Jan A Moynihan
Biographic Data
| ID | 6759648 |
|---|---|
| NAME | Jan A Moynihan |
| GIVEN NAMES | Jan A |
| FAMILY NAME | Moynihan |
| SIGNATURE | MOYNIHAN J A |
| AFFILIATIONS | University of Rochester Medicine |
| ORCID | 0000-0001-9513-5028 |
| VERIFIED | Yes |
| TOTAL WORKS | 8 |
| TOTAL CITATIONS | 4 |
| WORKS AS AUTHOR | 8 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1996 |
| LATEST PUBLICATION YEAR | 2017 |
| H-INDEX | 1 |
Social Relationships and Inflammatory Markers in the Midus Cohort
Greater social support may be related to lower IL-6 in older women. Further research is needed to understand observed associations of social support with higher CRP
Mindfulness-based stress reduction to enhance psychological functioning and improve inflammatory biomarkers in trauma-exposed women
This study examined the effects of a mindfulness-based stress reduction (MBSR) program on psychological functioning and inflammatory biomarkers in women with histories of interpersonal trauma. The 8-week MBSR program was conducted at a community-based health center and participants (N = 50) completed several measures of psychological functioning at study entry as well as 4 weeks, 8 weeks, and 12 weeks later. Inflammatory biomarkers were assayed f…
Psychiatric Symptoms and Proinflammatory Cytokines in Pregnancy
OBJECTIVE: Clinical studies suggest that psychiatric symptoms, particularly depression, anxiety, and trauma, may be associated with inflammation, as indexed by proinflammatory cytokines. Such a link may be especially significant in pregnancy and may shed additional light on the etiology of perinatal mood disorders. METHODS: We prospectively observed 145 women selected from a community obstetric clinic serving a primarily low-income, high-psychoso…
Moderating Effects of Moderate-Intensity Physical Activity in the Relationship Between Depressive Symptoms and Interleukin-6 in Primary Care Patients
OBJECTIVE: To determine whether the relationship between interleukin (IL)-6 and depressive symptoms is moderated by participation in moderate-intensity physical activity in a sample of primary care patients. Elevated inflammation has been associated with a number of poor health outcomes. Depressive symptoms may be related to higher levels of the inflammatory marker IL-6; however, previous findings are inconsistent, possibly due to unidentified mo…
History of Sudden Unexpected Loss Is Associated With Elevated Interleukin-6 and Decreased Insulin-Like Growth Factor-1 in Women in an Urban Primary Care Setting
OBJECTIVE: To investigate the hypothesis that a history of sudden unexpected loss including number of losses and type of loss (death due to unnatural versus natural causes) would be associated with the magnitude of dysregulation. The sudden unexpected death of a loved one confers risk of morbidity and mortality, perhaps due to dysregulation in the immune/inflammatory and endocrine systems. METHODS: Female primary care patients aged >or=40 years (…
Psychosocial Factors and the Response to Influenza Vaccination in Older Adults
Objective: We examined the influence of psychological state (depression, negative affect, perceived stress) and social support on pre- and post-vaccination response to influenza vaccine. Methods: Venous blood was drawn from 37 nursing home residents before and following injection of the trivalent influenza vaccine (comprised of the New Caledonia (NC), Hong Kong (HK), and Panama (Pan) strains of flu). The Geriatric Depression Scale, Perceived Stre…
Heart Rate, Neuroendocrine, and Immunological Reactivity in Response to an Acute Laboratory Stressor
OBJECTIVE: The primary objective of the present study was to identify neuroendocrine and immunological correlates of cardiovascular reactivity to an acute laboratory stressor. METHODS: Subjects were 56 healthy volunteers. Heart rate and blood pressure were assessed at regular intervals during a 30-minute adaptation period and a 6-minute videotaped speech task. Blood was drawn before and after the task and was assayed for natural killer cell activ…
Psychoneuroimmunology
OBJECTIVE: Psychoneuroimmunology, which investigates the bidirectional communication between the central nervous system and the immune system, has been greatly advanced by the use of animal models. The objective of this paper is to describe animal models of disease that can or might be utilized to elucidate neural-immune interactions that alter pathogenesis. METHODS: This paper reviews animal studies that have demonstrated a link among the brain,…
