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Gc (vitamin D binding protein) subtype polymorphism and variants distribution among Saharan, Middle East, and African populations

Bibliographic Data

ID20537733
AuthorsJ Constans (0000-0002-0634-6024), Ph Lefevre‐Witier, Ph Lefèvre-Witier, P Richard (0000-0003-3943-5178), Geert De Jaeger (0000-0001-6558-5669, Hôpital Cochin)
Year1980
Volume52
Issue3
Pages435-441
Publication date1980-03-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.1330520315
PMID6155786
OpenAlexW2028857073
LanguageEN
Citations received11
References cited13

This article presents the results obtained by electrophoretic analysis of the group specific component polymorphism in more than 1,250 serum samples from populations living in the Sahara, the Middle East, and equatorial Africa. In addition to the alleles Gc IF and Gc IS , five variants, including one previously unknown, were found. The distribution of the alleles herein described permits speculation on exchanges and relation among the groups considered. The lowest frequencies of the gene Gc 2 correspond to regions where sunlight is stronger. There is also a north‐south gradient in the Gc IF gene frequency. This seems to parallel the gradient seen in skin pigmentation

Allele · Allele frequency · Biology · Distribution (mathematics) · Gene · Polymorphism (computer science) · Acne and Rosacea Treatments and Effects · Erythrocyte Function and Pathophysiology · Genetics · Vitamin D Research Studies

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Unique citing works11
Citations per year0,24
Citation span1981 - 2012 (32)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 10

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