Liangwen Xu
Biographic Data
| ID | 7775697 |
|---|---|
| NAME | Liangwen Xu |
| GIVEN NAMES | Liangwen |
| FAMILY NAME | Xu |
| SIGNATURE | XU L |
| AFFILIATIONS | Hangzhou Normal University |
| ORCID | 0000-0002-8410-2965 |
| VERIFIED | Yes |
| TOTAL WORKS | 8 |
| TOTAL CITATIONS | 4 |
| AUTHOR COUNT | 8 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2019 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 1 |
A machine learning screening model for identifying the risk of high-frequency hearing impairment in a general population
The HFHI risk screening model developed based on ML algorithms can more accurately identify residents with HFHI by categorizing them into the high-risk groups, which can further help to identify modifiable and immutable risk factors for residents at high risk of HI and promote their personalized HI prevention or intervention
Association Between Abca1 Gene Polymorphisms and the Risk of Hypertension in the Chinese Han Population
Background: Hypertension is rising as a major public health burden around the world. This study explored the association between single-nucleotide polymorphisms (SNPs) in the adenosine triphosphate (ATP)-Binding Cassette Subfamily A1 (ABCA1) gene and hypertension among Chinese Han adults. Method: A total of 2,296 Han Chinese in southeast China were recruited for this study. We collected medical reports, lifestyle details, and blood samples from i…
Design and Preliminary Realization of a Screening and Early Warning Health Management System for Populations at High Risk for Depression
Depression has a high incidence in the world. Based on the concept of preventive treatment of disease of traditional Chinese medicine, timely screening and early warning of depression in populations at high risk for this condition can avoid, to a certain extent, the dysfunctions caused by depression. This work studied a method to collect information on depression, generate a database of depression features, design algorithms for screening populat…
Construction and Evaluation of a High-Frequency Hearing Loss Screening Tool for Community Residents
Early screening and detection of individuals at high risk of high-frequency hearing loss and identification of risk factors are critical to reduce the prevalence at community level. However, unlike those for individuals facing occupational auditory hazards, a limited number of hearing loss screening models have been developed for community residents. Therefore, this study used lasso regression with 10-fold cross-validation for feature selection a…
Health Education Intervention on Hearing Health Risk Behaviors in College Students
Young people, like college students, are at risk of hearing loss from prolonged and excessive exposure to loud sounds. However, behavioral interventional studies on them are inadequate. This study explored the application of a health belief model to the health education intervention on college students for improving hearing health knowledge, health belief, and hearing behaviors. From November 2017 to September 2018, a cluster randomized controlle…
Association between Leucocyte Telomere Length and Risk of Hearing Loss in the General Population
Limited studies have assessed the relation between telomere length and risk of hearing loss; moreover, they have reported equivocal associations. In the first case-control study, the subjects were chosen from the general population of Zhejiang province in order to assess the association between leucocyte telomere length and risk of hearing loss from 2016 to 2018. A total of 817 cases (55.93 ± 8.99 years) and 817 age-, sex- and residential city-ma…
Associations of Genetic Variations in Abca1 and Lifestyle Factors with Coronary Artery Disease in a Southern Chinese Population with Dyslipidemia
Coronary artery disease has become a major health concern over the past several decades. We aimed to explore the association of single nucleotide polymorphisms (SNPs) in the ATP-binding cassette subfamily A member 1 ( ABCA1 ) and lifestyle factors with coronary artery disease (CAD) in dyslipidemia. This nested case-control study included 173 patients with CAD and 500 matched control individuals (1:3, case: control) from a district in southern Chi…
Relationship between alcohol use, blood pressure and hypertension
Background Past studies have found a strong relationship between alcohol drinking and human health. Methods In this study, we first tested the association of rs671 with alcohol use in 2349 participants in southeast China. We then evaluated the causal impact between alcohol use and cardiovascular traits through a Mendelian randomisation (MR) analysis. Results We found strong evidence for the association of rs671 in the ALDH2 gene with alcohol drin…
Relationship between alcohol use, blood pressure and hypertension
