Naveed Sattar
Biographic Data
| ID | 5482630 |
|---|---|
| NAME | Naveed Sattar |
| GIVEN NAMES | Naveed |
| FAMILY NAME | Sattar |
| SIGNATURE | SATTAR N |
| AFFILIATIONS | University of Glasgow |
| ORCID | 0000-0002-1604-2593 |
| VERIFIED | Yes |
| TOTAL WORKS | 26 |
| TOTAL CITATIONS | 6 |
| AUTHOR COUNT | 26 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2008 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 1 |
Cross-sectional study of the associations between circulating vitamin D concentrations and insulin resistance in children aged 9–10 years of South Asian, black African Caribbean and white European ori…
BACKGROUND: Lower circulating vitamin D 25-hydroxyvitamin D (25(OH)D) concentrations are associated with higher type 2 diabetes risk in adults, although causality remains uncertain. However, associations between 25(OH)D and type 2 diabetes risk markers in children have been little studied, particularly in ethnic minority populations. We examined whether 25(OH)D concentrations were associated with insulin resistance in children and whether lower 2…
Identifying the Biomarker Profile of Pre-Frail and Frail People
Several biomarkers were linked to pre-frailty and frailty. Nonetheless, some of the associations differed by sex. Our findings contribute to a broader understanding of the pathophysiology of frailty as currently defined
ESC Guidelines on cardiovascular disease prevention in clinical practice
The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of their publication. The ESC is not responsible in the event of any contradiction, discrepancy and/or ambiguity between the ESC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to goo…
Occupation and risk of severe Covid-19
OBJECTIVES: To investigate severe COVID-19 risk by occupational group. METHODS: Baseline UK Biobank data (2006-10) for England were linked to SARS-CoV-2 test results from Public Health England (16 March to 26 July 2020). Included participants were employed or self-employed at baseline, alive and aged <65 years in 2020. Poisson regression models were adjusted sequentially for baseline demographic, socioeconomic, work-related, health, and lifestyle…
Ethnic and socioeconomic differences in Sars-CoV-2 infection
Association of High-Density Lipoprotein Cholesterol With Cognitive Function
Objective: We aimed to examine whether variability in high-density lipoprotein cholesterol (HDL-c) over time was associated with cognitive function. Method: We conducted a post hoc analysis of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) trial. Our sample included 4,428 participants with at least two repeated HDL-c measures between Months 3 and 24 postbaseline and with cognitive assessments at Month 30. HDL-c variability …
ESC/ESH Guidelines for the management of arterial hypertension
The current background information and detailed discussion of the data can be found in ESC CardioMed - Section 44 Systemic hypertension ... ... Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in selecting the best management strategies for an individual patient with a given condition. Guidelines and their recommendations should facilitate decision making of health professionals in their daily pr…
Risk thresholds for alcohol consumption
BACKGROUND: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. METHODS: We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-inco…
Response to
No abstract available
Changes in marital quality over 6 years and its association with cardiovascular disease risk factors in men
BACKGROUND: Marital relationship quality has been suggested to have independent effects on cardiovascular health outcomes. This study investigates the association between changes in marital relationship quality and cardiovascular disease (CVD) risk factors in men. METHODS: We used data from The Avon Longitudinal Study of Parents and Children, a prospective birth cohort study (Bristol, UK). Our baseline sample was restricted to married study fathe…
Body-mass index and all-cause mortality
European Guidelines on cardiovascular disease prevention in clinical practice
No abstract available.
