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Zixiang Gao

Biographic Data

ID8255552
NAMEZixiang Gao
GIVEN NAMESZixiang
FAMILY NAMEGao
SIGNATUREGAO Z
AFFILIATIONSBeijing University of Chinese Medicine
ORCID0000-0002-4345-8201
VERIFIEDYes
TOTAL WORKS6
TOTAL CITATIONS0
AUTHOR COUNT6
EDITOR COUNT0
FIRST PUBLICATION YEAR2022
LATEST PUBLICATION YEAR2026
H-INDEX0
  • Effects of running distance on per-step and cumulative lower-extremity loading during a simulated treadmill half marathon

    Open Access•Wenjing Quan, Huiyu Zhou et al.•ARTICLE•Frontiers in Public Health•2026

    Background The cumulative damage impulses have been proposed as a crucial parameter for analyzing joint kinetics and tissue loading during prolonged running. Although prolonged running may have detrimental effects, research focusing on the bones and soft tissues of the lower extremity remains limited. Therefore, this study aimed to examine how treadmill half-marathons influence biomechanical variables in high-performing endurance runners. We addi…

  • Qianlie Beixi Capsules Ameliorate Diabetes-Induced Erectile Dysfunction via Modulation of the HIF-1α/Vegf Signaling Pathway

    Open Access•Longji Sun, Zhechao Lin et al.•ARTICLE•American Journal of Men s Health•2026

    Diabetic-induced erectile dysfunction (DIED) is a frequent complication of diabetes mellitus. Qianlie Beixi Capsules, a formulation of traditional Chinese medicine, have long been used for its management. The effectiveness of Qianlie Beixi Capsules in treating DIED was evaluated together with an exploration of their possible mechanism of action. Streptozotocin (STZ) was administered to rats to induce diabetes, with confirmation of erectile dysfun…

  • Hirudin-Based Treatment of Diabetes-Induced Erectile Dysfunction Through Inhibition of the HIF-1α to Regulate RhoA/Rock Signaling Pathway

    Open Access•Longji Sun, Nianwen Huang et al.•ARTICLE•American Journal of Men s Health•2025

    Diabetes-induced erectile dysfunction (DIED) is a type of refractory erectile dysfunction which can be clinically treated using the traditional Chinese medicine leech whose main ingredient is hirudin. Oxidative stress can damage vascular endothelial cells, affect blood circulation, and induce fibrosis of smooth muscle cells. This study assessed the efficacy of hirudin in treating DIED before exploring its potential mechanism of action. DIED was i…

  • Bioinformatics Combined With Experimental Modeling to Study the Molecular Mechanism of Xuefu Zhuyu Decoction to Improve Erectile Dysfunction Associated With Asthma in Rats

    Open Access•Junlong Feng, Sheng Deng et al.•ARTICLE•American Journal of Men s Health•2024

    Asthma is associated with chronic systemic inflammation, and inflammatory factors can damage vascular endothelial cells, thus impairing erectile function (ED). Xuefu Zhuyu decoction (XFZYD) can inhibit inflammation and promote angiogenesis, which in turn improves asthma as well as ED, but its exact mechanism of action is not yet clear. This study investigates the mechanism underlying the beneficial effect of XFZYD on asthma-associated ED. High-pe…

  • Guijiajiao-Lujiaojiao Synergistically Promote Spermatogenesis in Tripterygium Wilfordii Polyglycoside–Induced Oligoasthenozoospermia Rats via PI3K/AKT Signaling Pathway

    Open Access•Nianwen Huang, Haisong Li et al.•ARTICLE•American Journal of Men s Health•2024

    Guijiajiao-Lujiaojiao (GL) is a combination of Traditional Chinese Medicine (TCM) that can be used to treat oligoasthenozoospermia (OAS). However, its mechanistic role in OAS needs to be better understood and necessitates more studies. This study was planned to investigate GL’s therapeutic effects and its mechanistic role in the tripterygium wilfordii polyglycoside (GTW)-induced OAS rat model. In total, 60 Sprague–Dawley (SD) rats at 8 weeks of a…

  • Understanding Foot Loading and Balance Behavior of Children with Motor Sensory Processing Disorder

    Open Access•Lin Yu, Peimin Yu et al.•ARTICLE•Children•2022

    Sensory processing disorder (SPD) could influence the neuromuscular response and adjustment to external sensory discrimination and lead to disruptions in daily locomotion. The objective of the current study was to compare plantar loadings and foot balance during walking, running and turning activities in SPD children in order to reveal the behavioral strategy of movement and balance control. Six SPD children and six age-match healthy controls par…

