Kallur N Saraswathy
Biographic Data
| ID | 86223 |
|---|---|
| NAME | Kallur N Saraswathy |
| GIVEN NAMES | Kallur N |
| FAMILY NAME | Saraswathy |
| SIGNATURE | SARASWATHY K N |
| AFFILIATIONS | University of Delhi |
| ORCID | 0000-0002-0826-9675 |
| VERIFIED | Yes |
| TOTAL WORKS | 53 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 53 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1980 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Adolescent Romantic Breakup and Substance Use Among Emerging Adults in Delhi-NCR, India
BACKGROUND: While life-course research has emphasized the role of early-life adversity in shaping substance use trajectories, less attention has been paid to developmentally normative yet emotionally salient experiences, such as adolescent romantic breakups (ARBs). This study examined associations between ARBs and substance use patterns (alcohol, tobacco, and cannabis) and addiction-related risk among emerging adults in the Delhi National Capital…
Physical activity and sedentary behavior patterns in cognitive impairment: Findings from a cross-sectional study in Punjab, North India
Physical activity (PA) and sedentary behavior (SB) are recognized as potential factors affecting cognitive function; however, there is limited evidence of their association with cognitive impairment (CI) in Indian populations. The present study aimed to investigate the role of PA and SB in CI among adults living in rural communities in the Mansa district of Punjab, India. The study included 1206 adults of both sexes, living in rural Punjab. Socio…
Adverse Childhood Experiences in Obesity and Hypertension Among Young Adults in Delhi‐ NCR , India
OBJECTIVES: Despite growing evidence linking adverse childhood experiences (ACEs) with physical health conditions such as obesity and hypertension, research in low- and middle-income countries (LMICs), including India, remains limited. This study aims to examine the relationship between ACE exposure and the risk of overweight/obesity and hypertension among young adults in Delhi-NCR, India. METHODS: The present cross-sectional study involved 1702 …
Attention Deficit Hyperactivity Disorder in Obesity and Hypertension: A Study Among Young Adults in Delhi NCR , India
OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder increasingly recognized as an adult health concern. It is linked to behavioral disinhibitions that are studied to be associated with mental and physical health adversities, including obesity and hypertension, due to potential common genetic and environmental underpinnings. These connections remain underexplored, particularly in the Indian context. Hence, t…
Micronutrient Deficiencies and Association With Hypertension: The Role of Folate, Vitamin B12 , and Homocysteine
Objectives Folate and vitamin B12 are essential micronutrients involved in one‐carbon metabolism. Deficiencies in these nutrients can elevate homocysteine levels, a recognized risk factor for hypertension. This study investigates the prevalence of folate and vitamin B12 deficiencies, hyperhomocysteinemia, and their association with hypertension in a North Indian population. Methods This cross‐sectional study analyzed data from 1398 adult particip…
Obesity in Low‐ and Middle‐Income Countries: Sex‐Specific Sociocultural Determinants in High‐Risk Rural Punjab, India
The higher central obesity among women reflects gendered vulnerabilities shaped by socioeconomic and educational disparities. The coexistence of high central obesity and sedentary behavior in a transitioning rural context highlights the shifting sociocultural landscape of obesity in LMICs. Age-related decrease in general but persistent central obesity warrants longitudinal biocultural investigations
Knowledge, attitude, and practices of beta thalassemia: A cross-sectional study among young adults in Delhi-NCR, India
The study highlights the need for targeted awareness campaigns among young adults aimed at encouraging positive attitude, practices, and mitigation of associated stigma. College healthcare programs, compulsory inclusion of thalassemia in all high school or college curriculums, and community outreach programs can be effective measures in promoting awareness, thereby enabling the youth to make informed reproductive planning. This can further lay th…
Prevalence and predictors of positive childhood experiences and their relationship with adverse childhood experiences among young adults in Delhi-NCR, India
Background: Although positive childhood experiences (PCEs) have been reported to be crucial for healthy development and better mental and physical health outcomes, their epidemiology and relationship with adverse childhood experiences (ACE) exposure in low and middle-income countries, including India remain underexplored. Aims: The present study aimed to ascertain the prevalence and predictors of PCE exposure and understand the relationship betwe…
The self as a resource: A qualitative study of women coping with infertility in north India
Indian Society is pro-natalist, often placing the social burden of infertility on women. This paper aims to bring forth how 30 women seeking infertility treatment at a public hospital in Delhi cope with the condition. Using purposive sampling, in-depth interviews were conducted with the women. Thematic analysis of the interviews revealed seven themes: Infertility and resilience: Hope and determination; Infertility as destiny: Attribution to God a…
