L Elliot Hong
Biographic Data
| ID | 7369788 |
|---|---|
| NAME | L Elliot Hong |
| GIVEN NAMES | L Elliot |
| FAMILY NAME | Hong |
| SIGNATURE | HONG L E |
| AFFILIATIONS | University of Maryland, Baltimore |
| ORCID | 0000-0002-1472-2659 |
| VERIFIED | Yes |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 6 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2015 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 0 |
Serum neuroactive metabolites of the tryptophan pathway in patients with acute phase of affective disorders
Patients with affective disorders had abnormal tryptophan metabolism, which involved in 5-HT and kynurenine pathway (KP) sub-pathway. Tryptophan metabolites might be potential biomarkers for affective disorders and some metabolites have been associated with remission of depressive symptoms
The Role of Hippocampal Functional Connectivity on Multisystem Subclinical Abnormalities in Schizophrenia
OBJECTIVE: Schizophrenia is associated with excess medical mortality: patients have an average life expectancy one to two decades shorter than the general population. This study investigates the relationship between aberrant hippocampal resting-state functional connectivity in schizophrenia and cumulative subclinical effects of chronic stress on metabolic, cardiovascular, and immune function using the allostatic load index. METHODS: Cumulative st…
Daily and Seasonal Variation in Light Exposure among the Old Order Amish
Exposure to artificial bright light in the late evening and early night, common in modern society, triggers phase delay of circadian rhythms, contributing to delayed sleep phase syndrome and seasonal affective disorder. Studying a unique population like the Old Order Amish (OOA), whose lifestyles resemble pre-industrial societies, may increase understanding of light's relationship with health. Thirty-three participants (aged 25-74, mean age 53.5;…
Fornix Structural Connectivity and Allostatic Load: Empirical Evidence From Schizophrenia Patients and Healthy Controls
OBJECTIVE: The fornix is a white matter tract carrying the fibers connecting the hippocampus and the hypothalamus, two essential stress-regulatory structures of the brain. We tested the hypothesis that allostatic load (AL), derived from a battery of peripheral biomarkers indexing the cumulative effects of stress, is associated with abnormalities in brain white matter microstructure, especially the fornix, and that higher AL may help explain the w…
Antigliadin Antibodies (AGA IgG) Are Related to Neurochemistry in Schizophrenia
Inflammation may play a role in schizophrenia; however, subgroups with immune regulation dysfunction may serve as distinct illness phenotypes with potential different treatment and prevention strategies. Emerging data show that about 30% of people with schizophrenia have elevated antigliadin antibodies of the IgG type, representing a possible subgroup of schizophrenia patients with immune involvement. Also, recent data have shown a high correlati…
Cortisol Reactivity to Stress and Its Association With White Matter Integrity in Adults With Schizophrenia
OBJECTIVES: Although acute hypothalamic-pituitary-adrenal axis response to stress is often adaptive, prolonged responses may have detrimental effects. Many components of white matter structures are sensitive to prolonged cortisol exposure. We aimed to identify a behavioral laboratory assay for cortisol response related to brain pathophysiology in schizophrenia. We hypothesized that an abnormally prolonged cortisol response to stress may be linked…
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Cortisol Reactivity to Stress and Its Association With White Matter Integrity in Adults With Schizophrenia
OBJECTIVES: Although acute hypothalamic-pituitary-adrenal axis response to stress is often adaptive, prolonged responses may have detrimental effects. Many components of white matter structures are sensitive to prolonged cortisol exposure. We aimed to identify a behavioral laboratory assay for cortisol response related to brain pathophysiology in schizophrenia. We hypothesized that an abnormally prolonged cortisol response to stress may be linked…
Fornix Structural Connectivity and Allostatic Load: Empirical Evidence From Schizophrenia Patients and Healthy Controls
OBJECTIVE: The fornix is a white matter tract carrying the fibers connecting the hippocampus and the hypothalamus, two essential stress-regulatory structures of the brain. We tested the hypothesis that allostatic load (AL), derived from a battery of peripheral biomarkers indexing the cumulative effects of stress, is associated with abnormalities in brain white matter microstructure, especially the fornix, and that higher AL may help explain the w…
Antigliadin Antibodies (AGA IgG) Are Related to Neurochemistry in Schizophrenia
Inflammation may play a role in schizophrenia; however, subgroups with immune regulation dysfunction may serve as distinct illness phenotypes with potential different treatment and prevention strategies. Emerging data show that about 30% of people with schizophrenia have elevated antigliadin antibodies of the IgG type, representing a possible subgroup of schizophrenia patients with immune involvement. Also, recent data have shown a high correlati…
The Role of Hippocampal Functional Connectivity on Multisystem Subclinical Abnormalities in Schizophrenia
OBJECTIVE: Schizophrenia is associated with excess medical mortality: patients have an average life expectancy one to two decades shorter than the general population. This study investigates the relationship between aberrant hippocampal resting-state functional connectivity in schizophrenia and cumulative subclinical effects of chronic stress on metabolic, cardiovascular, and immune function using the allostatic load index. METHODS: Cumulative st…
Daily and Seasonal Variation in Light Exposure among the Old Order Amish
Exposure to artificial bright light in the late evening and early night, common in modern society, triggers phase delay of circadian rhythms, contributing to delayed sleep phase syndrome and seasonal affective disorder. Studying a unique population like the Old Order Amish (OOA), whose lifestyles resemble pre-industrial societies, may increase understanding of light's relationship with health. Thirty-three participants (aged 25-74, mean age 53.5;…
Serum neuroactive metabolites of the tryptophan pathway in patients with acute phase of affective disorders
Patients with affective disorders had abnormal tryptophan metabolism, which involved in 5-HT and kynurenine pathway (KP) sub-pathway. Tryptophan metabolites might be potential biomarkers for affective disorders and some metabolites have been associated with remission of depressive symptoms
Medicine (6 works) · Internal Medicine (5 works) · Psychiatry (5 works) · Psychology (5 works) · Neuroscience (3 works) · Schizophrenia (object-oriented programming) (3 works) · Stress Responses and Cortisol (3 works) · Tryptophan and brain disorders (3 works) · Advanced Neuroimaging Techniques and Applications (2 works) · Allostatic load (2 works)