Ian B Hickie
Datos Biográficos
| ID | 5548280 |
|---|---|
| NOMBRE | Ian B Hickie |
| NOMBRES | Ian B |
| APELLIDO | Hickie |
| FIRMA | HICKIE I B |
| AFILIACIONES | The University of Sydney |
| ORCID | 0000-0001-8832-9895 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 44 |
| TOTAL DE CITAS | 1 |
| TOTAL COMO AUTOR | 44 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2004 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 1 |
Following the youth patient journey in the mental health help-seeking process in Bogotá, Colombia
BACKGROUND: Understanding help-seeking behaviors of young people with mental health concerns is crucial for developing responsive mental health services and policies. This study aimed to explore the help-seeking journeys of Colombian youth, the formal and informal services they reached out to when faced with psychological distress and the order in which these services were consulted. Additionally, it examined the differences between pathways of a…
Evaluating placebo responses to intranasal oxytocin in autism
BACKGROUND: The placebo effect is established in clinical trials, but for paediatric research, questions remain about how to best manage its influence. Within the autism field, data on these issues is sparse. This is particularly important in the oxytocin field where placebo responses are thought to play an important role. This study reports on data from the single-blind, placebo lead-in phase of a randomised controlled trial (RCT) to investigate…
One Eye Open
BACKGROUND: The integration of lived experience within mental health research remains inconsistent, with many models positioning lived experience in advisory rather than embedded roles. This can limit meaningful engagement and reduce the relevance and translational impact of research. APPROACH: Drawing on an ongoing five-year Welcome Trust-funded programme investigating sleep and circadian rhythm disturbances in youth-onset mood disorders, this v…
Cross-cultural similarities and variations in parent-child value transmission in low- and middle-income countries
Diverse global cultures have different value definitions, meanings, and orientations. Yet, some values are shared across societies, varying in importance in each context. Values that the current generation of parents strive to pass on to the next generation are context-laden, evolving, and varying in conceptualisation worldwide. Subsequently, to advance cultural humility and value sensitivity, early childhood development (ECD) information, progra…
Multistakeholder perspectives on children’s play and the systemic factors that influence it across 12 low- and middle-income countries
Children’s play in early childhood is not purely natural and inherent, but shaped by interpersonal, sociocultural, political, and economic factors. Drawing on qualitative data from 74 co-design workshops conducted across 12 low- and middle-income countries, this paper focuses on understanding how children’s play is conceptualised by parents and caregivers and the systems that shape it across diverse settings. Using thematic analysis, two themes, …
Amplifying children’s leadership roles and voice in decision-making through co-production in outside of school hours care
Background There is scant research examining evidence-based processes and practices that delineate how to include the voices of children in service design and delivery in school age care environments such as Outside of School Hours Care (OSHC). A possible structure to support children to share leadership in design of their OSHC program and have a meaningful voice in decision-making is co-production, whereby children and their OSHC communities hav…
Developing a conceptual framework for cultural adaptation of digital parenting interventions
Cultural adaptation is essential for effective implementation of digital parenting interventions across diverse settings, including in low- and middle-income countries. Dominant frameworks for cultural adaptation focus on intervention design components at the expense of attending to processes of adaptation that take place during implementation and neglect the significance of cultural context for measurement and evaluation of outcomes. Despite man…
Parental emotional adjustment as a primary target for parenting programs
A robust literature demonstrates the importance of supporting parents' mental health and emotional adjustment to improve both parent and child outcomes. Our results highlight that better emotional adjustment is associated with more positive parenting practices, suggesting that interventions that support a parent's ability to cope with the parenting role will increase the use of responsive and nurturing childrearing practices. However, further res…
Personalised care, youth mental health, and digital technology
Digital health is typically driven, in part, by the principle of personalised care. However, the underlying values and associated ethical design considerations at the intersection of personalised care, youth mental health, and digital technology are underexplored. Through a value sensitive design lens, this work aims to contribute a prototype conceptual framework for the ethical design and evaluation of personalised youth digital mental health te…