Social Relationships and Inflammatory Markers in the Midus Cohort
Greater social support may be related to lower IL-6 in older women. Further research is needed to understand observed associations of social support with higher CRP
Psychoneuroimmunology
OBJECTIVE: Psychoneuroimmunology, which investigates the bidirectional communication between the central nervous system and the immune system, has been greatly advanced by the use of animal models. The objective of this paper is to describe animal models of disease that can or might be utilized to elucidate neural-immune interactions that alter pathogenesis. METHODS: This paper reviews animal studies that have demonstrated a link among the brain,…
Heart Rate, Neuroendocrine, and Immunological Reactivity in Response to an Acute Laboratory Stressor
OBJECTIVE: The primary objective of the present study was to identify neuroendocrine and immunological correlates of cardiovascular reactivity to an acute laboratory stressor. METHODS: Subjects were 56 healthy volunteers. Heart rate and blood pressure were assessed at regular intervals during a 30-minute adaptation period and a 6-minute videotaped speech task. Blood was drawn before and after the task and was assayed for natural killer cell activ…
Psychosocial Factors and the Response to Influenza Vaccination in Older Adults
Objective: We examined the influence of psychological state (depression, negative affect, perceived stress) and social support on pre- and post-vaccination response to influenza vaccine. Methods: Venous blood was drawn from 37 nursing home residents before and following injection of the trivalent influenza vaccine (comprised of the New Caledonia (NC), Hong Kong (HK), and Panama (Pan) strains of flu). The Geriatric Depression Scale, Perceived Stre…
History of Sudden Unexpected Loss Is Associated With Elevated Interleukin-6 and Decreased Insulin-Like Growth Factor-1 in Women in an Urban Primary Care Setting
OBJECTIVE: To investigate the hypothesis that a history of sudden unexpected loss including number of losses and type of loss (death due to unnatural versus natural causes) would be associated with the magnitude of dysregulation. The sudden unexpected death of a loved one confers risk of morbidity and mortality, perhaps due to dysregulation in the immune/inflammatory and endocrine systems. METHODS: Female primary care patients aged >or=40 years (…
Psychiatric Symptoms and Proinflammatory Cytokines in Pregnancy
OBJECTIVE: Clinical studies suggest that psychiatric symptoms, particularly depression, anxiety, and trauma, may be associated with inflammation, as indexed by proinflammatory cytokines. Such a link may be especially significant in pregnancy and may shed additional light on the etiology of perinatal mood disorders. METHODS: We prospectively observed 145 women selected from a community obstetric clinic serving a primarily low-income, high-psychoso…
Moderating Effects of Moderate-Intensity Physical Activity in the Relationship Between Depressive Symptoms and Interleukin-6 in Primary Care Patients
OBJECTIVE: To determine whether the relationship between interleukin (IL)-6 and depressive symptoms is moderated by participation in moderate-intensity physical activity in a sample of primary care patients. Elevated inflammation has been associated with a number of poor health outcomes. Depressive symptoms may be related to higher levels of the inflammatory marker IL-6; however, previous findings are inconsistent, possibly due to unidentified mo…
Mindfulness-based stress reduction to enhance psychological functioning and improve inflammatory biomarkers in trauma-exposed women
This study examined the effects of a mindfulness-based stress reduction (MBSR) program on psychological functioning and inflammatory biomarkers in women with histories of interpersonal trauma. The 8-week MBSR program was conducted at a community-based health center and participants (N = 50) completed several measures of psychological functioning at study entry as well as 4 weeks, 8 weeks, and 12 weeks later. Inflammatory biomarkers were assayed f…
Social Relationships and Inflammatory Markers in the Midus Cohort
Greater social support may be related to lower IL-6 in older women. Further research is needed to understand observed associations of social support with higher CRP
Medicine (8 works) · Psychology (6 works) · Internal Medicine (5 works) · Clinical Psychology (4 works) · Immunology (4 works) · Immunology (4 works) · Internal Medicine (4 works) · Psychiatry (4 works) · Stress Responses and Cortisol (4 works) · Anxiety (3 works)