S S Papiha
Biographic Data
| ID | 5204655 |
|---|---|
| NAME | S S Papiha |
| GIVEN NAMES | S S |
| FAMILY NAME | Papiha |
| SIGNATURE | PAPIHA S S |
| AFFILIATIONS | Newcastle University |
| VERIFIED | No |
| TOTAL WORKS | 37 |
| TOTAL CITATIONS | 17 |
| AUTHOR COUNT | 37 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1972 |
| LATEST PUBLICATION YEAR | 2003 |
| H-INDEX | 2 |
The Genetic Heritage of the Earliest Settlers Persists Both in Indian Tribal and Caste Populations
Tracing European Founder Lineages in the Near Eastern mtDNA Pool
Study of three hypervariable DNA loci (D1S7; D7S22 and D12S11) in three European populations
To investigate the population genetic characteristics and genetic affinity, DNA profiles of three highly polymorphic VNTR (variable number of tandem repeats) loci (D1S7; D7S22 and D12S11) were studied in 405 individuals from three major European populations (English, Spanish and Basques). Like other studies on VNTRs, a large significant heterozygote deficiency was observed in all three populations. This decrease was ascribed to the limitation, co…
Anthropology of the apolipoprotein E (apo E) gene
The distribution of apolipoprotein E (apo E) polymorphism was examined in 11 population groups not previously studied for this system. There is a marked difference in phenotype and gene frequency between the populations of England and Spain. The south European populations of Basques and Spanish non-Basques showed greater similarity to the populations of South Asia. The study clearly indicates that the distribution of apo E alleles does match with…
Complement C3 polymorphism in sixteen populations of Colombia. Results of “Expedicion humana”
Blood samples of 1.022 individuals of both sexes, collected during the “Expedicion Humana” programme. Twelve Indian group, two Negroes, two urban and one mestizo populations of Colombia were C3 typed. The results showed the urban samples have C3*F genotype frequencies (17 and 20%) similar to the Spanish population. The Negroe system, with lower C3*F gene frequencies (3.5 and 7%) also resembled their parental populations in Africa. The Mestizo pop…
HLA antigens (A,B,C and D) among two groups of Guahiboan speaking Indians in Colombia. “Results of expedicion humana”
The serological HLA types (A,B,C and D loci) were studied in the Sikuani and Guayabero, two Guahiboan speaking Indian groups inhabiting the eastern lowlands of Colombia. Besides restricted polymorphism, the results show significant differences only in two antigens, A2 and B35, suggesting genetic similarity among these tribes which belong to the same linguistic family. Genetic distances were calculated for comparison with other Colombian groups so…
Genetic study in Greek Sarakatsans. I. Blood groups and enzyme polymorphisms
A random sample from the endogamic population of Greek Sarakatsans has been studied for eight blood groups, eleven enzymic genetic systems and haemoglobin variants. The allelic frequencies of the polymorphic loci have been compared with those of other samples from the Greek mainland and other European populations. The Sarakatsans tend to resemble their neighbours. The comparison with European populations indicates that the Sarakatsans have gene f…
Khmers of Cambodia
A sample of the Khmer population from Cambodia has been examined for 30 single‐gene characters (10 blood groups and 20 serum and red cell systems). A locus‐by‐locus comparison suggests that the Khmers differ significantly in several systems from the populations of Eastern India and China. There is remarkable heterogeneity among their geographical neighbors. To elucidate the genetic relationship of the Khmer, genetic data were collected from vario…
Genetic structure and microdifferentiation among four endogamous groups of Maharashtra, Western India
Phenotype and gene frequencies of 24 blood group, serum protein and red cell enzyme loci are examined in four endogamous groups (Brahmin, Maratha, Gujarati Hindu Patel and Parsee) of Maharashtra, Western India. Several genetic systems are investigated for the first time in this region. Genetic heterogeneity is suggested, although the overall variation shows general agreement with the populations already studied from Western India. In addition to …
Molecular Applications in Biological Anthropology
List of contributors Preface 1. Introduction: a brief history of the RFLP E. J. Devor 2. Nuclear DNA polymorphisms as tools in biological anthropology J. Rogers 3. Molecular genetics of atherosclerosis in human and non-human primates J. E. Hixson 4. Hypervariable minisatellites and VNTRs M. L. Weiss and T. Turner 5. Molecular genetics of globin genes and human population studies J. Flint, J. B. Clegg and A. J. Boyce 6. Mitochondrial DNA: its uses…
Study of transferrin (TF), group specific component (GC) and alpha-1-antitrypsin (PI) subtypes in the populations of Basque country (Spain)
Genetic polymorphisms of three serum proteins Transferrin (TF), Group Specific Component (GC), and Alpha-l-Antitrypsin were investigated by isoelectric focusing (IEF) in the Basque and non Basque populations from Vizcaya and Guipuzcoa, Spain. Two of the three genetic systems (TF and PI) showed conclusive genetic heterogeneity between the Basque populations of these two provinces. In addition to the past genetic drift, the present day genetic diff…