Study protocol of European Fans in Training (EuroFIT)
81935608 . Registered 16 June 2015
Association of Cardiometabolic Multimorbidity With Mortality
IMPORTANCE The prevalence of cardiometabolic multimorbidity is increasing. OBJECTIVE To estimate reductions in life expectancy associated with cardiometabolic multimorbidity. DESIGN, SETTING, AND PARTICIPANTS Age-and sex-adjusted mortality rates and hazard ratios (HRs) were calculated using individual participant data from the Emerging Risk Factors Collaboration (689 300 participants; 91 cohorts; years of baseline surveys: 1960-2007; latest morta…
Genetic studies of body mass index yield new insights for obesity biology
Associations of mutually exclusive categories of physical activity and sedentary time with markers of cardiometabolic health in English adults
In this national sample of English adults, being physically active was associated with a better health profile, even in those with concomitant high sedentary time. Low sedentary time independent of physical activity had a positive association with HDL-cholesterol
Culturally adapting the prevention of diabetes and obesity in South Asians (Podosa) trial
Type 2 diabetes is extremely common in South Asians, e.g. in men from Pakistani and Indian populations it is about three times as likely as in the general population in England, despite similarities in body mass index. Lifestyle interventions reduce the incidence of diabetes. Trials in Europe and North America have not, however, reported on the impact on South Asian populations separately or provided the details of their cross-cultural adaptation…
Socioeconomic Deprivation and Cortical Morphology
OBJECTIVE: Neighborhood-level socioeconomic deprivation has been associated with poor cognitive function pertaining to language and the executive control. Few studies have explored the cortical morphology of regions most commonly associated with these functions. The aim of this study was to examine the association between neighborhood-level deprivation and the morphology of cortical regions associated with language and executive control in adults…
UK-born Pakistani-origin infants are relatively more adipose than white British infants
BACKGROUND: Previous studies have shown markedly lower birth weight among infants of South Asian origin compared with those of White European origin. Whether such differences mask greater adiposity in South Asian infants and whether they persist across generations in contemporary UK populations is unclear. Our aim was to compare birth weight, skinfold thickness and cord leptin between Pakistani and White British infants and to investigate the exp…
Leptin Levels and Depressive Symptoms in People With Type 2 Diabetes
OBJECTIVE: Depression in Type 2 diabetes is associated with obesity, cardiovascular disease, and mortality. Leptin is a plausible mediating factor because it has been related to obesity, depression, and cardiovascular disease in nondiabetic populations. We sought to assess whether leptin is related to depressive symptoms in people with Type 2 diabetes. METHODS: One thousand fifty-seven subjects (48.5% women, mean [standard deviation] age = 67.9 […
Early life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive performance
Adverse levels of biomarkers of ill health in adults appear to be influenced by father's occupation and childhood home conditions. Chronic inflammation and endothelial activation may in part act as intermediary phenotypes in this complex relationship. Reducing the 'health divide' requires that these life course determinants are taken into account
P2-330 Associations of 25-hydroxyvitamin D2 and D3 with cardiovascular risk factors in childhood
Introduction Some observational studies have associated low vitamin D status with increased cardiovascular disease (CVD) and risk factors in adults, but results from randomised controlled trials suggest these associations may not be causal. Trials have largely used supplementation with vitamin D2 and the availability of D3 supplements has led to the suggestion that this is more potent and null effects in previous trials may be because of inadequa…
O1-2.4 Hypertensive disorders of pregnancy and offspring vascular, inflammatory and lipid outcomes in childhood
Introduction Offspring of hypertensive pregnancies have higher blood pressure (BP) in later life. Whether this is accompanied by impaired vascular function and worse cardiovascular risk profiles suggesting mediation by intrauterine exposure to vascular toxins and long term programming, or is restricted to hypertension consistent with a genetic predisposition, is unknown. Specificity of association would be a useful test of these alternatives. Met…
Ethnic differences in type 2 diabetes risk markers in children in the UK are not explained by socio-economic status
Objectives To examine the influence of socio-economic position on type 2 diabetes risk markers in different ethnic groups and determine whether differences in socio-economic position can explain ethnic differences in type 2 diabetes risk. Design Cross-sectional survey of children in 200 primary schools in London, Birmingham and Leicester (Child Heart and Health Study England, or CHASE) in which standardised anthropometric and fasting blood measur…
Prediction scores to identify older adults at high risk for type 2 diabetes
