Daihai He
Biographic Data
| ID | 7035249 |
|---|---|
| NAME | Daihai He |
| GIVEN NAMES | Daihai |
| FAMILY NAME | He |
| SIGNATURE | HE D |
| AFFILIATIONS | Hong Kong Polytechnic University |
| ORCID | 0000-0003-3253-654X |
| VERIFIED | Yes |
| TOTAL WORKS | 13 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 13 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2019 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 0 |
The immune evasion ability of Delta variant is comparable to that of Beta variant in South Africa
We conclude that the immune evasion ability of Beta variant is not stronger than Delta variant, and indeed, the immune evasion abilities of both variants are weak in South Africa
Modelling Covid-19 vaccine breakthrough infections in highly vaccinated Israel—The effects of waning immunity and third vaccination dose
In August 2021, a major wave of the SARS-CoV-2 Delta variant erupted in the highly vaccinated population of Israel. The transmission advantage of the Delta variant enabled it to replace the Alpha variant in approximately two months. The outbreak led to an unexpectedly large proportion of breakthrough infections (BTI)–a phenomenon that received worldwide attention. Most of the Israeli population, especially those aged 60+, received their second do…
Multiple Covid-19 Waves and Vaccination Effectiveness in the United States
(1) Background: The coronavirus 2019 (COVID-19) pandemic has caused multiple waves of cases and deaths in the United States (US). The wild strain, the Alpha variant (B.1.1.7) and the Delta variant (B.1.617.2) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were the principal culprits behind these waves. To mitigate the pandemic, the vaccination campaign was started in January 2021. While the vaccine efficacy is less than 1, breakt…
Modelling of Waning of Immunity and Reinfection Induced Antibody Boosting of Sars-CoV-2 in Manaus, Brazil
It was reported that the Brazilian city, Manaus, likely exceeded the herd immunity threshold (presumably 60-70%) in November 2020 after the first wave of COVID-19, based on the serological data of a routine blood donor. However, a second wave started in November 2020, when an even higher magnitude of deaths hit the city. The arrival of the second wave coincided with the emergence of the Gamma (P.1) variant of SARS-CoV-2, with higher transmissibil…
Reinfection or Reactivation of Severe Acute Respiratory Syndrome Coronavirus 2
As the pandemic continues, individuals with re-detectable positive (RP) SARS-CoV-2 viral RNA among recovered COVID-19 patients have raised public health concerns. It is imperative to investigate whether the cases with re-detectable positive (RP) SARS-CoV-2 might cause severe infection to the vulnerable population. In this work, we conducted a systematic review of recent literature to investigate reactivation and reinfection among the discharged C…
The Disease Severity and Clinical Outcomes of the Sars-CoV-2 Variants of Concern
With the continuation of the pandemic, many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of increasing the transmissibility of the virus, severity of the infected individuals, and the ability to escape the antibody produced by the vaccines, the four SARS-CoV-2 variants of Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2) have attracted the most wid…
Estimating the Instantaneous Asymptomatic Proportion With a Simple Approach
Background: The asymptomatic proportion is a critical epidemiological characteristic that modulates the pandemic potential of emerging respiratory virus, which may vary depending on the nature of the disease source, population characteristics, source–host interaction, and environmental factors. Methods: We developed a simple likelihood-based framework to estimate the instantaneous asymptomatic proportion of infectious diseases. Taking the COVID-1…
How Transportation Restriction Shapes the Relationship Between Ambient Nitrogen Dioxide and Covid-19 Transmissibility
Background: Several recent studies reported a positive (statistical) association between ambient nitrogen dioxide (NO 2 ) and COVID-19 transmissibility. However, considering the intensive transportation restriction due to lockdown measures that would lead to declines in both ambient NO 2 concentration and COVID-19 spread, the crude or insufficiently adjusted associations between NO 2 and COVID-19 transmissibility might be confounded. This study a…
Using Proper Mean Generation Intervals in Modeling of Covid-19
