Hiroshi Nishiura
Biographic Data
| ID | 6162470 |
|---|---|
| NAME | Hiroshi Nishiura |
| GIVEN NAMES | Hiroshi |
| FAMILY NAME | Nishiura |
| SIGNATURE | NISHIURA H |
| AFFILIATIONS | Hokkaido University |
| ORCID | 0000-0003-0941-8537 |
| VERIFIED | Yes |
| TOTAL WORKS | 15 |
| TOTAL CITATIONS | 2 |
| WORKS AS AUTHOR | 15 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2004 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
A susceptible cluster in a religious camp allowed 2018–2019 measles outbreak in Japan
Objectives: We analyzed the 2018-2019 outbreak of measles in Japan, which started with a gathering at a religious youth camp in Mie, a prefecture located in the central part of Japan. Methods: A retrospective secondary analysis of cases from December 2018 to January 2019 was carried out. The index case was a Japanese man in his 20s living in Wakayama, a prefecture adjacent to Mie Prefecture. As part of his religious activities, he attended a yout…
Night-time population consistently explains the transmission dynamics of coronavirus disease 2019 in three megacities in Japan
Background: Mobility data are crucial for understanding the dynamics of coronavirus disease 2019 (COVID-19), but the consistency of the usefulness of these data over time has been questioned. The present study aimed to reveal the relationship between the transmissibility of COVID-19 in Tokyo, Osaka, and Aichi prefectures and the daily night-time population in metropolitan areas belonging to each prefecture. Methods: population in downtown areas e…
Possible adaptation measures for climate change in preventing heatstroke among older adults in Japan
Introduction: Heatstroke mortality is highest among older adults aged 65 years and older, and the risk is even doubled among those aged 75 years and older. The incidence of heatstroke is expected to increase in the future with elevated temperatures owing to climate change. In the context of a super-aged society, we examined possible adaptation measures in Japan that could prevent heatstroke among older people using an epidemiological survey combi…
Quantifying the future risk of dengue under climate change in Japan
Background In metropolitan Tokyo in 2014, Japan experienced its first domestic dengue outbreak since 1945. The objective of the present study was to quantitatively assess the future risk of dengue in Japan using climate change scenarios in a high-resolution geospatial environment by building on a solid theory as a baseline in consideration of future adaptation strategies. Methods Using climate change scenarios of the Model for Interdisciplinary R…
Age-Dependent Risks of Covid-19 Putatively Caused by Variant Alpha in Japan
Background: Osaka, the third largest prefecture in Japan, experienced a rapid replacement of preexisting strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by variant alpha during March-April 2021. Assessing the burden of variant alpha on health centers and medical institutions is vital to anticipating the surge of patients. The present study aimed to estimate the age-dependent risks of coronavirus disease (COVID-19) putative…
Ambulance Transport of Patients with Mild Conditions in Hokkaido, Japan
Understanding the epidemiological distributions of ambulance transport for patients with mild conditions according to age, disease, and geographic region could help in achieving optimal use of ambulance services. In the present study, we explored the descriptive epidemiology of ambulance transports in Hokkaido, the northernmost prefecture of Japan, identifying potential factors that determine the frequency of transports for mild diseases. Of the …
Modelling a Supplementary Vaccination Program of Rubella Using the 2012–2013 Epidemic Data in Japan
From 2012-2013, Japan experienced a major epidemic of rubella, involving a total of 12,614 rubella cases and 45 confirmed cases of congenital rubella syndrome (CRS). One of the contributory factors in this outbreak may have been that the majority of adult males remained unvaccinated. To plan for a supplementary immunization program (SIP) to elevate the herd immunity level, it is critical to determine the required amount of vaccine and identify th…
Interaction Among Influenza Viruses A/H1N1, A/H3N2, and B in Japan
Seasonal influenza epidemics occur each winter season in temperate zones, involving up to 650,000 deaths each year globally. A published study demonstrated that the circulation of one influenza virus type during early influenza season in the United States interferes with the activity of other influenza virus types. However, this finding has yet to be validated in other settings. In the present work, we investigated the interaction among seasonal …
Fluoroquinolone consumption and Escherichia coli resistance in Japan
Fluoroquinolone consumption and levofloxacin-resistant E. coli are potentially associated on a nationwide scale. The relationship between the two must be elucidated using additional studies with different epidemiological designs, so that any possible counter-measures, including alternative prescription, can be considered in the future
Environmental Drivers of Bacillus-Positive Blood Cultures in a Cancer Hospital, Sapporo, Japan
The Bacillus species is a well-documented causative pathogen of nosocomial bloodstream infection. The present study aimed to identify climatological variables that are associated with Bacillus -positive blood culture in Sapporo, Japan. All cases with Bacillus -positive blood cultures from January 2011 to December 2016 were retrospectively analysed. Climatological data from 2011 to 2016, including daily mean temperature and absolute humidity, were…
Assessing the Effectiveness and Cost-Benefit of Test-and-Vaccinate Policy for Supplementary Vaccination against Rubella with Limited Doses
