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Donato Rigante

Biographic Data

ID7060898
NAMEDonato Rigante
GIVEN NAMESDonato
FAMILY NAMERigante
SIGNATURERIGANTE D
AFFILIATIONSUniversità Cattolica del Sacro Cuore
ORCID0000-0001-7032-7779
VERIFIEDYes
TOTAL WORKS9
TOTAL CITATIONS0
AUTHOR COUNT9
EDITOR COUNT0
FIRST PUBLICATION YEAR2017
LATEST PUBLICATION YEAR2026
H-INDEX0
  • Gonadotropins in Mini-Puberty

    Open Access•Ignazio Cammisa, Donato Rigante et al.•ARTICLE•Children•2026

    Background: Mini-puberty is a transient but critical postnatal activation of the hypothalamic-pituitary-gonadal axis, essential for male gonadal maturation, penile and testicular growth, and future reproductive potential: this physiological hormonal surge is absent or blunted in congenital hypogonadotropic hypogonadism (CHH), often manifesting as micropenis, cryptorchidism, and impaired Sertoli cell proliferation. Objective: The aim of this revie…

  • Neonatal Symptoms in Pediatric Idiopathic Growth Hormone Deficiency

    Open Access•Giorgio Sodero, Donato Rigante et al.•ARTICLE•Children•2025

    In our cohort of pediatric patients with idiopathic GHD, the prevalences of neonatal signs and symptoms of GHD was low, except for neonatal hypoglycemia observed in 27.9% of the analyzed patients. Although these are not specific signs of idiopathic GHD, it is beneficial to investigate this information in the medical history during the clinical assessment of the child

  • The Impact of Acquired Hypothyroidism on the Growth and Metabolic Profiles of Pediatric Patients

    Open Access•Elena Malavolta, Ignazio Cammisa et al.•ARTICLE•Children•2025

    Background : Hypothyroidism is the most common thyroid dysfunction in childhood, resulting from the decreased biological activity of thyroid hormones in tissues. Pediatric patients with hypothyroidism, when left untreated or when thyroid hormone levels fail to normalize despite treatment, may exhibit various complications such as growth retardation, obesity, and hypercholesterolemia. Aim : We conducted a monocentric retrospective study to evaluat…

  • Lipid Profile and Triglyceride-Glucose Index (TyG) Alterations in a Single-Center Cohort of Children Diagnosed with Central Precocious Puberty

    Open Access•Giorgio Sodero, Lucia Celeste Pane et al.•ARTICLE•Children•2024

    Background: A correlation between plasma lipids and timing of pubertal development has been hypothesized, though lipid influence remains unclear in central precocious puberty (CPP). Aim: To assess any possible alterations in the lipid profile and triglyceride glucose index (TyG) in children diagnosed with CPP. Patients and Methods: Retrospective single-center study conducted on children (aged 6.3 ± 2.1 years) evaluated for the suspicion of CPP. R…

  • Predictors of Gastrointestinal Involvement in Children with IgA Vasculitis

    Open Access•Donato Rigante, Cristina Guerriero et al.•ARTICLE•Children•2024

    Background and objective : IgA vasculitis (IgAV), a predominantly pediatric leukocytoclastic disease, has an unpredictable, though largely benign, evolution. The aim of this study was to retrospectively investigate any potential clinical or laboratory predictors of gastrointestinal involvement in a single-center cohort of children with IgAV. Patients and methods : A total of 195 children with a history of IgAV, regularly followed-up for an averag…

  • A Potential Link Between Outcome of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA) Syndrome in Children and Breastfeeding

    Open Access•Donato Rigante, Marcello Candelli•ARTICLE•Children•2024

    Background/Objectives: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome, often referred to as PFAPA syndrome, may enigmatically recur for an undetermined time in affected children: a potential reason to explain its recurring pattern for an unpredictable period or its self-limitation is currently unknown. We explored the relationship between different general, demographic, clinical, and laboratory features of PFAPA …

  • Metabolic Profile of Patients with Smith-Magenis Syndrome

    Open Access•Clelia Cipolla, Linda Sessa et al.•ARTICLE•Children•2023

    Background : Smith-Magenis syndrome (SMS) is caused by either interstitial deletions in the 17p11.2 region or pathogenic variants in the RAI1 gene and is marked by a distinct set of physical, developmental, neurological, and behavioral features. Hypercholesterolemia has been described in SMS, and obesity is also commonly found. Aim : To describe and characterize the metabolic phenotype of a cohort of SMS patients with an age range of 2.9-32.4 yea…

  • Anti-TNF-Related Leukocytoclastic Vasculitis in Ulcerative Colitis

    Open Access•Valentina Giorgio, Elisa Blasi et al.•ARTICLE•International Journal of…•2021

    The need to develop specific recommendations to guide the use of medications for managing skin reactions induced by anti-TNF-α drugs is herein emphasized

  • Early Desquamating Perineal Erythema in a Febrile Infant

    Open Access•Chiara Isidori, Lisa Sebastiani et al.•ARTICLE•International Journal of…•2017

    Background : The occurrence of a distinctive perineal eruption that appears early in infants with Kawasaki disease (KD), the most relevant type of febrile vasculitis of childhood, has received little attention in pediatric reports. KD diagnosis is based on clinical criteria, which can be supported by laboratory abnormalities or positive echocardiography findings: difficulty in diagnosis can be increased by incomplete or atypical presentations, bu…