The Lancet Psychiatry Commission on youth mental health
Social and joint attention during shared book reading in young autistic children
BACKGROUND: Atypical patterns of social engagement and joint attention behaviors are diagnostic criteria for people with autism spectrum disorder. Experimental tasks using eye-tracking methodologies have, however, shown inconsistent results. The development of tasks with greater ecological validity and relevance for developmentally appropriate social milestones has been identified as important for the field. METHODS: We developed a novel, dynamic…
Youth Perspectives on ‘Highly Personalised and Measurement‐Based Care’
OBJECTIVES: Despite high levels of mental ill-health amongst young people (aged 15-30), this group demonstrates low help-seeking and high drop-out from mental health services (MHS). Whilst shared decision-making can assist people in receiving appropriate and effective health care, young people frequently report that they do not feel involved in treatment decisions. The current study focused on co-design of a clinical education and participant inf…
Teachers as first responders
The data show that teachers are often placed as first responders when a student has a mental health issue but feel inadequately trained to manage these issues in the classroom. We identified mental health issues presenting in Australian classrooms and documented critical features of mental-health training asked for by teachers in order to address those issues. Given the increasing demands on teachers to address the mental health of children and a…
Childcare in Contemporary Africa
Kinship care and child fostering are a common practice in certain parts of Africa. This narrative review seeks to explore and thematically code the contextual circumstances in which children leave their natal homes and are fostered across Africa and the corresponding outcomes for these children. It draws on case studies from Cameroon, the Democratic Republic of the Congo, Ethiopia, Kenya, and Namibia and other countries across the region to illus…
Risk tolerance in youth with emerging mood disorders
Reward-seeking behavior drives adolescents toward risky decision-making. As compared to their older and younger peers, adolescents experience higher rates of anxiety and depressive disorders, leading to impaired decision-making with negative consequences. At two time points, separated by 6–8 weeks, we measured risky and ambiguous choices concurrently with levels of dysregulated emotion for youth aged 16–25 ( N = 30, mean age 19.22 years, 19 males…
Building systemic resilience, productivity and well-being
Strengthening mental health research outcomes through genuine partnerships with young people with lived or living experience
BACKGROUND: Despite increasing support for stakeholder inclusion in research, there is limited evaluative research to guide safe (i.e., youth-friendly) and meaningful (i.e., non-tokenistic) partnerships with young people with lived experience of mental ill-health in research. This paper describes a pilot evaluation and iterative design of a Youth Lived Experience Working Group (LEWG) protocol that was established by the Youth Mental Health and Te…
Measuring, Modeling, and Forecasting the Mental Wealth of Nations
The COVID-19 pandemic has exposed the deep links and fragility of economic, health and social systems. Discussions of reconstruction include renewed interest in moving beyond GDP and recognizing “human capital”, “brain capital”, “mental capital”, and “wellbeing” as assets fundamental to economic reimagining, productivity, and prosperity. This paper describes how the conceptualization of Mental Wealth provides an important framing for measuring an…
A Dynamic Approach to Economic Priority Setting to Invest in Youth Mental Health and Guide Local Implementation
Equipping SD models to undertake economic analysis is intended to support local priority setting and help optimise implementation regarding the best value mix of investments, timing and scale. The objectives are to improve allocative efficiency, increase mental health and economic productivity
Sound Decision Making in Uncertain Times
The COVID-19 pandemic demonstrated the significant value of systems modelling in supporting proactive and effective public health decision making despite the complexities and uncertainties that characterise an evolving crisis. The same approach is possible in the field of mental health. However, a commonly levelled (but misguided) criticism prevents systems modelling from being more routinely adopted, namely, that the presence of uncertainty arou…
Optimizing Strategies for Improving Mental Health in Victoria, Australia during the Covid-19 Era
The ongoing COVID-19 pandemic has impacted the mental health of populations and highlighted the limitations of mental health care systems. As the trajectory of the pandemic and the economic recovery are still uncertain, decision tools are needed to help evaluate the best interventions to improve mental health outcomes. We developed a system dynamics model that captures causal relationships among population, demographics, post-secondary education,…