In susceptible–exposed–infectious–recovered (SEIR) epidemic models, with the exponentially distributed duration of exposed/infectious statuses, the mean generation interval (GI, time lag between infections of a primary case and its secondary case) equals the mean latent period (LP) plus the mean infectious period (IP). It was widely reported that the GI for COVID-19 is as short as 5 days. However, many works in top journals used longer LP or IP w…
The co-circulating transmission dynamics of Sars-CoV-2 Alpha and Eta variants in Nigeria
BACKGROUND: The COVID-19 pandemic poses serious threats to public health globally, and the emerging mutations in SARS-CoV-2 genomes has become one of the major challenges of disease control. In the second epidemic wave in Nigeria, the roles of co-circulating SARS-CoV-2 Alpha (ie, B.1.1.7) and Eta (ie, B.1.525) variants in contributing to the epidemiological outcomes were of public health concerns for investigation. METHODS: We developed a mathema…
Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020
Backgrounds An ongoing outbreak of a novel coronavirus (2019-nCoV) pneumonia hit a major city in China, Wuhan, December 2019 and subsequently reached other provinces/regions of China and other countries. We present estimates of the basic reproduction number, R 0 , of 2019-nCoV in the early phase of the outbreak. Methods Accounting for the impact of the variations in disease reporting rate, we modelled the epidemic curve of 2019-nCoV cases time se…
Low dispersion in the infectiousness of Covid-19 cases implies difficulty in control
The individual infectiousness of coronavirus disease 2019 (COVID-19), quantified by the number of secondary cases of a typical index case, is conventionally modelled by a negative-binomial (NB) distribution. Based on patient data of 9120 confirmed cases in China, we calculated the variation of the individual infectiousness, i.e., the dispersion parameter k of the NB distribution, at 0.70 (95% confidence interval: 0.59, 0.98). This suggests that t…
Age-Period-Cohort Analysis on the Time Trend of Hepatitis B Incidence in Four Prefectures of Southern Xinjiang, China from 2005 to 2017
Objective : The influence of age, period, and cohort on Hepatitis B (HB) incidence in four prefectures of southern Xinjiang, China is still not clear. This paper aims to analyze the long-term trend of the HB incidence in four prefectures of southern Xinjiang, China and to estimate the independent impact of age, period and cohort, as well as to predict the development trend of HB incidence in male and female groups, then to identify the targeted p…
No prominent works on this page.
Age-Period-Cohort Analysis on the Time Trend of Hepatitis B Incidence in Four Prefectures of Southern Xinjiang, China from 2005 to 2017
Objective : The influence of age, period, and cohort on Hepatitis B (HB) incidence in four prefectures of southern Xinjiang, China is still not clear. This paper aims to analyze the long-term trend of the HB incidence in four prefectures of southern Xinjiang, China and to estimate the independent impact of age, period and cohort, as well as to predict the development trend of HB incidence in male and female groups, then to identify the targeted p…
Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020
Backgrounds An ongoing outbreak of a novel coronavirus (2019-nCoV) pneumonia hit a major city in China, Wuhan, December 2019 and subsequently reached other provinces/regions of China and other countries. We present estimates of the basic reproduction number, R 0 , of 2019-nCoV in the early phase of the outbreak. Methods Accounting for the impact of the variations in disease reporting rate, we modelled the epidemic curve of 2019-nCoV cases time se…
Low dispersion in the infectiousness of Covid-19 cases implies difficulty in control
The individual infectiousness of coronavirus disease 2019 (COVID-19), quantified by the number of secondary cases of a typical index case, is conventionally modelled by a negative-binomial (NB) distribution. Based on patient data of 9120 confirmed cases in China, we calculated the variation of the individual infectiousness, i.e., the dispersion parameter k of the NB distribution, at 0.70 (95% confidence interval: 0.59, 0.98). This suggests that t…
Reinfection or Reactivation of Severe Acute Respiratory Syndrome Coronavirus 2
As the pandemic continues, individuals with re-detectable positive (RP) SARS-CoV-2 viral RNA among recovered COVID-19 patients have raised public health concerns. It is imperative to investigate whether the cases with re-detectable positive (RP) SARS-CoV-2 might cause severe infection to the vulnerable population. In this work, we conducted a systematic review of recent literature to investigate reactivation and reinfection among the discharged C…
The Disease Severity and Clinical Outcomes of the Sars-CoV-2 Variants of Concern
