Risk of Colorectal Cancer in Patients With Attention-Deficit Hyperactivity Disorder
A Nationwide, Population-Based Cohort Study
Bibliographic Data
| ID | 15523246 |
|---|---|
| Authors | Je‐Ming Hu (0000-0002-7377-0984, National Defense Medical Center), Je-Ming Hu, Chia‐Cheng Lee (0000-0002-7450-504X, Tri-Service General Hospital), Chia-Cheng Lee, Tzu-Chiao Lin (0000-0003-1479-5396, National Defense Medical Center), Chi‐Hsiang Chung (0000-0002-4576-9900, Tri-Service General Hospital), Chaoyang Chen (0000-0001-5196-8781, Tri-Service General Hospital), Chao-Yang Chen, Pi-Kai Chang (0000-0002-9308-5298, National Defense Medical Center), Cheng-Wen Hsiao (0000-0002-1141-0211, National Defense Medical Center), Chien‐An Sun (0000-0001-9041-0537, Fu Jen Catholic University), Nian‐Sheng Tzeng (0000-0001-5881-7089, Tri-Service General Hospital, corresponding author), Wu‐Chien Chien (0000-0002-3286-0780, Taiwan Nurses Association, corresponding author) |
| Year | 2021 |
| Volume | 12 |
| Pages | 537137-537137 |
| Publication date | 2021-02-05 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2021.537137 |
| PMID | 33613335 |
| OpenAlex | W3128103746 |
| Language | EN |
| Citations received | 1 |
| References cited | 77 |
Background: The association between attention-deficit hypersensitivity disorder (ADHD) and the risk of developing colorectal cancer (CRC) is, as yet, to be investigated, and thus, we have conducted this nationwide, cohort study to examine the association in patients from Taiwan. Methods: In this study, 798 individuals with newly diagnosed ADHD and 2,394 (1:3) age-, gender-, and index year- matched controls without ADHD were enrolled, between 2000 and 2013, from the Longitudinal Health Insurance Database, a subset of the National Health Insurance Research Database in Taiwan. The cumulative incidence of CRC was assessed in each cohort by the Kaplan-Meier method. The multivariate Cox proportional hazards model was used to estimate the crude, and the adjusted hazards ratios (HRs) with 95% confidence intervals (CIs), was conducted to estimate the association between ADHD and CRC. Results: The Kaplan-Meier analysis revealed that the cumulative incidence of CRC was significantly higher in patients with ADHD than in those without it (log rank test, p p Conclusion: This retrospective cohort study depicts the evidence that ADHD was associated with the increased risk of CRC. Further studies are needed to confirm the association and the underlying mechanisms
Cancer · Cohort · Cohort study · Colorectal cancer · Confidence interval · Cumulative incidence · Environmental health · Hazard ratio · Incidence (geometry · Methylphenidate · Population · Proportional hazards model · Psychiatry · Retrospective cohort study · Adolescent and Pediatric Healthcare · Attention Deficit Hyperactivity Disorder · Bipolar Disorder and Treatment · Medicine · Internal Medicine · Oncology
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2026 - 2026 (1) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 1 |