Sexual risk factors associated with volunteering for HIV vaccine research in South Africa
Bibliographic Data
| ID | 19439505 |
|---|---|
| Authors | J SMIT (a University of Stellenbosch , Cape Town , South Africa, corresponding author), Keren Middelkoop (0000-0001-9922-4263, University of Cape Town), Landon Myers (0000-0002-8106-7658, University of Cape Town), L Myer (b University of Cape Town , Cape Town , South Africa), Soraya Seedat (0000-0002-5118-786X, Stellenbosch University), Robin Wood (0000-0002-4276-7117, University of Cape Town), Dan J Stein (0000-0001-7218-7810, Stellenbosch University), Linda-Gail Bekker (0000-0002-0755-4386, University of Cape Town) |
| Year | 2006 |
| Volume | 18 |
| Issue | 6 |
| Pages | 569-573 |
| Publication date | 2006-08-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540120500274976 |
| PMID | 16831784 |
| OpenAlex | W2139779549 |
| Language | EN |
| Citations received | 1 |
| References cited | 14 |
There are few data on how the risk profiles of individuals who volunteer for HIV vaccine research compare to the general population from which participants are recruited. This study contrasts demographic and sexual risk behaviours among volunteers in an HIV vaccine preparedness cohort with data from a cross-sectional community survey conducted in the same peri-urban community during the same time period. For the HIV vaccine preparedness cohort, structured questionnaires were administered to 140 HIV-negative individuals aged between 16 and 40 years. A questionnaire with identical measures was self-administered in a cross-sectional community survey of 583 randomly selected individuals within the same age range. Compared to the local community sample, individuals who volunteered for the HIV vaccine preparedness cohort were younger (adjusted odds ratio = 0.48; 95% CI = 0.28-0.82), more likely to have had a sexually transmitted disease (adjusted odds ratio = 1.75; 95% CI = 1.03-2.99) and less likely to use condoms (adjusted odds ratio = 0.51; 95% CI = 0.3-0.86). Cohort participants were also more likely to perceive themselves and their partners to be at risk of HIV infection, though these associations did not persist in multivariate analysis. These findings suggest that volunteers for vaccine-related research may be at greater risk of HIV infection than the general population from which they are recruited
Cohort · Cohort study · Environmental health · Family medicine · HIV vaccine · Logistic regression · Multivariate analysis · Odds · Odds ratio · Population · Preparedness · Vaccine trial · Adolescent Sexual and Reproductive Health · Demography · HIV/AIDS Research and Interventions · Medicine · Vaccine Coverage and Hesitancy · Gerontology · Internal Medicine
| Citations per year | 0.06 |
|---|---|
| Citation span | 2009 - 2009 (1) |
| Highly cited | No |