Elevating herd immunity level against rubella is essential to prevent congenital rubella syndrome (CRS). Insufficient vaccination coverage left susceptible pockets among adults in Japan, and the outbreak of rubella from 2012 to 2013 resulted in 45 observed CRS cases. Given a limited stock of rubella-containing vaccine (RCV) available, the Japanese government recommended healthcare providers to prioritize vaccination to those confirmed with low le…
Vaccination and Clinical Severity
While contact tracing and case isolation are considered as the first choice of interventions against a smallpox bioterrorist event, their effectiveness under vaccination is questioned, because not only susceptibility of host and infectiousness of case but also the risk of severe clinical manifestations among cases is known to be reduced by vaccine-induced immunity, thereby potentially delaying the diagnosis and increasing mobility among vaccinate…
Correcting the Actual Reproduction Number
The basic reproduction number, R(0), a summary measure of the transmission potential of an infectious disease, is estimated from early epidemic growth rate, but a likelihood-based method for the estimation has yet to be developed. The present study corrects the concept of the actual reproduction number, offering a simple framework for estimating R(0) without assuming exponential growth of cases. The proposed method is applied to the HIV epidemic …
Transmission potential of primary pneumonic plague
Background: The transmission potential of primary pneumonic plague, caused by Yersinia pestis , is one of the key epidemiological determinants of a potential biological weapon, and requires clarification and time dependent interpretation. Method: This study estimated the reproduction number and its time dependent change through investigations of outbreaks in Mukden, China (1946), and Madagascar (1957). Reconstruction of an epidemic tree, which sh…
Modelling potential responses to severe acute respiratory syndrome in Japan
Background: There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. With the use of detailed epidemiological data from other countries, this article describes the possible reason for the SARS epidemic not appearing in Japan, and simulates the impact of different control strategies that can break the transmission cycle of SARS associated coronavirus. Method: Mathematical modelling is used for predicting the epidemiolo…
Transmission potential of primary pneumonic plague
Background: The transmission potential of primary pneumonic plague, caused by Yersinia pestis , is one of the key epidemiological determinants of a potential biological weapon, and requires clarification and time dependent interpretation. Method: This study estimated the reproduction number and its time dependent change through investigations of outbreaks in Mukden, China (1946), and Madagascar (1957). Reconstruction of an epidemic tree, which sh…
Modelling potential responses to severe acute respiratory syndrome in Japan
Background: There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. With the use of detailed epidemiological data from other countries, this article describes the possible reason for the SARS epidemic not appearing in Japan, and simulates the impact of different control strategies that can break the transmission cycle of SARS associated coronavirus. Method: Mathematical modelling is used for predicting the epidemiolo…
Modelling potential responses to severe acute respiratory syndrome in Japan
Background: There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. With the use of detailed epidemiological data from other countries, this article describes the possible reason for the SARS epidemic not appearing in Japan, and simulates the impact of different control strategies that can break the transmission cycle of SARS associated coronavirus. Method: Mathematical modelling is used for predicting the epidemiolo…
Transmission potential of primary pneumonic plague
Background: The transmission potential of primary pneumonic plague, caused by Yersinia pestis , is one of the key epidemiological determinants of a potential biological weapon, and requires clarification and time dependent interpretation. Method: This study estimated the reproduction number and its time dependent change through investigations of outbreaks in Mukden, China (1946), and Madagascar (1957). Reconstruction of an epidemic tree, which sh…
Correcting the Actual Reproduction Number
The basic reproduction number, R(0), a summary measure of the transmission potential of an infectious disease, is estimated from early epidemic growth rate, but a likelihood-based method for the estimation has yet to be developed. The present study corrects the concept of the actual reproduction number, offering a simple framework for estimating R(0) without assuming exponential growth of cases. The proposed method is applied to the HIV epidemic …
Vaccination and Clinical Severity
While contact tracing and case isolation are considered as the first choice of interventions against a smallpox bioterrorist event, their effectiveness under vaccination is questioned, because not only susceptibility of host and infectiousness of case but also the risk of severe clinical manifestations among cases is known to be reduced by vaccine-induced immunity, thereby potentially delaying the diagnosis and increasing mobility among vaccinate…
Environmental Drivers of Bacillus-Positive Blood Cultures in a Cancer Hospital, Sapporo, Japan