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  • Understanding Foot Loading and Balance Behavior of Children with Motor Sensory Processing Disorder

    Open Access•Lin Yu, Peimin Yu et al.•ARTICLE•Children•2022

    Sensory processing disorder (SPD) could influence the neuromuscular response and adjustment to external sensory discrimination and lead to disruptions in daily locomotion. The objective of the current study was to compare plantar loadings and foot balance during walking, running and turning activities in SPD children in order to reveal the behavioral strategy of movement and balance control. Six SPD children and six age-match healthy controls par…

  • Bioinformatics Combined With Experimental Modeling to Study the Molecular Mechanism of Xuefu Zhuyu Decoction to Improve Erectile Dysfunction Associated With Asthma in Rats

    Open Access•Junlong Feng, Sheng Deng et al.•ARTICLE•American Journal of Men s Health•2024

    Asthma is associated with chronic systemic inflammation, and inflammatory factors can damage vascular endothelial cells, thus impairing erectile function (ED). Xuefu Zhuyu decoction (XFZYD) can inhibit inflammation and promote angiogenesis, which in turn improves asthma as well as ED, but its exact mechanism of action is not yet clear. This study investigates the mechanism underlying the beneficial effect of XFZYD on asthma-associated ED. High-pe…

  • Guijiajiao-Lujiaojiao Synergistically Promote Spermatogenesis in Tripterygium Wilfordii Polyglycoside–Induced Oligoasthenozoospermia Rats via PI3K/AKT Signaling Pathway

    Open Access•Nianwen Huang, Haisong Li et al.•ARTICLE•American Journal of Men s Health•2024

    Guijiajiao-Lujiaojiao (GL) is a combination of Traditional Chinese Medicine (TCM) that can be used to treat oligoasthenozoospermia (OAS). However, its mechanistic role in OAS needs to be better understood and necessitates more studies. This study was planned to investigate GL’s therapeutic effects and its mechanistic role in the tripterygium wilfordii polyglycoside (GTW)-induced OAS rat model. In total, 60 Sprague–Dawley (SD) rats at 8 weeks of a…

  • Hirudin-Based Treatment of Diabetes-Induced Erectile Dysfunction Through Inhibition of the HIF-1α to Regulate RhoA/Rock Signaling Pathway

    Open Access•Longji Sun, Nianwen Huang et al.•ARTICLE•American Journal of Men s Health•2025

    Diabetes-induced erectile dysfunction (DIED) is a type of refractory erectile dysfunction which can be clinically treated using the traditional Chinese medicine leech whose main ingredient is hirudin. Oxidative stress can damage vascular endothelial cells, affect blood circulation, and induce fibrosis of smooth muscle cells. This study assessed the efficacy of hirudin in treating DIED before exploring its potential mechanism of action. DIED was i…

  • Effects of running distance on per-step and cumulative lower-extremity loading during a simulated treadmill half marathon

    Open Access•Wenjing Quan, Huiyu Zhou et al.•ARTICLE•Frontiers in Public Health•2026

    Background The cumulative damage impulses have been proposed as a crucial parameter for analyzing joint kinetics and tissue loading during prolonged running. Although prolonged running may have detrimental effects, research focusing on the bones and soft tissues of the lower extremity remains limited. Therefore, this study aimed to examine how treadmill half-marathons influence biomechanical variables in high-performing endurance runners. We addi…

  • Qianlie Beixi Capsules Ameliorate Diabetes-Induced Erectile Dysfunction via Modulation of the HIF-1α/Vegf Signaling Pathway

    Open Access•Longji Sun, Zhechao Lin et al.•ARTICLE•American Journal of Men s Health•2026

    Diabetic-induced erectile dysfunction (DIED) is a frequent complication of diabetes mellitus. Qianlie Beixi Capsules, a formulation of traditional Chinese medicine, have long been used for its management. The effectiveness of Qianlie Beixi Capsules in treating DIED was evaluated together with an exploration of their possible mechanism of action. Streptozotocin (STZ) was administered to rats to induce diabetes, with confirmation of erectile dysfun…

Medicine (4 works) · Erectile dysfunction (3 works) · Biochemistry (2 works) · Chemistry (2 works) · Hormonal and reproductive studies (2 works) · Internal Medicine (2 works) · Lower Extremity Biomechanics and Pathologies (2 works) · Nitric oxide (2 works) · Pharmacology (2 works) · Sexual function and dysfunction studies (2 works)

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