Population genetics of the peoples of Iran I. Genetic polymorphisms of blood groups, serum proteins and red cell enzymes
Genetic polymorphisms of six blood groups and seven biochemical genetic markers were investigated in six Iranian populations (Turks, Kurds, Lurs, Zabolis, Baluchis and Zoroastrians). Eight of the genetic systems (ABO, MNSs, Kidd, C3, AP, AK, PGM1 and EsD) showed conclusive heterogeneity among these populations. Comparison of gene frequencies with the few available samples of Iranian populations demonstrated an intra-ethnic and extensive overall g…
Genetic variation in Brac, Croatia
A serological survey of the Dalmatian island of Brac (Croatia), based on a total sample of 747 subjects, shows considerable local genetic variation. While the overall gene frequencies are much as expected from the island's geographical position, the local genetic heterogeneity is made up of differences between the inland and coastal villages, differences between the two coastal areas, and variation among the older inland villages. This heterogene…
Population genetics of the people of Iran II. Genetic differentiation and population structure
The genetic structure of six populations of Iran (Turks, Kurds, Lurs, Zabolis, Baluchis and Zoroastrians) was examined using data on blood groups, serum proteins and cell enzymes. Our results show conclusively that there are genetic differences among the six populations and the analysis of superimposed R and S matrices defined Harpending & Jenkins (1973) show by that the dispersion of some of the alleles correspond to the dispersion of the popula…
Population variation in molecular polymorphisms of the short arm of the human X chromosome
Five DNA probes (RC8, 754, XJ 1‐1, pert 87.8, and L1.28) from the short arm of the human X chromosome were investigated in samples from five populations (English, Nigerian, Chinese, Muslim, and Hindu from India). The variation in the allele frequencies of several probes between different groups was significant. The average heterozygosity in females of the five populations ranged from 32% to 51%. The genetic distance between the five groups was co…
Serogenetic studies of the Lobanas in North-West India
Phenotype and gene frequencies of several polymorphic genetic markers were examined in a Sikh agriculturist caste group, Lobanas of Punjab, India. Lobanas have been a trading community, now settled as cultivators, but for their origin there have been a difference of opinions. To trace their genetic relationship the gene frequency data was compared using multivariate analysis with several populations of India, which historically shared not only a …
Genetic variation in north-east England
Phenotype and gene frequencies of polymorphic systems in blood specimens from 796 donors in Northumberland and Durham (north-east England) were analysed according to region of residence. Significant differences exist among the five geographically defined subpopulations, and it is argued that these derive from patterns of historical settlement
Gene frequencies of Gc and PGM subtypes
Allele frequencies are presented for subtypes of phosphoglucomutase locus 1 and the group-specific component (Gc) in samples from a number of human populations. Compared with each other and with published data, continental samples are very similar in gene frequency to their reported distributions in the literature, but the small island populations are much more variable
Population and biochemical genetics of the human mitochondrial malic enzyme
The phenotypic variation of the mitochondrial malic enzyme (MEM) was examined in 121 brains and 46 heart tissue samples from the population of north-east England. There was no difference in gene frequency distribution between sexes and the two tissues. However, a significant variation has been observed in males compared with a Scottish study. The three common phenotypes of brain were partially purified on a DEAE Sephadex column. The kinetics, hea…
Genetic and environmental factors affecting immunoglobulin levels in Iran
Studies in the last two decades have demonstrated the great variation in the levels of gammaglobulins that occur in different populations. These provide a useful if preliminary measure of the ecological stress that the population is under, from the assault of infections and similar agents. Many biological as well as environmental factors contribute to normal variation in the concentration of these plasma proteins, however, (Kalff, 1970), and thes…
Serogenetic studies among an urban and two tribal populations of Orissa, India
Phenotype and gene frequencies of blood groups, plasma proteins and red cell enzymes (23 systems) are examined in two tribal and one low social class urban population of Orissa, India. Genetic heterogeneity is suggested not only between the tribal and urban populations but also between the tribal groups. The gene frequencies of tribal populations indicate a genepool with an ancestral component from the populations of north-east India with some mo…
