Issaka Sagara
Biographic Data
| ID | 7003701 |
|---|---|
| NAME | Issaka Sagara |
| GIVEN NAMES | Issaka |
| FAMILY NAME | Sagara |
| SIGNATURE | SAGARA I |
| AFFILIATIONS | Inserm |
| ORCID | 0000-0002-8555-9983 |
| VERIFIED | Yes |
| TOTAL WORKS | 15 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 15 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2006 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context
BACKGROUND: The R21/Matrix-M malaria vaccine has been shown to provide high protective efficacy against malaria in a phase III trial, and has been recommended for use by WHO. The vaccine will soon be deployed at scale in sub-Saharan Africa. This study aimed to understand the caregiver and community acceptability of the R21/Matrix-M vaccine alongside existing malaria prevention interventions, according to the communities of participants in the sea…
Distribution and determinants of Covid-19 seroprevalence in a hard-to-access health district in Mali
In November 2023, three years after the onset of the pandemic, Mali officially recorded 33,160 confirmed COVID-19 cases and 743 related deaths. Tombouctou health district, following Bamako, the capital city, emerged as the second major hotspot with over 532 confirmed cases. However, these figures likely underestimate the true scale of the epidemic due to limited healthcare access and diagnostic capacity. This study aimed to describe the early tra…
Geo-epidemiological risk stratification to select malaria interventions, case of Mali
Malaria is a public health threat in Mali, with high morbidity (37%) and mortality (25%) rates. Malaria risk stratification is needed to identify different risk transmission and select interventions, especially in resource-limited contexts. For the new National Strategic Plan, we updated stratification with World Health Organization (WHO) recommendation and presents the selection of interventions based on stratification. Data collection covered a…
Impact of seasonal malaria chemoprevention timing on clinical malaria incidence dynamics in the Kedougou region, Senegal
Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine is recommended by the World Health Organization since 2012 for clinical malaria prevention in children in the Sahelian region of Africa. In Senegal, SMC implementation began in 2013 and is given to children under 10 years old. This study aimed to describe clinical malaria incidence in the general population during routine SMC implementation and to analyse how SM…
Consommation de substances psychoactives chez les élèves de 15-25 ans à Gao
Les jeunes constituent un groupe particulièrement vulnérable à l’usage de substances psychoactives. Il n’existe aucun rapport sur les facteurs associés à la consommation de substances psychoactives dans cette population spécifique au Mali. L’objectif de cette étude était de déterminer la prévalence de la consommation de substances psychoactives légales ou illégales et d’identifier ses facteurs associés chez les jeunes scolaires de Gao au Mali. No…
Delivery strategies for malaria vaccination in areas with seasonal malaria transmission
Background Seasonal vaccination with the RTS,S/AS01 E malaria vaccine given alongside seasonal malaria chemoprevention (SMC) substantially reduces malaria in young children. The WHO has recommended the use of RTS,S/AS01 E , including seasonal vaccination, in areas with seasonal malaria transmission. This study aimed to identify potential strategies to deliver RTS,S/AS01 E , and assess the considerations and recommendations for delivery of seasona…
Adapting malaria clinical trials infrastructure to implement Covid-19 epidemiology studies
OPINION article Front. Public Health, 26 July 2022Sec. Infectious Diseases – Surveillance, Prevention and Treatment https://doi.org/10.3389/fpubh.2022.959678
Spatio-Temporal Variability of Malaria Incidence in the Health District of Kati, Mali, 2015–2019
Our study confirmed the important variability of malaria incidence and found malaria transmission to be associated with several meteorological and environmental factors in the Kati district. The persistence of malaria during the dry season and the spatio-temporal variability of malaria hotspots reinforce the need for innovative and targeted strategies
Evolution of Malaria Incidence in Five Health Districts, in the Context of the Scaling up of Seasonal Malaria Chemoprevention, 2016 to 2018, in Mali
A decrease in the incidence of malaria was observed after the SMC rounds. SMC should be applied at optimal periods
Geo-Epidemiology of Malaria at the Health Area Level, Dire Health District, Mali, 2013–2017