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  • Early Desquamating Perineal Erythema in a Febrile Infant

    Open Access•Chiara Isidori, Lisa Sebastiani et al.•ARTICLE•International Journal of…•2017

    Background : The occurrence of a distinctive perineal eruption that appears early in infants with Kawasaki disease (KD), the most relevant type of febrile vasculitis of childhood, has received little attention in pediatric reports. KD diagnosis is based on clinical criteria, which can be supported by laboratory abnormalities or positive echocardiography findings: difficulty in diagnosis can be increased by incomplete or atypical presentations, bu…

  • Anti-TNF-Related Leukocytoclastic Vasculitis in Ulcerative Colitis

    Open Access•Valentina Giorgio, Elisa Blasi et al.•ARTICLE•International Journal of…•2021

    The need to develop specific recommendations to guide the use of medications for managing skin reactions induced by anti-TNF-α drugs is herein emphasized

  • Metabolic Profile of Patients with Smith-Magenis Syndrome

    Open Access•Clelia Cipolla, Linda Sessa et al.•ARTICLE•Children•2023

    Background : Smith-Magenis syndrome (SMS) is caused by either interstitial deletions in the 17p11.2 region or pathogenic variants in the RAI1 gene and is marked by a distinct set of physical, developmental, neurological, and behavioral features. Hypercholesterolemia has been described in SMS, and obesity is also commonly found. Aim : To describe and characterize the metabolic phenotype of a cohort of SMS patients with an age range of 2.9-32.4 yea…

  • Lipid Profile and Triglyceride-Glucose Index (TyG) Alterations in a Single-Center Cohort of Children Diagnosed with Central Precocious Puberty

    Open Access•Giorgio Sodero, Lucia Celeste Pane et al.•ARTICLE•Children•2024

    Background: A correlation between plasma lipids and timing of pubertal development has been hypothesized, though lipid influence remains unclear in central precocious puberty (CPP). Aim: To assess any possible alterations in the lipid profile and triglyceride glucose index (TyG) in children diagnosed with CPP. Patients and Methods: Retrospective single-center study conducted on children (aged 6.3 ± 2.1 years) evaluated for the suspicion of CPP. R…

  • Predictors of Gastrointestinal Involvement in Children with IgA Vasculitis

    Open Access•Donato Rigante, Cristina Guerriero et al.•ARTICLE•Children•2024

    Background and objective : IgA vasculitis (IgAV), a predominantly pediatric leukocytoclastic disease, has an unpredictable, though largely benign, evolution. The aim of this study was to retrospectively investigate any potential clinical or laboratory predictors of gastrointestinal involvement in a single-center cohort of children with IgAV. Patients and methods : A total of 195 children with a history of IgAV, regularly followed-up for an averag…

  • A Potential Link Between Outcome of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA) Syndrome in Children and Breastfeeding

    Open Access•Donato Rigante, Marcello Candelli•ARTICLE•Children•2024

    Background/Objectives: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome, often referred to as PFAPA syndrome, may enigmatically recur for an undetermined time in affected children: a potential reason to explain its recurring pattern for an unpredictable period or its self-limitation is currently unknown. We explored the relationship between different general, demographic, clinical, and laboratory features of PFAPA …

  • Neonatal Symptoms in Pediatric Idiopathic Growth Hormone Deficiency

    Open Access•Giorgio Sodero, Donato Rigante et al.•ARTICLE•Children•2025

    In our cohort of pediatric patients with idiopathic GHD, the prevalences of neonatal signs and symptoms of GHD was low, except for neonatal hypoglycemia observed in 27.9% of the analyzed patients. Although these are not specific signs of idiopathic GHD, it is beneficial to investigate this information in the medical history during the clinical assessment of the child

  • The Impact of Acquired Hypothyroidism on the Growth and Metabolic Profiles of Pediatric Patients

    Open Access•Elena Malavolta, Ignazio Cammisa et al.•ARTICLE•Children•2025

    Background : Hypothyroidism is the most common thyroid dysfunction in childhood, resulting from the decreased biological activity of thyroid hormones in tissues. Pediatric patients with hypothyroidism, when left untreated or when thyroid hormone levels fail to normalize despite treatment, may exhibit various complications such as growth retardation, obesity, and hypercholesterolemia. Aim : We conducted a monocentric retrospective study to evaluat…

  • Gonadotropins in Mini-Puberty

    Open Access•Ignazio Cammisa, Donato Rigante et al.•ARTICLE•Children•2026

    Background: Mini-puberty is a transient but critical postnatal activation of the hypothalamic-pituitary-gonadal axis, essential for male gonadal maturation, penile and testicular growth, and future reproductive potential: this physiological hormonal surge is absent or blunted in congenital hypogonadotropic hypogonadism (CHH), often manifesting as micropenis, cryptorchidism, and impaired Sertoli cell proliferation. Objective: The aim of this revie…

Medicine (8 works) · Internal Medicine (7 works) · Pediatrics (4 works) · Dermatology (3 works) · Endocrinology (3 works) · Gastroenterology (3 works) · Growth Hormone and Insulin-like Growth Factors (3 works) · Hormone (3 works) · Adverse effect (2 works) · Birth, Development, and Health (2 works)

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