Background Past studies have found a strong relationship between alcohol drinking and human health. Methods In this study, we first tested the association of rs671 with alcohol use in 2349 participants in southeast China. We then evaluated the causal impact between alcohol use and cardiovascular traits through a Mendelian randomisation (MR) analysis. Results We found strong evidence for the association of rs671 in the ALDH2 gene with alcohol drin…
Associations of Genetic Variations in Abca1 and Lifestyle Factors with Coronary Artery Disease in a Southern Chinese Population with Dyslipidemia
Coronary artery disease has become a major health concern over the past several decades. We aimed to explore the association of single nucleotide polymorphisms (SNPs) in the ATP-binding cassette subfamily A member 1 ( ABCA1 ) and lifestyle factors with coronary artery disease (CAD) in dyslipidemia. This nested case-control study included 173 patients with CAD and 500 matched control individuals (1:3, case: control) from a district in southern Chi…
Relationship between alcohol use, blood pressure and hypertension
Background Past studies have found a strong relationship between alcohol drinking and human health. Methods In this study, we first tested the association of rs671 with alcohol use in 2349 participants in southeast China. We then evaluated the causal impact between alcohol use and cardiovascular traits through a Mendelian randomisation (MR) analysis. Results We found strong evidence for the association of rs671 in the ALDH2 gene with alcohol drin…
Association between Leucocyte Telomere Length and Risk of Hearing Loss in the General Population
Limited studies have assessed the relation between telomere length and risk of hearing loss; moreover, they have reported equivocal associations. In the first case-control study, the subjects were chosen from the general population of Zhejiang province in order to assess the association between leucocyte telomere length and risk of hearing loss from 2016 to 2018. A total of 817 cases (55.93 ± 8.99 years) and 817 age-, sex- and residential city-ma…
Construction and Evaluation of a High-Frequency Hearing Loss Screening Tool for Community Residents
Early screening and detection of individuals at high risk of high-frequency hearing loss and identification of risk factors are critical to reduce the prevalence at community level. However, unlike those for individuals facing occupational auditory hazards, a limited number of hearing loss screening models have been developed for community residents. Therefore, this study used lasso regression with 10-fold cross-validation for feature selection a…
Health Education Intervention on Hearing Health Risk Behaviors in College Students
Young people, like college students, are at risk of hearing loss from prolonged and excessive exposure to loud sounds. However, behavioral interventional studies on them are inadequate. This study explored the application of a health belief model to the health education intervention on college students for improving hearing health knowledge, health belief, and hearing behaviors. From November 2017 to September 2018, a cluster randomized controlle…
Association Between Abca1 Gene Polymorphisms and the Risk of Hypertension in the Chinese Han Population
Background: Hypertension is rising as a major public health burden around the world. This study explored the association between single-nucleotide polymorphisms (SNPs) in the adenosine triphosphate (ATP)-Binding Cassette Subfamily A1 (ABCA1) gene and hypertension among Chinese Han adults. Method: A total of 2,296 Han Chinese in southeast China were recruited for this study. We collected medical reports, lifestyle details, and blood samples from i…
Design and Preliminary Realization of a Screening and Early Warning Health Management System for Populations at High Risk for Depression
Depression has a high incidence in the world. Based on the concept of preventive treatment of disease of traditional Chinese medicine, timely screening and early warning of depression in populations at high risk for this condition can avoid, to a certain extent, the dysfunctions caused by depression. This work studied a method to collect information on depression, generate a database of depression features, design algorithms for screening populat…
A machine learning screening model for identifying the risk of high-frequency hearing impairment in a general population
The HFHI risk screening model developed based on ML algorithms can more accurately identify residents with HFHI by categorizing them into the high-risk groups, which can further help to identify modifiable and immutable risk factors for residents at high risk of HI and promote their personalized HI prevention or intervention
Medicine (8 works) · Internal Medicine (6 works) · Biology (4 works) · Genetics (4 works) · Hearing, Cochlea, Tinnitus, Genetics (4 works) · Audiology (3 works) · Computer Science (3 works) · Environmental health (3 works) · Gene (3 works) · Hearing loss (3 works)