Background : According to the World Health Organization, there were more than 228 million cases of malaria globally in 2018, with 93% of cases occurring in Africa; in Mali, a 13% increase in the number of cases was observed between 2015 and 2018; this study aimed to evaluate the impact of meteorological and environmental factors on the geo-epidemiology of malaria in the health district of Dire, Mali. Methods : Meteorological and environmental var…
Spatio-Temporal Dynamic of Malaria Incidence
Malaria transmission largely depends on environmental, climatic, and hydrological conditions. In Mali, malaria epidemiological patterns are nested within three ecological zones. This study aimed at assessing the relationship between those conditions and the incidence of malaria in Dangassa and Koila, Mali. Malaria data was collected through passive case detection at community health facilities of each study site from June 2015 to January 2017. Cl…
Predicting Malaria Transmission Dynamics in Dangassa, Mali
Mali aims to reach the pre-elimination stage of malaria by the next decade. This study used functional regression models to predict the incidence of malaria as a function of past meteorological patterns to better prevent and to act proactively against impending malaria outbreaks. All data were collected over a five-year period (2012-2017) from 1400 persons who sought treatment at Dangassa's community health center. Rainfall, temperature, humidity…
Two-Year Scale-Up of Seasonal Malaria Chemoprevention Reduced Malaria Morbidity among Children in the Health District of Koutiala, Mali
SMC significantly reduced frequency of malaria infection, clinical malaria and anemia two years after SMC scale-up in Koutiala
Increase in EPI vaccines coverage after implementation of intermittent preventive treatment of malaria in infant with Sulfadoxine -pyrimethamine in the district of Kolokani, Mali
This study shows that high coverage of the IPTi can be obtained when the strategy is implemented using routine health services and implementation results in a significant increase in coverage of EPI vaccines in the district of Kolokani, Mali
Space-time clustering of childhood malaria at the household level
This study showed that, although infection proportions tended to decrease, high-risk zones persisted in the village particularly near temporal backwaters. Analysis of this heterogeneity at the household scale by GIS methods lead to target preventive actions more accurately on the high-risk zones identified. This mapping of malaria risk makes it possible to orient control programs, treating the high-risk zones identified as a matter of priority, a…
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Space-time clustering of childhood malaria at the household level
This study showed that, although infection proportions tended to decrease, high-risk zones persisted in the village particularly near temporal backwaters. Analysis of this heterogeneity at the household scale by GIS methods lead to target preventive actions more accurately on the high-risk zones identified. This mapping of malaria risk makes it possible to orient control programs, treating the high-risk zones identified as a matter of priority, a…
Increase in EPI vaccines coverage after implementation of intermittent preventive treatment of malaria in infant with Sulfadoxine -pyrimethamine in the district of Kolokani, Mali
This study shows that high coverage of the IPTi can be obtained when the strategy is implemented using routine health services and implementation results in a significant increase in coverage of EPI vaccines in the district of Kolokani, Mali
Geo-Epidemiology of Malaria at the Health Area Level, Dire Health District, Mali, 2013–2017
Background : According to the World Health Organization, there were more than 228 million cases of malaria globally in 2018, with 93% of cases occurring in Africa; in Mali, a 13% increase in the number of cases was observed between 2015 and 2018; this study aimed to evaluate the impact of meteorological and environmental factors on the geo-epidemiology of malaria in the health district of Dire, Mali. Methods : Meteorological and environmental var…
Spatio-Temporal Dynamic of Malaria Incidence
Malaria transmission largely depends on environmental, climatic, and hydrological conditions. In Mali, malaria epidemiological patterns are nested within three ecological zones. This study aimed at assessing the relationship between those conditions and the incidence of malaria in Dangassa and Koila, Mali. Malaria data was collected through passive case detection at community health facilities of each study site from June 2015 to January 2017. Cl…
Predicting Malaria Transmission Dynamics in Dangassa, Mali
Mali aims to reach the pre-elimination stage of malaria by the next decade. This study used functional regression models to predict the incidence of malaria as a function of past meteorological patterns to better prevent and to act proactively against impending malaria outbreaks. All data were collected over a five-year period (2012-2017) from 1400 persons who sought treatment at Dangassa's community health center. Rainfall, temperature, humidity…
