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Correcting the Actual Reproduction Number

A Simple Method to Estimate R0 from Early Epidemic Growth Data

Bibliographic Data

ID15498697
AuthorsHiroshi Nishiura (0000-0003-0941-8537, Utrecht University, corresponding author)
Year2010
Volume7
Issue1
Pages291-302
Publication date2010-01-21
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph7010291
PMID20195446
PMCIDPMC2819789
OpenAlexW2123665197
LanguageEN
Citations received3
References cited29

The basic reproduction number, R(0), a summary measure of the transmission potential of an infectious disease, is estimated from early epidemic growth rate, but a likelihood-based method for the estimation has yet to be developed. The present study corrects the concept of the actual reproduction number, offering a simple framework for estimating R(0) without assuming exponential growth of cases. The proposed method is applied to the HIV epidemic in European countries, yielding R(0) values ranging from 3.60 to 3.74, consistent with those based on the Euler-Lotka equation. The method also permits calculating the expected value of R(0) using a spreadsheet

Basic reproduction number · Biology · Econometrics · Economics · Epidemic model · Estimation · Exponential growth · Mathematical analysis · Maximum likelihood · Measure (data warehouse · Population · Reproduction · Simple (philosophy · Statistics · Computer Science · COVID-19 epidemiological studies · Demography · HIV/AIDS Impact and Responses · Mathematical and Theoretical Epidemiology and Ecology Models · Mathematics · Applied Mathematics · Ecology

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Citations per year1.5
Citation span2024 - 2024 (1)
Highly citedNo

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