Keren Middelkoop
Biographic Data
| ID | 6244168 |
|---|---|
| NAME | Keren Middelkoop |
| GIVEN NAMES | Keren |
| FAMILY NAME | Middelkoop |
| SIGNATURE | MIDDELKOOP K |
| AFFILIATIONS | Desmond Tutu HIV Foundation |
| ORCID | 0000-0001-9922-4263 |
| VERIFIED | Yes |
| TOTAL WORKS | 8 |
| TOTAL CITATIONS | 1 |
| WORKS AS AUTHOR | 8 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2006 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Within-country heterogeneity in patterns of social contact relevant for tuberculosis infection transmission, prevention, and care
Mycobacterium tuberculosis ( Mtb ) transmission is driven by variable social, environmental, and biological factors, including the number and duration of indoor contacts. Social contact data can provide information on potential transmission patterns, but is underutilised outside the field of mathematical modelling. We explore three contexts where contact data can provide valuable insights: 1) household contact tracing; 2) infection prevention and…
Airborne transmission risks of tuberculosis and Covid-19 in schools in South Africa, Switzerland, and Tanzania
The COVID-19 pandemic renewed interest in airborne transmission of respiratory infections, particularly in congregate indoor settings, such as schools. We modeled transmission risks of tuberculosis (caused by Mycobacterium tuberculosis , Mtb ) and COVID-19 (caused by SARS-CoV-2) in South African, Swiss and Tanzanian secondary schools. We estimated the risks of infection with the Wells-Riley equation, expressed as the median with 2.5% and 97.5% qu…
Diet, physical activity, and obesity among ART-experienced people with HIV in South Africa
The prevalence of non-communicable diseases (NCDs) is increasing in South Africa, in part due to poor nutrition, physical inactivity, and obesity. We characterized the habits and understanding of diet, exercise, and obesity among people with HIV (PWH) taking antiretroviral therapy (ART). We conducted a cross-sectional study of ART-experienced PWH attending an HIV community health center near Cape Town, South Africa. We included PWH currently pres…
Importance of ventilation and occupancy to Mycobacterium tuberculosis transmission rates in congregate settings
Public transport in particular may be promising targets for infection prevention and control interventions in this setting, both to reduce Mtb transmission, but also to reduce the transmission of other airborne pathogens such as measles and SARS-CoV-2
Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women
BACKGROUND: Safe and effective long-acting injectable agents for preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options for preventing HIV infection. METHODS: We conducted a randomized, double-blind, double-dummy, noninferiority trial to compare long-acting injectable cabotegravir (CAB-LA, an integrase strand-transfer inhibitor [INSTI]) at a dose of 600 mg, given intramuscularly every 8 …
Improving HIV testing amongst adolescents through an integrated Youth Centre rewards program
Changing patterns in HIV/Aids stigma and uptake of voluntary counselling and testing services
Voluntary counselling and HIV testing (VCT) has been associated with decreased human immunodeficiency virus (HIV) risk behaviour, but in South Africa, which has the largest HIV/acquired immune deficiency syndrome (AIDS) epidemic in the world, uptake of VCT remains low. HIV/AIDS-associated stigma has been identified as a barrier to HIV testing. This study explored changes in stigma, and VCT access in a peri-urban South African community with high …
Sexual risk factors associated with volunteering for HIV vaccine research in South Africa
There are few data on how the risk profiles of individuals who volunteer for HIV vaccine research compare to the general population from which participants are recruited. This study contrasts demographic and sexual risk behaviours among volunteers in an HIV vaccine preparedness cohort with data from a cross-sectional community survey conducted in the same peri-urban community during the same time period. For the HIV vaccine preparedness cohort, s…
Sexual risk factors associated with volunteering for HIV vaccine research in South Africa
There are few data on how the risk profiles of individuals who volunteer for HIV vaccine research compare to the general population from which participants are recruited. This study contrasts demographic and sexual risk behaviours among volunteers in an HIV vaccine preparedness cohort with data from a cross-sectional community survey conducted in the same peri-urban community during the same time period. For the HIV vaccine preparedness cohort, s…
Changing patterns in HIV/Aids stigma and uptake of voluntary counselling and testing services
Voluntary counselling and HIV testing (VCT) has been associated with decreased human immunodeficiency virus (HIV) risk behaviour, but in South Africa, which has the largest HIV/acquired immune deficiency syndrome (AIDS) epidemic in the world, uptake of VCT remains low. HIV/AIDS-associated stigma has been identified as a barrier to HIV testing. This study explored changes in stigma, and VCT access in a peri-urban South African community with high …
Improving HIV testing amongst adolescents through an integrated Youth Centre rewards program
Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women
BACKGROUND: Safe and effective long-acting injectable agents for preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options for preventing HIV infection. METHODS: We conducted a randomized, double-blind, double-dummy, noninferiority trial to compare long-acting injectable cabotegravir (CAB-LA, an integrase strand-transfer inhibitor [INSTI]) at a dose of 600 mg, given intramuscularly every 8 …
Importance of ventilation and occupancy to Mycobacterium tuberculosis transmission rates in congregate settings
Public transport in particular may be promising targets for infection prevention and control interventions in this setting, both to reduce Mtb transmission, but also to reduce the transmission of other airborne pathogens such as measles and SARS-CoV-2
Diet, physical activity, and obesity among ART-experienced people with HIV in South Africa
The prevalence of non-communicable diseases (NCDs) is increasing in South Africa, in part due to poor nutrition, physical inactivity, and obesity. We characterized the habits and understanding of diet, exercise, and obesity among people with HIV (PWH) taking antiretroviral therapy (ART). We conducted a cross-sectional study of ART-experienced PWH attending an HIV community health center near Cape Town, South Africa. We included PWH currently pres…
Airborne transmission risks of tuberculosis and Covid-19 in schools in South Africa, Switzerland, and Tanzania
The COVID-19 pandemic renewed interest in airborne transmission of respiratory infections, particularly in congregate indoor settings, such as schools. We modeled transmission risks of tuberculosis (caused by Mycobacterium tuberculosis , Mtb ) and COVID-19 (caused by SARS-CoV-2) in South African, Swiss and Tanzanian secondary schools. We estimated the risks of infection with the Wells-Riley equation, expressed as the median with 2.5% and 97.5% qu…
Within-country heterogeneity in patterns of social contact relevant for tuberculosis infection transmission, prevention, and care
Mycobacterium tuberculosis ( Mtb ) transmission is driven by variable social, environmental, and biological factors, including the number and duration of indoor contacts. Social contact data can provide information on potential transmission patterns, but is underutilised outside the field of mathematical modelling. We explore three contexts where contact data can provide valuable insights: 1) household contact tracing; 2) infection prevention and…
Medicine (8 works) · Environmental health (7 works) · HIV/AIDS Research and Interventions (5 works) · Adolescent Sexual and Reproductive Health (3 works) · COVID-19 epidemiological studies (3 works) · Demography (3 works) · Family medicine (3 works) · Gerontology (3 works) · Internal Medicine (3 works) · Population (3 works)