Genetic variation and disease susceptibility in NCWP groups in Britain
Genetic studies in New Commonwealth and Pakistani (NCWP) groups resident in Britain show not only that these populations differ from one another but also that there are considerable genetic differences among the groups migrating from a single region of the Indian sub‐continent. Investigations show that for various disorders, such as diabetes, cirrhosis of the liver, cerebrovascular and heart disorders, the NCWP communities have higher morbidity a…
Population genetics of the Persians and other peoples in Iran
Group-specific component (Gc) subtypes in Gambian and Transkeian populations
A total of 270 serum specimens from Keneba and Manduar villages of The Gambia and 126 from Bantu of Transkei were examined for the group-specific component (Gc) phenotypes by isoelectric focusing. Only one individual showed phenotype 2-2 in the Bantu population, and the sub-allele frequencies showed a distribution very characteristic of African populations. A new rare mutation, Gc1C34, was found in heterozygous combination with Gc2 allele. The sy…
HLA antigen frequency in the Koya tribe of Andhra Pradesh, India
The frequencies of HLA‐A, ‐B, and ‐C antigens were studied in a tribal population of Koya from Andhra Pradesh in southern India. No other well‐defined tribal population has been studied with which the present results may be compared. However, the HLA profile of Koya showed distinct differences from the general HLA distribution in India in the frequency of a large number of antigens both at the A and B loci. This study indicates the distinctivenes…
Population genetics of the group specific component (Gc) and phosphoglucomutase (PGM 1 ) studied by isoelectric focusing
For the determination of the group‐specific component (Gc) and phosphoglucomutase (PGM 1 ) phenotypes, isoelectric focusing was performed on two samples, one of Jat Sikh of northwest India, the other of northeast English. The subtype frequencies of these two systems do not differentiate the two populations sampled. Synthesis of the existing data shows distinct PGM 1 and Gc subtype frequencies in various ethnic and racial groups. The anthropologic…
A genetic survey in the Bhil tribe of Madhya Pradesh, Central India
Examination of blood groups, plasma proteins and red cell enzyme types (23 loci), in a sample of 145 Bhils, a tribal group of Madhya Pradesh, Central India, demonstrates their genetic uniqueness. They differ in a number of systems from the nearby nontribal groups both of Hindus and Muslims. The results suggest that the Bhil frequencies include vestiges of the ancestral genepool of a more widespread aboriginal population whose influence is detecta…
Serogenetic studies of the Lobanas in North-West India
Phenotype and gene frequencies of several polymorphic genetic markers were examined in a Sikh agriculturist caste group, Lobanas of Punjab, India. Lobanas have been a trading community, now settled as cultivators, but for their origin there have been a difference of opinions. To trace their genetic relationship the gene frequency data was compared using multivariate analysis with several populations of India, which historically shared not only a …
Genetic studies among Kanet and Koli of Kinnar district in Himachal Pradesh, India
Data are presented on serological and electrophoretic variants of 18 systems of red cells in 228 individuals belonging to a scheduled tribe (Kanet) and a scheduled caste (Koli) of Kinnar district in Himachal Pradesh, India. Differences in gene frequencies clearly indicate biological distinction in the local population. The possible cause of this genetic heterogeneity is discussed
Complement Variation and Anthropology
Molecular Anthropology
Molecular Applications in Biological Anthropology
List of contributors Preface 1. Introduction: a brief history of the RFLP E. J. Devor 2. Nuclear DNA polymorphisms as tools in biological anthropology J. Rogers 3. Molecular genetics of atherosclerosis in human and non-human primates J. E. Hixson 4. Hypervariable minisatellites and VNTRs M. L. Weiss and T. Turner 5. Molecular genetics of globin genes and human population studies J. Flint, J. B. Clegg and A. J. Boyce 6. Mitochondrial DNA: its uses…
HLA antigen frequency in the Koya tribe of Andhra Pradesh, India
The frequencies of HLA‐A, ‐B, and ‐C antigens were studied in a tribal population of Koya from Andhra Pradesh in southern India. No other well‐defined tribal population has been studied with which the present results may be compared. However, the HLA profile of Koya showed distinct differences from the general HLA distribution in India in the frequency of a large number of antigens both at the A and B loci. This study indicates the distinctivenes…
Red cell enzyme polymorphisms in Punjabis in north India
Seven red cell isoenzyme systems were investigated on a sample of 140 Punjabis from Hoshiarpur and Chandigarh, shown to be representative by comparison of their blood group frequencies with other samples from the area. Phenotype and gene frequencies are given for adenosine deaminase, adenylate kinase, acid phosphatase, 6‐phosphogluconate dehydrogenase, phosphoglucomutase locus 1 and 2, lactate dehydrogenase and phosphohexose isomerase. The high f…