The greatest relative increase in type 2 diabetes (T2DM) prevalence in developed countries thought likely to occur over the next 25 years will be in the over 65 age group. The aim of this study was to examine the effectiveness of both simple strategies based on simple clinical parameters (suitable for use in primary care) and more complex scores involving blood markers to identify older individuals at high risk of developing T2DM. A
Changes in marital quality over 6 years and its association with cardiovascular disease risk factors in men
BACKGROUND: Marital relationship quality has been suggested to have independent effects on cardiovascular health outcomes. This study investigates the association between changes in marital relationship quality and cardiovascular disease (CVD) risk factors in men. METHODS: We used data from The Avon Longitudinal Study of Parents and Children, a prospective birth cohort study (Bristol, UK). Our baseline sample was restricted to married study fathe…
UK-born Pakistani-origin infants are relatively more adipose than white British infants
BACKGROUND: Previous studies have shown markedly lower birth weight among infants of South Asian origin compared with those of White European origin. Whether such differences mask greater adiposity in South Asian infants and whether they persist across generations in contemporary UK populations is unclear. Our aim was to compare birth weight, skinfold thickness and cord leptin between Pakistani and White British infants and to investigate the exp…
Psychological, social and biological determinants of ill health (pSoBid)
This cross-sectional study recruited the planned sample of subjects from least deprived and most deprived areas within Glasgow. As evident in other studies response differed between the most and least deprived areas. This study brought together researchers/academics from diverse disciplines to build a more sophisticated understanding of the determinants of health inequalities than can be achieved through unidisciplinary approaches. Future analyse…
Prediction scores to identify older adults at high risk for type 2 diabetes
The greatest relative increase in type 2 diabetes (T2DM) prevalence in developed countries thought likely to occur over the next 25 years will be in the over 65 age group. The aim of this study was to examine the effectiveness of both simple strategies based on simple clinical parameters (suitable for use in primary care) and more complex scores involving blood markers to identify older individuals at high risk of developing T2DM. A
Ethnic differences in type 2 diabetes risk markers in children in the UK are not explained by socio-economic status
Objectives To examine the influence of socio-economic position on type 2 diabetes risk markers in different ethnic groups and determine whether differences in socio-economic position can explain ethnic differences in type 2 diabetes risk. Design Cross-sectional survey of children in 200 primary schools in London, Birmingham and Leicester (Child Heart and Health Study England, or CHASE) in which standardised anthropometric and fasting blood measur…
Early life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive performance
Adverse levels of biomarkers of ill health in adults appear to be influenced by father's occupation and childhood home conditions. Chronic inflammation and endothelial activation may in part act as intermediary phenotypes in this complex relationship. Reducing the 'health divide' requires that these life course determinants are taken into account
P2-330 Associations of 25-hydroxyvitamin D2 and D3 with cardiovascular risk factors in childhood
Introduction Some observational studies have associated low vitamin D status with increased cardiovascular disease (CVD) and risk factors in adults, but results from randomised controlled trials suggest these associations may not be causal. Trials have largely used supplementation with vitamin D2 and the availability of D3 supplements has led to the suggestion that this is more potent and null effects in previous trials may be because of inadequa…
O1-2.4 Hypertensive disorders of pregnancy and offspring vascular, inflammatory and lipid outcomes in childhood
Introduction Offspring of hypertensive pregnancies have higher blood pressure (BP) in later life. Whether this is accompanied by impaired vascular function and worse cardiovascular risk profiles suggesting mediation by intrauterine exposure to vascular toxins and long term programming, or is restricted to hypertension consistent with a genetic predisposition, is unknown. Specificity of association would be a useful test of these alternatives. Met…
Leptin Levels and Depressive Symptoms in People With Type 2 Diabetes
OBJECTIVE: Depression in Type 2 diabetes is associated with obesity, cardiovascular disease, and mortality. Leptin is a plausible mediating factor because it has been related to obesity, depression, and cardiovascular disease in nondiabetic populations. We sought to assess whether leptin is related to depressive symptoms in people with Type 2 diabetes. METHODS: One thousand fifty-seven subjects (48.5% women, mean [standard deviation] age = 67.9 […
Socioeconomic Deprivation and Cortical Morphology
OBJECTIVE: Neighborhood-level socioeconomic deprivation has been associated with poor cognitive function pertaining to language and the executive control. Few studies have explored the cortical morphology of regions most commonly associated with these functions. The aim of this study was to examine the association between neighborhood-level deprivation and the morphology of cortical regions associated with language and executive control in adults…
