Skip to main content

ETHNOS_APP

Home • Search • Journals • List 0

An acute dose-ranging evaluation of the antidepressant properties of Sceletium tortuosum (Zembrin®) versus escitalopram in the Flinders Sensitive Line rat

Bibliographic Data

ID14731024
AuthorsJohané Gericke (0000-0003-0038-3374, North-West University), Makhotso Lekhooa (0000-0002-7819-7697, North-West University, corresponding author), Stephan F Steyn (0000-0002-0023-9711, North-West University), Alvaro Viljoen (0000-0002-6810-2981, Tshwane University of Technology), Alvaro M Viljoen, Brian H Harvey (0000-0002-9864-7894, University of Cape Town)
Year2022
Volume284
Pages114550
Publication date2022-02-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2021.114550
PMID34454055
OpenAlexW3194641163
LanguageEN
Citations received4
References cited57

Antidepressant · Dose-ranging study · Escitalopram · Hippocampus · Traditional medicine · Chemical synthesis and alkaloids · Cholinesterase and Neurodegenerative Diseases · Medicine · Psychedelics and Drug Studies · Internal Medicine

  • Sceletium tortuosum

    Open Access•T L Olatunji, Frances Siebert et al.•Journal of Ethnopharmacology•2022

  • Neuroprotective and neurorestorative properties of Mesembryanthemum tortuosum in a Parkinson's disease zebrafish larvae model

    Open Access•Keagile Lepule, Maxleene Sandasi et al.•Journal of Ethnopharmacology•2025

  • Differential impact of extracts from distinct Sceletium tortuosum chemotypes on central neurotransmitter concentrations in C57BL/6 mice

    Open Access•Catherine H Kaschula, Anna-Mart Engelbrecht et al.•Journal of Ethnopharmacology•2025

  • Unraveling the potential of Morinda officinalis oligosaccharides as an adjuvant of escitalopram in depression treatment and exploring the underlying mechanisms

    Open Access•Shu-Man Pan, Shu‐Man Pan et al.•Journal of Ethnopharmacology•2024

  • Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D

    Madhukar H Trivedi, A John Rush et al.•American Journal of Psychiatry•2006

  • The New Statistics

    Open Access•Geoff Cummings, GEOFF CUMMING•Psychological Science•2014

  • The effects of Sceletium tortuosum (L.) N.E. Br. extract fraction in the chick anxiety-depression model

    Open Access•Jessica M Carpenter, Mary Katherine Jourdan et al.•Journal of Ethnopharmacology•2016

  • Effects of Sceletium tortuosum in rats

    Open Access•Melissa J Loria, Zulfiqar Ali et al.•Journal of Ethnopharmacology•2014

  • Sceletium—A review update

    Open Access•Niklas Gericke, Nigel Gericke et al.•Journal of Ethnopharmacology•2008

  • Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids

    Open Access•Alan L Harvey, Louise Young et al.•Journal of Ethnopharmacology•2011

  • Mesembrine alkaloids

    Open Access•John L Krstenansky•Journal of Ethnopharmacology•2017

  • Sceletium tortuosum

    Open Access•T L Olatunji, Frances Siebert et al.•Journal of Ethnopharmacology•2021

  • High-mesembrine Sceletium extract (TrimesemineTM) is a monoamine releasing agent, rather than only a selective serotonin reuptake inhibitor

    Open Access•D Coetzee, Dirk D Coetzee et al.•Journal of Ethnopharmacology•2016

  • The effects of Sceletium tortuosum in an in vivo model of psychological stress

    Open Access•Carine Smith•Journal of Ethnopharmacology•2011

  • Use of traditional medicine in middle-income countries

    Open Access•Oyinlola Oyebode, Ngianga-Bakwin Kandala et al.•Health Policy and Planning•2016

Unique citing works4
Citations per year1
Citation span2022 - 2025 (4)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 3

Tools

Open DOI
Ethnos_APP • Open Source Project • MIT License • Frontend v2.0.0 • Privacy and Cookies • API Documentation: api.ethnos.app/docs • API Source Code: GitHub • DOI: 10.5281/zenodo.17049435 • Frontend Source Code: GitHub • DOI: 10.5281/zenodo.17050053 • cruz.rio.br • Expectantes Misericordiae