims to assess the situation of Italian hotspots for migrant reception during the COVID-19 pandemic, and specifically analyzing the situation of two hotspots located in the Sicily Region (Pozzallo harbor and Lampedusa Island), to identify critical issues. At the same time, we hypothesize solutions to guarantee the respect of human rights and suggest an operational protocol to be applied in similar situations, considering that the migra…
A topic models analysis of the news coverage of the Omicron variant in the United Kingdom press
Changes in sensemaking in the press closely matched the changes in the official discourse relating to Omicron and reflects the trajectory of the infection and its local consequences
The Distribution of Dengue Virus Serotype in Quang Nam Province (Vietnam) during the Outbreak in 2018
Objectives : Quang Nam province in the Centre of Vietnam has faced an outbreak of dengue hemorrhagic fever (DHF) in 2018. Although DHF is a recurrent disease in this area, no epidemiological and microbiological reports on dengue virus serotypes have been conducted mainly due to lack of facilities for such a kind of advanced surveillance. The aim of this study was to detect different dengue virus serotypes in patients' blood samples. Design and Me…
Operative Protocol for Testing the Efficacy of Nasal Filters in Preventing Airborne Transmission of Sars-CoV-2
A procedure and apparatus for assessing SARS-CoV-2 VFE for endonasal filters is proposed. The apparatus can be implemented for more sophisticated studies on contaminated aerosols
Interaction of Pelargonium sidoides Compounds with Lactoferrin and Sars-CoV-2
(1) Background: Pelargonium sidoides extracts and lactoferrin are two important natural, anti-inflammatory, and antiviral agents, which can interfere with the early stages of SARS-CoV-2 infection. Molecular docking and molecular dynamics simulation approaches have been applied to check for the occurrence of interactions of the Pelargonium sidoides compounds with lactoferrin and with SARS-CoV-2 components. (2) Methods: Computational methods have b…
Trends of Phase I Clinical Trials in the Latest Ten Years across Five European Countries
The main data and characteristics of phase 1 clinical studies registered on the ClinicalTrials.gov database for France, Germany, Italy, Spain and the United Kingdom have been investigated and subsequently compared. The above-mentioned countries were selected based on similarities in terms of demographic and Gross Domestic Product (GDP) data available on official government websites. (3) Results: A total number of 6878 phase 1 clinical trials were…
Monoclonal Antibodies against Sars-CoV-2
Even several months after the start of a massive vaccination campaign against COVID-19, mortality and hospital admission are still high in many countries. Monoclonal antibodies against SARS-CoV-2 are the ideal complement to vaccination in infected subjects who are at high risk for progression to severe disease. Based on data of the Italian Ministry of Health, in the period April-August 2021, monoclonal antibodies were prescribed to 6322 patients.…
Evaluation of Residual Infectivity after Sars-CoV-2 Aerosol Transmission in a Controlled Laboratory Setting
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is mainly transmitted through respiratory droplets, aerosols, or direct contact with fomites from an infected subject. It has been reported that SARS-CoV-2 is stable and viable in aerosol up to 16 h in controlled laboratory conditions. However, the aerosolization conditions varied a lot between the studies. In this work, an experimental laboratory model of SARS-CoV-2 aerosolization…
Lactoferrin as Antiviral Treatment in Covid-19 Management
Lactoferrin (Lf), a multifunctional cationic glycoprotein synthesized by exocrine glands and neutrophils, possesses an in vitro antiviral activity against SARS-CoV-2. Thus, we conducted an in vivo preliminary study to investigate the antiviral effect of oral and intranasal liposomal bovine Lf (bLf) in asymptomatic and mild-to-moderate COVID-19 patients. From April 2020 to June 2020, a total of 92 mild-to-moderate (67/92) and asymptomatic (25/92) …
School as ideal setting to promote health and wellbeing among young people
Background: Nowadays, young people face several health challenges. As children and teenagers spend most of their time in the classroom, schools may have the opportunity to positively influence students’ quality of life, playing a crucial role in fostering their health. The aim of this review was to analyze evidence that demonstrated why school is the ideal setting for thepromotion of young generations’ wellbeing. Methods: We have reviewed the ava…
Water Quality Assessment
Background: At global level, the vulnerability of aquifers is deteriorating at an alarming rate due to environmental pollution and intensive human activities. In this context, Local Health Authority ASL Lecce has launched the M.I.N.O.Re. (Not Compulsory Water Monitoring Activities at Regional level) project, in order to assess the vulnerability of the aquifer in Salento area (Puglia Region) by performing several non-compulsory analyses on groundw…
Covid-19 Outbreak Progression in Italian Regions