Suicide and suicide behavior: A qualitative study in Telangana, India
This study aimed to understand the perceptions and experiences of suicide attempters in order to suggest potential initiatives to reduce the suicide burden in rural India. The study is based on 46 in-depth interviews with suicide attempters and 4 focus group discussions with their family members. Interview content analysis revealed information related to four anticipated themes: the characteristics of a suicide attempt are complex; suicide attemp…
Gender Differences in Memory Performance Among Individuals with Cognitive Impairment: A Population-based Study from Rural Haryana, India
Background Cognitive impairment (CI) is a major public health concern among the geriatric population and affects around 50 million people worldwide. The prevalence of CI ranges from 5.1% to 41%, and it is considered an initial stage for conditions like acute dementia, Alzheimer's disease, and schizophrenia. However, diagnosing CI is controversial due to the absence of clear clinical criteria, leading to memory complaints and retained cognitive ab…
Adverse childhood experiences in mental health of young adults: An exploratory study from Delhi-NCR, India
BACKGROUND: Despite the growing realization regarding the importance of adverse childhood experiences (ACEs) in adult health outcomes, this area of research has received little scientific attention in low- and middle-income countries, including India. AIMS: To understand the overall and domain-specific association of exposure to ACEs with current depression, anxiety, stress, and well-being among young adults of Delhi-NCR. METHODS: This cross-sect…
Knowledge, attitude, and practice of infertility: A comparative study in infertile and fertile Indian women
For women who are trying to conceive, it is critical to assess their general knowledge regarding fertility and fertility-awareness practices to identify the fertile window and their agency to achieve pregnancy. The couple’s ability to deal with the infertility issue may be influenced by their beliefs and attitudes concerning infertility, which are based on social and cultural influences as well as their inner aspirations. As a result, it’s critic…
How Human Became Fat? An Anthropological Approach to the Development of Fatnessin Humans
Evolutionary success of Homo sapiens is best understood by referring to natural selection on the twofold structure of inheritance, that is, gene and culture and also their interaction over time. Socioeconomic and technological variations have transformed lifestyles over the years. In tandem, deviations in food and physical activity forms have been crucial to the emergence of higher fatness among the world’s populations. The burden of obesity and …
Incidence and determinants of hysterectomy among North Indian women: An 8-year follow-up study
Background: Despite indications of a rapid increase in the number of hysterectomies performed in India, very few studies have methodically investigated the rate and determinants of the incidence of hysterectomy. The present study aims to estimate the rate of incidence of hysterectomy and identify predictors/determinants of incident hysterectomy in a cohort of North Indian women. Methods: In the present study, a cohort of 1,009 ever-married North …
Neplodnost i pretilost: Studija poprečnog presjeka u žena u sjevernoj Indiji
The present study assessed the relationship between primary infertility and obesity in women of Delhi, India, independently, and in light of various demographic trait, lifestyle and reproductive variables. The present study was a part of a major project funded by the National Commission for Women of India, Government of India. The data were collected from 334 women, including 167 fertile and 167 infertile individuals. A two-part pretested modifie…
Somatotype Characteristics of a Mendelian Population from North India and Its association with Cognitive Impairment and Depression
The present article aims to understand the somatotype characteristics and its association with cognitive impairment (CI) and depression among 768 Jat men and women aged 30–80 years from an Mendelian population of north India. The somatotypes are evaluated using the Heath–Carter protocol. Cognition status is assessed through Mini-Mental State Examination scale, while the depression status is determined using Beck’s depression inventory questionnai…
Struggling with Primary Infertility: Psychological Well-Being and Associated Factors in North Indian Women
The study aimed to understand the effect of primary infertility on the psychological well-being of women. In addition, the study has assessed the impact of socio-demographic variables, reproductive trajectories and lifestyle variables on psychological well-being independently and in light of their dynamic interaction among North Indian women. This study was conducted among 250 infertile women with primary infertility attending the Gynaecology OPD…
Trends of folate, vitamin B 12 , and homocysteine levels in different trimesters of pregnancy and pregnancy outcomes