Two-Year Scale-Up of Seasonal Malaria Chemoprevention Reduced Malaria Morbidity among Children in the Health District of Koutiala, Mali
SMC significantly reduced frequency of malaria infection, clinical malaria and anemia two years after SMC scale-up in Koutiala
Evolution of Malaria Incidence in Five Health Districts, in the Context of the Scaling up of Seasonal Malaria Chemoprevention, 2016 to 2018, in Mali
A decrease in the incidence of malaria was observed after the SMC rounds. SMC should be applied at optimal periods
Adapting malaria clinical trials infrastructure to implement Covid-19 epidemiology studies
OPINION article Front. Public Health, 26 July 2022Sec. Infectious Diseases – Surveillance, Prevention and Treatment https://doi.org/10.3389/fpubh.2022.959678
Spatio-Temporal Variability of Malaria Incidence in the Health District of Kati, Mali, 2015–2019
Our study confirmed the important variability of malaria incidence and found malaria transmission to be associated with several meteorological and environmental factors in the Kati district. The persistence of malaria during the dry season and the spatio-temporal variability of malaria hotspots reinforce the need for innovative and targeted strategies
Delivery strategies for malaria vaccination in areas with seasonal malaria transmission
Background Seasonal vaccination with the RTS,S/AS01 E malaria vaccine given alongside seasonal malaria chemoprevention (SMC) substantially reduces malaria in young children. The WHO has recommended the use of RTS,S/AS01 E , including seasonal vaccination, in areas with seasonal malaria transmission. This study aimed to identify potential strategies to deliver RTS,S/AS01 E , and assess the considerations and recommendations for delivery of seasona…
Consommation de substances psychoactives chez les élèves de 15-25 ans à Gao
Les jeunes constituent un groupe particulièrement vulnérable à l’usage de substances psychoactives. Il n’existe aucun rapport sur les facteurs associés à la consommation de substances psychoactives dans cette population spécifique au Mali. L’objectif de cette étude était de déterminer la prévalence de la consommation de substances psychoactives légales ou illégales et d’identifier ses facteurs associés chez les jeunes scolaires de Gao au Mali. No…
Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context
BACKGROUND: The R21/Matrix-M malaria vaccine has been shown to provide high protective efficacy against malaria in a phase III trial, and has been recommended for use by WHO. The vaccine will soon be deployed at scale in sub-Saharan Africa. This study aimed to understand the caregiver and community acceptability of the R21/Matrix-M vaccine alongside existing malaria prevention interventions, according to the communities of participants in the sea…
Distribution and determinants of Covid-19 seroprevalence in a hard-to-access health district in Mali
In November 2023, three years after the onset of the pandemic, Mali officially recorded 33,160 confirmed COVID-19 cases and 743 related deaths. Tombouctou health district, following Bamako, the capital city, emerged as the second major hotspot with over 532 confirmed cases. However, these figures likely underestimate the true scale of the epidemic due to limited healthcare access and diagnostic capacity. This study aimed to describe the early tra…
Geo-epidemiological risk stratification to select malaria interventions, case of Mali
Malaria is a public health threat in Mali, with high morbidity (37%) and mortality (25%) rates. Malaria risk stratification is needed to identify different risk transmission and select interventions, especially in resource-limited contexts. For the new National Strategic Plan, we updated stratification with World Health Organization (WHO) recommendation and presents the selection of interventions based on stratification. Data collection covered a…
Impact of seasonal malaria chemoprevention timing on clinical malaria incidence dynamics in the Kedougou region, Senegal
Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine is recommended by the World Health Organization since 2012 for clinical malaria prevention in children in the Sahelian region of Africa. In Senegal, SMC implementation began in 2013 and is given to children under 10 years old. This study aimed to describe clinical malaria incidence in the general population during routine SMC implementation and to analyse how SM…
Malaria (13 works) · Malaria Research and Control (12 works) · Medicine (12 works) · Environmental health (11 works) · Mosquito-borne diseases and control (10 works) · Geography (9 works) · Immunology (9 works) · COVID-19 epidemiological studies (6 works) · Demography (4 works) · Mathematics (4 works)