Epidemiological figures of the SARS-CoV-2 epidemic in Italy are higher than those observed in China. Our objective was to model the SARS-CoV-2 outbreak progression in Italian regions vs. Lombardy to assess the epidemic's progression. Our setting was Italy, and especially Lombardy, which is experiencing a heavy burden of SARS-CoV-2 infections. The peak of new daily cases of the epidemic has been reached on the 29th, while was delayed in Central an…
Searching for Sars-COV-2 on Particulate Matter
A number of nations were forced to declare a total shutdown due to COVID-19 infection, as extreme measure to cope with dramatic impact of the pandemic, with remarkable consequences both in terms of negative health outcomes and economic loses. However, in many countries a "Phase-2" is approaching and many activities will re-open soon, although with some differences depending on the severity of the outbreak experienced and SARS-COV-2 estimated diff…
Quantification of the Aluminum Content Leached into Foods Baked Using Aluminum Foil
In this study, determinations of the aluminum content in meat and fish performed after having cooked these foods using commercially available aluminum foil have been performed. The release of this chemical element was evaluated by cooking beef, chicken, and fish wrapped with commercial aluminum foil using seasoning or without seasoning in order to evaluate the effect on Al leaching into the food. The characterization of the food samples was carri…
Forecasting Covid-19 Dynamics in Brazil
The contribution of this paper is twofold. First, a new data driven approach for predicting the Covid-19 pandemic dynamics is introduced. The second contribution consists in reporting and discussing the results that were obtained with this approach for the Brazilian states, with predictions starting as of 4 May 2020. As a preliminary study, we first used an Long Short Term Memory for Data Training-SAE (LSTM-SAE) network model. Although this first…
Efficiency of an Air Cleaner Device in Reducing Aerosol Particulate Matter (PM) in Indoor Environments
Indoor air quality (IAQ) in household environments is mandatory since people spend most of their time in indoor environments. In order to guarantee a healthy environment, air purification devices are often employed. In the present work, a commercial household vacuum cleaner has been tested in order to verify its efficiency in reducing the mass concentration and particle number of aerosol particulate matter (PM). The efficiency has been tested mea…
Chlorine Dioxide Degradation Issues on Metal and Plastic Water Pipes Tested in Parallel in a Semi-Closed System
Chlorine dioxide (ClO 2 ) has been widely used as a disinfectant in drinking water in the past but its effects on water pipes have not been investigated deeply, mainly due to the difficult experimental set-up required to simulate real-life water pipe conditions. In the present paper, four different kinds of water pipes, two based on plastics, namely random polypropylene (PPR) and polyethylene of raised temperature (PERT/aluminum multilayer), and …
Air Pollution and Estimated Health Costs Related to Road Transportations of Goods in Italy
Background : The Italian Society of Environmental Medicine has performed a preliminary assessment of the health impact attributable to road freight traffic in Italy. Methods : We estimated fine particulate matter (PM10, PM2.5) and nitrogen oxides (NOx) generated by road transportation of goods in Italy considering the number of trucks, the emission factors and the average annual distance covered in the year 2016. Simulations on data concerning Ye…
Sulforaphane Cannot Protect Human Fibroblasts From Repeated, Short and Sublethal Treatments with Hydrogen Peroxide
A delicate balance of reactive oxygen species (ROS) exists inside the cell: when the mechanisms that control the level of ROS fail, the cell is in an oxidative stress state, a condition that can accelerate aging processes. To contrast the pro-aging effect of ROS, the supplementation of antioxidants has been recently proposed. Sulforaphane (SFN) is an isothiocyanate isolated from Brassica plants that has been shown to modulate many critical factor…
Symbolizing Iconic Indexes
The most recognized feature of music is the capacity to arouse emotions in listeners: are such emo¬tions inherent to music (indexes) or are they evoked by resemblance to an analogous emotional expression (icons)? The claim is that music is a conventionalized imitation of an expression of an emotional state (i.e., a symbolized iconic index), but to reach this form three evolutionary steps in human thinking are required: individual, joint, and coll…
Human dental arch shape evaluated by Euclidean‐distance matrix analysis
Form differences between biological structures can be evaluated using several approaches. When landmark data are available, a recently proposed method (euclidean‐distance matrix analysis) seems to be able to differentiate between size and shape differences. This method also localizes those areas which differ most between the two structures. We have applied it to analyze the sexual dimorphism in dental arch form in a sample of 50 men and 45 women.…
No prominent works on this page.