Haptoglobin distribution in north-east England
In north-east England local differences in the frequency of haptoglobin types support the biological distinction of the population of south-east Northumberland from the remainder of the county
A survey of glucose‐6‐phosphate‐dehydrogenase deficiency in the North Central Province of Sri Lanka (formerly Ceylon)
A high frequency of the G6PD deficient gene was detected in the North Central Province of Sri Lanka. The frequency in the ancient villages is much higher than that of the recently colonized areas. The Sinhalese and Ceylon Moors have a significantly higher frequency as opposed to the Ceylon Tamils. The distribution appears to be related to a history of exposure to malarial endemicity
A genetic survey in the Bhil tribe of Madhya Pradesh, Central India
Examination of blood groups, plasma proteins and red cell enzyme types (23 loci), in a sample of 145 Bhils, a tribal group of Madhya Pradesh, Central India, demonstrates their genetic uniqueness. They differ in a number of systems from the nearby nontribal groups both of Hindus and Muslims. The results suggest that the Bhil frequencies include vestiges of the ancestral genepool of a more widespread aboriginal population whose influence is detecta…
Molecular Anthropology
Complement Variation and Anthropology
A genetic study of some Andhra Pradesh populations
Phenotype and gene frequencies of 10 blood group and 12 red cell enzymes are examined in urban Hindu and Muslim and tribal Lambadi samples of Andhra Pradesh, South India. Genetic heterogeneity is suggested between the tribal and the urban samples, both in their gene frequencies and in their breeding structure
Genetic studies among Kanet and Koli of Kinnar district in Himachal Pradesh, India
Data are presented on serological and electrophoretic variants of 18 systems of red cells in 228 individuals belonging to a scheduled tribe (Kanet) and a scheduled caste (Koli) of Kinnar district in Himachal Pradesh, India. Differences in gene frequencies clearly indicate biological distinction in the local population. The possible cause of this genetic heterogeneity is discussed
Serological and biochemical variation in the Gaddi tribe of Himachal Pradesh, India
Phosphoglucomutase (PGM) and group-specific component (Gc), isoelectric focusing sub-types among Zoroastrians of Iran
A total of 243 and 236 red cell and serum samples from the Zoroastrians of Iran were sub-typed by isoelectric focusing for the red cell enzyme phosphoglucomutase locus 1 and the group-specific component respectively and the phenotype and gene frequency values were calculated. Comparison of the results with those of examinations performed on African, Asian and European population shows that for both the PGM and Gc systems Zoroastrians show similar…
Genetic heterogeneity and population structure in north-west India
Genetic markers consisting of 11 blood group and red cell enzyme systems were investigated in 14 endogamous groups of north-west India. Genetic differentiation among the samples as indicated by FST is appreciable, reflecting the ethnic diversity characteristic of this region. Local variation within each state is lower, indicating a geographical component to the total variation. This variation is refined by calculations of genetic distances, which…
Population genetics of the group specific component (Gc) and phosphoglucomutase (PGM 1 ) studied by isoelectric focusing
For the determination of the group‐specific component (Gc) and phosphoglucomutase (PGM 1 ) phenotypes, isoelectric focusing was performed on two samples, one of Jat Sikh of northwest India, the other of northeast English. The subtype frequencies of these two systems do not differentiate the two populations sampled. Synthesis of the existing data shows distinct PGM 1 and Gc subtype frequencies in various ethnic and racial groups. The anthropologic…
HLA antigen frequency in the Koya tribe of Andhra Pradesh, India
The frequencies of HLA‐A, ‐B, and ‐C antigens were studied in a tribal population of Koya from Andhra Pradesh in southern India. No other well‐defined tribal population has been studied with which the present results may be compared. However, the HLA profile of Koya showed distinct differences from the general HLA distribution in India in the frequency of a large number of antigens both at the A and B loci. This study indicates the distinctivenes…
Group-specific component (Gc) subtypes in Gambian and Transkeian populations
A total of 270 serum specimens from Keneba and Manduar villages of The Gambia and 126 from Bantu of Transkei were examined for the group-specific component (Gc) phenotypes by isoelectric focusing. Only one individual showed phenotype 2-2 in the Bantu population, and the sub-allele frequencies showed a distribution very characteristic of African populations. A new rare mutation, Gc1C34, was found in heterozygous combination with Gc2 allele. The sy…
Population genetics of the Persians and other peoples in Iran
Genetic variation and disease susceptibility in NCWP groups in Britain
