Common genetic heritage and admixture among Indian population groups as revealed by mtDNA markers

Bibliographic Data

ID6135550
AuthorsYaiphaba Sanjenbam (0000-0002-2914-0264, Vidyasagar University), Sanjenbam Yaiphaba Meitei (Vidyasagar University), Khangembam Somibabu Meitei (University of Delhi), Benrithung Murry (0000-0002-8789-2229, University of Delhi), Prakash Ranjan Mondal (University of Delhi), Kallur N Saraswathy (0000-0002-0826-9675, University of Delhi), Pradeep Kumar Ghosh (University of Delhi), M P Sachdeva (0000-0001-5439-1746, Anthropological Survey of India)
Year2012
Volume120
Issue3
Pages227-234
Publication date2012-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnthropological Science (JOURNAL)
Journal identifiersISSN: 0918-7960 • E-ISSN: 1348-8570
PublisherAnthropological Society of Nippon (PUBLISHER • JP)
DOI10.1537/ase.120730
OpenAlexW2089545482
LanguageEN
References cited29

The present study determines the inter-and intra-population affinities or variations among the diverse population groups of India. The major goal of the present study was to understand the peopling of India and its role in the peopling of Southeast Asia using 11 restriction fragment length polymorphism (RFLP) mitochondrial DNA (mtDNA) markers. A total of 950 unrelated individuals belonging to 19 population groups having varied ethnic, linguistic, and geographic backgrounds were chosen for the present study. All the studied sites, except HpaI 3592, are found to be polymorphic in the data set. High frequencies of M haplogroup are found among the South Indian populations, whereas N haplogroup is found to be high among the North Indian populations. Sub-haplogroups C and D of M are found only in the Tibeto-Burman-speaking Northeast population groups, suggesting their probable migration from Central Asia. Sub-haplogroups A and B of N are shared by both Northeast and North Indian population groups. The sub-haplogroups of M and N are absent among the South Indian and East Indian populations except the Thoti of the South India Dravidian tribe. The Northeast Indian populations exhibit the highest haplotypic diversity, whereas the South and East Indian populations have the lowest haplotypic diversity. The study provides evidence for a common maternal genetic substratum of Indian populations with probable differential admixture from Eurasia, i.e Europe and Asia, with a decreasing trend from North to South India. Sub-haplogroups of M and N and 9 bp deletion frequency patterns suggest gene flow from East Asia to India was restricted only to Northeast India and not suggest significant movement of people from India to East Asia through Northeast India

Allele · Biology · Evolutionary biology · Gene · Gene pool · Genetic diversity · Geography · Haplogroup · Haplotype · Human mitochondrial DNA haplogroup · Population · Demography · Forensic and Genetic Research · Molecular Biology Techniques and Applications · Race, Genetics, and Society · Genetics

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