Human dental arch shape evaluated by Euclidean‐distance matrix analysis
Form differences between biological structures can be evaluated using several approaches. When landmark data are available, a recently proposed method (euclidean‐distance matrix analysis) seems to be able to differentiate between size and shape differences. This method also localizes those areas which differ most between the two structures. We have applied it to analyze the sexual dimorphism in dental arch form in a sample of 50 men and 45 women.…
Symbolizing Iconic Indexes
The most recognized feature of music is the capacity to arouse emotions in listeners: are such emo¬tions inherent to music (indexes) or are they evoked by resemblance to an analogous emotional expression (icons)? The claim is that music is a conventionalized imitation of an expression of an emotional state (i.e., a symbolized iconic index), but to reach this form three evolutionary steps in human thinking are required: individual, joint, and coll…
Efficiency of an Air Cleaner Device in Reducing Aerosol Particulate Matter (PM) in Indoor Environments
Indoor air quality (IAQ) in household environments is mandatory since people spend most of their time in indoor environments. In order to guarantee a healthy environment, air purification devices are often employed. In the present work, a commercial household vacuum cleaner has been tested in order to verify its efficiency in reducing the mass concentration and particle number of aerosol particulate matter (PM). The efficiency has been tested mea…
Chlorine Dioxide Degradation Issues on Metal and Plastic Water Pipes Tested in Parallel in a Semi-Closed System
Chlorine dioxide (ClO 2 ) has been widely used as a disinfectant in drinking water in the past but its effects on water pipes have not been investigated deeply, mainly due to the difficult experimental set-up required to simulate real-life water pipe conditions. In the present paper, four different kinds of water pipes, two based on plastics, namely random polypropylene (PPR) and polyethylene of raised temperature (PERT/aluminum multilayer), and …
Air Pollution and Estimated Health Costs Related to Road Transportations of Goods in Italy
Background : The Italian Society of Environmental Medicine has performed a preliminary assessment of the health impact attributable to road freight traffic in Italy. Methods : We estimated fine particulate matter (PM10, PM2.5) and nitrogen oxides (NOx) generated by road transportation of goods in Italy considering the number of trucks, the emission factors and the average annual distance covered in the year 2016. Simulations on data concerning Ye…
Sulforaphane Cannot Protect Human Fibroblasts From Repeated, Short and Sublethal Treatments with Hydrogen Peroxide
A delicate balance of reactive oxygen species (ROS) exists inside the cell: when the mechanisms that control the level of ROS fail, the cell is in an oxidative stress state, a condition that can accelerate aging processes. To contrast the pro-aging effect of ROS, the supplementation of antioxidants has been recently proposed. Sulforaphane (SFN) is an isothiocyanate isolated from Brassica plants that has been shown to modulate many critical factor…
School as ideal setting to promote health and wellbeing among young people
Background: Nowadays, young people face several health challenges. As children and teenagers spend most of their time in the classroom, schools may have the opportunity to positively influence students’ quality of life, playing a crucial role in fostering their health. The aim of this review was to analyze evidence that demonstrated why school is the ideal setting for thepromotion of young generations’ wellbeing. Methods: We have reviewed the ava…
Water Quality Assessment
Background: At global level, the vulnerability of aquifers is deteriorating at an alarming rate due to environmental pollution and intensive human activities. In this context, Local Health Authority ASL Lecce has launched the M.I.N.O.Re. (Not Compulsory Water Monitoring Activities at Regional level) project, in order to assess the vulnerability of the aquifer in Salento area (Puglia Region) by performing several non-compulsory analyses on groundw…