Objective To evaluate the effect of folate and vitamin B 12 levels on pregnancy progression and outcomes. Methods The present study is a prospective follow up study of 100 pregnant women. Biochemical investigations (plasma homocysteine, folate, and vitamin B 12 levels) were performed on all pregnant women in first, second, and third trimesters. Nonparametric tests were used to compare the differences in median levels and odds ratio analysis for t…
Prevalence of Hypertension and Adiposity Indicators Among Children and Adolescents of Meghwal Community: A Cross-sectional Study from Udaipur, Rajasthan (India)
Background: Early-age cardiometabolic disorders have a profound impact on adult health status. Studies indicated elevated blood pressure and increased adiposity among children and adolescents to be significantly correlated with adult cardiovascular diseases (CVDs). Aim: The study aims to estimate the prevalence of hypertension and adiposity indicators and their association among children and adolescents of Meghwal community, Rajasthan. Methods: T…
Prevalence of cardiovascular risk factors among tribal and non‐tribal populations with East Asian Ancestry from North East India
OBJECTIVES: The distribution of hypertension, type 2 diabetes, dyslipidemia, and obesity variables were studied among tribal and non-tribal populations with East Asian ancestry from northeast India. METHODS: Data pertaining to somatometric measurements, blood pressure, lipid profile, and fasting blood glucose were collected from 1916 participants (Mizo-422, Liangmai-352, and Meitei-1142) of both sexes older than 18 years. Two-way ANOVA and chi sq…
Impaired Homocysteine Metabolism Associated with High Plasma Interleukin- 17A Levels, a Pro-Atherogenic Marker, in an Endogamous Population of North India
None of the physiological, anthropometric and lipid variables were different between the two groups. Foxp3 mRNA expression levels were relatively lower, and plasma IL-10 levels were found to be comparable among IHM and NHM group. However, significantly higher IL-17A levels and relatively high LDL cholesterol levels were present in the IHM group as compared with NHM. Our findings suggest that the Jats of Haryana, North India, exhibiting high level…
Biological and Social Determinants of Fertility Behaviour among the Jat Women of Haryana State, India
Fertility is a way through which human beings biologically replace themselves in order to continue their existence on earth. The present paper therefore attempts to study the factors affecting fertility among the Jat women of Haryana state. A household survey was conducted in 15 villages of Palwal district in which the concentration of Jats was found to be highest and 1014 ever married women were interviewed. Age at marriage, present age, educati…
An assessment study of CVD related risk factors in a tribal population of India
In the present study, hypertension, high BMI levels, MS and abdominal obesity have been found to be high among the studied population. The status of the population with respect to these abnormalities implicates susceptibility of the community towards various common disorders. The prevention and treatment intervention programs should be implemented taking into consideration age and gender
Socio-Economic Characteristics of Alcohol Dependence Among Meiteis of Manipur: A Community Based Study
Study of Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Anemia Among the Tamil Brahmins of Delhi
The distribution of G-6-PD deficiency and sickle cell anemia was studied among the Tamil Brahmins of Delhi. Blood samples were collected from 147 individuals out of whom 68 were males and 79 females. The detection of G-6-PD deficiency was done by Methemoglobin reduction test. Slide test using 2 percent sodium metabisulphite was used for detection of sickle cell trait. Low frequency of 2.72 percent G-6-PD deficient individuals was observed. Sickle…
Delusions — a Study in Sex Differences
Glucose-6-Phosphate Dehydrogenase Deficiency Among Thoti of Andhra Pradesh
"Glucose-6-Phosphate Dehydrogenase Deficiency Among Thoti of Andhra Pradesh." Journal of Human Ecology, 10(4), pp. 325–326
A Modified Method of Haemoglobin Typing From Bloodstains: An Eclectic Approach
Haemoglobin is the major protein of human red cells, comprising about 95 per cent of their dry weight. He is important both in anthropology and forensic serology u it exhibits a very large number of genetic variants, a few of which are comparatively common and conveniently detectable in fresh blood by electrophoresis Of these, the most common variant is probably haemoglobin S. Differentiation of He A. F. S and C from dried blood stains in crimina…
Incidence of Nestroft-positive Among the Kolams of District Adilabad, Andhra Pradesh
Kolam is a primitive tribal population inhabiting Adilabad district of Andhra Pradesh and practicing a high degree of consanguinity. Sickle cell anemia is not the only haemoglobinopathy found among the Indian tribes. Other Hb variants like HbE, HbC, HbD and the structural defects in the synthesis of haemoglobin in the form of alpha- and beta –thalassaemias may also be present. For the extensive screening of the population for abnormal haemoglobin…
Decadal Distribution of Inbreeding among Thoti – A Small Primitive Mendelian Population