With the continuation of the pandemic, many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of increasing the transmissibility of the virus, severity of the infected individuals, and the ability to escape the antibody produced by the vaccines, the four SARS-CoV-2 variants of Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2) have attracted the most wid…
Estimating the Instantaneous Asymptomatic Proportion With a Simple Approach
Background: The asymptomatic proportion is a critical epidemiological characteristic that modulates the pandemic potential of emerging respiratory virus, which may vary depending on the nature of the disease source, population characteristics, source–host interaction, and environmental factors. Methods: We developed a simple likelihood-based framework to estimate the instantaneous asymptomatic proportion of infectious diseases. Taking the COVID-1…
How Transportation Restriction Shapes the Relationship Between Ambient Nitrogen Dioxide and Covid-19 Transmissibility
Background: Several recent studies reported a positive (statistical) association between ambient nitrogen dioxide (NO 2 ) and COVID-19 transmissibility. However, considering the intensive transportation restriction due to lockdown measures that would lead to declines in both ambient NO 2 concentration and COVID-19 spread, the crude or insufficiently adjusted associations between NO 2 and COVID-19 transmissibility might be confounded. This study a…
Using Proper Mean Generation Intervals in Modeling of Covid-19
In susceptible–exposed–infectious–recovered (SEIR) epidemic models, with the exponentially distributed duration of exposed/infectious statuses, the mean generation interval (GI, time lag between infections of a primary case and its secondary case) equals the mean latent period (LP) plus the mean infectious period (IP). It was widely reported that the GI for COVID-19 is as short as 5 days. However, many works in top journals used longer LP or IP w…
The co-circulating transmission dynamics of Sars-CoV-2 Alpha and Eta variants in Nigeria
BACKGROUND: The COVID-19 pandemic poses serious threats to public health globally, and the emerging mutations in SARS-CoV-2 genomes has become one of the major challenges of disease control. In the second epidemic wave in Nigeria, the roles of co-circulating SARS-CoV-2 Alpha (ie, B.1.1.7) and Eta (ie, B.1.525) variants in contributing to the epidemiological outcomes were of public health concerns for investigation. METHODS: We developed a mathema…
Modelling Covid-19 vaccine breakthrough infections in highly vaccinated Israel—The effects of waning immunity and third vaccination dose
In August 2021, a major wave of the SARS-CoV-2 Delta variant erupted in the highly vaccinated population of Israel. The transmission advantage of the Delta variant enabled it to replace the Alpha variant in approximately two months. The outbreak led to an unexpectedly large proportion of breakthrough infections (BTI)–a phenomenon that received worldwide attention. Most of the Israeli population, especially those aged 60+, received their second do…
Multiple Covid-19 Waves and Vaccination Effectiveness in the United States
(1) Background: The coronavirus 2019 (COVID-19) pandemic has caused multiple waves of cases and deaths in the United States (US). The wild strain, the Alpha variant (B.1.1.7) and the Delta variant (B.1.617.2) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were the principal culprits behind these waves. To mitigate the pandemic, the vaccination campaign was started in January 2021. While the vaccine efficacy is less than 1, breakt…
Modelling of Waning of Immunity and Reinfection Induced Antibody Boosting of Sars-CoV-2 in Manaus, Brazil
It was reported that the Brazilian city, Manaus, likely exceeded the herd immunity threshold (presumably 60-70%) in November 2020 after the first wave of COVID-19, based on the serological data of a routine blood donor. However, a second wave started in November 2020, when an even higher magnitude of deaths hit the city. The arrival of the second wave coincided with the emergence of the Gamma (P.1) variant of SARS-CoV-2, with higher transmissibil…
The immune evasion ability of Delta variant is comparable to that of Beta variant in South Africa
We conclude that the immune evasion ability of Beta variant is not stronger than Delta variant, and indeed, the immune evasion abilities of both variants are weak in South Africa
Medicine (12 works) · COVID-19 epidemiological studies (10 works) · Internal Medicine (9 works) · Outbreak (8 works) · Virology (8 works) · Demography (7 works) · Disease (7 works) · Population (7 works) · SARS-CoV-2 and COVID-19 Research (7 works) · 2019-20 coronavirus outbreak (5 works)