Covid-19 Outbreak Progression in Italian Regions
Epidemiological figures of the SARS-CoV-2 epidemic in Italy are higher than those observed in China. Our objective was to model the SARS-CoV-2 outbreak progression in Italian regions vs. Lombardy to assess the epidemic's progression. Our setting was Italy, and especially Lombardy, which is experiencing a heavy burden of SARS-CoV-2 infections. The peak of new daily cases of the epidemic has been reached on the 29th, while was delayed in Central an…
Searching for Sars-COV-2 on Particulate Matter
A number of nations were forced to declare a total shutdown due to COVID-19 infection, as extreme measure to cope with dramatic impact of the pandemic, with remarkable consequences both in terms of negative health outcomes and economic loses. However, in many countries a "Phase-2" is approaching and many activities will re-open soon, although with some differences depending on the severity of the outbreak experienced and SARS-COV-2 estimated diff…
Quantification of the Aluminum Content Leached into Foods Baked Using Aluminum Foil
In this study, determinations of the aluminum content in meat and fish performed after having cooked these foods using commercially available aluminum foil have been performed. The release of this chemical element was evaluated by cooking beef, chicken, and fish wrapped with commercial aluminum foil using seasoning or without seasoning in order to evaluate the effect on Al leaching into the food. The characterization of the food samples was carri…
Forecasting Covid-19 Dynamics in Brazil
The contribution of this paper is twofold. First, a new data driven approach for predicting the Covid-19 pandemic dynamics is introduced. The second contribution consists in reporting and discussing the results that were obtained with this approach for the Brazilian states, with predictions starting as of 4 May 2020. As a preliminary study, we first used an Long Short Term Memory for Data Training-SAE (LSTM-SAE) network model. Although this first…
Monoclonal Antibodies against Sars-CoV-2
Even several months after the start of a massive vaccination campaign against COVID-19, mortality and hospital admission are still high in many countries. Monoclonal antibodies against SARS-CoV-2 are the ideal complement to vaccination in infected subjects who are at high risk for progression to severe disease. Based on data of the Italian Ministry of Health, in the period April-August 2021, monoclonal antibodies were prescribed to 6322 patients.…
Evaluation of Residual Infectivity after Sars-CoV-2 Aerosol Transmission in a Controlled Laboratory Setting
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is mainly transmitted through respiratory droplets, aerosols, or direct contact with fomites from an infected subject. It has been reported that SARS-CoV-2 is stable and viable in aerosol up to 16 h in controlled laboratory conditions. However, the aerosolization conditions varied a lot between the studies. In this work, an experimental laboratory model of SARS-CoV-2 aerosolization…
Lactoferrin as Antiviral Treatment in Covid-19 Management
Lactoferrin (Lf), a multifunctional cationic glycoprotein synthesized by exocrine glands and neutrophils, possesses an in vitro antiviral activity against SARS-CoV-2. Thus, we conducted an in vivo preliminary study to investigate the antiviral effect of oral and intranasal liposomal bovine Lf (bLf) in asymptomatic and mild-to-moderate COVID-19 patients. From April 2020 to June 2020, a total of 92 mild-to-moderate (67/92) and asymptomatic (25/92) …
The Distribution of Dengue Virus Serotype in Quang Nam Province (Vietnam) during the Outbreak in 2018
Objectives : Quang Nam province in the Centre of Vietnam has faced an outbreak of dengue hemorrhagic fever (DHF) in 2018. Although DHF is a recurrent disease in this area, no epidemiological and microbiological reports on dengue virus serotypes have been conducted mainly due to lack of facilities for such a kind of advanced surveillance. The aim of this study was to detect different dengue virus serotypes in patients' blood samples. Design and Me…
