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Eelko Hak

Biographic Data

ID6764082
NAMEEelko Hak
GIVEN NAMESEelko
FAMILY NAMEHak
SIGNATUREHAK E
AFFILIATIONSUniversity of Groningen
ORCID0000-0003-0849-7210
VERIFIEDYes
TOTAL WORKS13
TOTAL CITATIONS2
WORKS AS AUTHOR13
WORKS AS EDITOR0
FIRST PUBLICATION YEAR1998
LATEST PUBLICATION YEAR2025
H-INDEX1
  • Development of a prediction rule for incomplete vaccination among children in Indonesia

    Open Access•Sofa D Alfian, Rizky Abdulah et al.•ARTICLE•BMC Public Health•2025

    This novel, easy-to-use prediction rule could be a useful tool to complement current strategies and further encourage tailored vaccine uptake interventions, particularly to parents with a high chance of incompletely vaccinated children in Indonesia

  • Metabolic syndrome in adults with autistic traits

    Open Access•Eva B Warreman, L A Nooteboom et al.•ARTICLE•Frontiers in Psychiatry•2023

    These findings underline the relevance of adequate cardiovascular prevention in adults with higher levels of autistic traits. Future research could gain more insight into the relationship between cardiovascular risk and autistic traits in females, and into tailored cardiovascular prevention

  • Measles outbreak in complex emergency

    Open Access•Anne Eudes Jean Baptiste, John Wagai et al.•ARTICLE•BMC Public Health•2021

    The experience in Borno demonstrates that adequate VE can be obtained in conflict-affected areas. In complex emergencies affected by measles outbreaks, health authorities may consider integration with other health strategies and the engagement of security personnel as part of the ORI activities

  • Barriers and strategies to successful tuberculosis treatment in a high-burden tuberculosis setting

    Open Access•Ivan Surya Pradipta, Lusiana R Idrus et al.•ARTICLE•BMC Public Health•2021

    The main treatment barriers can be considered to strengthen patient-centred care for TB patients in Indonesia. A multi-component approach including TB patients, healthcare providers, broad community and policy makers is required to improve TB treatment success

  • Association Between BDNF Gene Variant Rs6265 and the Severity of Depression in Antidepressant Treatment-Free Depressed Patients

    Open Access•Innokentiy S Losenkov, Nathaniël J V Mulder et al.•ARTICLE•Frontiers in Psychiatry•2020

    We observed a significant association between BDNF gene variant rs6265 and the severity of depression in newly admitted, antidepressant treatment-free, depressed patients. Actual PRL and BDNF levels were not elevated sufficiently in depressed patients to reach statistical significance and were not associated with the studied genotypes

  • The effect of adherence to statin therapy on cardiovascular mortality

    Open Access•Maarten J Bijlsma, Stijn Vansteelandt et al.•ARTICLE•BMC Public Health•2016

    Falsification end-points helped detect overadjustment bias or bias due to competing risks, and thereby proved to be a useful technique in such a complex setting

  • Prevalence and predictors of over-the-counter medication use among pregnant women

    Open Access•Gwenny MPJ Verstappen, Elise J Smolders et al.•ARTICLE•BMC Public Health•2013

    It is possible to indicate women at risk for OTC-medication use during pregnancy, using five maternal characteristics that independently contribute to the prediction model. The predictors are easy to estimate and the model is easy to implement in daily practice

  • Perceived Discomfort Levels in Healthy Children Participating in Vaccine Research

    Open Access•Anna E Westra, Elske J M van Gils et al.•ARTICLE•Journal of Empirical Research on…•2013

    When assessing the risks of a research protocol, review boards need to consider not only the possible harms but also the expected discomfort levels caused by the various study procedures. However, data on how children experience various study procedures are scarce. This study assessed perceived discomfort levels in 671 healthy children aged 0-2 years under-going vaccinations, venipunctures, and nasopharyngeal swab taking. In half of the study par…

  • Comparatively low attendance during Human Papillomavirus catch-up vaccination among teenage girls in the Netherlands

    Open Access•Giedrė Gefenaitė, Marieke Smit et al.•ARTICLE•BMC Public Health•2012

    This study revealed several determinants for HPV vaccination uptake after implementation of the HPV vaccine for adolescent girls. These determinants should be taken into consideration in order to successfully implement HPV vaccination into National Immunization Programs