The Thoti is a small primitive tribal population practicing high percentage (77.64%) of consanguineous marriage. The decadal analysis also show the high percentage of consanguinity prevalent in this population during the past four decades. The coefficient of inbreeding for autosomal and sex-linked gene was found to be 0.0356 and 0.0340, respectively. When comp ared with other tribal population of Andhra Pradesh, higher percentage of consanguinity…
Incidence of Sickle Cell Haemoglobin among the Thotis of District Adilabad, Andhra Pradesh
The study deals with the incidence of sickle cell anemia among the Thotis, a primitive tribe of Andhra Pradesh. The sample comprises of 397 individuals (188 males and 209 females). Among the 12.84 percent individuals who had sickle cell diseases, 9.32 percent were heterozygous (AS) for sickle cell trait while 2.52 percent were homozygous (SS). Genes A and S have the frequ encies of 0.92 and 0.08, respectively. Generation-wise comparison of the di…
Glucose 6-phosphate Dehydrogenase Deficiency among the Kolams of Adilabad, Andhra Pradesh
Kolam is a primitive tribal population inhabiting Adilabad district of Andhra Pradesh and practicing a high degree of consa nguinity. Data are presented here on the incidence of G6PD deficiency, generational variation and the effect of consanguinity on its distribution among them. The Sample consisted of 454 individuals out of which 226 were males and 228 were females. Overall frequency of Gd- allele was 0.1151 in males and .0373 among the female…
Fertility and the Influencing Factors among the Kolams
An attempt has been made to determine the extent of contribution of various biological and socio-economic factors respectively, when taken together in explaining the fertility variance among the Kolams. The dependent variable is the number of live-born children and the independent variables in the present study are. Presentage of the mother, Age at menarche, Age at first conception, Type of marriage, Experience of infant death in any or both of t…
Incidence of Sickle Cell Haemoglobin among the Kolams of District Adilabad, Andhra Pradesh
The study deals with the incidence of sickle cell anemia among the Thotis, a primitive tribe of Andhra Pradesh. The sample comprises of 397 individuals (188 males and 209 females). Among the 12.84
Short ReportGenetic variation at three VNTR loci (D1S80, Apob and D17S5) in two tribal populations of Andhra Pradesh, India
This study reports the genetic variation at three variable number of tandem repeat (VNTR) loci (APOB, D17S5 and D1S80) in two tribes (Thoti and Kolam) of Andhra Pradesh, India. Kolams constitute 1% of the total scheduled tribal population of Andhra Pradesh, while Thoti is a numerically small tribe. All three genetic loci were genotyped using the polymerase chain reaction (PCR) technique and were polymorphic in both populations. At the D1S80 locus…
Study of Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Anemia Among the Tamil Brahmins of Delhi
The distribution of G-6-PD deficiency and sickle cell anemia was studied among the Tamil Brahmins of Delhi. Blood samples were collected from 147 individuals out of whom 68 were males and 79 females. The detection of G-6-PD deficiency was done by Methemoglobin reduction test. Slide test using 2 percent sodium metabisulphite was used for detection of sickle cell trait. Low frequency of 2.72 percent G-6-PD deficient individuals was observed. Sickle…
MTHFR C677T polymorphisms among the Ahirs and Jats of Haryana (India)
Methylenetetrahydrofolate reductase (MTHFR) is a vital enzyme catalyzing the nicotinamide adenine dinucleotide phosphate (NADPH) linked reduction of 5,10‐methylenetetrahydrofolate to 5‐methylenetetrahydrofolate, which serves as cofactor in methylation of homocysteine to methionine. Three clinically important mutations of the MTHFR gene namely C677T , A1298C , and T1317C are reported to be associated with various pathological conditions. The prese…
G6PD Deficiency, Sickle Cell Trait, Haptoglobin and Transferrin Polymorphisms among Koyadoras and Nayakpods of Andhra Pradesh
The present study was carried out among two tribal populations residing in Khammam district of Andhra Pradesh, South India. A sample of 132 Koyadora and 40 Nayakpod individuals of all ages were collected for the purpose of screening for the glucose-6-phosphate dehydrogenase deficiency, haptoglobins, transferrins and sickle cell trait
Haptoglobin Polymorphism among Warli Tribe of Dadra Nagar Haveli, India
Haptoglobin (HP) is a protein that is well known for its hemoglobin (HB)-binding property. Data are presented on this polymorphic marker in a sample of 100 subjects belonging to the Warli tribe inhabiting Dadra and Nagar Haveli in Western India. The incidence of the HP* 1 allele was found to be 0.04 – lowest so far reported in Western and South India. The significance of the present study is elucidated with the prevalence of malaria and cases of …
Diversified genomic contribution among south Indian populations–A study on four endogamous groups of Andhra Pradesh
Although the presently studied populations of Andhra Pradesh have heterozygosity similar to that of Nilgiri hill populations, the former are more closely placed on the PCO plot than the latter, who are more scattered. Also the gene differentiation (Gst) of the former is much lower than that of the latter, indicating considerable regional variation in the inflow of genes from diverse ethnic groups within south India
Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Hemoglobin among the Warli Tribe of Dadra and Nagar Haveli
Anthropologists have always used Glucose-6-Phosphate dehydrogenase (G6PD) deficiency and sickle cell haemoglobin to trace human evolution and migratory histories of populations. The present study deals with the screening of these markers among the Warli population of Dadra and Nagar Haveli. The study aims to enhance the knowledge in the realm of population genetics vis-à-vis these two loci. Of the 79 males studied, 8 (10.1%) were found to be G6PD…
Surname Repetition in Three Population Groups of Andhra Pradesh: Kolam, Koya and Kuruma
The studies on surnames give information regarding origin, migration, evolution and variation within and between populations. Lasker (1988) noted that the distribution of surnames reflects the effect of mate choice on a population’s genetic structure. The present study on surname repetition is done with the aim of assessing genetic homogeneity/heterogeneity among the Kolam (primitive tribe), Koya (tribal group) and Kuruma (Caste group) population…
Incidence of NESTROFT-Positives and Haemoglobin S among the Jats and Brahmins of Sampla, Haryana
Nestroft is an uncumbersome and inexpensive test for the detection of haemoglobinopathies and thalassaemias. Here we report the incidence of positives and negatives with respect to this test as well as sickle cell trait among the Jats and Brahmins of Sampla, Haryana. Low percentages of Nestroft-positives and sickle cell trait suggest a low frequency of haemoglobin abnormalities, including thalassaemia, among them
Haptoglobin Polymorphism among Brahmins of Solan District Himachal Pradesh
Haptoglobin is a plasma glycoprotein that binds free hemoglobin with high affinity and prevents the loss of iron. In the present study 83 unrelated individuals from the Brahmin community of Solan District of Himachal Pradesh, were screened for haptoglobin polymorphism. Haptoglobin was found to be polymorphic in the selected population but the system was not found to be in Hardy Weinberg Equilibrium (÷2 = 10.83) due to the over representation of H…
Brief communication: Allelic and haplotypic structure at the DRD2 locus among five North Indian caste populations
The dopamine D2 receptor (DRD2) gene, with its known human‐specific derived alleles that can facilitate haplotype reconstruction, presents an important locus for anthropological studies. The three sites ( TaqIA , TaqIB , and TaqID ) of the DRD2 gene are widely studied in various world populations. However, no work has been previously published on DRD2 gene polymorphisms among North Indian populations. Thus, the present study attempts to understan…
Glucose-6-Phosphate Dehydrogenase Deficiency among the Rajputs and Brahmins of Solan District, Himachal Pradesh
G6PD deficiency is a common hemolytic genetic disorder whose frequency varies from population to population. The present study aims at screening G6PD deficiency among the Rajputs and Brahmins of Kasauli Tehsil (Solan district), Himachal Pradesh and to compare the results with the available data of other neighbouring caste populations. 1.54 % of the Rajput males and 2.12% of the Brahmin males screened were found to be G6PD deficient. The G6PD*def …
Genetic sketch of the six population groups of Rajasthan: A Study Based on 12 Autosomal Loci
Rajasthan lies on the northwest border of India, and has acted as a major route for human movements since prehistoric and historic times. The present study was conducted to gain an insight into inter-and intrapopulation affinities or variations among the six population groups of Rajasthan. DNA samples from 221 unrelated individuals belonging to six endogamous population groups of Rajasthan, including both tribal (Bhil, Damaria, Garasia, Mina and …
The association of non-HDL cholesterol with the presence of metabolic syndrome in North Indian subjects with and without CAD
TG and HDL-C are established risk components included in the characterization of MetS; but significant association of non-HDL-C with MetS in the present study is a key finding. The study focuses on the use of non-HDL-C as a simple screening tool to identify individuals with clustering metabolic abnormalities which increase the propensity for CAD
Common genetic heritage and admixture among Indian population groups as revealed by mtDNA markers
The present study determines the inter-and intra-population affinities or variations among the diverse population groups of India. The major goal of the present study was to understand the peopling of India and its role in the peopling of Southeast Asia using 11 restriction fragment length polymorphism (RFLP) mitochondrial DNA (mtDNA) markers. A total of 950 unrelated individuals belonging to 19 population groups having varied ethnic, linguistic,…
Isonymy and repeated pairs of surnames among the Muslims of Manipur, India
Medicine (33 works) · Demography (29 works) · Population (29 works) · Biology (23 works) · Internal Medicine (20 works) · Demography (17 works) · Environmental health (15 works) · Genetics (15 works) · Geography (12 works) · Sociology (11 works)