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Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity

Bibliographic Data

ID15048609
AuthorsKimberly L Clapp-Lilly, Mark A Smith (0000-0003-1474-5225), George Perry (0000-0002-6547-0172), Peggy L Harris, Xiongwei Zhu, Kelly L Drew, Lawrence K Duffy (0000-0002-6336-3138)
Year2002
Volume61
Issue1
Pages32-40
Publication date2002-03-01
Open AccessYes
TypeARTICLE
VenueInternational Journal of Circumpolar Health (JOURNAL)
Journal identifiersISSN: 1239-9736 • E-ISSN: 2242-3982
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.3402/ijch.v61i1.17403
PMID12002945
OpenAlexW2010985312
LanguageEN

These results support the hypothesis that melatonin is a neuroprotective antioxidant. Our data also suggest that 1 mM melatonin may have detrimental effects

Antioxidant · Central nervous system · Excitotoxicity · Melatonin · Neuroprotection · NMDA receptor · Oxidative stress · Pro-oxidant · Receptor · Slice preparation · Chemistry · Circadian rhythm and melatonin · Medicine · Mitochondrial Function and Pathology · Neurological Disease Mechanisms and Treatments · Biochemistry · Endocrinology · Internal Medicine · Pharmacology

Highly citedNo

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