Lawrence K Duffy
Biographic Data
| ID | 5592268 |
|---|---|
| NAME | Lawrence K Duffy |
| GIVEN NAMES | Lawrence K |
| FAMILY NAME | Duffy |
| SIGNATURE | DUFFY L K |
| AFFILIATIONS | University of Alaska Fairbanks |
| ORCID | 0000-0002-6336-3138 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 3 |
| WORKS AS AUTHOR | 9 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1987 |
| LATEST PUBLICATION YEAR | 2016 |
| H-INDEX | 1 |
Iḷisaġvik Tribal College’s summer climate program
The incorporation of informal science modules with traditional ecological knowledge (TEK) engages students in Science, Technology, Engineering, and Mathematics (STEM) courses. During the summers 2012–2015, Iḷisaġvik Tribal College, located in Barrow, AK, hosted an average of 12 rural Alaska Native middle-school and high school students per year in the college’s summer STEM program called “Climate and Permafrost Changes on the North Slope: In Cult…
Glucose transporter-4 in white blood cells of young and old sled dogs
The insulin responsive glucose transporter, GLUT4 is found predominantly in muscle and adipose cells. Maratou and others (2007) reported that there is GLUT4 in white blood cells (WBC) collected from human subjects in response to insulin activation. This study was designed to validate the presence of GLUT4 in white blood cells of sled dogs and furthermore to investigate whether changes in levels of the GLUT4 protein might be associated with aging.…
Bias, complexity, and uncertainty in ecosystem risk assessment
Because thousands of pharmaceutical and industrial compounds are in use today and distributed into ecosystems via waste water, effective analysis of environmental risk needs to change as our understanding of the complexity of ecosystem services grows. Klaminder et al (2014 Environ. Res. Lett. http://dx.doi.org/10.1088/1748-9326/9/8/084003 9 http://dx.doi.org/10.1088/1748-9326/9/8/084003 ) now provide some important observations on a methodologica…
Selected plasma fatty acid levels in subsistence fed sled dogs along the Yukon River
The introduction of the ‘western diet’ marked a decline in omega–3 fatty acids rich foods and a concurrent increase in saturated and omega–6 fatty acids that persists today. Historically, circumpolar people have had a low incidence of obesity, diabetes and cardiovascular disease and this has been largely attributed to polyphenolic compounds and omega–3 fatty acids offered from subsistence foods. In this report, we studied sled dogs as an Arctic s…
Mercury interferes with endogenous antioxidant levels in Yukon River subsistence-fed sled dogs
Before adopting modern corn-and-grain-based western processed diets, circumpolar people had a high fat and protein subsistence diet and exhibited a low incidence of obesity, diabetes and cardiovascular disease. Some health benefits are attributable to a subsistence diet that is rich in omega-3 fatty acids and antioxidants. Pollution, both global and local, is a threat to wild foods, as it introduces contaminants into the food system. Northern ind…
Mercury in lichens and reindeer hair from Alaska
Reindeer and caribou are terrestrial herbivores, that feed on lichens and are used for commercial and subsistence food products. Caribou are a key component of the arctic food web and the bioaccumulation of toxic contaminants, such as mercury (Hg), needs to be monitored to establish a baseline as the arctic environment is impacted by both climate change and future industrial development. A changing climate in Alaska is influencing plant species c…
Multi-generation health risks of persistent organic pollution in the far north
Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity
These results support the hypothesis that melatonin is a neuroprotective antioxidant. Our data also suggest that 1 mM melatonin may have detrimental effects
Prosimian hemoglobins
The ring‐tailed lemur, Lemur catta , shows a two‐component hemoglobin phenotype after alkaline electrophoresis. A difference in the amino acid sequence of the isolated α‐globins was observed at position 15 (α I‐Gly, α II‐Lys) and can account for the electrophoretic pattern of two hemoglobin components. Only one other amino acid difference was found in the sequence of the two globin chains: a neutral substitution occurs at position 53 (α I‐Gly, α …
Prosimian hemoglobins
The ring‐tailed lemur, Lemur catta , shows a two‐component hemoglobin phenotype after alkaline electrophoresis. A difference in the amino acid sequence of the isolated α‐globins was observed at position 15 (α I‐Gly, α II‐Lys) and can account for the electrophoretic pattern of two hemoglobin components. Only one other amino acid difference was found in the sequence of the two globin chains: a neutral substitution occurs at position 53 (α I‐Gly, α …
Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity
These results support the hypothesis that melatonin is a neuroprotective antioxidant. Our data also suggest that 1 mM melatonin may have detrimental effects
Multi-generation health risks of persistent organic pollution in the far north
Mercury in lichens and reindeer hair from Alaska
Reindeer and caribou are terrestrial herbivores, that feed on lichens and are used for commercial and subsistence food products. Caribou are a key component of the arctic food web and the bioaccumulation of toxic contaminants, such as mercury (Hg), needs to be monitored to establish a baseline as the arctic environment is impacted by both climate change and future industrial development. A changing climate in Alaska is influencing plant species c…
Mercury interferes with endogenous antioxidant levels in Yukon River subsistence-fed sled dogs
Before adopting modern corn-and-grain-based western processed diets, circumpolar people had a high fat and protein subsistence diet and exhibited a low incidence of obesity, diabetes and cardiovascular disease. Some health benefits are attributable to a subsistence diet that is rich in omega-3 fatty acids and antioxidants. Pollution, both global and local, is a threat to wild foods, as it introduces contaminants into the food system. Northern ind…
Selected plasma fatty acid levels in subsistence fed sled dogs along the Yukon River
The introduction of the ‘western diet’ marked a decline in omega–3 fatty acids rich foods and a concurrent increase in saturated and omega–6 fatty acids that persists today. Historically, circumpolar people have had a low incidence of obesity, diabetes and cardiovascular disease and this has been largely attributed to polyphenolic compounds and omega–3 fatty acids offered from subsistence foods. In this report, we studied sled dogs as an Arctic s…
Bias, complexity, and uncertainty in ecosystem risk assessment
Because thousands of pharmaceutical and industrial compounds are in use today and distributed into ecosystems via waste water, effective analysis of environmental risk needs to change as our understanding of the complexity of ecosystem services grows. Klaminder et al (2014 Environ. Res. Lett. http://dx.doi.org/10.1088/1748-9326/9/8/084003 9 http://dx.doi.org/10.1088/1748-9326/9/8/084003 ) now provide some important observations on a methodologica…
Glucose transporter-4 in white blood cells of young and old sled dogs
The insulin responsive glucose transporter, GLUT4 is found predominantly in muscle and adipose cells. Maratou and others (2007) reported that there is GLUT4 in white blood cells (WBC) collected from human subjects in response to insulin activation. This study was designed to validate the presence of GLUT4 in white blood cells of sled dogs and furthermore to investigate whether changes in levels of the GLUT4 protein might be associated with aging.…
Iḷisaġvik Tribal College’s summer climate program
The incorporation of informal science modules with traditional ecological knowledge (TEK) engages students in Science, Technology, Engineering, and Mathematics (STEM) courses. During the summers 2012–2015, Iḷisaġvik Tribal College, located in Barrow, AK, hosted an average of 12 rural Alaska Native middle-school and high school students per year in the college’s summer STEM program called “Climate and Permafrost Changes on the North Slope: In Cult…
Biology (7 works) · Ecology (6 works) · Geography (4 works) · Indigenous Studies and Ecology (4 works) · Arctic (3 works) · Biochemistry (3 works) · Chemistry (3 works) · Endocrinology (3 works) · Medicine (3 works) · Agriculture (2 works)