Operative Protocol for Testing the Efficacy of Nasal Filters in Preventing Airborne Transmission of Sars-CoV-2
A procedure and apparatus for assessing SARS-CoV-2 VFE for endonasal filters is proposed. The apparatus can be implemented for more sophisticated studies on contaminated aerosols
Interaction of Pelargonium sidoides Compounds with Lactoferrin and Sars-CoV-2
(1) Background: Pelargonium sidoides extracts and lactoferrin are two important natural, anti-inflammatory, and antiviral agents, which can interfere with the early stages of SARS-CoV-2 infection. Molecular docking and molecular dynamics simulation approaches have been applied to check for the occurrence of interactions of the Pelargonium sidoides compounds with lactoferrin and with SARS-CoV-2 components. (2) Methods: Computational methods have b…
Trends of Phase I Clinical Trials in the Latest Ten Years across Five European Countries
The main data and characteristics of phase 1 clinical studies registered on the ClinicalTrials.gov database for France, Germany, Italy, Spain and the United Kingdom have been investigated and subsequently compared. The above-mentioned countries were selected based on similarities in terms of demographic and Gross Domestic Product (GDP) data available on official government websites. (3) Results: A total number of 6878 phase 1 clinical trials were…
Migrants’ human rights and health protection during the Covid-19 pandemic in the Mediterranean Sea
This study aims to assess the situation of Italian hotspots for migrant reception during the COVID-19 pandemic, and specifically analyzing the situation of two hotspots located in the Sicily Region (Pozzallo harbor and Lampedusa Island), to identify critical issues. At the same time, we hypothesize solutions to guarantee the respect of human rights and suggest an operational protocol to be applied in similar situations, considering that the migra…
A topic models analysis of the news coverage of the Omicron variant in the United Kingdom press
Changes in sensemaking in the press closely matched the changes in the official discourse relating to Omicron and reflects the trajectory of the infection and its local consequences
Loose and Tight
Conspiracy theories (CTs) are spectacular narratives, widely spread, that pose societal threats. We test whether CTs might be linguistically creative products, which would facilitate their transmission and thereby account for their widespread popularity. We analyzed nominal compounds (e.g., mind control , carbon dioxide ; N = 1,713,568) from a large corpus of conspiracist and mainstream texts matched by topic. In conspiracist texts, compounds sho…
Germa
The proliferation of online misinformation undermines societal cohesion and democratic principles. Effectively combating this issue relies on developing automatic classifiers, which require training data to achieve high classification accuracy. However, while English-language resources are abundant, other languages are often neglected, creating a critical gap in our ability to address misinformation globally. Furthermore, this lack of data in lan…
In-situ digestion and micro-destructive sampling for dental proteomic sex determination analysis using polyvinylalcohol-based gel
Novel micro-invasive method for dental proteomics using PVA-based hydrogels. • Enables sex determination from enamel with minimal or no structural damage. • Compatible with degraded samples, preserving cultural and forensic value. • Combines ethical preservation with cutting-edge archaeological analysis. • Sets a new standard for micro-destructive sampling in proteomics research. Determining biological sex is pivotal for archaeological and forens…
Medicine (14 works) · Coronavirus disease 2019 (COVID-19 (8 works) · Virology (8 works) · Chemistry (7 works) · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 (7 works) · COVID-19 epidemiological studies (6 works) · Disease (6 works) · 2019-20 coronavirus outbreak (5 works) · Computer Science (5 works) · Environmental Science (5 works)