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Pi-Kai Chang

Biographic Data

ID7884752
NAMEPi-Kai Chang
GIVEN NAMESPi-Kai
FAMILY NAMEChang
SIGNATURECHANG P
AFFILIATIONSNational Defense Medical Center
ORCID0000-0002-9308-5298
VERIFIEDYes
TOTAL WORKS5
TOTAL CITATIONS0
AUTHOR COUNT5
EDITOR COUNT0
FIRST PUBLICATION YEAR2017
LATEST PUBLICATION YEAR2022
H-INDEX0
  • Proteinuria as a Nascent Predictor of Frailty Among People With Metabolic Syndrome

    Open Access•Pi-Kai Chang, Yuan-Ping Chao et al.•ARTICLE•Frontiers in Public Health•2022

    Frailty is a commonly occurring geriatric condition that increases the risk of adverse health outcomes. The factors and predictors behind frailty are not yet well understood. A better understanding of these factors can enable prevention of frailty in elderly patients. The objective of this study was to determine the association between proteinuria and frailty in US individuals with metabolic syndrome (MetS). Data from the National Health and Nutr…

  • The Combination of Sleep Disorders and Depression Significantly Increases Cancer Risk

    Open Access•Kuo‐Feng Hsu, Fang-Chin Hsu et al.•ARTICLE•International Journal of…•2022

    Introduction: Sleep disorders, depression, and cancer have become increasingly prevalent worldwide. However, it is unknown whether coexistence of sleep disorders and depression influences the risk of cancer development. Therefore, we conducted a nationwide population-based study to examine this association among patients in Taiwan. Materials and Methods: A total of 105,071 individuals diagnosed with cancer and 420,284 age- and sex-matched patient…

  • Risk of Colorectal Cancer in Patients With Attention-Deficit Hyperactivity Disorder

    Open Access•Je‐Ming Hu, Je-Ming Hu et al.•ARTICLE•Frontiers in Psychiatry•2021

    Background: The association between attention-deficit hypersensitivity disorder (ADHD) and the risk of developing colorectal cancer (CRC) is, as yet, to be investigated, and thus, we have conducted this nationwide, cohort study to examine the association in patients from Taiwan. Methods: In this study, 798 individuals with newly diagnosed ADHD and 2,394 (1:3) age-, gender-, and index year- matched controls without ADHD were enrolled, between 2000…

  • Risk for Irritable Bowel Syndrome in Patients with Helicobacter Pylori Infection

    Open Access•Chia-Ming Liang, Chih‐Hsiung Hsu et al.•ARTICLE•International Journal of…•2020

    Based on a retrospective follow-up, nationwide study in Taiwan, H. pylori infection was associated with an increased risk of IBS; however, aggressive H. pylori infection eradication therapy can also reduce the risk of IBS. Further underlying biological mechanistic research is needed

  • Neuroligin 2 R215H Mutant Mice Manifest Anxiety, Increased Prepulse Inhibition, and Impaired Spatial Learning and Memory

    Open Access•Chia‐Hsiang Chen, Chia-Hsiang Chen et al.•ARTICLE•Frontiers in Psychiatry•2017

    Neuroligin 2 ( NLGN2 ) is a postsynaptic adhesion protein that plays an essential role in synaptogenesis and function of inhibitory neuron. We previously identified a missense mutation R215H of the NLGN2 in a patient with schizophrenia. This missense mutation was shown to be pathogenic in several cell-based assays. The objective of this study was to better understand the behavioral consequences of this mutation in vivo . We generated a line of tr…

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  • Neuroligin 2 R215H Mutant Mice Manifest Anxiety, Increased Prepulse Inhibition, and Impaired Spatial Learning and Memory

    Open Access•Chia‐Hsiang Chen, Chia-Hsiang Chen et al.•ARTICLE•Frontiers in Psychiatry•2017

    Neuroligin 2 ( NLGN2 ) is a postsynaptic adhesion protein that plays an essential role in synaptogenesis and function of inhibitory neuron. We previously identified a missense mutation R215H of the NLGN2 in a patient with schizophrenia. This missense mutation was shown to be pathogenic in several cell-based assays. The objective of this study was to better understand the behavioral consequences of this mutation in vivo . We generated a line of tr…

  • Risk for Irritable Bowel Syndrome in Patients with Helicobacter Pylori Infection

    Open Access•Chia-Ming Liang, Chih‐Hsiung Hsu et al.•ARTICLE•International Journal of…•2020

    Based on a retrospective follow-up, nationwide study in Taiwan, H. pylori infection was associated with an increased risk of IBS; however, aggressive H. pylori infection eradication therapy can also reduce the risk of IBS. Further underlying biological mechanistic research is needed

  • Risk of Colorectal Cancer in Patients With Attention-Deficit Hyperactivity Disorder

    Open Access•Je‐Ming Hu, Je-Ming Hu et al.•ARTICLE•Frontiers in Psychiatry•2021

    Background: The association between attention-deficit hypersensitivity disorder (ADHD) and the risk of developing colorectal cancer (CRC) is, as yet, to be investigated, and thus, we have conducted this nationwide, cohort study to examine the association in patients from Taiwan. Methods: In this study, 798 individuals with newly diagnosed ADHD and 2,394 (1:3) age-, gender-, and index year- matched controls without ADHD were enrolled, between 2000…

  • Proteinuria as a Nascent Predictor of Frailty Among People With Metabolic Syndrome

    Open Access•Pi-Kai Chang, Yuan-Ping Chao et al.•ARTICLE•Frontiers in Public Health•2022

    Frailty is a commonly occurring geriatric condition that increases the risk of adverse health outcomes. The factors and predictors behind frailty are not yet well understood. A better understanding of these factors can enable prevention of frailty in elderly patients. The objective of this study was to determine the association between proteinuria and frailty in US individuals with metabolic syndrome (MetS). Data from the National Health and Nutr…

  • The Combination of Sleep Disorders and Depression Significantly Increases Cancer Risk

    Open Access•Kuo‐Feng Hsu, Fang-Chin Hsu et al.•ARTICLE•International Journal of…•2022

    Introduction: Sleep disorders, depression, and cancer have become increasingly prevalent worldwide. However, it is unknown whether coexistence of sleep disorders and depression influences the risk of cancer development. Therefore, we conducted a nationwide population-based study to examine this association among patients in Taiwan. Materials and Methods: A total of 105,071 individuals diagnosed with cancer and 420,284 age- and sex-matched patient…

Confidence interval (4 works) · Environmental health (4 works) · Internal Medicine (4 works) · Medicine (4 works) · Population (4 works) · Psychiatry (3 works) · Cancer (2 works) · Cohort (2 works) · Cohort study (2 works) · Cumulative incidence (2 works)

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