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Integrated serum pharmacochemistry , network pharmacology, untargeted metabolomics and experimental validation to explore the mechanism of Wenjian Qigong Decoction in the treatment of polycystic ovary syndrome

Bibliographic Data

ID24237176
AuthorsXinbo Wang (0000-0001-8524-9662), Chuyi Liu (0000-0001-5092-9799), Zhuo Zhang (0000-0001-7573-3098), Yanjing Huang (0000-0003-3382-3030), Zhuo Liu (0000-0001-9356-8989), Yufan Song (0000-0003-3498-838X), Runan Hu, Wenwen Ma (0000-0002-1549-3018), Kunkun Song (0000-0003-0384-6485), Mingmin Zhang (0000-0002-9356-5347), Haoxu Dong (0000-0003-1605-3900)
Year2027
Volume374
IssuePt 3
Pages122542
Publication date2027-02-01
Open AccessNo
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.122542
PMID42901065
OpenAlexW7223026463
LanguageEN
References cited45

herbal medicine · Mechanism of Action · network pharmacology · polycystic ovary syndrome · serum pharmacochemistry · Traditional Chinese medicine · untargeted metabolomics · Computational Drug Discovery Methods · Ovarian function and disorders · Traditional Chinese Medicine Analysis

  • Tianjing Zelan formula improves polycystic ovary syndrome by regulating steroid biosynthesis and arachidonic acid metabolism

    Open Access•Huili Zheng, Tingting Shang et al.•Journal of Ethnopharmacology•2026

  • Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication

    Open Access•Runan Hu, Yanjing Huang et al.•Journal of Ethnopharmacology•2024

  • Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula

    Open Access•Li Zhao, Hong Zhang et al.•Journal of Ethnopharmacology•2023

  • Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway

    Open Access•Ruqun Zheng, Haoran Shen et al.•Journal of Ethnopharmacology•2023

  • Metabolomics and serum pharmacochemistry combined with network pharmacology uncover the potential effective ingredients and mechanisms of Yin-Chen-Si-Ni Decoction treating Anit-induced cholestatic liver injury

    Open Access•Yanru Liu, Hui Chen et al.•Journal of Ethnopharmacology•2024

Highly citedNo

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