Partnering with Aboriginal and Torres Strait Islander Peoples
The social and emotional wellbeing of young Aboriginal and Torres Strait Islander peoples should be supported through an Indigenous-led and community empowering approach. Applying systems thinking via participatory approaches is aligned with Aboriginal and Torres Strait Islander research paradigms and can be an effective method to deliver a decision support tool for mental health systems planning for Indigenous communities. Evaluations are necess…
Participatory Systems Modelling for Youth Mental Health
The youth mental health sector is persistently challenged by issues such as service fragmentation and inefficient resource allocation. Systems modelling and simulation, particularly utilizing participatory approaches, is offering promise in supporting evidence-informed decision making with limited resources by testing alternative strategies in safe virtual environments before implementing them in the real world. However, improved evaluation effor…
Centralisation versus regionalisation
In response to the recent Productivity Commission report into mental health, the previous Federal Government announced its intention to produce a new national agreement that lays the platform for Australia's sixth national mental health plan. It has been recommended mental health move to a more regional model of governance and planning, away from a centralised, top‐down approach, partly in response to broader reforms affecting health care, and pa…
A multidisciplinary approach to evaluate the impact of emotional dysregulation on adolescent decision making
Evaluating decision-making during youth is a complex area of research. Multiple factors influence the young person’s subjective decision-making at this stage of development. Sub-optimal decision-making can have lifelong consequences. Longer adolescence, life stressors, drugs and alcohol and adverse events impact the young person, making them vulnerable to emerging mood disorders, such as anxiety and depression. Behavioural economics with its cogn…
Centralisation versus regionalisation
In response to the recent Productivity Commission report into mental health, the previous Federal Government announced its intention to produce a new national agreement that lays the platform for Australia's sixth national mental health plan. It has been recommended mental health move to a more regional model of governance and planning, away from a centralised, top‐down approach, partly in response to broader reforms affecting health care, and pa…
Influences of Distress and Alcohol Consumption on the Development of a Delayed-Type Hypersensitivity Skin Test Response
OBJECTIVE: This paper reports the effects of naturally occurring levels of distress on the development of delayed-type hypersensitivity (DTH) skin test responses. These in vivo measures provide a biologically relevant assessment of cellular immune competence. METHODS: Subjects (N = 166) were immunized (baseline) with the novel antigen, keyhole limpet hemocyanin (KLH), and DTH skin test responses against KLH were assessed 3 weeks later (follow-up)…
Two Sides of the Same Coin
The aim of the current study was to delineate the psychiatric profile of cannabis dependent young people (14-29 years old) with mental health problems (N = 36) seeking treatment via a research study. To do so, the Structured Clinical Interview for DSM-IV-TR Axis I Disorders and the Structured Clinical Interview for DSM-IV Childhood Diagnoses were used to obtain DSM-IV diagnoses, while a modified Timeline Followback interview and self-reports were…
Neuropsychological profile according to the clinical stage of young persons presenting for mental health care
The degree of neuropsychological impairment in young persons with mental disorders appears to discriminate those with attenuated syndromes from those with a discrete disorder, independent of diagnostic status and current symptoms. Our findings suggest that neuropsychological assessment is a critical aspect of clinical evaluation of young patients at the early stages of a major psychiatric illness
Associations Between Depression and Anxiety Symptoms and Retinal Vessel Caliber in Adolescents and Young Adults
OBJECTIVE: Previous longitudinal studies suggest that depression and anxiety are associated with risk for cardiovascular disease. The aim of the present study was to test whether an association between depression and anxiety symptoms and retinal vessel caliber, an indicator of subclinical cardiovascular risk, is apparent as early as adolescence and young adulthood. METHODS: Participants were 865 adolescents and young adults who participated in th…
Characterization of Fatigue States in Medicine and Psychiatry by Structured Interview