The Bacillus species is a well-documented causative pathogen of nosocomial bloodstream infection. The present study aimed to identify climatological variables that are associated with Bacillus -positive blood culture in Sapporo, Japan. All cases with Bacillus -positive blood cultures from January 2011 to December 2016 were retrospectively analysed. Climatological data from 2011 to 2016, including daily mean temperature and absolute humidity, were…
Assessing the Effectiveness and Cost-Benefit of Test-and-Vaccinate Policy for Supplementary Vaccination against Rubella with Limited Doses
Elevating herd immunity level against rubella is essential to prevent congenital rubella syndrome (CRS). Insufficient vaccination coverage left susceptible pockets among adults in Japan, and the outbreak of rubella from 2012 to 2013 resulted in 45 observed CRS cases. Given a limited stock of rubella-containing vaccine (RCV) available, the Japanese government recommended healthcare providers to prioritize vaccination to those confirmed with low le…
Modelling a Supplementary Vaccination Program of Rubella Using the 2012–2013 Epidemic Data in Japan
From 2012-2013, Japan experienced a major epidemic of rubella, involving a total of 12,614 rubella cases and 45 confirmed cases of congenital rubella syndrome (CRS). One of the contributory factors in this outbreak may have been that the majority of adult males remained unvaccinated. To plan for a supplementary immunization program (SIP) to elevate the herd immunity level, it is critical to determine the required amount of vaccine and identify th…
Interaction Among Influenza Viruses A/H1N1, A/H3N2, and B in Japan
Seasonal influenza epidemics occur each winter season in temperate zones, involving up to 650,000 deaths each year globally. A published study demonstrated that the circulation of one influenza virus type during early influenza season in the United States interferes with the activity of other influenza virus types. However, this finding has yet to be validated in other settings. In the present work, we investigated the interaction among seasonal …
Fluoroquinolone consumption and Escherichia coli resistance in Japan
Fluoroquinolone consumption and levofloxacin-resistant E. coli are potentially associated on a nationwide scale. The relationship between the two must be elucidated using additional studies with different epidemiological designs, so that any possible counter-measures, including alternative prescription, can be considered in the future
Ambulance Transport of Patients with Mild Conditions in Hokkaido, Japan
Understanding the epidemiological distributions of ambulance transport for patients with mild conditions according to age, disease, and geographic region could help in achieving optimal use of ambulance services. In the present study, we explored the descriptive epidemiology of ambulance transports in Hokkaido, the northernmost prefecture of Japan, identifying potential factors that determine the frequency of transports for mild diseases. Of the …
Quantifying the future risk of dengue under climate change in Japan
Background In metropolitan Tokyo in 2014, Japan experienced its first domestic dengue outbreak since 1945. The objective of the present study was to quantitatively assess the future risk of dengue in Japan using climate change scenarios in a high-resolution geospatial environment by building on a solid theory as a baseline in consideration of future adaptation strategies. Methods Using climate change scenarios of the Model for Interdisciplinary R…
Age-Dependent Risks of Covid-19 Putatively Caused by Variant Alpha in Japan
Background: Osaka, the third largest prefecture in Japan, experienced a rapid replacement of preexisting strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by variant alpha during March-April 2021. Assessing the burden of variant alpha on health centers and medical institutions is vital to anticipating the surge of patients. The present study aimed to estimate the age-dependent risks of coronavirus disease (COVID-19) putative…
Night-time population consistently explains the transmission dynamics of coronavirus disease 2019 in three megacities in Japan
Background: Mobility data are crucial for understanding the dynamics of coronavirus disease 2019 (COVID-19), but the consistency of the usefulness of these data over time has been questioned. The present study aimed to reveal the relationship between the transmissibility of COVID-19 in Tokyo, Osaka, and Aichi prefectures and the daily night-time population in metropolitan areas belonging to each prefecture. Methods: population in downtown areas e…
Possible adaptation measures for climate change in preventing heatstroke among older adults in Japan
Introduction: Heatstroke mortality is highest among older adults aged 65 years and older, and the risk is even doubled among those aged 75 years and older. The incidence of heatstroke is expected to increase in the future with elevated temperatures owing to climate change. In the context of a super-aged society, we examined possible adaptation measures in Japan that could prevent heatstroke among older people using an epidemiological survey combi…
A susceptible cluster in a religious camp allowed 2018–2019 measles outbreak in Japan
Objectives: We analyzed the 2018-2019 outbreak of measles in Japan, which started with a gathering at a religious youth camp in Mie, a prefecture located in the central part of Japan. Methods: A retrospective secondary analysis of cases from December 2018 to January 2019 was carried out. The index case was a Japanese man in his 20s living in Wakayama, a prefecture adjacent to Mie Prefecture. As part of his religious activities, he attended a yout…
Medicine (11 works) · Demography (10 works) · Biology (8 works) · Internal Medicine (8 works) · Environmental health (7 works) · Epidemiology (7 works) · Population (7 works) · COVID-19 epidemiological studies (6 works) · Outbreak (6 works) · Virology (6 works)