Genetic studies in New Commonwealth and Pakistani (NCWP) groups resident in Britain show not only that these populations differ from one another but also that there are considerable genetic differences among the groups migrating from a single region of the Indian sub‐continent. Investigations show that for various disorders, such as diabetes, cirrhosis of the liver, cerebrovascular and heart disorders, the NCWP communities have higher morbidity a…
Genetic and environmental factors affecting immunoglobulin levels in Iran
Studies in the last two decades have demonstrated the great variation in the levels of gammaglobulins that occur in different populations. These provide a useful if preliminary measure of the ecological stress that the population is under, from the assault of infections and similar agents. Many biological as well as environmental factors contribute to normal variation in the concentration of these plasma proteins, however, (Kalff, 1970), and thes…
Serogenetic studies among an urban and two tribal populations of Orissa, India
Phenotype and gene frequencies of blood groups, plasma proteins and red cell enzymes (23 systems) are examined in two tribal and one low social class urban population of Orissa, India. Genetic heterogeneity is suggested not only between the tribal and urban populations but also between the tribal groups. The gene frequencies of tribal populations indicate a genepool with an ancestral component from the populations of north-east India with some mo…
Gene frequencies of Gc and PGM subtypes
Allele frequencies are presented for subtypes of phosphoglucomutase locus 1 and the group-specific component (Gc) in samples from a number of human populations. Compared with each other and with published data, continental samples are very similar in gene frequency to their reported distributions in the literature, but the small island populations are much more variable
Population and biochemical genetics of the human mitochondrial malic enzyme
The phenotypic variation of the mitochondrial malic enzyme (MEM) was examined in 121 brains and 46 heart tissue samples from the population of north-east England. There was no difference in gene frequency distribution between sexes and the two tissues. However, a significant variation has been observed in males compared with a Scottish study. The three common phenotypes of brain were partially purified on a DEAE Sephadex column. The kinetics, hea…
Genetic variation in north-east England
Phenotype and gene frequencies of polymorphic systems in blood specimens from 796 donors in Northumberland and Durham (north-east England) were analysed according to region of residence. Significant differences exist among the five geographically defined subpopulations, and it is argued that these derive from patterns of historical settlement
Population variation in molecular polymorphisms of the short arm of the human X chromosome
Five DNA probes (RC8, 754, XJ 1‐1, pert 87.8, and L1.28) from the short arm of the human X chromosome were investigated in samples from five populations (English, Nigerian, Chinese, Muslim, and Hindu from India). The variation in the allele frequencies of several probes between different groups was significant. The average heterozygosity in females of the five populations ranged from 32% to 51%. The genetic distance between the five groups was co…
Serogenetic studies of the Lobanas in North-West India
Phenotype and gene frequencies of several polymorphic genetic markers were examined in a Sikh agriculturist caste group, Lobanas of Punjab, India. Lobanas have been a trading community, now settled as cultivators, but for their origin there have been a difference of opinions. To trace their genetic relationship the gene frequency data was compared using multivariate analysis with several populations of India, which historically shared not only a …
Population genetics of the peoples of Iran I. Genetic polymorphisms of blood groups, serum proteins and red cell enzymes
Genetic polymorphisms of six blood groups and seven biochemical genetic markers were investigated in six Iranian populations (Turks, Kurds, Lurs, Zabolis, Baluchis and Zoroastrians). Eight of the genetic systems (ABO, MNSs, Kidd, C3, AP, AK, PGM1 and EsD) showed conclusive heterogeneity among these populations. Comparison of gene frequencies with the few available samples of Iranian populations demonstrated an intra-ethnic and extensive overall g…
Genetic variation in Brac, Croatia
A serological survey of the Dalmatian island of Brac (Croatia), based on a total sample of 747 subjects, shows considerable local genetic variation. While the overall gene frequencies are much as expected from the island's geographical position, the local genetic heterogeneity is made up of differences between the inland and coastal villages, differences between the two coastal areas, and variation among the older inland villages. This heterogene…
Biology (33 works) · Demography (21 works) · Genetics (20 works) · Population (20 works) · Sociology (20 works) · Gene (19 works) · Geography (19 works) · Evolutionary biology (14 works) · Allele (11 works) · Demography (11 works)