Group-specific component (Gc) subtypes in Gambian and Transkeian populations

A description of a new variant

Bibliographic Data

ID13924344
AuthorsS S Papiha (Newcastle University, corresponding author), J Constans (0000-0002-0634-6024, Centre National de la Recherche Scientifique), I White (0000-0001-7593-6338, Liverpool School of Tropical Medicine), I McGregor (Newcastle University), I A McGregor
Year1985
Volume12
Issue1
Pages17-26
Publication date1985-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnnals of Human Biology (JOURNAL)
Journal identifiersISSN: 0301-4460 • E-ISSN: 1464-5033
PublisherInforma (PUBLISHER • GB)
DOI10.1080/03014468500007531
PMID3977281
OpenAlexW2136240919
LanguageEN
Citations received3
References cited31

A total of 270 serum specimens from Keneba and Manduar villages of The Gambia and 126 from Bantu of Transkei were examined for the group-specific component (Gc) phenotypes by isoelectric focusing. Only one individual showed phenotype 2-2 in the Bantu population, and the sub-allele frequencies showed a distribution very characteristic of African populations. A new rare mutation, Gc1C34, was found in heterozygous combination with Gc2 allele. The synthesis of the existing Gc sub-type data was examined for its anthropological implications

Allele · Allele frequency · Bantu languages · Biology · Evolutionary biology · Gene · Isoelectric focusing · Phenotype · Population · Sociology · Demography · Genomic variations and chromosomal abnormalities · Genomics and Rare Diseases · Immunodeficiency and Autoimmune Disorders · Genetics

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