CONTEXT: Unexplained fatigue states are prevalent, with uncertain diagnostic boundaries. OBJECTIVE: Patients with fatigue-related illnesses were investigated by questionnaire and a novel semistructured interview to identify discriminatory features. METHODS: Cross-sectional samples of women from specialist practices with chronic fatigue syndrome (n = 20), postcancer fatigue (PCF; n = 20), or major depression (n = 16) were recruited. Additionally, …
EHealth integrated interventions for MH
Australia is an innovator in the development of e health interventions for mental health conditions, such as anxiety, depression, PTSD, suicide risk, and comorbidity with drug and alcohol problems. E mental health is cost effecitve, able to be delivered into a range of settings, including health, education and community contexts, works for mild to moderate as well as more severe mental health conditions. Importantly, e health solutions are likely…
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Parallel Changes in Mood and Melatonin Rhythm Following an Adjunctive Multimodal Chronobiological Intervention With Agomelatine in People With Depression
Background: Agomelatine is a melatonin agonist and 5HT antagonist developed for the treatment of major depressive disorder which also has some effects on the circadian system. Since circadian dysfunctions are thought to play a role in the pathophysiology of depression, some of the mechanism of action of this drug may relate to improvements in circadian rhythms. Objective: This proof of concept open-label study sought to determine if improvements …
A Digital Platform Designed for Youth Mental Health Services to Deliver Personalized and Measurement-Based Care
Mental disorders that commonly emerge during adolescence and young adulthood are associated with substantial immediate burden and risks, as well as potentially imparting lifetime morbidity and premature mortality. While the development of health services that are youth focused and prioritize early intervention has been a critical step forward, an ongoing challenge is the heterogeneous nature of symptom profiles and illness trajectories. Consequen…
The Impact of Reducing Psychiatric Beds on Suicide Rates
There has been ongoing debate regarding the impact of reductions in psychiatric beds on suicide rates, and the potential effect of reallocation of acute hospital funding to community-based mental health programs and services. Computer simulation offers significant value in advancing such debate by providing a robust platform for exploring strategic resource allocation scenarios before they are implemented in the real world. We report an applicati…
The Science of Complex Systems Is Needed to Ameliorate the Impacts of Covid-19 on Mental Health
Jo-An Atkinson1,2*Yun Ju Christine Song1Kathleen R. Merikangas3Adam Skinner1Ante Prodan1,2,4Frank Iorfino1Louise Freebairn1,5Danya Rose1Nicholas Ho1Jacob Crouse1Vadim Zipunnikov6Ian B. Hickie1
Machine Learning for Differential Diagnosis Between Clinical Conditions With Social Difficulty
Differential diagnosis in adult cohorts with social difficulty is confounded by comorbid mental health conditions, common etiologies, and shared phenotypes. Identifying shared and discriminating profiles can facilitate intervention and remediation strategies. The objective of the study was to identify salient features of a composite test battery of cognitive and mood measures using a machine learning paradigm in clinical cohorts with social inter…
Bringing new tools, a regional focus, resource-sensitivity, local engagement and necessary discipline to mental health policy and planning
Systems modelling and simulation delivers an interactive decision analytic tool to test mental health reform and service planning scenarios in a safe environment before implementing them in the real world. The approach drives better decision-making and can inform the scale up of effective and contextually relevant strategies to reduce the burden of mental disorder and enhance the mental wealth of nations
A multidisciplinary approach to evaluate the impact of emotional dysregulation on adolescent decision making
Evaluating decision-making during youth is a complex area of research. Multiple factors influence the young person’s subjective decision-making at this stage of development. Sub-optimal decision-making can have lifelong consequences. Longer adolescence, life stressors, drugs and alcohol and adverse events impact the young person, making them vulnerable to emerging mood disorders, such as anxiety and depression. Behavioural economics with its cogn…
Right Care, First Time
Most mental disorders emerge before the age of 25 years and, if left untreated, have the potential to lead to considerable lifetime burden of disease. Many services struggle to manage high demand and have difficulty matching individuals to timely interventions due to the heterogeneity of disorders. The technological implementation of clinical staging for youth mental health may assist the early detection and treatment of mental disorders. We desc…
Potential Genetic Overlap Between Insomnia and Sleep Symptoms in Major Depressive Disorder
