Association Between BDNF Gene Variant Rs6265 and the Severity of Depression in Antidepressant Treatment-Free Depressed Patients

Bibliographic Data

ID15526168
AuthorsInnokentiy S Losenkov (0000-0001-7458-2179, Tomsk National Research Medical Center), Nathaniël J V Mulder (University of Groningen), Л А Левчук (0000-0003-1982-8492, Tomsk National Research Medical Center), Lyudmila A Levchuk, Natalya M Vyalova (0000-0001-6464-6474, Tomsk National Research Medical Center), A J M Loonen (0000-0003-4942-6195, University of Groningen, corresponding author), Fokko J Bosker (University of Groningen), Г Г Симуткин (0000-0002-9813-3789, Tomsk National Research Medical Center), German G Simutkin, Anastasiia S Boiko (0000-0002-2955-9057, Tomsk National Research Medical Center), Н А Бохан (0000-0002-1052-855X, Siberian State Medical University), Nikolay A Bokhan, Bob Wilffert (0000-0002-8759-5697, University Medical Center Groningen), Eelko Hak (0000-0003-0849-7210, University of Groningen), Amand F Schmidt (0000-0003-1327-0424, University of Groningen), Svetlana А Ivanova (0000-0001-7078-323X, Tomsk National Research Medical Center), Svetlana A Ivanova
Year2020
Volume11
Pages38-38
Publication date2020-02-12
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2020.00038
PMID32116853
OpenAlexW3006523294
LanguageEN
Citations received2
References cited31

We observed a significant association between BDNF gene variant rs6265 and the severity of depression in newly admitted, antidepressant treatment-free, depressed patients. Actual PRL and BDNF levels were not elevated sufficiently in depressed patients to reach statistical significance and were not associated with the studied genotypes

Antidepressant · Anxiety · Brain-derived neurotrophic factor · Depression (economics · Neurotrophic factors · Psychiatry · rs6265 · Autism Spectrum Disorder Research · Clinical Psychology · Medicine · Nerve injury and regeneration · Nuclear Receptors and Signaling · Psychology · Internal Medicine · Oncology

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