UK-born Pakistani-origin infants are relatively more adipose than white British infants
BACKGROUND: Previous studies have shown markedly lower birth weight among infants of South Asian origin compared with those of White European origin. Whether such differences mask greater adiposity in South Asian infants and whether they persist across generations in contemporary UK populations is unclear. Our aim was to compare birth weight, skinfold thickness and cord leptin between Pakistani and White British infants and to investigate the exp…
Culturally adapting the prevention of diabetes and obesity in South Asians (Podosa) trial
Type 2 diabetes is extremely common in South Asians, e.g. in men from Pakistani and Indian populations it is about three times as likely as in the general population in England, despite similarities in body mass index. Lifestyle interventions reduce the incidence of diabetes. Trials in Europe and North America have not, however, reported on the impact on South Asian populations separately or provided the details of their cross-cultural adaptation…
Association of Cardiometabolic Multimorbidity With Mortality
IMPORTANCE The prevalence of cardiometabolic multimorbidity is increasing. OBJECTIVE To estimate reductions in life expectancy associated with cardiometabolic multimorbidity. DESIGN, SETTING, AND PARTICIPANTS Age-and sex-adjusted mortality rates and hazard ratios (HRs) were calculated using individual participant data from the Emerging Risk Factors Collaboration (689 300 participants; 91 cohorts; years of baseline surveys: 1960-2007; latest morta…
Genetic studies of body mass index yield new insights for obesity biology
Associations of mutually exclusive categories of physical activity and sedentary time with markers of cardiometabolic health in English adults
In this national sample of English adults, being physically active was associated with a better health profile, even in those with concomitant high sedentary time. Low sedentary time independent of physical activity had a positive association with HDL-cholesterol
Body-mass index and all-cause mortality
European Guidelines on cardiovascular disease prevention in clinical practice
No abstract available.
Study protocol of European Fans in Training (EuroFIT)
81935608 . Registered 16 June 2015
Changes in marital quality over 6 years and its association with cardiovascular disease risk factors in men
BACKGROUND: Marital relationship quality has been suggested to have independent effects on cardiovascular health outcomes. This study investigates the association between changes in marital relationship quality and cardiovascular disease (CVD) risk factors in men. METHODS: We used data from The Avon Longitudinal Study of Parents and Children, a prospective birth cohort study (Bristol, UK). Our baseline sample was restricted to married study fathe…
ESC/ESH Guidelines for the management of arterial hypertension
The current background information and detailed discussion of the data can be found in ESC CardioMed - Section 44 Systemic hypertension ... ... Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in selecting the best management strategies for an individual patient with a given condition. Guidelines and their recommendations should facilitate decision making of health professionals in their daily pr…
Risk thresholds for alcohol consumption
BACKGROUND: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. METHODS: We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-inco…
Response to
No abstract available
Ethnic and socioeconomic differences in Sars-CoV-2 infection
Association of High-Density Lipoprotein Cholesterol With Cognitive Function
Objective: We aimed to examine whether variability in high-density lipoprotein cholesterol (HDL-c) over time was associated with cognitive function. Method: We conducted a post hoc analysis of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) trial. Our sample included 4,428 participants with at least two repeated HDL-c measures between Months 3 and 24 postbaseline and with cognitive assessments at Month 30. HDL-c variability …
ESC Guidelines on cardiovascular disease prevention in clinical practice
The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of their publication. The ESC is not responsible in the event of any contradiction, discrepancy and/or ambiguity between the ESC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to goo…
Occupation and risk of severe Covid-19
OBJECTIVES: To investigate severe COVID-19 risk by occupational group. METHODS: Baseline UK Biobank data (2006-10) for England were linked to SARS-CoV-2 test results from Public Health England (16 March to 26 July 2020). Included participants were employed or self-employed at baseline, alive and aged <65 years in 2020. Poisson regression models were adjusted sequentially for baseline demographic, socioeconomic, work-related, health, and lifestyle…
Identifying the Biomarker Profile of Pre-Frail and Frail People
Several biomarkers were linked to pre-frailty and frailty. Nonetheless, some of the associations differed by sex. Our findings contribute to a broader understanding of the pathophysiology of frailty as currently defined
Medicine (23 works) · Internal Medicine (11 works) · Environmental health (10 works) · Internal Medicine (10 works) · Population (10 works) · Gerontology (9 works) · Endocrinology (8 works) · Pathology (7 works) · Demography (6 works) · Diabetes mellitus (6 works)