Background: The prevalence of insomnia and hypersomnia in depressed individuals is substantially higher than that found in the general population. Unfortunately, these concurrent sleep problems can have profound effects on the disease course. Although the full biology of sleep remains to be elucidated, a recent genome-wide association (GWAS) of insomnia, and other sleep traits in over 1 million individuals was recently published and provides many…
Comorbid Chronic Pain and Depression
The bidirectional relationship between depression and chronic pain is well-recognized, but their clinical management remains challenging. Here we characterize the shared risk factors and outcomes for their comorbidity in the Australian Genetics of Depression cohort study ( N = 13,839). Participants completed online questionnaires about chronic pain, psychiatric symptoms, comorbidities, treatment response and general health. Logistic regression mo…
Which Social, Economic, and Health Sector Strategies Will Deliver the Greatest Impacts for Youth Mental Health and Suicide Prevention? Protocol for an Advanced, Systems Modelling Approach
Background: Current global challenges are generating extensive social disruption and uncertainty that have the potential to undermine the mental health, wellbeing, and futures of young people. The scale and complexity of challenges call for engagement with systems science-based decision analytic tools that can capture the dynamics and interrelationships between physical, social, economic, and health systems, and support effective national and reg…
An implementation science protocol for technology-enabled person-centred mental health services reform
The International Journal of Integrated Care (IJIC) is an online, open-access, peer-reviewed scientific journal that publishes original articles in the field of integrated care on a continuous basis.IJIC has an Impact Factor of 5.120 (2020 JCR, received in June 2021)The IJIC 20th Anniversary Issue was published in 2021
Technology-enabled service models for quality improvements in Australian mental health care delivery
The International Journal of Integrated Care (IJIC) is an online, open-access, peer-reviewed scientific journal that publishes original articles in the field of integrated care on a continuous basis.IJIC has an Impact Factor of 5.120 (2020 JCR, received in June 2021)The IJIC 20th Anniversary Issue was published in 2021
Measuring, Modeling, and Forecasting the Mental Wealth of Nations
The COVID-19 pandemic has exposed the deep links and fragility of economic, health and social systems. Discussions of reconstruction include renewed interest in moving beyond GDP and recognizing “human capital”, “brain capital”, “mental capital”, and “wellbeing” as assets fundamental to economic reimagining, productivity, and prosperity. This paper describes how the conceptualization of Mental Wealth provides an important framing for measuring an…
A Dynamic Approach to Economic Priority Setting to Invest in Youth Mental Health and Guide Local Implementation
Equipping SD models to undertake economic analysis is intended to support local priority setting and help optimise implementation regarding the best value mix of investments, timing and scale. The objectives are to improve allocative efficiency, increase mental health and economic productivity
Sound Decision Making in Uncertain Times
The COVID-19 pandemic demonstrated the significant value of systems modelling in supporting proactive and effective public health decision making despite the complexities and uncertainties that characterise an evolving crisis. The same approach is possible in the field of mental health. However, a commonly levelled (but misguided) criticism prevents systems modelling from being more routinely adopted, namely, that the presence of uncertainty arou…
Optimizing Strategies for Improving Mental Health in Victoria, Australia during the Covid-19 Era
The ongoing COVID-19 pandemic has impacted the mental health of populations and highlighted the limitations of mental health care systems. As the trajectory of the pandemic and the economic recovery are still uncertain, decision tools are needed to help evaluate the best interventions to improve mental health outcomes. We developed a system dynamics model that captures causal relationships among population, demographics, post-secondary education,…
Partnering with Aboriginal and Torres Strait Islander Peoples
The social and emotional wellbeing of young Aboriginal and Torres Strait Islander peoples should be supported through an Indigenous-led and community empowering approach. Applying systems thinking via participatory approaches is aligned with Aboriginal and Torres Strait Islander research paradigms and can be an effective method to deliver a decision support tool for mental health systems planning for Indigenous communities. Evaluations are necess…
Psychology (28 obras) · Medicine (27 obras) · Psychiatry (26 obras) · Mental health (25 obras) · Child and Adolescent Psychosocial and Emotional Development (10 obras) · Clinical Psychology (10 obras) · Anxiety (7 obras) · Computer Science (7 obras) · Economics (7 obras) · Health Policy Implementation Science (7 obras)