  • Contributing factors to influenza vaccine uptake in general hospitals

    Open Access•Josien Riphagen‐Dalhuisen, Josien Riphagen-Dalhuisen et al.•ARTICLE•BMC Public Health•2012

    Agreement with positive statements about management factors with regard to influenza vaccination were not associated with the uptake. More economic investments were related with a higher vaccine uptake; the reasons for this should be explored further

  • Cost-effectiveness of rotavirus vaccination in the Netherlands; the results of a consensus model

    Open Access•Mark H Rozenbaum, Marie‐Josée J Mangen et al.•ARTICLE•BMC Public Health•2011

    Our economic analysis indicates that inclusion of rotavirus vaccination in the Dutch National Immunization Program might be cost-effective depending on the cost of the vaccine and the impact of rotavirus gastroenteritis on children's quality of life

  • Confounding by indication in non-experimental evaluation of vaccine effectiveness

    Eelko Hak, Th J M Verheij et al.•ARTICLE•Journal of Epidemiology and…•2002•References: 29

    Randomised allocation of vaccine or placebo is the preferred method to assess the effects of the vaccine on clinical outcomes relevant to the individual patient. In the absence of phase 3 trials using clinical end points, notably post-influenza complications, alternative non-experimental designs to evaluate vaccine effects or safety are often used. The application of these designs may, however, lead to invalid estimates of vaccine effectiveness o…

  • Is immunising all patients with chronic lung disease in the community against influenza cost effective? Evidence from a general practice based clinical prospective cohort study in Utrecht, The Netherl…

    Eelko Hak, Gerrit A van Essen et al.•ARTICLE•Journal of Epidemiology and…•1998•Cited by: 2•References: 23

    STUDY OBJECTIVE: There is little information on the potential benefit of immunising all patients with chronic lung disease in the community against influenza. The clinical effectiveness and economic benefit was established of the influenza vaccination programme in a general practice based cohort of adult patients with chronic lung disease followed up during the 1995/96 influenza A epidemic. DESIGN: A prospective cohort study from October 1995 to …

  • Is immunising all patients with chronic lung disease in the community against influenza cost effective? Evidence from a general practice based clinical prospective cohort study in Utrecht, The Netherl…

    Eelko Hak, Gerrit A van Essen et al.•ARTICLE•Journal of Epidemiology and…•1998•Cited by: 2•References: 23

    STUDY OBJECTIVE: There is little information on the potential benefit of immunising all patients with chronic lung disease in the community against influenza. The clinical effectiveness and economic benefit was established of the influenza vaccination programme in a general practice based cohort of adult patients with chronic lung disease followed up during the 1995/96 influenza A epidemic. DESIGN: A prospective cohort study from October 1995 to …

  • Is immunising all patients with chronic lung disease in the community against influenza cost effective? Evidence from a general practice based clinical prospective cohort study in Utrecht, The Netherl…

    Eelko Hak, Gerrit A van Essen et al.•ARTICLE•Journal of Epidemiology and…•1998•Cited by: 2•References: 23

    STUDY OBJECTIVE: There is little information on the potential benefit of immunising all patients with chronic lung disease in the community against influenza. The clinical effectiveness and economic benefit was established of the influenza vaccination programme in a general practice based cohort of adult patients with chronic lung disease followed up during the 1995/96 influenza A epidemic. DESIGN: A prospective cohort study from October 1995 to …

  • Confounding by indication in non-experimental evaluation of vaccine effectiveness

    Eelko Hak, Th J M Verheij et al.•ARTICLE•Journal of Epidemiology and…•2002•References: 29

    Randomised allocation of vaccine or placebo is the preferred method to assess the effects of the vaccine on clinical outcomes relevant to the individual patient. In the absence of phase 3 trials using clinical end points, notably post-influenza complications, alternative non-experimental designs to evaluate vaccine effects or safety are often used. The application of these designs may, however, lead to invalid estimates of vaccine effectiveness o…

  • Cost-effectiveness of rotavirus vaccination in the Netherlands; the results of a consensus model

    Open Access•Mark H Rozenbaum, Marie‐Josée J Mangen et al.•ARTICLE•BMC Public Health•2011

    Our economic analysis indicates that inclusion of rotavirus vaccination in the Dutch National Immunization Program might be cost-effective depending on the cost of the vaccine and the impact of rotavirus gastroenteritis on children's quality of life

  • Comparatively low attendance during Human Papillomavirus catch-up vaccination among teenage girls in the Netherlands

