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Serum neuroactive metabolites of the tryptophan pathway in patients with acute phase of affective disorders

Bibliographic Data

ID15518352
AuthorsYanli Li (0000-0001-7139-9993, Peking University), Leilei Wang (0009-0004-4461-8125, Peking University), Junchao Huang (0000-0003-1887-5078, Beijing HuiLongGuan Hospital), Ping Zhang (0000-0003-0663-1850, Peking University), Yanfang Zhou (0000-0002-2924-096X, Beijing HuiLongGuan Hospital), Jinghui Tong (0009-0009-7480-0856, Peking University), Wenjin Chen (0009-0007-8511-7572, Peking University), Mengzhuang Gou (0000-0001-7341-5387, Beijing HuiLongGuan Hospital), Baopeng Tian (Beijing HuiLongGuan Hospital), Wei Li (0000-0002-3581-849X, Beijing HuiLongGuan Hospital), Xingguang Luo, Xingguang Luο (0000-0003-3585-042X, Yale University), Li Tian (0000-0003-2141-781X, University of Tartu), L Elliot Hong (0000-0002-1472-2659, The University of Texas Health Science Center), Chiang‐Shan R Li (0000-0002-9393-1212, Yale University), Chiang-Shan R Li, Yunlong Tan (0000-0002-3522-3912, Peking University, corresponding author)
Year2024
Volume15
Pages1357293-1357293
Publication date2024-04-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1357293
PMID38680780
OpenAlexW4394752155
LanguageEN
References cited63

Patients with affective disorders had abnormal tryptophan metabolism, which involved in 5-HT and kynurenine pathway (KP) sub-pathway. Tryptophan metabolites might be potential biomarkers for affective disorders and some metabolites have been associated with remission of depressive symptoms

Amino acid · Bipolar disorder · Glutamate receptor · Kynurenic acid · Kynurenine · Kynurenine pathway · Lithium (medication · Major depressive disorder · Mania · Mood · Psychiatry · Quinolinic acid · Tryptophan · Young Mania Rating Scale · Bipolar Disorder and Treatment · Chemistry · Medicine · Psychology · Treatment of Major Depression · Tryptophan and brain disorders · Biochemistry · Endocrinology · Internal Medicine

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Highly citedNo

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