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Brian H Harvey

Biographic Data

ID7274267
NAMEBrian H Harvey
GIVEN NAMESBrian H
FAMILY NAMEHarvey
SIGNATUREHARVEY B H
AFFILIATIONSNorth-West University
ORCID0000-0002-9864-7894
VERIFIEDYes
TOTAL WORKS6
TOTAL CITATIONS0
AUTHOR COUNT6
EDITOR COUNT0
FIRST PUBLICATION YEAR2020
LATEST PUBLICATION YEAR2024
H-INDEX0
  • Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents

    Open Access•Johané Gericke, Brian H Harvey et al.•ARTICLE•Journal of Ethnopharmacology•2024

  • Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological, pre-clinical and clinical activities

    Open Access•T L Olatunji, Frances Siebert et al.•ARTICLE•Journal of Ethnopharmacology•2022

  • An acute dose-ranging evaluation of the antidepressant properties of Sceletium tortuosum (Zembrin®) versus escitalopram in the Flinders Sensitive Line rat

    Open Access•Johané Gericke, Makhotso Lekhooa et al.•ARTICLE•Journal of Ethnopharmacology•2022

  • Post-weaning Social Isolated Flinders Sensitive Line Rats Display Bio-Behavioural Manifestations Resistant to Fluoxetine: A Model of Treatment-Resistant Depression

    Open Access•Khulekani Mncube, Marisa Möller et al.•ARTICLE•Frontiers in Psychiatry•2021

    Treatment-resistant depression (TRD) complicates the management of major depression (MD). The underlying biology of TRD involves interplay between genetic propensity and chronic and/or early life adversity. By combining a genetic animal model of MD and post-weaning social isolation rearing (SIR), we sought to produce an animal that displays more severe depressive- and social anxiety-like manifestations resistant to standard antidepressant treatme…

  • Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological and clinical activities

    Open Access•T L Olatunji, Frances Siebert et al.•ARTICLE•Journal of Ethnopharmacology•2021

  • Studies on Haloperidol and Adjunctive α-Mangostin or Raw Garcinia mangostana Linn Pericarp on Bio-Behavioral Markers in an Immune-Inflammatory Model of Schizophrenia in Male Rats

    Open Access•Jana Lotter, Marisa Möller et al.•ARTICLE•Frontiers in Psychiatry•2020

    Schizophrenia is a severe brain disorder that is associated with neurodevelopmental insults, such as prenatal inflammation, that introduce redox-immune-inflammatory alterations and risk for psychotic symptoms later in life. Nutraceuticals may offer useful adjunctive benefits. The aim of this study was to examine the therapeutic effects of Garcinia mangostana Linn (GML) and one of its active constituents, α-mangostin (AM), alone and as adjunctive …

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  • Studies on Haloperidol and Adjunctive α-Mangostin or Raw Garcinia mangostana Linn Pericarp on Bio-Behavioral Markers in an Immune-Inflammatory Model of Schizophrenia in Male Rats

    Open Access•Jana Lotter, Marisa Möller et al.•ARTICLE•Frontiers in Psychiatry•2020

    Schizophrenia is a severe brain disorder that is associated with neurodevelopmental insults, such as prenatal inflammation, that introduce redox-immune-inflammatory alterations and risk for psychotic symptoms later in life. Nutraceuticals may offer useful adjunctive benefits. The aim of this study was to examine the therapeutic effects of Garcinia mangostana Linn (GML) and one of its active constituents, α-mangostin (AM), alone and as adjunctive …

  • Post-weaning Social Isolated Flinders Sensitive Line Rats Display Bio-Behavioural Manifestations Resistant to Fluoxetine: A Model of Treatment-Resistant Depression

    Open Access•Khulekani Mncube, Marisa Möller et al.•ARTICLE•Frontiers in Psychiatry•2021

    Treatment-resistant depression (TRD) complicates the management of major depression (MD). The underlying biology of TRD involves interplay between genetic propensity and chronic and/or early life adversity. By combining a genetic animal model of MD and post-weaning social isolation rearing (SIR), we sought to produce an animal that displays more severe depressive- and social anxiety-like manifestations resistant to standard antidepressant treatme…

  • Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological and clinical activities

    Open Access•T L Olatunji, Frances Siebert et al.•ARTICLE•Journal of Ethnopharmacology•2021

  • Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological, pre-clinical and clinical activities

    Open Access•T L Olatunji, Frances Siebert et al.•ARTICLE•Journal of Ethnopharmacology•2022

  • An acute dose-ranging evaluation of the antidepressant properties of Sceletium tortuosum (Zembrin®) versus escitalopram in the Flinders Sensitive Line rat

    Open Access•Johané Gericke, Makhotso Lekhooa et al.•ARTICLE•Journal of Ethnopharmacology•2022

  • Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents

    Open Access•Johané Gericke, Brian H Harvey et al.•ARTICLE•Journal of Ethnopharmacology•2024

Medicine (6 works) · Chemical synthesis and alkaloids (4 works) · Traditional medicine (4 works) · Antidepressant (3 works) · Pharmacology (3 works) · Psychiatry (3 works) · Advanced Synthetic Organic Chemistry (2 works) · Anxiety (2 works) · Behavioural despair test (2 works) · Biology (2 works)

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