Haoxu Dong
Biographic Data
| ID | 7275945 |
|---|---|
| NAME | Haoxu Dong |
| GIVEN NAMES | Haoxu |
| FAMILY NAME | Dong |
| SIGNATURE | DONG H |
| AFFILIATIONS | Tongji Hospital |
| ORCID | 0000-0003-1605-3900 |
| VERIFIED | Yes |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 6 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2024 |
| LATEST PUBLICATION YEAR | 2027 |
| H-INDEX | 0 |
Integrated serum pharmacochemistry , network pharmacology, untargeted metabolomics and experimental validation to explore the mechanism of Wenjian Qigong Decoction in the treatment of polycystic ovary…
Bushen Antai recipe attenuates recurrent spontaneous abortion by activating Vegfa/p-AKT/Sesn2 to restore trophoblast endoplasmic reticulum homeostasis
ETHNOPHARMACOLOGICAL RELEVANCE: Recurrent spontaneous abortion (RSA) remains a formidable clinical challenge with limited therapeutic options, largely attributed to trophoblast dysfunction as a central pathological mechanism. Bushen Antai recipe (BAR) has demonstrated encouraging clinical and experimental efficacy in pregnancy support. However, its bioactive constituents and molecular mechanisms, especially in the context of trophoblasts, remain …
Integrating network pharmacology and transcriptomics reveals that Bushen Huoxue recipe ameliorates ferroptosis and apoptosis in granulosa cells by regulating PI3K/Akt signaling pathway in premature ov…
BHR effectively ameliorated ovarian function in CTX-induced POI mice by suppressing ferroptosis and apoptosis in GCs. This effect is mechanistically mediated by the activation of the PI3K/Akt signaling pathway. Furthermore, the Hmox1/GPX4 axis may be associated with BHR-mediated inhibition of ferroptosis
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication
In view of ovarian steroidogenesis and luteal construction to explore the effects of Bushen Huoxue recipe in mice of ovarian hyperstimulation
BSHXR restored the abnormally high progesterone level by regulating the CYP11A1 and HSD3B1 expression as well as promoted luteal angiogenesis, which was related with LHCGR-MEK1/2-ERK1/2-VEGFA/FGF2 signaling pathway in the ovary. This effect prevented the fluctuation of sex hormones in COH mice and benefited the outcome of pregnancy
Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone mice
No prominent works on this page.
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication
In view of ovarian steroidogenesis and luteal construction to explore the effects of Bushen Huoxue recipe in mice of ovarian hyperstimulation
BSHXR restored the abnormally high progesterone level by regulating the CYP11A1 and HSD3B1 expression as well as promoted luteal angiogenesis, which was related with LHCGR-MEK1/2-ERK1/2-VEGFA/FGF2 signaling pathway in the ovary. This effect prevented the fluctuation of sex hormones in COH mice and benefited the outcome of pregnancy
Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone mice
Integrating network pharmacology and transcriptomics reveals that Bushen Huoxue recipe ameliorates ferroptosis and apoptosis in granulosa cells by regulating PI3K/Akt signaling pathway in premature ov…
BHR effectively ameliorated ovarian function in CTX-induced POI mice by suppressing ferroptosis and apoptosis in GCs. This effect is mechanistically mediated by the activation of the PI3K/Akt signaling pathway. Furthermore, the Hmox1/GPX4 axis may be associated with BHR-mediated inhibition of ferroptosis
Bushen Antai recipe attenuates recurrent spontaneous abortion by activating Vegfa/p-AKT/Sesn2 to restore trophoblast endoplasmic reticulum homeostasis
ETHNOPHARMACOLOGICAL RELEVANCE: Recurrent spontaneous abortion (RSA) remains a formidable clinical challenge with limited therapeutic options, largely attributed to trophoblast dysfunction as a central pathological mechanism. Bushen Antai recipe (BAR) has demonstrated encouraging clinical and experimental efficacy in pregnancy support. However, its bioactive constituents and molecular mechanisms, especially in the context of trophoblasts, remain …
Integrated serum pharmacochemistry , network pharmacology, untargeted metabolomics and experimental validation to explore the mechanism of Wenjian Qigong Decoction in the treatment of polycystic ovary…
Biology (4 works) · Endocrinology (4 works) · Internal Medicine (4 works) · Medicine (4 works) · Ovarian function and disorders (3 works) · Pregnancy and preeclampsia studies (3 works) · Reproductive System and Pregnancy (3 works) · Andrology (2 works) · Endometriosis Research and Treatment (2 works) · Fetus (2 works)