    Open Access•Giedrė Gefenaitė, Marieke Smit et al.•ARTICLE•BMC Public Health•2012

    This study revealed several determinants for HPV vaccination uptake after implementation of the HPV vaccine for adolescent girls. These determinants should be taken into consideration in order to successfully implement HPV vaccination into National Immunization Programs

  • Contributing factors to influenza vaccine uptake in general hospitals

    Open Access•Josien Riphagen‐Dalhuisen, Josien Riphagen-Dalhuisen et al.•ARTICLE•BMC Public Health•2012

    Agreement with positive statements about management factors with regard to influenza vaccination were not associated with the uptake. More economic investments were related with a higher vaccine uptake; the reasons for this should be explored further

  • Prevalence and predictors of over-the-counter medication use among pregnant women

    Open Access•Gwenny MPJ Verstappen, Elise J Smolders et al.•ARTICLE•BMC Public Health•2013

    It is possible to indicate women at risk for OTC-medication use during pregnancy, using five maternal characteristics that independently contribute to the prediction model. The predictors are easy to estimate and the model is easy to implement in daily practice

  • Perceived Discomfort Levels in Healthy Children Participating in Vaccine Research

    Open Access•Anna E Westra, Elske J M van Gils et al.•ARTICLE•Journal of Empirical Research on…•2013

    When assessing the risks of a research protocol, review boards need to consider not only the possible harms but also the expected discomfort levels caused by the various study procedures. However, data on how children experience various study procedures are scarce. This study assessed perceived discomfort levels in 671 healthy children aged 0-2 years under-going vaccinations, venipunctures, and nasopharyngeal swab taking. In half of the study par…

  • The effect of adherence to statin therapy on cardiovascular mortality

    Open Access•Maarten J Bijlsma, Stijn Vansteelandt et al.•ARTICLE•BMC Public Health•2016

    Falsification end-points helped detect overadjustment bias or bias due to competing risks, and thereby proved to be a useful technique in such a complex setting

  • Association Between BDNF Gene Variant Rs6265 and the Severity of Depression in Antidepressant Treatment-Free Depressed Patients

    Open Access•Innokentiy S Losenkov, Nathaniël J V Mulder et al.•ARTICLE•Frontiers in Psychiatry•2020

    We observed a significant association between BDNF gene variant rs6265 and the severity of depression in newly admitted, antidepressant treatment-free, depressed patients. Actual PRL and BDNF levels were not elevated sufficiently in depressed patients to reach statistical significance and were not associated with the studied genotypes

  • Measles outbreak in complex emergency

    Open Access•Anne Eudes Jean Baptiste, John Wagai et al.•ARTICLE•BMC Public Health•2021

    The experience in Borno demonstrates that adequate VE can be obtained in conflict-affected areas. In complex emergencies affected by measles outbreaks, health authorities may consider integration with other health strategies and the engagement of security personnel as part of the ORI activities

  • Barriers and strategies to successful tuberculosis treatment in a high-burden tuberculosis setting

    Open Access•Ivan Surya Pradipta, Lusiana R Idrus et al.•ARTICLE•BMC Public Health•2021

    The main treatment barriers can be considered to strengthen patient-centred care for TB patients in Indonesia. A multi-component approach including TB patients, healthcare providers, broad community and policy makers is required to improve TB treatment success

  • Metabolic syndrome in adults with autistic traits

    Open Access•Eva B Warreman, L A Nooteboom et al.•ARTICLE•Frontiers in Psychiatry•2023

    These findings underline the relevance of adequate cardiovascular prevention in adults with higher levels of autistic traits. Future research could gain more insight into the relationship between cardiovascular risk and autistic traits in females, and into tailored cardiovascular prevention

  • Development of a prediction rule for incomplete vaccination among children in Indonesia

    Open Access•Sofa D Alfian, Rizky Abdulah et al.•ARTICLE•BMC Public Health•2025

    This novel, easy-to-use prediction rule could be a useful tool to complement current strategies and further encourage tailored vaccine uptake interventions, particularly to parents with a high chance of incompletely vaccinated children in Indonesia

Medicine (13 works) · Internal Medicine (9 works) · Immunology (7 works) · Vaccination (7 works) · Biostatistics (6 works) · Environmental health (5 works) · Influenza Virus Research Studies (5 works) · Public health (5 works) · Vaccine Coverage and Hesitancy (5 works) · Family medicine (4 works)

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